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Items: 1 to 20 of 686

1.
Biochemical characterization of the Drosophila insulin receptor kinase and longevity-associated mutants
Harini Krishnan, Sultan Ahmed, Stevan R. Hubbard, W. Todd Miller
FASEB J. Author manuscript; available in PMC 2024 Jul 29.
Published in final edited form as: FASEB J. 2024 Jan; 38(1): e23355. doi: 10.1096/fj.202301948R
PMCID:
PMC11284340
AbstractArticlePDF–2.2M
2.
Mechanisms of Action of Potentilla discolor Bunge in Type 2 Diabetes Mellitus Based on Network Pharmacology and Experimental Verification in Drosophila
Yinghong Li, Fanwu Wu, Jianbo Zhang, Ye Xu, Hong Chang, Yueyue Yu, Chunhua Jiang, Xiujuan Gao, Huijuan Liu, Zhen Chen, Chenxi Wu, Ji-An Li
Drug Des Devel Ther. 2024; 18: 747–766. Published online 2024 Mar 11. doi: 10.2147/DDDT.S439876
PMCID:
PMC10941989
AbstractArticlePDF–16M
3.
Long-range repression by ecdysone receptor on complex enhancers of the insulin receptor gene
Katie D. Thompson, Will Suber, Rachel Nicholas, David N. Arnosti
Fly (Austin) 2023; 17(1): 2242238. Published online 2023 Aug 24. doi: 10.1080/19336934.2023.2242238
PMCID:
PMC10461493
AbstractArticlePDF–3.8M
4.
Reduced Insulin Signaling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster
Nikolett Dravecz, Tommy Shaw, Isabella Davies, Casey Brown, Lewis Ormerod, Gin Vu, Tyler Walker, Taran Taank, Alan D. Shirras, Susan J. Broughton
Front Aging Neurosci. 2022; 14: 893444. Published online 2022 Jul 5. doi: 10.3389/fnagi.2022.893444
Correction in:
Front Aging Neurosci. 2023; 15: 1307495.
PMCID:
PMC9294736
AbstractArticlePDF–8.0M
5.
Sanghuang Tongxie Formula Ameliorates Insulin Resistance in Drosophila Through Regulating PI3K/Akt Signaling
Xuqing Cao, Xiaojin La, Biwei Zhang, Zhigang Wang, Yinghong Li, Yanping Bo, Hong Chang, Xiujuan Gao, Chunyu Tian, Chenxi Wu, Ji-an Li
Front Pharmacol. 2022; 13: 874180. Published online 2022 Jun 6. doi: 10.3389/fphar.2022.874180
PMCID:
PMC9207506
AbstractArticlePDF–3.1M
6.
Drosophila insulin receptor regulates diabetes-induced mechanical nociceptive hypersensitivity
Harika Dabbara, Arielle Schultz, Seol Hee Im
MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000456. Published online 2021 Sep 16. doi: 10.17912/micropub.biology.000456
PMCID:
PMC8449261
AbstractArticlePDF–226K
7.
Aging modulated by the Drosophila insulin receptor through distinct structure-defined mechanisms
Rochele Yamamoto, Michael Palmer, Helen Koski, Noelle Curtis-Joseph, Marc Tatar
Genetics. 2021 Feb; 217(2): iyaa037. Published online 2021 Jan 5. doi: 10.1093/genetics/iyaa037
PMCID:
PMC8045697
AbstractArticlePDF–1.4M
8.
The Effect of Inulin on Lifespan, Related Gene Expression and Gut Microbiota in InRp5545/TM3 Mutant Drosophila melanogaster: A Preliminary Study
Yuling Dong, Hao Sun, Weichao Yang, Shuang Ma, Beibei Du, Hui Xu
Nutrients. 2019 Mar; 11(3): 636. Published online 2019 Mar 15. doi: 10.3390/nu11030636
PMCID:
PMC6470987
AbstractArticlePDF–3.0M
9.
An Inversion Supergene in Drosophila Underpins Latitudinal Clines in Survival Traits
ESRA DURMAZ, CLARE BENSON, MARTIN KAPUN, PAUL SCHMIDT, THOMAS FLATT
J Evol Biol. Author manuscript; available in PMC 2019 Sep 1.
Published in final edited form as: J Evol Biol. 2018 Sep; 31(9): 1354–1364. Published online 2018 Jun 28. doi: 10.1111/jeb.13310
PMCID:
PMC6179442
AbstractArticlePDF–535K
10.
