PMC Links for Gene (Select 4066) - PMC

Select item 92880511.

Super-enhancer profiling identifies novel critical and targetable cancer survival gene LYL1 in pediatric acute myeloid leukemia

Fang Fang, Jun Lu, Xu Sang, Yan-Fang Tao, Jian-Wei Wang, Zi-Mu Zhang, Yong-Ping Zhang, Xiao-Lu Li, Yi Xie, Shui-Yan Wu, Xin-Ran Chu, Gen Li, Di Wu, Yan-Ling Chen, Juan-Juan Yu, Si-qi Jia, Chen-xi Feng, Yuan-Yuan Tian, Zhi-Heng Li, Jing Ling, Shao-Yan Hu, Jian Pan

J Exp Clin Cancer Res. 2022; 41: 225. Published online 2022 Jul 16. doi: 10.1186/s13046-022-02428-9

PMCID:: PMC9288051

Abstract Article PDF–11M

Select item 68809272.

Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation

Meng-Meng Zhang, Na Liu, Yuan-Liang Zhang, Bowen Rong, Xiao-Lin Wang, Chun-Hui Xu, Yin-Yin Xie, Shuhong Shen, Jiang Zhu, Stephen D. Nimer, Zhu Chen, Sai-Juan Chen, Robert G. Roeder, Fei Lan, Lan Wang, Qiu-Hua Huang, Xiao-Jian Sun

Leukemia. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Leukemia. 2019 Jul; 33(7): 1822–1827. Published online 2019 Feb 12. doi: 10.1038/s41375-019-0398-8

PMCID:: PMC6880927

Article PDF–583K

Select item 59306863.

LYL1 gene amplification predicts poor survival of patients with uterine corpus endometrial carcinoma: analysis of the Cancer genome atlas data

Se Ik Kim, Ji Won Lee, Nara Lee, Maria Lee, Hee Seung Kim, Hyun Hoon Chung, Jae-Weon Kim, Noh Hyun Park, Yong-Sang Song, Jeong-Sun Seo

BMC Cancer. 2018; 18: 494. Published online 2018 May 2. doi: 10.1186/s12885-018-4429-z

PMCID:: PMC5930686

Abstract Article PDF–2.4M

Select item 29370314.

LYL1 Degradation by the Proteasome Is Directed by a N-Terminal PEST Rich Site in a Phosphorylation-Independent Manner

Georgi L. Lukov, Margaret A. Goodell

PLoS One. 2010; 5(9): e12692. Published online 2010 Sep 10. doi: 10.1371/journal.pone.0012692

PMCID:: PMC2937031

Abstract Article PDF–394K

Select item 95863295.

LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML

Qian Chen, Murat A. Cevher, Qi Jiang, Saisai Wang, Xiaojian Sun, Robert G. Roeder, Mo Chen

Proc Natl Acad Sci U S A. 2022 Oct 18; 119(42): e2213718119. Published online 2022 Oct 10. doi: 10.1073/pnas.2213718119

PMCID:: PMC9586329

Abstract Article PDF–1.8M

Select item 2312286.

Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells.

A Miyamoto, X Cui, L Naumovski, M L Cleary

Mol Cell Biol. 1996 May; 16(5): 2394–2401. doi: 10.1128/mcb.16.5.2394

PMCID:: PMC231228

Summary PDF–321K

Select item 531467.

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia.

Y Xia, L Brown, C Y Yang, J T Tsan, M J Siciliano, R Espinosa, III, M M Le Beau, R J Baer

Proc Natl Acad Sci U S A. 1991 Dec 15; 88(24): 11416–11420. doi: 10.1073/pnas.88.24.11416

PMCID:: PMC53146

Summary Page Browse PDF–1.3M

Select item 37325358.

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis

Xiao-Jian Sun, Zhanxin Wang, Lan Wang, Yanwen Jiang, Nils Kost, T. David Soong, Wei-Yi Chen, Zhanyun Tang, Tomoyoshi Nakadai, Olivier Elemento, Wolfgang Fischle, Ari Melnick, Dinshaw J. Patel, Stephen D. Nimer, Robert G. Roeder

Nature. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nature. 2013 Aug 1; 500(7460): 93–97. Published online 2013 Jun 30. doi: 10.1038/nature12287

PMCID:: PMC3732535

Abstract Article PDF–1.3M

Select item 3954229.

Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia.

I Wadman, J Li, R O Bash, A Forster, H Osada, T H Rabbitts, R Baer

EMBO J. 1994 Oct 17; 13(20): 4831–4839. doi: 10.1002/j.1460-2075.1994.tb06809.x

PMCID:: PMC395422

Summary Page Browse PDF–1.8M

Select item 270089810.

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

Xin Hu, Xingguo Li, Kristell Valverde, Xueqi Fu, Constance Noguchi, Yi Qiu, Suming Huang

Proc Natl Acad Sci U S A. 2009 Jun 23; 106(25): 10141–10146. Published online 2009 Jun 3. doi: 10.1073/pnas.0900437106

PMCID:: PMC2700898

Abstract Article PDF–530K

Select item 467383411.

Control of developmentally primed erythroid genes by combinatorial co-repressor actions

Ralph Stadhouders, Alba Cico, Tharshana Stephen, Supat Thongjuea, Petros Kolovos, H. Irem Baymaz, Xiao Yu, Jeroen Demmers, Karel Bezstarosti, Alex Maas, Vilma Barroca, Christel Kockx, Zeliha Ozgur, Wilfred van Ijcken, Marie-Laure Arcangeli, Charlotte Andrieu-Soler, Boris Lenhard, Frank Grosveld, Eric Soler

Nat Commun. 2015; 6: 8893. Published online 2015 Nov 23. doi: 10.1038/ncomms9893

PMCID:: PMC4673834

Abstract Article PDF–2.7M

Select item 307268212.

TIF1γ controls erythroid cell fate by regulating transcription elongation

Xiaoying Bai, Jonghwan Kim, Zhongan Yang, Michael J. Jurynec, Thomas E. Akie, Joseph Lee, Jocelyn LeBlanc, Anna Sessa, Hong Jiang, Anthony DiBiase, Yi Zhou, David J. Grunwald, Shuo Lin, Alan B. Cantor, Stuart H. Orkin, Leonard I. Zon

Cell. Author manuscript; available in PMC 2011 Apr 8.

Published in final edited form as: Cell. 2010 Jul 9; 142(1): 133–143. doi: 10.1016/j.cell.2010.05.028

PMCID:: PMC3072682

Abstract Article PDF–2.7M

Select item 465716113.

PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion

Anna E. Dart, Gary M. Box, William Court, Madeline E. Gale, John P. Brown, Sarah E. Pinder, Suzanne A. Eccles, Claire M. Wells

J Cell Biol. 2015 Nov 23; 211(4): 863–879. doi: 10.1083/jcb.201501072

PMCID:: PMC4657161

Abstract Article PDF–8.1M

Select item 732206714.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 135612915.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406