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Select item 67338711.

Spatial oxidation of L-plastin downmodulates actin-based functions of tumor cells

Emre Balta, Robert Hardt, Jie Liang, Henning Kirchgessner, Christian Orlik, Beate Jahraus, Stefan Hillmer, Stefan Meuer, Katrin Hübner, Guido H. Wabnitz, Yvonne Samstag

Nat Commun. 2019; 10: 4073. Published online 2019 Sep 9. doi: 10.1038/s41467-019-11909-z

PMCID:: PMC6733871

Abstract Article PDF–6.2M

Select item 53225262.

Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer

Nao Koide, Atsushi Kasamatsu, Yosuke Endo-Sakamoto, Sho Ishida, Toshihiro Shimizu, Yasushi Kimura, Isao Miyamoto, Shusaku Yoshimura, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa

Sci Rep. 2017; 7: 43379. Published online 2017 Feb 23. doi: 10.1038/srep43379

PMCID:: PMC5322526

Abstract Article PDF–1.5M

Select item 38996283.

Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation

Selina M Riplinger, Guido H Wabnitz, Henning Kirchgessner, Beate Jahraus, Felix Lasitschka, Bianca Schulte, Gabri van der Pluijm, Geertje van der Horst, Günter J Hämmerling, Inaam Nakchbandi, Yvonne Samstag

Mol Cancer. 2014; 13: 10. Published online 2014 Jan 18. doi: 10.1186/1476-4598-13-10

PMCID:: PMC3899628

Abstract Article PDF–1.6M

Select item 111136074.

Nanobody-induced perturbation of LFA-1/L-plastin phosphorylation impairs MTOC docking, immune synapse formation and T cell activation

Sarah De Clercq, Olivier Zwaenepoel, Evelien Martens, Joël Vandekerckhove, Aude Guillabert, Jan Gettemans

Cell Mol Life Sci. 2013 Mar; 70(5): 909–922. Published online 2012 Sep 23. doi: 10.1007/s00018-012-1169-0

PMCID:: PMC11113607

Abstract Article PDF–860K

Select item 60322435.

Inhibition of HIF1α-Dependent Upregulation of Phospho-l-Plastin Resensitizes Multiple Myeloma Cells to Frontline Therapy

Manon Bosseler, Vanessa Marani, Angelina Broukou, Amandine Lequeux, Tony Kaoma, Vincent Schlesser, Jean-Hugues François, Valérie Palissot, Guy J. Berchem, Nasséra Aouali, Bassam Janji

Int J Mol Sci. 2018 Jun; 19(6): 1551. Published online 2018 May 23. doi: 10.3390/ijms19061551

PMCID:: PMC6032243

Abstract Article PDF–1.8M

Select item 56805696.

AP4 modulated by the PI3K/AKT pathway promotes prostate cancer proliferation and metastasis of prostate cancer via upregulating L-plastin

Changhao Chen, Qingqing Cai, Wang He, Thomas B Lam, Jianxun Lin, Yue Zhao, Xu Chen, Peng Gu, Hao Huang, Miaoxin Xue, Hao Liu, Feng Su, Jian Huang, Jianping Zheng, Tianxin Lin

Cell Death Dis. 2017 Oct; 8(10): e3060. Published online 2017 Oct 5. doi: 10.1038/cddis.2017.437

PMCID:: PMC5680569

Abstract Article PDF–7.1M

Select item 55385477.

Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia

Lili Wang, Jean Fan, Joshua M. Francis, George Georghiou, Sarah Hergert, Shuqiang Li, Rutendo Gambe, Chensheng W. Zhou, Chunxiao Yang, Sheng Xiao, Paola Dal Cin, Michaela Bowden, Dylan Kotliar, Sachet A. Shukla, Jennifer R. Brown, Donna Neuberg, Dario R. Alessi, Cheng-Zhong Zhang, Peter V. Kharchenko, Kenneth J. Livak, Catherine J. Wu

Genome Res. 2017 Aug; 27(8): 1300–1311. doi: 10.1101/gr.217331.116

PMCID:: PMC5538547

Abstract Article PDF–792K

Select item 53959368.

L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration

Esther Serrano-Pertierra, Eva Cernuda-Morollón, Tomáš Brdička, Václav Hoøejši, Carlos López-Larrea

J Leukoc Biol. 2014 Sep; 96(3): 437–445. doi: 10.1189/jlb.2A1013-564R

PMCID:: PMC5395936

Abstract Article

Select item 48614819.

Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia

Isabel Van Audenhove, Majken Denert, Ciska Boucherie, Leen Pieters, Maria Cornelissen, Jan Gettemans

J Biol Chem. 2016 Apr 22; 291(17): 9148–9160. Published online 2016 Mar 4. doi: 10.1074/jbc.M115.706937

PMCID:: PMC4861481

Abstract Article PDF–3.6M

Select item 453393810.

Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium

Sean Harrison, Sarah J. Lewis, Amanda J. Hall, Dragana Vuckovic, Giorgia Girotto, Richard M. Martin, Josephine C. Adams

BMC Med Genomics. 2015; 8: 48. Published online 2015 Aug 12. doi: 10.1186/s12920-015-0112-2

PMCID:: PMC4533938

Abstract Article PDF–597K

Select item 395308911.

Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing

Jason A. Dubovsky, Danielle L. Chappell, Bonnie K. Harrington, Kitty Agrawal, Leslie A. Andritsos, Joseph M. Flynn, Jeffrey A. Jones, Michael E. Paulaitis, Brad Bolon, Amy J. Johnson, John C. Byrd, Natarajan Muthusamy

Blood. 2013 Nov 7; 122(19): 3308–3316. Prepublished online 2013 Sep 5. doi: 10.1182/blood-2013-05-504597

PMCID:: PMC3953089

Abstract Article

Select item 394596912.

Plastin polymorphisms predict genderand stage-specific colon cancer recurrence after adjuvant chemotherapy

Yan Ning, Armin Gerger, Wu Zhang, Diana L Hanna, Dongyun Yang, Thomas Winder, Takeru Wakatsuki, Melissa J Labonte, Sebastian Stintzing, Nico Volz, Yu Sunakawa, Stefan Stremitzer, Rita El-Khoueiry, Heinz-Josef Lenz

Mol Cancer Ther. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Mol Cancer Ther. 2014 Feb; 13(2): 528–539. Published online 2013 Oct 29. doi: 10.1158/1535-7163.MCT-13-0646

PMCID:: PMC3945969

Abstract Article PDF–325K

Select item 382884413.

The actin filament cross-linker L-plastin confers resistance to TNF-α in MCF-7 breast cancer cells in a phosphorylation-dependent manner

Bassam Janji, Laurent Vallar, Ziad Al Tanoury, François Bernardin, Guillaume Vetter, Elisabeth Schaffner-Reckinger, Guy Berchem, Evelyne Friederich, Salem Chouaib

J Cell Mol Med. 2010 Jun; 14(6a): 1264–1275. Published online 2009 Oct 3. doi: 10.1111/j.1582-4934.2009.00918.x

PMCID:: PMC3828844

Abstract Article PDF–1.0M

Select item 310077314.

Priming of Eosinophil by Granulocyte-Macrophage Colony Stimulating Factor is Mediated by Protein Kinase C βII Phosphorylated L-Plastin

Konrad Pazdrak, Travis W. Young, Christof Straub, Susan Stafford, Alexander Kurosky

J Immunol. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: J Immunol. 2011 Jun 1; 186(11): 6485–6496. Published online 2011 Apr 27. doi: 10.4049/jimmunol.1001868

PMCID:: PMC3100773

Abstract Article PDF–2.3M

Select item 282140015.

Quantitative Kinetic Study of the Actin-Bundling Protein L-Plastin and of Its Impact on Actin Turn-Over

Ziad Al Tanoury, Elisabeth Schaffner-Reckinger, Aliaksandr Halavatyi, Céline Hoffmann, Michèle Moes, Ermin Hadzic, Marie Catillon, Mikalai Yatskou, Evelyne Friederich

PLoS One. 2010; 5(2): e9210. Published online 2010 Feb 15. doi: 10.1371/journal.pone.0009210

PMCID:: PMC2821400

Abstract Article PDF–1.6M

Select item 212029816.

Functional differences between L- and T-plastin isoforms

J Cell Biol. 1994 Dec 2; 127(6): 1995–2008. doi: 10.1083/jcb.127.6.1995

PMCID:: PMC2120298

Summary PDF–5.5M

Select item 36229317.

Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain.

C S Lin, R H Aebersold, J Leavitt

Mol Cell Biol. 1990 Apr; 10(4): 1818–1821. doi: 10.1128/mcb.10.4.1818

PMCID:: PMC362293

Summary Page Browse PDF–804K

Select item 35861318.

Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney.

C S Lin, W Shen, Z P Chen, Y H Tu, P Matsudaira

Mol Cell Biol. 1994 Apr; 14(4): 2457–2467. doi: 10.1128/mcb.14.4.2457

PMCID:: PMC358613

Summary Page Browse PDF–3.2M

Select item 550082819.

miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin

Lizandra Jimenez, Jihyeon Lim, Berta Burd, Thomas M. Harris, Thomas J. Ow, Nicole Kawachi, Thomas J. Belbin, Ruth Angeletti, Michael B. Prystowsky, Geoffrey Childs, Jeffrey E. Segall

Am J Pathol. 2017 Jul; 187(7): 1523–1536. doi: 10.1016/j.ajpath.2017.02.019

PMCID:: PMC5500828

Abstract Article PDF–1.6M

Select item 219419820.

Plasmin Activates the Lymphangiogenic Growth Factors VEGF-C and VEGF-D

Bradley K. McColl, Megan E. Baldwin, Sally Roufail, Craig Freeman, Robert L. Moritz, Richard J. Simpson, Kari Alitalo, Steven A. Stacker, Marc G. Achen

J Exp Med. 2003 Sep 15; 198(6): 863–868. doi: 10.1084/jem.20030361