Complex cis-regulatory landscape of the insulin receptor gene underlies the broad expression of a central signaling regulator
Yiliang Wei, Rewatee H. Gokhale, Anne Sonnenschein, Kelly Mone't Montgomery, Andrew Ingersoll, David N. Arnosti
Development. 2016 Oct 1; 143(19): 3591–3603. doi: 10.1242/dev.138073
PMCID:
PMC5087611
AbstractArticle
11.
A highly pleiotropic amino acid polymorphism in the Drosophila insulin receptor contributes to life-history adaptation
Annalise B. Paaby, Alan O. Bergland, Emily L. Behrman, Paul S. Schmidt
Evolution. Author manuscript; available in PMC 2016 Oct 25.
Published in final edited form as: Evolution. 2014 Dec; 68(12): 3395–3409. Published online 2014 Nov 20. doi: 10.1111/evo.12546
PMCID:
PMC5079517
AbstractArticlePDF–1.3M
12.
Glucose modulates Drosophila longevity and immunity independent of the microbiota
Anthony Galenza, Jaclyn Hutchinson, Shelagh D. Campbell, Bart Hazes, Edan Foley
Biol Open. 2016 Feb 15; 5(2): 165–173. Published online 2016 Jan 21. doi: 10.1242/bio.015016
PMCID:
PMC4823985
AbstractArticlePDF–593K
13.
Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila
M Gorczyca, C Augart, V Budnik
J Neurosci. 1993 Sep 1; 13(9): 3692–3704. doi: 10.1523/JNEUROSCI.13-09-03692.1993
PMCID:
PMC4661178
AbstractPDF–3.1M
14.
Feeding regulates sex pheromone attraction and courtship in Drosophila females
Sébastien Lebreton, Federica Trona, Felipe Borrero-Echeverry, Florian Bilz, Veit Grabe, Paul G. Becher, Mikael A. Carlsson, Dick R. Nässel, Bill S. Hansson, Silke Sachse, Peter Witzgall
Sci Rep. 2015; 5: 13132. Published online 2015 Aug 10. doi: 10.1038/srep13132
PMCID:
PMC4530334
AbstractArticlePDF–1.1M
15.
Transgenerational Inheritance of Diet-Induced Genome Rearrangements in Drosophila
John C. Aldrich, Keith A. Maggert
PLoS Genet. 2015 Apr; 11(4): e1005148. Published online 2015 Apr 17. doi: 10.1371/journal.pgen.1005148
PMCID:
PMC4401788
AbstractArticlePDF–1.9M
16.
Development of a Drosophila melanogaster spliceosensor system for in vivo high-throughput screening in myotonic dystrophy type 1
Irma García-Alcover, Jordi Colonques-Bellmunt, Raquel Garijo, José R. Tormo, Rubén Artero, Mari Carmen Álvarez-Abril, Arturo López Castel, Manuel Pérez-Alonso
Dis Model Mech. 2014 Nov; 7(11): 1297–1306. Published online 2014 Sep 19. doi: 10.1242/dmm.016592
PMCID:
PMC4213733
AbstractArticle
17.
Insulin signalling underlies both plasticity and divergence of a reproductive trait in Drosophila
Delbert A. Green, II, Cassandra G. Extavour
Proc Biol Sci. 2014 Mar 22; 281(1779): 20132673. doi: 10.1098/rspb.2013.2673
PMCID:
PMC3924071
AbstractArticlePDF–781K
18.
Amino acid imbalance explains extension of lifespan by dietary restriction in Drosophila
Richard C. Grandison, Matthew D.W. Piper, Linda Partridge
Nature. Author manuscript; available in PMC 2010 Jun 24.
Published in final edited form as: Nature. 2009 Dec 24; 462(7276): 1061–1064. Published online 2009 Dec 2. doi: 10.1038/nature08619
PMCID:
PMC2798000
AbstractArticlePDF–750K
19.
Structure and ligand specificity of the Drosophila melanogaster insulin receptor.
R Fernandez-Almonacid, O M Rosen
Mol Cell Biol. 1987 Aug; 7(8): 2718–2727. doi: 10.1128/mcb.7.8.2718
PMCID:
PMC367888
SummaryPage BrowsePDF–2.8M
20.
Tissue localization of Drosophila melanogaster insulin receptor transcripts during development.
R S Garofalo, O M Rosen
Mol Cell Biol. 1988 Apr; 8(4): 1638–1647. doi: 10.1128/mcb.8.4.1638
PMCID:
PMC363323
SummaryPage BrowsePDF–3.3M

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