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Select item 98935081.

Endoplasmic reticulum-associated protein degradation contributes to Toll innate immune defense in Drosophila melanogaster

Yangyang Zhu, Lei Liu, Chuchu Zhang, Chao Zhang, Tingting Han, Renjie Duan, Yiheng Jin, