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Select item 109285151.

Role of Wnt co-receptor LRP6 in triple negative breast cancer cell migration and invasion

Jinlu Ma, Wenyan Lu, Dongquan Chen, Bo Xu, Yonghe Li

J Cell Biochem. Author manuscript; available in PMC 2024 Mar 12.

Published in final edited form as: J Cell Biochem. 2017 Sep; 118(9): 2968–2976. Published online 2017 May 30. doi: 10.1002/jcb.25956

PMCID:: PMC10928515

Abstract Article PDF–1.7M

Select item 106244292.

A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease

Megan E. Jones, Johanna Büchler, Tom Dufor, Ernest Palomer, Samuel Teo, Nuria Martin-Flores, Katharina Boroviak, Emmanouil Metzakopian, Alasdair Gibb, Patricia C. Salinas

Sci Adv. 2023 Jan; 9(2): eabo7421. Published online 2023 Jan 13. doi: 10.1126/sciadv.abo7421

PMCID:: PMC10624429

Abstract Article PDF–1.8M

Select item 95684783.

An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family

Nuria Puente, Ana I. Vega, José L. Hernandez, Jose L. Fernandez-Luna, Jose A. Riancho

Osteoporos Int. 2022; 33(11): 2445–2448. Published online 2022 Jul 15. doi: 10.1007/s00198-022-06494-9

PMCID:: PMC9568478

Abstract Article PDF–564K

Select item 88787244.

circ-LRP6 contributes to osteosarcoma progression by regulating the miR-141-3p/HDAC4/HMGB1 axis

Yali Yu, Guixiang Dong, Zijun Li, Yan Zheng, Zhisong Shi, Guanghui Wang

Int J Oncol. 2022 Apr; 60(4): 38. Published online 2022 Feb 23. doi: 10.3892/ijo.2022.5328

PMCID:: PMC8878724

Abstract Article PDF–1.2M

Select item 84954065.

Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling

Li-Jie Chen, Xiu-Xian Lin, Jing Guo, Ying Xu, Song-Xia Zhang, Dan Chen, Qing Zhao, Jian Xiao, Guang-Hui Lian, Shi-Fang Peng, Dong Guo, Hong Yang, Yan Shu, Hong-Hao Zhou, Wei Zhang, Yao Chen

Int J Biol Sci. 2021; 17(14): 3936–3953. Published online 2021 Sep 21. doi: 10.7150/ijbs.63732

PMCID:: PMC8495406

Abstract Article PDF–2.5M

Select item 83730926.

Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes

Hei‐Man Chow, Jacquelyne Ka‐Li Sun, Ronald P. Hart, Kenneth King‐Yip Cheng, Clara H. L. Hung, Tsun‐Ming Lau, Kin‐Ming Kwan

Adv Sci (Weinh) 2021 Aug; 8(16): 2004993. Published online 2021 Jun 27. doi: 10.1002/advs.202004993

PMCID:: PMC8373092

Abstract Article PDF–8.7M

Select item 77389027.

Low-density lipoprotein receptor-related protein 6 regulates cardiomyocyte-derived paracrine signaling to ameliorate cardiac fibrosis

Xiang Wang, Yan Zou, Zhidan Chen, Yang Li, Le Pan, Ying Wang, Ming Liu, Chao Yin, Jian Wu, Chunjie Yang, Lei Zhang, Chenze Li, Zheyong Huang, Daowen Wang, Juying Qian, Junbo Ge, Yunzeng Zou, Hui Gong

Theranostics. 2021; 11(3): 1249–1268. Published online 2021 Jan 1. doi: 10.7150/thno.48787

PMCID:: PMC7738902

Abstract Article PDF–4.5M

Select item 72554868.

LRP6 is involved in the proliferation, migration and invasion of trophoblast cells via miR-346

Lu Zhang, Huihui Li, Mingbao Li, Wenxia Zhang, Zhou Yang, Shuquan Zhang

Int J Mol Med. 2020 Jul; 46(1): 211–223. Published online 2020 Apr 8. doi: 10.3892/ijmm.2020.4570

PMCID:: PMC7255486

Abstract Article PDF–2.9M

Select item 56369789.

LRP6 is identified as a potential prognostic marker for oral squamous cell carcinoma via MALDI-IMS

Yao Yuan, Xiaoyan Xie, Yuchen Jiang, Zihao Wei, Peiqi Wang, Fangman Chen, Xinyi Li, Chongkui Sun, Hang Zhao, Xin Zeng, Lu Jiang, Yu Zhou, Hongxia Dan, Mingye Feng, Rui Liu, Zhiyong Wang, Qianming Chen

Cell Death Dis. 2017 Sep; 8(9): e3035. Published online 2017 Sep 7. doi: 10.1038/cddis.2017.433

PMCID:: PMC5636978

Abstract Article PDF–5.6M

Select item 510257810.

Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6

Elsa Perrody, Laurence Abrami, Michal Feldman, Beatrice Kunz, Sylvie Urbé, F Gisou van der Goot

eLife. 2016; 5: e19083. Published online 2016 Oct 18. doi: 10.7554/eLife.19083

PMCID:: PMC5102578

Abstract Article PDF–762K

Select item 501823511.

Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis

Charlotte W. Ockeloen, Kriti D. Khandelwal, Karoline Dreesen, Kerstin U. Ludwig, Robert Sullivan, Iris A.L.M. van Rooij, Michelle Thonissen, Steven Swinnen, Milien Phan, Federica Conte, Nina Ishorst, Christian Gilissen, Laury RoaFuentes, Maartje van de Vorst, Arjen Henkes, Marloes Steehouwer, Ellen van Beusekom, Marjon Bloemen, Bruno Vankeirsbilck, Stefaan Bergé, Greet Hens, Joseph Schoenaers, Vincent Vander Poorten, Jasmien Roosenboom, An Verdonck, Koen Devriendt, Nel Roeleveldt, Shalini N. Jhangiani, Lisenka E.L.M. Vissers, James R. Lupski, Joep de Ligt, Johannes W. Von den Hoff, Rolph Pfundt, Han G. Brunner, Huiqing Zhou, Jill Dixon, Elisabeth Mangold, Hans van Bokhoven, Michael J. Dixon, Tjitske Kleefstra, Alexander Hoischen, Carine E.L. Carels

Genet Med. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Genet Med. 2016 Nov; 18(11): 1158–1162. Published online 2016 Mar 10. doi: 10.1038/gim.2016.10

PMCID:: PMC5018235

Abstract Article PDF–588K

Select item 496454412.

Mutant LRP6 Impairs Endothelial Cell Functions Associated with Familial Normolipidemic Coronary Artery Disease

Jian Guo, Yang Li, Yi-Hong Ren, Zhijun Sun, Jie Dong, Han Yan, Yujun Xu, Dao Wen Wang, Gu-Yan Zheng, Jie Du, Xiao-Li Tian

Int J Mol Sci. 2016 Jul; 17(7): 1173. Published online 2016 Jul 22. doi: 10.3390/ijms17071173

PMCID:: PMC4964544

Abstract Article PDF–1.7M

Select item 459691313.

Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia

Maarten P.G. Massink, Marijn A. Créton, Francesca Spanevello, Willem M.M. Fennis, Marco S. Cune, Sanne M.C. Savelberg, Isaäc J. Nijman, Madelon M. Maurice, Marie-José H. van den Boogaard, Gijs van Haaften

Am J Hum Genet. 2015 Oct 1; 97(4): 621–626. Published online 2015 Sep 17. doi: 10.1016/j.ajhg.2015.08.014