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Select item 70267711.

Roquin-1 Regulates Macrophage Immune Response and Participates in Hepatic Ischemia–Reperfusion Injury

Lei Zheng, Wei Ling, Deming Zhu, Zhi Li, Lianbao Kong

J Immunol. 2020 Mar 1; 204(5): 1322–1333. Published online 2020 Jan 29. doi: 10.4049/jimmunol.1900053

PMCID:: PMC7026771

Abstract Article PDF–2.5M

Select item 64783262.

Structural and diffusion weighted MRI demonstrates responses to ibrutinib in a mouse model of follicular helper (Tfh) T-cell lymphoma

Rebecca L. Allchin, Michael E. Kelly, Sami Mamand, Anthony G. Doran, Thomas Keane, Matthew J. Ahearne, Simon D. Wagner

PLoS One. 2019; 14(4): e0215765. Published online 2019 Apr 23. doi: 10.1371/journal.pone.0215765

PMCID:: PMC6478326

Abstract Article PDF–1.1M

Select item 40172153.

Hematopoietic not systemic impairment of Roquin expression accounts for intestinal inflammation in Roquin-deficient mice

Dina Montufar-Solis, Nadarajah Vigneswaran, Niyati Nakra, Jeremy S. Schaefer, John R. Klein

Sci Rep. 2014; 4: 4920. Published online 2014 May 12. doi: 10.1038/srep04920

PMCID:: PMC4017215

Abstract Article PDF–1.5M

Select item 39146404.

Investigation into the prevalence of a novel dendritic-like cell subset in vivo

Kristin Lisa Griffiths, Jonathan Kah Huat Tan, Helen Christine O’Neill

J Cell Mol Med. 2013 Dec; 17(12): 1608–1618. Published online 2013 Nov 19. doi: 10.1111/jcmm.12174

PMCID:: PMC3914640

Abstract Article PDF–418K

Select item 35815525.

Small Intestine Inflammation in Roquin-Mutant and Roquin-Deficient Mice

Jeremy S. Schaefer, Dina Montufar-Solis, Niyati Nakra, Nadarajah Vigneswaran, John R. Klein

PLoS One. 2013; 8(2): e56436. Published online 2013 Feb 25. doi: 10.1371/journal.pone.0056436

PMCID:: PMC3581552

Abstract Article PDF–3.8M

Select item 35167706.

Enforced Expression of Roquin Protein in T Cells Exacerbates the Incidence and Severity of Experimental Arthritis

Young Rae Ji, Hei Jung Kim, Dong Hoon Yu, Ki Beom Bae, Seo Jin Park, Jun Koo Yi, Nari Kim, Si Jun Park, Keon Bong Oh, Sung Soo Hwang, Sanggyu Lee, Sung-Hyun Kim, Myoung Ok Kim, Jeong Woong Lee, Zae Young Ryoo

J Biol Chem. 2012 Dec 7; 287(50): 42269–42277. Published online 2012 Oct 12. doi: 10.1074/jbc.M112.374835

PMCID:: PMC3516770

Abstract Article PDF–2.1M

Select item 106913447.

Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity

Henrik Schmidt, Timsse Raj, Thomas J. O'Neill, Andreas Muschaweckh, Florian Giesert, Arlinda Negraschus, Kai P. Hoefig, Gesine Behrens, Lena Esser, Christina Baumann, Regina Feederle, Carlos Plaza-Sirvent, Arie Geerlof, Andreas Gewies, Sophie E. Isay, Jürgen Ruland, Ingo Schmitz, Wolfgang Wurst, Thomas Korn, Daniel Krappmann, Vigo Heissmeyer

Proc Natl Acad Sci U S A. 2023 Nov 28; 120(48): e2309205120. Published online 2023 Nov 21. doi: 10.1073/pnas.2309205120

PMCID:: PMC10691344

Abstract Article PDF–2.0M

Select item 64356538.

Inhibition of IL-17 ameliorates systemic lupus erythematosus in Roquin^san/san mice through regulating the balance of TFH cells, GC B cells, Treg and Breg

Seon-yeong Lee, Seung Hoon Lee, Hyeon-Beom Seo, Jun-Geol Ryu, KyungAh Jung, Jeong Won Choi, JooYeon Jhun, Jin-Sil Park, Ji Ye Kwon, Seung-Ki Kwok, Jeehee Youn, Sung-Hwan Park, Mi-La Cho

Sci Rep. 2019; 9: 5227. Published online 2019 Mar 26. doi: 10.1038/s41598-019-41534-1

PMCID:: PMC6435653

Abstract Article PDF–6.1M

Select item 59927919.

Combinatory treatment using tacrolimus and a STAT3 inhibitor regulate Treg cells and plasma cells

Jin-Sil Park, Sung-Min Kim, Sun-Hee Hwang, Si-Young Choi, Ji Ye Kwon, Seung-Ki Kwok, Mi-La Cho, Sung-Hwan Park

Int J Immunopathol Pharmacol. 2018 Mar-Dec; 32: 2058738418778724. Published online 2018 Jun 6. doi: 10.1177/2058738418778724

PMCID:: PMC5992791

Abstract Article PDF–826K

Select item 557052610.

