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Select item 72138021.

Intestinal alkaline phosphatase targets the gut barrier to prevent aging

Florian Kühn, Fatemeh Adiliaghdam, Paul M. Cavallaro, Sulaiman R. Hamarneh, Amy Tsurumi, Raza S. Hoda, Alexander R. Munoz, Yashoda Dhole, Juan M. Ramirez, Enyu Liu, Robin Vasan, Yang Liu, Ehsan Samarbafzadeh, Rocio A. Nunez, Matthew Z. Farber, Vanita Chopra, Madhu S. Malo, Laurence G. Rahme, Richard A. Hodin

JCI Insight. 2020 Mar 26; 5(6): e134049. Published online 2020 Mar 26. doi: 10.1172/jci.insight.134049

PMCID:: PMC7213802

Abstract Article PDF–10M

Select item 84058802.

Activation of innate immunity during development induces unresolved dysbiotic inflammatory gut and shortens lifespan

Kyoko Yamashita, Ayano Oi, Hina Kosakamoto, Toshitaka Yamauchi, Hibiki Kadoguchi, Takayuki Kuraishi, Masayuki Miura, Fumiaki Obata

Dis Model Mech. 2021 Sep 1; 14(9): dmm049103. Published online 2021 Aug 27. doi: 10.1242/dmm.049103

PMCID:: PMC8405880

Abstract Article

Select item 45861003.

Endurance exercise and selective breeding for longevity extend Drosophila healthspan by overlapping mechanisms

Alyson Sujkowski, Brian Bazzell, Kylie Carpenter, Robert Arking, Robert J Wessells

Aging (Albany NY) 2015 Aug; 7(8): 535–550. Published online 2015 Aug 8. doi: 10.18632/aging.100789

PMCID:: PMC4586100

Abstract Article PDF–2.1M

Select item 39184344.

Genomic Response to Selection for Postponed Senescence in Drosophila

Rhonda H. Wilson, Chao Qiang Lai, Richard F. Lyman, Trudy F. C. Mackay

Mech Ageing Dev. Author manuscript; available in PMC 2014 Feb 9.

Published in final edited form as: Mech Ageing Dev. 2013 Mar; 134(0): 79–88. Published online 2012 Dec 21. doi: 10.1016/j.mad.2012.11.003

PMCID:: PMC3918434

Abstract Article PDF–1.0M

Select item 69553045.

An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity

Chiwei Xu, Brian Franklin, Hong-Wen Tang, Yannik Regimbald-Dumas, Yanhui Hu, Justine Ramos, Justin A. Bosch, Christians Villalta, Xi He, Norbert Perrimon

Proc Natl Acad Sci U S A. 2020 Jan 7; 117(1): 464–471. Published online 2019 Dec 18. doi: 10.1073/pnas.1900103117

PMCID:: PMC6955304

Abstract Article PDF–1.9M

Select item 40692636.

Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster

Rachel Whitaker, M. Pilar Gil, Feifei Ding, Marc Tatar, Stephen L. Helfand, Nicola Neretti

Aging (Albany NY) 2014 May; 6(5): 355–368. Published online 2014 May 14. doi: 10.18632/aging.100662

PMCID:: PMC4069263

Abstract Article PDF–2.4M

Select item 45689777.

Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress

Amalia Icreverzi, Aida Flor A de la Cruz, David W Walker, Bruce A Edgar

Aging Cell. 2015 Oct; 14(5): 896–906. Published online 2015 Jul 29. doi: 10.1111/acel.12376

PMCID:: PMC4568977

Abstract Article PDF–2.1M

Select item 39862218.

Drosophila Microbiota Modulates Host Metabolic Gene Expression via IMD/NF-κB Signaling

Berra Erkosar Combe, Arnaud Defaye, Noémie Bozonnet, Denis Puthier, Julien Royet, François Leulier

PLoS One. 2014; 9(4): e94729. Published online 2014 Apr 14. doi: 10.1371/journal.pone.0094729

Correction in:: PLoS One. 2014; 9(7): e104120.

PMCID:: PMC3986221

Abstract Article PDF–1010K

Select item 18391319.

Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila

Yongsheng Bai, Claudio Casola, Cédric Feschotte, Esther Betrán

Genome Biol. 2007; 8(1): R11. Published online 2007 Jan 18. doi: 10.1186/gb-2007-8-1-r11

PMCID:: PMC1839131

Abstract Article PDF–274K

Select item 658746110.

The gut microbiome participates in transgenerational inheritance of low‐temperature responses in Drosophila melanogaster

Aman Zare, Anna‐Mia Johansson, Edvin Karlsson, Nicolas Delhomme, Per Stenberg

FEBS Lett. 2018 Dec; 592(24): 4078–4086. Published online 2018 Nov 15. doi: 10.1002/1873-3468.13278

PMCID:: PMC6587461

Abstract Article PDF–479K

Select item 719356411.

CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila

Menghua Wu, Xuedi Zhang, Wei Wei, Li Long, Sainan An, Guanjun Gao

Sci Rep. 2020; 10: 7383. Published online 2020 Apr 30. doi: 10.1038/s41598-020-64253-4

PMCID:: PMC7193564

Abstract Article PDF–1.8M

Select item 304921512.

Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat

Francesco Napoletano, Simona Occhi, Piera Calamita, Vera Volpi, Eric Blanc, Bernard Charroux, Julien Royet, Manolis Fanto

EMBO J. 2011 Mar 2; 30(5): 945–958. Published online 2011 Jan 28. doi: 10.1038/emboj.2011.1

PMCID:: PMC3049215

Abstract Article PDF–3.2M

Select item 456802513.

Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions

Albert J. Erives

Dev Genes Evol. 2015; 225(5): 259–273. Published online 2015 Jul 15. doi: 10.1007/s00427-015-0508-1

PMCID:: PMC4568025

Abstract Article PDF–2.8M

Select item 492804714.

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair

Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999

PMCID:: PMC4928047

Abstract Article PDF–3.1M

Select item 304044115.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 353067716.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 570780517.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900218.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 435288719.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 282505320.

Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin

Roger A. Hoskins, Joseph W. Carlson, Cameron Kennedy, David Acevedo, Martha Evans-Holm, Erwin Frise, Kenneth H. Wan, Soo Park, Maria Mendez-Lago, Fabrizio Rossi, Alfredo Villasante, Patrizio Dimitri, Gary H. Karpen, Susan E. Celniker

Science. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1625–1628. doi: 10.1126/science.1139816

PMCID:: PMC2825053

Abstract Article PDF–858K

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