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Select item 27488501.

Crystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor Symplekin

Sarah A. Kennedy, Monica L. Frazier, Mindy Steiniger, Ann M. Mast, William F. Marzluff, Matthew R. Redinbo

J Mol Biol. Author manuscript; available in PMC 2010 Sep 11.

Published in final edited form as: J Mol Biol. 2009 Sep 11; 392(1): 115–128. Published online 2009 Jul 1. doi: 10.1016/j.jmb.2009.06.062

PMCID:: PMC2748850

Abstract Article PDF–4.1M

Select item 65448362.

Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription

Seema Irani, Sarah N. Sipe, Wanjie Yang, Nathaniel T. Burkholder, Brian Lin, Kelly Sim, Wendy L. Matthews, Jennifer S. Brodbelt, Yan Zhang

J Biol Chem. 2019 May 24; 294(21): 8592–8605. Published online 2019 Apr 10. doi: 10.1074/jbc.RA119.007697

PMCID:: PMC6544836

Abstract Article PDF–3.5M

Select item 45099313.

In vivo characterization of the Drosophila mRNA 3′ end processing core cleavage complex

Daniel Michalski, Mindy Steiniger

RNA. 2015 Aug; 21(8): 1404–1418. doi: 10.1261/rna.049551.115

PMCID:: PMC4509931

Abstract Article PDF–824K

Select item 42965844.

Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72

Yonghua Luo, S. D. Yogesha, Joe R. Cannon, Wupeng Yan, Andrew D. Ellington, Jennifer S. Brodbelt, Yan Zhang

ACS Chem Biol. Author manuscript; available in PMC 2015 Jan 16.

Published in final edited form as: ACS Chem Biol. 2013 Sep 20; 8(9): 2042–2052. Published online 2013 Jul 23. doi: 10.1021/cb400229c

PMCID:: PMC4296584

Abstract Article PDF–1.2M

Select item 53929875.

Drosophila melanogaster retrotransposon and inverted repeat-derived endogenous siRNAs are differentially processed in distinct cellular locations

Andrew W. Harrington, Michael R. McKain, Daniel Michalski, Kaylyn M. Bauer, Joshua M. Daugherty, Mindy Steiniger

BMC Genomics. 2017; 18: 304. Published online 2017 Apr 17. doi: 10.1186/s12864-017-3692-8

PMCID:: PMC5392987

Abstract Article PDF–1.4M

Select item 59610796.

Protein composition of catalytically active U7-dependent processing complexes assembled on histone pre-mRNA containing biotin and a photo-cleavable linker

Aleksandra Skrajna, Xiao-cui Yang, Michał Dadlez, William F Marzluff, Zbigniew Dominski

Nucleic Acids Res. 2018 May 18; 46(9): 4752–4770. Published online 2018 Feb 26. doi: 10.1093/nar/gky133

PMCID:: PMC5961079

Abstract Article PDF–3.0M

Select item 54358667.

U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem–loop binding protein

Aleksandra Skrajna, Xiao-cui Yang, Katarzyna Bucholc, Jun Zhang, Traci M. Tanaka Hall, Michał Dadlez, William F. Marzluff, Zbigniew Dominski

RNA. 2017 Jun; 23(6): 938–951. doi: 10.1261/rna.060806.117

PMCID:: PMC5435866

Abstract Article PDF–1.2M

Select item 35032408.

A core complex of CPSF73, CPSF100 and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs

Kelly D. Sullivan, Mindy Steiniger, William F. Marzluff

Mol Cell. Author manuscript; available in PMC 2012 Nov 21.

Published in final edited form as: Mol Cell. 2009 May 15; 34(3): 322–332. doi: 10.1016/j.molcel.2009.04.024

PMCID:: PMC3503240

Abstract Article PDF–1.6M

Select item 28198249.

FLASH, a pro-apoptotic protein involved in activation of caspase-8 is essential for 3′ end processing of histone pre-mRNAs

Xiao-cui Yang, Brandon D. Burch, Yan Yan, William F. Marzluff, Zbigniew Dominski

Mol Cell. Author manuscript; available in PMC 2010 Oct 23.

Published in final edited form as: Mol Cell. 2009 Oct 23; 36(2): 267. doi: 10.1016/j.molcel.2009.08.016

PMCID:: PMC2819824

Abstract Article PDF–3.1M

Select item 852217010.

Use of circular RNAs as markers of readthrough transcription to identify factors regulating cleavage/polyadenylation events

Dongming Liang, Deirdre C. Tatomer, Jeremy E. Wilusz

Methods. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Methods. 2021 Dec; 196: 121–128. Published online 2021 Apr 18. doi: 10.1016/j.ymeth.2021.04.012

PMCID:: PMC8522170

Abstract Article PDF–1.1M

Select item 461527911.

Drosophila Symplekin localizes dynamically to the histone locus body and tricellular junctions

Deirdre C Tatomer, Lindsay F Rizzardi, Kaitlin P Curry, Alison M Witkowski, William F Marzluff, Robert J Duronio

Nucleus. 2014; 5(6): 613–625. Published online 2014 Dec 10. doi: 10.4161/19491034.2014.990860

PMCID:: PMC4615279

Abstract Article PDF–1.1M

Select item 1073017412.

Histone locus bodies: a paradigm for how nuclear biomolecular condensates control cell cycle regulated gene expression

Mark S. Geisler, James P. Kemp, Jr., Robert J. Duronio

Nucleus. 2023; 14(1): 2293604. Published online 2023 Dec 14. doi: 10.1080/19491034.2023.2293604

PMCID:: PMC10730174

Abstract Article PDF–1.0M

Select item 593464413.

Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module

Todd R Albrecht, Sergey P Shevtsov, Yixuan Wu, Lauren G Mascibroda, Natoya J Peart, Kai-Lieh Huang, Iain A Sawyer, Liang Tong, Miroslav Dundr, Eric J Wagner

Nucleic Acids Res. 2018 May 4; 46(8): 4241–4255. Published online 2018 Feb 20. doi: 10.1093/nar/gky100

PMCID:: PMC5934644

Abstract Article PDF–9.0M

Select item 551924114.

Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body

Robert J. Duronio, William F. Marzluff

RNA Biol. 2017; 14(6): 726–738. Published online 2017 Jan 6. doi: 10.1080/15476286.2016.1265198

PMCID:: PMC5519241

Abstract Article PDF–752K

Select item 872803415.

A Drosophila RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migration

Nirupama Kotian, Katie M Troike, Kristen N Curran, Justin D Lathia, Jocelyn A McDonald

G3 (Bethesda) 2022 Jan; 12(1): jkab356. Published online 2021 Oct 11. doi: 10.1093/g3journal/jkab356

PMCID:: PMC8728034

Abstract Article PDF–867K

Select item 388466916.

3′-End processing of histone pre-mRNAs in Drosophila: U7 snRNP is associated with FLASH and polyadenylation factors

Ivan Sabath, Aleksandra Skrajna, Xiao-cui Yang, Michał Dadlez, William F. Marzluff, Zbigniew Dominski

RNA. 2013 Dec; 19(12): 1726–1744. doi: 10.1261/rna.040360.113

PMCID:: PMC3884669

Abstract Article PDF–1.1M

Select item 289170317.

Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia

Andrés Dekanty, Nuria M. Romero, Agustina P. Bertolin, María G. Thomas, Claudia C. Leishman, Joel I. Perez-Perri, Graciela L. Boccaccio, Pablo Wappner

PLoS Genet. 2010 Jun; 6(6): e1000994. Published online 2010 Jun 24. doi: 10.1371/journal.pgen.1000994