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Select item 95865681.

Targeting firing rate neuronal homeostasis can prevent seizures

Fred Mulroe, Wei-Hsiang Lin, Connie Mackenzie-Gray Scott, Najat Aourz, Yuen Ngan Fan, Graham Coutts, R. Ryley Parrish, Ilse Smolders, Andrew Trevelyan, Robert C. Wykes, Stuart Allan, Sally Freeman, Richard A. Baines

Dis Model Mech. 2022 Oct 1; 15(10): dmm049703. Published online 2022 Oct 10. doi: 10.1242/dmm.049703

PMCID:: PMC9586568

Abstract Article

Select item 71820662.

Pumilio Regulates Sleep Homeostasis in Response to Chronic Sleep Deprivation in Drosophila melanogaster

Luis A. De Jesús-Olmo, Norma Rodríguez, Marcelo Francia, Jonathan Alemán-Rios, Carlos J. Pacheco-Agosto, Joselyn Ortega-Torres, Richard Nieves, Nicolás Fuenzalida-Uribe, Alfredo Ghezzi, José L. Agosto

Front Neurosci. 2020; 14: 319. Published online 2020 Apr 17. doi: 10.3389/fnins.2020.00319

PMCID:: PMC7182066

Abstract Article PDF–3.5M

Select item 44139853.

Dynamic regulation of mRNA decay during neural development

Dana A Burow, Maxine C Umeh-Garcia, Marie B True, Crystal D Bakhaj, David H Ardell, Michael D Cleary

Neural Dev. 2015; 10: 11. Published online 2015 Apr 21. doi: 10.1186/s13064-015-0038-6

PMCID:: PMC4413985

Abstract Article PDF–1.6M

Select item 28741614.

Predicting in vivo binding sites of RNA-binding proteins using mRNA secondary structure

Xiao Li, Gerald Quon, Howard D. Lipshitz, Quaid Morris

RNA. 2010 Jun; 16(6): 1096–1107. doi: 10.1261/rna.2017210

PMCID:: PMC2874161

Abstract Article PDF–1.0M

Select item 14621615.

The Drosophila melanogaster translational repressor pumilio regulates neuronal excitability.

Brett A Schweers, Karina J Walters, Michael Stern

Genetics. 2002 Jul; 161(3): 1177–1185. doi: 10.1093/genetics/161.3.1177

PMCID:: PMC1462161

Summary PDF–201K

Select item 107030966.

A Pumilio Activity Sensor Reveals Bag-of-Marbles Inhibition of Pum Activity in the Drosophila Ovary

Wijeong Jang, Changsoo Kim

Dev Reprod. 2023 Apr; 27(1): 39–46. Published online 2023 Mar 31. doi: 10.12717/DR.2023.27.1.39

PMCID:: PMC10703096

Abstract Article PDF–1.4M

Select item 63924607.

Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover

Wi S. Lai, Rene M. Arvola, Aaron C. Goldstrohm, Perry J. Blackshear

Methods. Author manuscript; available in PMC 2020 Feb 15.

Published in final edited form as: Methods. 2019 Feb 15; 155: 77–87. Published online 2019 Jan 6. doi: 10.1016/j.ymeth.2019.01.003

PMCID:: PMC6392460

Abstract Article PDF–687K

Select item 53851608.

Integrated analysis of RNA-binding protein complexes using in vitro selection and high-throughput sequencing and sequence specificity landscapes (SEQRS)

Tzu-Fang Lou, Chase A Weidmann, Jordan Killingsworth, Traci M Tanaka Hall, Aaron C Goldstrohm, Zachary T Campbell

Methods. Author manuscript; available in PMC 2018 Apr 15.

Published in final edited form as: Methods. 2017 Apr 15; 118-119: 171–181. Published online 2016 Oct 8. doi: 10.1016/j.ymeth.2016.10.001

PMCID:: PMC5385160

Abstract Article PDF–608K

Select item 28475089.

Regulation of Synaptic Pumilio Function by an Aggregation-Prone Domain

Anna M. Salazar, Edward J. Silverman, Kaushiki P. Menon, Kai Zinn

J Neurosci. 2010 Jan 13; 30(2): 515–522. doi: 10.1523/JNEUROSCI.2523-09.2010

PMCID:: PMC2847508

Abstract Article PDF–1.4M

Select item 268551010.