Modulation of Roquin function in myeloid cells reduces Mycobacterium tuberculosis induced inflammation

Gayathri Nagalingam, Carola G. Vinuesa, Warwick J Britton, Bernadette M. Saunders

J Immunol. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: J Immunol. 2017 Sep 1; 199(5): 1796–1804. Published online 2017 Jul 26. doi: 10.4049/jimmunol.1602069

PMCID:: PMC5570526

Abstract Article PDF–2.7M

Select item 477764911.

Roquin – a multifunctional regulator of immune homeostasis

J. S. Schaefer, J. R. Klein

Genes Immun. Author manuscript; available in PMC 2016 Jun 17.

Published in final edited form as: Genes Immun. 2016 Mar; 17(2): 79–84. Published online 2015 Dec 17. doi: 10.1038/gene.2015.58

PMCID:: PMC4777649

Abstract Article PDF–343K

Select item 471684112.

Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation

Roybel R Ramiscal, Ian A Parish, Robert S Lee-Young, Jeffrey J Babon, Julianna Blagih, Alvin Pratama, Jaime Martin, Naomi Hawley, Jean Y Cappello, Pablo F Nieto, Julia I Ellyard, Nadia J Kershaw, Rebecca A Sweet, Christopher C Goodnow, Russell G Jones, Mark A Febbraio, Carola G Vinuesa, Vicki Athanasopoulos

eLife. 2015; 4: e08698. Published online 2015 Oct 23. doi: 10.7554/eLife.08698

PMCID:: PMC4716841

Abstract Article PDF–3.5M

Select item 369250513.

ROQUIN/RC3H1 Alterations Are Not Found in Angioimmunoblastic T-Cell Lymphoma

Tiphanie Auguste, Marion Travert, Karin Tarte, Patricia Amé-Thomas, Catherine Artchounin, Nadine Martin-Garcia, Aurélien de Reynies, Laurence de Leval, Philippe Gaulard, Marie-Hélène Delfau-Larue

PLoS One. 2013; 8(6): e64536. Published online 2013 Jun 25. doi: 10.1371/journal.pone.0064536

PMCID:: PMC3692505

Abstract Article PDF–430K

Select item 269913214.

Follicular helper T cells are required for systemic autoimmunity

Michelle A. Linterman, Robert J. Rigby, Raphael. K. Wong, Di Yu, Robert Brink, Jennifer L. Cannons, Pamela L. Schwartzberg, Matthew C. Cook, Giles D. Walters, Carola G. Vinuesa

J Exp Med. 2009 Mar 16; 206(3): 561–576. doi: 10.1084/jem.20081886

PMCID:: PMC2699132

Abstract Article PDF–9.1M

Select item 811092915.

Programmed Death-Ligand 1 Expression Potentiates the Immune Modulatory Function Of Myeloid-Derived Suppressor Cells in Systemic Lupus Erythematosus

Min-Jung Park, Jin-Ah Baek, Jeong Won Choi, Se Gwang Jang, Da-Som Kim, Sung-Hwan Park, Mi-La Cho, Seung-Ki Kwok

Front Immunol. 2021; 12: 606024. Published online 2021 Apr 27. doi: 10.3389/fimmu.2021.606024

PMCID:: PMC8110929

Abstract Article PDF–7.8M

Select item 614589216.

Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation

Katharina Essig, Nina Kronbeck, Joao C. Guimaraes, Claudia Lohs, Andreas Schlundt, Anne Hoffmann, Gesine Behrens, Sven Brenner, Joanna Kowalska, Cristina Lopez-Rodriguez, Jacek Jemielity, Helmut Holtmann, Kristin Reiche, Jörg Hackermüller, Michael Sattler, Mihaela Zavolan, Vigo Heissmeyer

Nat Commun. 2018; 9: 3810. Published online 2018 Sep 19. doi: 10.1038/s41467-018-06184-3

PMCID:: PMC6145892

Abstract Article PDF–3.3M

Select item 603467917.

Role for IL-10 in the transcriptional regulation of Roquin-1

Jeremy S. Schaefer, Dina Montufar-Solis, John R. Klein

Gene. Author manuscript; available in PMC 2018 Jul 6.

Published in final edited form as: Gene. 2014 Oct 1; 549(1): 134–140. Published online 2014 Jul 23. doi: 10.1016/j.gene.2014.07.056

PMCID:: PMC6034679

Abstract Article PDF–721K

Select item 137086818.

Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body

JIANG HONG YU, WEI-HONG YANG, TOD GULICK, KENNETH D. BLOCH, DONALD B. BLOCH

RNA. 2005 Dec; 11(12): 1795–1802. doi: 10.1261/rna.2142405

PMCID:: PMC1370868

Abstract Article PDF–556K

Select item 801951519.

Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice

Dina Montufar-Solis, Alexander Williams, Nadarajah Vigneswaran, John R. Klein

Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Apr 4.

Published in final edited form as: Biochem Biophys Res Commun. 2017 Jan 29; 483(1): 590–595. Published online 2016 Dec 21. doi: 10.1016/j.bbrc.2016.12.099

PMCID:: PMC8019515

Abstract Article PDF–1.4M

Select item 314206820.

Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells

Diego G. Silva, Stephen R. Daley, Jennifer Hogan, Sau K. Lee, Charis E. Teh, Daniel Y. Hu, Kong-Peng Lam, Christopher C. Goodnow, Carola G. Vinuesa

Diabetes. 2011 Aug; 60(8): 2102–2111. Published online 2011 Jul 18. doi: 10.2337/db10-1344

PMCID:: PMC3142068

Abstract Article PDF–1.9M

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