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Select item 79678301.

Drosophila melanogaster as a model to study virulence and azole treatment of the emerging pathogen Candida auris

Sebastian Wurster, Ashwini Bandi, Nicholas D Beyda, Nathaniel D Albert, Nitya M Raman, Isaam I Raad, Dimitrios P Kontoyiannis

J Antimicrob Chemother. 2019 Jul; 74(7): 1904–1910. Published online 2019 Apr 9. doi: 10.1093/jac/dkz100

PMCID:: PMC7967830

Abstract Article PDF–421K

Select item 73271762.

Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds

Sebastian Wurster, Alexander M. Tatara, Nathaniel D. Albert, Ashraf S. Ibrahim, Joseph Heitman, Soo Chan Lee, Amol C. Shetty, Carrie McCracken, Karen T. Graf, Antonios G. Mikos, Vincent M. Bruno, Dimitrios P. Kontoyiannis

mBio. 2020 May-Jun; 11(3): e01414-20. Published online 2020 Jun 30. doi: 10.1128/mBio.01414-20

PMCID:: PMC7327176

Abstract Article PDF–2.9M

Select item 70758503.

A survey of TIR domain sequence and structure divergence

Vladimir Y. Toshchakov, Andrew F. Neuwald

Immunogenetics. 2020; 72(3): 181–203. Published online 2020 Jan 30. doi: 10.1007/s00251-020-01157-7

Correction in:: Immunogenetics. 2022; 74(2): 269.

PMCID:: PMC7075850

Abstract Article PDF–5.3M

Select item 58723244.

Experimental In Vivo Models of Candidiasis

Esther Segal, Michael Frenkel

J Fungi (Basel) 2018 Mar; 4(1): 21. Published online 2018 Feb 6. doi: 10.3390/jof4010021

PMCID:: PMC5872324

Abstract Article PDF–559K

Select item 53597255.

Paradoxical effect to caspofungin in Candida species does not confer survival advantage in a Drosophila model of candidiasis

Régis A Zanette, Dimitrios P Kontoyiannis

Virulence. 2013 Aug 15; 4(6): 497–498. Published online 2013 Jun 26. doi: 10.4161/viru.25523

PMCID:: PMC5359725

Article PDF–295K

Select item 44497286.

Candida albicans Cas5, a Regulator of Cell Wall Integrity, Is Required for Virulence in Murine and Toll Mutant Fly Models

Georgios Chamilos, Clarissa J. Nobile, Vincent M. Bruno, Russell E. Lewis, Aaron P. Mitchell, Dimitrios P. Kontoyiannis

J Infect Dis. Author manuscript; available in PMC 2015 May 30.

Published in final edited form as: J Infect Dis. 2009 Jul 1; 200(1): 152–157. doi: 10.1086/599363

PMCID:: PMC4449728

Abstract Article PDF–447K

Select item 37103387.

Pre-exposure of Candida species to cytarabine and daunorubicin does not affect their in vitro antifungal susceptibility and virulence in flies

Régis A. Zanette, Dimitrios P Kontoyiannis

Virulence. 2013 May 15; 4(4): 344–346. Published online 2013 Apr 23. doi: 10.4161/viru.24387

PMCID:: PMC3710338

Article PDF–247K

Select item 36274108.

Liesegang-like patterns of Toll crystals grown in gel

Monique Gangloff, Abel Moreno, Nicholas J. Gay

J Appl Crystallogr. 2013 Apr 1; 46(Pt 2): 337–345. Published online 2013 Feb 14. doi: 10.1107/S0021889812051606

PMCID:: PMC3627410

Abstract Article PDF–1.1M

Select item 36237159.

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

Erwin Berthier, Fang Yun Lim, Qing Deng, Chun-Jun Guo, Dimitrios P. Kontoyiannis, Clay C. C. Wang, Julie Rindy, David J. Beebe, Anna Huttenlocher, Nancy P. Keller

PLoS Pathog. 2013 Apr; 9(4): e1003289. Published online 2013 Apr 11. doi: 10.1371/journal.ppat.1003289

PMCID:: PMC3623715

Abstract Article PDF–2.6M

Select item 354242810.

Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor

Monique Gangloff, Christopher J. Arnot, Miranda Lewis, Nicholas J. Gay

Structure. 2013 Jan 8; 21(1): 143–153. doi: 10.1016/j.str.2012.11.003

PMCID:: PMC3542428

Abstract Article PDF–1.7M

Select item 321572511.