Co-occupancy of two Pumilio molecules on a single hunchback NRE

Yogesh K. Gupta, Tammy H. Lee, Thomas A. Edwards, Carlos R. Escalante, Lyudmila Y. Kadyrova, Robin P. Wharton, Aneel K. Aggarwal

RNA. 2009 Jun; 15(6): 1029–1035. doi: 10.1261/rna.1327609

PMCID:: PMC2685510

Abstract Article PDF–603K

Select item 242313511.

Ribonomic Analysis of Human Pum1 Reveals cis-trans Conservation across Species despite Evolution of Diverse mRNA Target Sets

Adam R. Morris, Neelanjan Mukherjee, Jack D. Keene

Mol Cell Biol. 2008 Jun; 28(12): 4093–4103. Published online 2008 Apr 14. doi: 10.1128/MCB.00155-08

PMCID:: PMC2423135

Abstract Article PDF–784K

Select item 146074812.

The Drosophila pumilio gene encodes two functional protein isoforms that play multiple roles in germline development, gonadogenesis, oogenesis and embryogenesis.

M Parisi, H Lin

Genetics. 1999 Sep; 153(1): 235–250. doi: 10.1093/genetics/153.1.235

PMCID:: PMC1460748

Summary PDF–645K

Select item 136958313.

The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins.

P D Zamore, J R Williamson, R Lehmann

RNA. 1997 Dec; 3(12): 1421–1433.

PMCID:: PMC1369583

Summary PDF–6.3M

Select item 21814414.

Model of the Brain Tumor–Pumilio translation repressor complex

Thomas A. Edwards, Brian D. Wilkinson, Robin P. Wharton, Aneel K. Aggarwal

Genes Dev. 2003 Oct 15; 17(20): 2508–2513. doi: 10.1101/gad.1119403

PMCID:: PMC218144

Abstract Article PDF–329K

Select item 894824415.

Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay

Fátima Cairrão, Cristiana C. Santos, Adrien Le Thomas, Scot Marsters, Avi Ashkenazi, Pedro M. Domingos

Nat Commun. 2022; 13: 1587. Published online 2022 Mar 24. doi: 10.1038/s41467-022-29105-x

PMCID:: PMC8948244

Abstract Article PDF–3.0M

Select item 667468016.

Cellular Excitability and the Regulation of Functional Neuronal Identity: From Gene Expression to Neuromodulation

David J. Schulz, Richard A. Baines, Chris M. Hempel, Lingjun Li, Birgit Liss, Hiroaki Misonou

J Neurosci. 2006 Oct 11; 26(41): 10362–10367. doi: 10.1523/JNEUROSCI.3194-06.2006

PMCID:: PMC6674680

Article PDF–359K

Select item 578522617.

Combinatorial control of messenger RNAs by Pumilio, Nanos and Brain Tumor Proteins

René M. Arvola, Chase A. Weidmann, Traci M. Tanaka Hall, Aaron C. Goldstrohm

RNA Biol. 2017; 14(11): 1445–1456. Published online 2017 Apr 17. doi: 10.1080/15476286.2017.1306168

PMCID:: PMC5785226

Abstract Article PDF–933K

Select item 446096018.

Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition

John D Laver, Xiao Li, Debashish Ray, Kate B Cook, Noah A Hahn, Syed Nabeel-Shah, Mariana Kekis, Hua Luo, Alexander J Marsolais, Karen YY Fung, Timothy R Hughes, J Timothy Westwood, Sachdev S Sidhu, Quaid Morris, Howard D Lipshitz, Craig A Smibert

Genome Biol. 2015; 16(1): 94. Published online 2015 May 12. doi: 10.1186/s13059-015-0659-4

PMCID:: PMC4460960

Abstract Article PDF–1.9M

Select item 5873419.

Poly(A)-independent regulation of maternal hunchback translation in the Drosophila embryo

Daniel Chagnovich, Ruth Lehmann

Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20): 11359–11364. Published online 2001 Sep 18. doi: 10.1073/pnas.201284398

PMCID:: PMC58734

Abstract Article PDF–206K

Select item 842121620.

Structure and dynamics of the quaternary hunchback mRNA translation repression complex

Jakub Macošek, Bernd Simon, Johanna-Barbara Linse, Pravin Kumar Ankush Jagtap, Sophie L Winter, Jaelle Foot, Karine Lapouge, Kathryn Perez, Mandy Rettel, Miloš T Ivanović, Pawel Masiewicz, Brice Murciano, Mikhail M Savitski, Inga Loedige, Jochen S Hub, Frank Gabel, Janosch Hennig

Nucleic Acids Res. 2021 Sep 7; 49(15): 8866–8885. Published online 2021 Jul 30. doi: 10.1093/nar/gkab635