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Select item 76574771.

Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity

Yang Cheng, Jiadong Cai, Yuanyuan Fu, Congjing Feng, Yue Hao, Youheng Wei

Biol Open. 2020 Nov 15; 9(11): bio054999. Published online 2020 Nov 6. doi: 10.1242/bio.054999

PMCID:: PMC7657477

Abstract Article PDF–2.1M

Select item 41311792.

The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila

Y Wei, M A Lilly

Cell Death Differ. 2014 Sep; 21(9): 1460–1468. Published online 2014 May 2. doi: 10.1038/cdd.2014.63

PMCID:: PMC4131179

Abstract Article PDF–2.6M

Select item 51449573.

The GATOR1 Complex Regulates Metabolic Homeostasis and the Response to Nutrient Stress in Drosophila melanogaster

Youheng Wei, Brad Reveal, Weili Cai, Mary A. Lilly

G3 (Bethesda) 2016 Dec; 6(12): 3859–3867. Published online 2016 Sep 26. doi: 10.1534/g3.116.035337

PMCID:: PMC5144957

Abstract Article PDF–1.2M

Select item 42845574.

TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila

Youheng Wei, Brad Reveal, John Reich, Willem J. Laursen, Stefania Senger, Tanveer Akbar, Takako Iida-Jones, Weili Cai, Michal Jarnik, Mary A. Lilly

Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52): E5670–E5677. Published online 2014 Dec 15. doi: 10.1073/pnas.1419156112

PMCID:: PMC4284557

Abstract Article PDF–1.9M

Select item 81728525.

FKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila

Ying Zhou, Jian Guo, Xinyu Wang, Yang Cheng, Jianwen Guan, Priyam Barman, Ming-An Sun, Yuanyuan Fu, Wanhong Wei, Congjing Feng, Mary A. Lilly, Youheng Wei

Cell Death Dis. 2021 Jun; 12(6): 571. Published online 2021 Jun 2. doi: 10.1038/s41419-021-03860-z

PMCID:: PMC8172852

Abstract Article PDF–2.5M

Select item 99104876.

Wdr59 promotes or inhibits TORC1 activity depending on cellular context

Yingbiao Zhang, Chun-Yuan Ting, Shu Yang, John Reich, Karenne Fru, Mary A. Lilly

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2212330120. Published online 2022 Dec 28. doi: 10.1073/pnas.2212330120

PMCID:: PMC9910487

Abstract Article PDF–7.5M

Select item 90111297.

A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis

Elliot T. Martin, Patrick Blatt, Elaine Nguyen, Roni Lahr, Sangeetha Selvam, Hyun Ah M. Yoon, Tyler Pocchiari, Shamsi Emtenani, Daria E. Siekhaus, Andrea Berman, Gabriele Fuchs, Prashanth Rangan

Dev Cell. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Dev Cell. 2022 Apr 11; 57(7): 883–900.e10. doi: 10.1016/j.devcel.2022.03.005

PMCID:: PMC9011129

Abstract Article PDF–3.2M

Select item 109578978.

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3

PMCID:: PMC10957897

Abstract Article PDF–2.0M

Select item 68343689.

The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila

Youheng Wei, Lucia Bettedi, Chun-Yuan Ting, Kuikwon Kim, Yingbiao Zhang, Jiadong Cai, Mary A Lilly

eLife. 2019; 8: e42149. Published online 2019 Oct 25. doi: 10.7554/eLife.42149

PMCID:: PMC6834368

Abstract Article PDF–5.1M

Select item 486424110.

The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function

Weili Cai, Youheng Wei, Michal Jarnik, John Reich, Mary A. Lilly

PLoS Genet. 2016 May; 12(5): e1006036. Published online 2016 May 11. doi: 10.1371/journal.pgen.1006036

PMCID:: PMC4864241

Abstract Article PDF–6.9M

Select item 310883711.