Wild-Type Drosophila melanogaster as a Model Host to Analyze Nitrogen Source Dependent Virulence of Candida albicans

Monica M. Davis, Francisco J. Alvarez, Kicki Ryman, Åsa A. Holm, Per O. Ljungdahl, Ylva Engström

PLoS One. 2011; 6(11): e27434. Published online 2011 Nov 14. doi: 10.1371/journal.pone.0027434

PMCID:: PMC3215725

Abstract Article PDF–869K

Select item 307335812.

The growing promise of Toll-deficient Drosophila melanogaster as a model for studying Aspergillus pathogenesis and treatment

Michail S Lionakis, Dimitrios P Kontoyiannis

Virulence. 2010 Nov-Dec; 1(6): 488–499. Published online 2010 Nov 1. doi: 10.4161/viru.1.6.13311

PMCID:: PMC3073358

Abstract Article PDF–19M

Select item 280734813.

A novel, noncanonical mechanism of cytoplasmic polyadenylation operates in Drosophila embryogenesis

Olga Coll, Ana Villalba, Giovanni Bussotti, Cedric Notredame, Fátima Gebauer

Genes Dev. 2010 Jan 15; 24(2): 129–134. doi: 10.1101/gad.568610

PMCID:: PMC2807348

Abstract Article PDF–305K

Select item 120333014.

Zygotic Expression and Activity of the Drosophila Toll Gene, a Gene Required Maternally for Embryonic Dorsal-Ventral Pattern Formation

S. Gerttula, Y. Jin, K. V. Anderson

Genetics. 1988 May; 119(1): 123–133. doi: 10.1093/genetics/119.1.123

PMCID:: PMC1203330

Summary PDF–6.6M

Select item 55221215.

The Drosophila membrane receptor Toll can function to promote cellular adhesion.

F J Keith, N J Gay

EMBO J. 1990 Dec; 9(13): 4299–4306. doi: 10.1002/j.1460-2075.1990.tb07878.x

PMCID:: PMC552212

Summary Page Browse PDF–2.2M

Select item 909185916.

Pre-copulatory reproductive behaviours are preserved in Drosophila melanogaster infected with bacteria

Saloni Rose, Esteban J. Beckwith, Charlotte Burmester, Robin C. May, Marc S. Dionne, Carolina Rezaval

Proc Biol Sci. May 11, 2022; 289(1974): 20220492. Published online May 11, 2022. doi: 10.1098/rspb.2022.0492

PMCID:: PMC9091859

Abstract Article PDF–1.3M

Select item 767459817.

Improved cardiac contraction imaging in live Drosophila embryos

Hayley Milner, Scott J. Nowak

MethodsX. 2020; 7: 101130. Published online 2020 Nov 5. doi: 10.1016/j.mex.2020.101130

PMCID:: PMC7674598

Abstract Article PDF–955K

Select item 678265718.

A Single Growth Cone is Capable of Integrating Simultaneously Presented and Functionally Distinct Molecular Cues during Target Recognition

Demian Rose, Akira Chiba

J Neurosci. 1999 Jun 15; 19(12): 4899–4906. doi: 10.1523/JNEUROSCI.19-12-04899.1999

PMCID:: PMC6782657

Abstract Article PDF–904K

Select item 540807619.

Drosophila melanogaster as a High-Throughput Model for Host–Microbiota Interactions

Mark Trinder, Brendan A. Daisley, Josh S. Dube, Gregor Reid

Front Microbiol. 2017; 8: 751. Published online 2017 Apr 28. doi: 10.3389/fmicb.2017.00751

PMCID:: PMC5408076

Abstract Article PDF–4.1M

Select item 464679220.

Drosophila Dicer-2 has an RNA interference–independent function that modulates Toll immune signaling

Zhaowei Wang, Di Wu, Yongxiang Liu, Xiaoling Xia, Wanyun Gong, Yang Qiu, Jie Yang, Ya Zheng, Jingjing Li, Yu-Feng Wang, Ye Xiang, Yuanyang Hu, Xi Zhou

Sci Adv. 2015 Oct; 1(9): e1500228. Published online 2015 Oct 16. doi: 10.1126/sciadv.1500228