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Select item 71404621.

The Drosophila RNA Helicase Belle (DDX3) Non-Autonomously Suppresses Germline Tumorigenesis Via Regulation of a Specific mRNA Set

Alexei A. Kotov, Baira K. Godneeva, Oxana M. Olenkina, Vladimir E. Adashev, Mikhail V. Trostnikov, Ludmila V. Olenina

Cells. 2020 Mar; 9(3): 550. Published online 2020 Feb 26. doi: 10.3390/cells9030550

PMCID:: PMC7140462

Abstract Article PDF–3.6M

Select item 32529512.

The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together

Ganesh Ramnath Pathare, István Nagy, Stefan Bohn, Pia Unverdorben, Agnes Hubert, Roman Körner, Stephan Nickell, Keren Lasker, Andrej Sali, Tomohiro Tamura, Taiki Nishioka, Friedrich Förster, Wolfgang Baumeister, Andreas Bracher

Proc Natl Acad Sci U S A. 2012 Jan 3; 109(1): 149-154. Published online 2011 Dec 20. doi: 10.1073/pnas.1117648108

PMCID:: PMC3252951

Abstract Article PDF–1.8M

Select item 106700643.

Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

Sentiljana Gumeni, Maria Lamprou, Zoi Evangelakou, Maria S. Manola, Ioannis P. Trougakos

Cells. 2023 Nov; 12(22): 2650. Published online 2023 Nov 18. doi: 10.3390/cells12222650

PMCID:: PMC10670064

Abstract Article PDF–2.1M

Select item 69969434.

CHIP modulates APP‐induced autophagy‐dependent pathological symptoms in Drosophila

Luming Zhuang, Fei Peng, Yuanyuan Huang, Wenzhe Li, Jiuhong Huang, Yunqiang Chu, Pu Ren, Ying Sun, Yan Zhang, Elleen Xue, Xiaowei Guo, Xiafeng Shen, Lei Xue

Aging Cell. 2020 Feb; 19(2): e13070. Published online 2019 Nov 28. doi: 10.1111/acel.13070

PMCID:: PMC6996943

Abstract Article PDF–2.6M

Select item 94093195.

Comparative Ubiquitome Analysis Reveals Deubiquitinating Effects Induced by Wolbachia Infection in Drosophila melanogaster

Qiong Zong, Bin Mao, Hua-Bao Zhang, Bing Wang, Wen-Juan Yu, Zhi-Wei Wang, Yu-Feng Wang

Int J Mol Sci. 2022 Aug; 23(16): 9459. Published online 2022 Aug 21. doi: 10.3390/ijms23169459

PMCID:: PMC9409319

Abstract Article PDF–3.4M

Select item 73693546.

Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila

Iván Fernández-Cruz, Iván Sánchez-Díaz, Verónica Narváez-Padilla, Enrique Reynaud

IBRO Rep. 2020 Dec; 9: 65–77. Published online 2020 Jul 11. doi: 10.1016/j.ibror.2020.07.001

PMCID:: PMC7369354

Abstract Article PDF–2.8M

Select item 40504287.

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress

Eleni N. Tsakiri, Gerasimos P. Sykiotis, Issidora S. Papassideri, Vassilis G. Gorgoulis, Dirk Bohmann, Ioannis P. Trougakos

FASEB J. 2013 Jun; 27(6): 2407–2420. doi: 10.1096/fj.12-221408

PMCID:: PMC4050428

Abstract Article

Select item 57365858.

Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events

Eleni N. Tsakiri, Evangelos Terpos, Eleni-Dimitra Papanagnou, Efstathios Kastritis, Vincent Brieudes, Maria Halabalaki, Tina Bagratuni, Bogdan I. Florea, Herman S. Overkleeft, Luca Scorrano, Alexios-Leandros Skaltsounis, Meletios A. Dimopoulos, Ioannis P. Trougakos

Sci Rep. 2017; 7: 17802. Published online 2017 Dec 19. doi: 10.1038/s41598-017-17596-4

PMCID:: PMC5736585

Abstract Article PDF–3.0M

Select item 12769289.

Zn²⁺-induced reversible dissociation of subunit Rpn10/p54 of the Drosophila 26 S proteasome

Petra Kiss, Áron Szabó, Éva Hunyadi-Gulyás, Katalin F. Medzihradszky, Zoltán Lipinszki, Margit Pál, Andor Udvardy

Biochem J. 2005 Oct 15; 391(Pt 2): 301–310. Prepublished online 2005 Jun 10. Published online 2005 Oct 10. doi: 10.1042/BJ20050523

PMCID:: PMC1276928

Abstract Article PDF–670K

Select item 122269010.

Assembly of the Drosophila 26 S proteasome is accompanied by extensive subunit rearrangements.

Eva Kurucz, István Andó, Máté Sümegi, Harald Hölzl, Barbara Kapelari, Wolfgang Baumeister, Andor Udvardy

Biochem J. 2002 Jul 15; 365(Pt 2): 527–536. doi: 10.1042/BJ20011520

PMCID:: PMC1222690

Summary PDF–383K

Select item 218557611.