A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole in Saccharomyces cerevisiae

Svetlana Dokudovskaya, Francois Waharte, Avner Schlessinger, Ursula Pieper, Damien P. Devos, Ileana M. Cristea, Rosemary Williams, Jean Salamero, Brian T. Chait, Andrej Sali, Mark C. Field, Michael P. Rout, Catherine Dargemont

Mol Cell Proteomics. 2011 Jun; 10(6): M110.006478. Published online 2011 Mar 31. doi: 10.1074/mcp.M110.006478

PMCID:: PMC3108837

Abstract Article PDF–2.7M

Select item 372865412.

A tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

Liron Bar-Peled, Lynne Chantranupong, Andrew D. Cherniack, Walter W. Chen, Kathleen A. Ottina, Brian C. Grabiner, Eric D. Spear, Scott L. Carter, Matthew Meyerson, David M. Sabatini

Science. Author manuscript; available in PMC 2013 Jul 31.

Published in final edited form as: Science. 2013 May 31; 340(6136): 1100–1106. doi: 10.1126/science.1232044

PMCID:: PMC3728654

Abstract Article PDF–2.5M

Select item 807915013.

Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

Hiroshi Nishida, Morihiro Okada, Lynna Yang, Tomomi Takano, Sho Tabata, Tomoyoshi Soga, Diana M Ho, Jongkyeong Chung, Yasuhiro Minami, Sa Kan Yoo

eLife. 2021; 10: e59809. Published online 2021 Apr 27. doi: 10.7554/eLife.59809

PMCID:: PMC8079150

Abstract Article PDF–6.6M

Select item 986008314.

Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs

Tommy H. Taslim, Abdiasis M. Hussein, Riya Keshri, Julien R. Ishibashi, Tung C. Chan, Bich N. Nguyen, Shuozhi Liu, Daniel Brewer, Stuart Harper, Scott Lyons, Ben Garver, Jimmy Dang, Nanditaa Balachandar, Samriddhi Jhajharia, Debra del Castillo, Julie Mathieu, Hannele Ruohola-Baker

Stem Cell Reports. 2023 Jan 10; 18(1): 269–288. Published online 2022 Dec 8. doi: 10.1016/j.stemcr.2022.11.004

PMCID:: PMC9860083

Abstract Article PDF–6.8M

Select item 285194715.

A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network

Andrea Lunardi, Giulio Di Minin, Paolo Provero, Marco Dal Ferro, Marcello Carotti, Giannino Del Sal, Licio Collavin

Proc Natl Acad Sci U S A. 2010 Apr 6; 107(14): 6322–6327. Published online 2010 Mar 22. doi: 10.1073/pnas.1002447107

PMCID:: PMC2851947

Abstract Article PDF–1.0M

Select item 440366716.

Transcription Factor Networks in Drosophila melanogaster

David Y. Rhee, Dong-Yeon Cho, Bo Zhai, Matthew Slattery, Lijia Ma, Julian Mintseris, Christina Y. Wong, Kevin P. White, Susan E. Celniker, Teresa M. Przytycka, Steven P. Gygi, Robert A. Obar, Spyros Artavanis-Tsakonas

Cell Rep. Author manuscript; available in PMC 2015 Apr 20.

Published in final edited form as: Cell Rep. 2014 Sep 25; 8(6): 2031–2043. Published online 2014 Sep 18. doi: 10.1016/j.celrep.2014.08.038

PMCID:: PMC4403667

Abstract Article PDF–1.3M

Select item 804227017.

Comprehensive Identification and Alternative Splicing of Microexons in Drosophila

Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu

Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602

PMCID:: PMC8042270

Abstract Article PDF–3.6M

Select item 696157818.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 427152719.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 285522120.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Apr 2.

Published in final edited form as: Cell. 2010 Apr 2; 141(1): 142–153. doi: 10.1016/j.cell.2010.02.023

PMCID:: PMC2855221

Abstract Article PDF–5.3M

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