The Regulatory Complex of Drosophila melanogaster 26s Proteasomes: Subunit Composition and Localization of a Deubiquitylating Enzyme

Harald Hölzl, Barbara Kapelari, Josef Kellermann, Erika Seemüller, Máté Sümegi, Andor Udvardy, Ohad Medalia, Joseph Sperling, Shirley A. Müller, Andreas Engel, Wolfgang Baumeister

J Cell Biol. 2000 Jul 10; 150(1): 119–130. doi: 10.1083/jcb.150.1.119

PMCID:: PMC2185576

Abstract Article PDF–322K

Select item 271549212.

Insights into the molecular architecture of the 26S proteasome

Stephan Nickell, Florian Beck, Sjors H. W. Scheres, Andreas Korinek, Friedrich Förster, Keren Lasker, Oana Mihalache, Na Sun, István Nagy, Andrej Sali, Jürgen M. Plitzko, Jose-Maria Carazo, Matthias Mann, Wolfgang Baumeister

Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29): 11943–11947. Published online 2009 Jul 6. doi: 10.1073/pnas.0905081106

PMCID:: PMC2715492

Abstract Article PDF–1.1M

Select item 370081413.

Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila

Péter Lőw, Ágnes Varga, Karolina Pircs, Péter Nagy, Zsuzsanna Szatmári, Miklós Sass, Gábor Juhász

BMC Cell Biol. 2013; 14: 29. Published online 2013 Jun 25. doi: 10.1186/1471-2121-14-29

PMCID:: PMC3700814

Abstract Article PDF–2.3M

Select item 355434114.

Identification of factors that function in Drosophila salivary gland cell death during development using proteomics

C K McPhee, B M Balgley, C Nelson, J H Hill, Y Batlevi, X Fang, C S Lee, E H Baehrecke

Cell Death Differ. 2013 Feb; 20(2): 218–225. Published online 2012 Aug 31. doi: 10.1038/cdd.2012.110

PMCID:: PMC3554341

Abstract Article PDF–1.6M

Select item 778725815.

Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila

Stanley Walls, Soda Diop, Ryan Birse, Lisa Elmen, Zhuohui Gan, Sreehari Kalvakuri, Santiago Pineda, Curran Reddy, Erika Taylor, Bosco Trinh, Georg Vogler, Rachel Zarndt, Andrew McCulloch, Peter Lee, Sharmila Bhattacharya, Rolf Bodmer, Karen Ocorr

Cell Rep. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108445. Published online 2020 Nov 25. doi: 10.1016/j.celrep.2020.108445

PMCID:: PMC7787258

Abstract Article PDF–1.5M

Select item 327719016.

Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy

Eri Sakata, Stefan Bohn, Oana Mihalache, Petra Kiss, Florian Beck, Istvan Nagy, Stephan Nickell, Keiji Tanaka, Yasushi Saeki, Friedrich Förster, Wolfgang Baumeister

Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5): 1479-1484. Published online 2012 Jan 3. doi: 10.1073/pnas.1119394109

PMCID:: PMC3277190

Abstract Article PDF–1.1M

Select item 1020640717.

A global genetic interaction network by single-cell imaging and machine learning

Florian Heigwer, Christian Scheeder, Josephine Bageritz, Schayan Yousefian, Benedikt Rauscher, Christina Laufer, Sergi Beneyto-Calabuig, Maja Christina Funk, Vera Peters, Maria Boulougouri, Jana Bilanovic, Thilo Miersch, Barbara Schmitt, Claudia Blass, Fillip Port, Michael Boutros

Cell Syst. 2023 May 17; 14(5): 346–362.e6. doi: 10.1016/j.cels.2023.03.003

PMCID:: PMC10206407

Abstract Article

Select item 114061918.

Identification and Characterization of a Drosophila Proteasome Regulatory Network

Josefin Lundgren, Patrick Masson, Zahra Mirzaei, Patrick Young

Mol Cell Biol. 2005 Jun; 25(11): 4662–4675. doi: 10.1128/MCB.25.11.4662-4675.2005

PMCID:: PMC1140619

Abstract Article PDF–820K

Select item 1021319919.

RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models

Xiaobo Zhang, Yunliang Zhai, Dandan Zhang, Chang Che, Yayun Zhang, Quan Li, Xue Zhang, Lingrui Zhao

Heliyon. 2023 May; 9(5): e16143. Published online 2023 May 19. doi: 10.1016/j.heliyon.2023.e16143

PMCID:: PMC10213199

Abstract Article PDF–5.2M

Select item 675092620.

Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Jia Zhou, Lingna Xu, Xiuying Duan, Wei Liu, Xiaocui Zhao, Xi Wang, Weina Shang, Xuefei Fang, Huan Yang, Lijun Jia, Jian Bai, Jiayao Zhao, Liquan Wang, Chao Tong

Sci Adv. 2019 Sep; 5(9): eaax0365. Published online 2019 Sep 18. doi: 10.1126/sciadv.aax0365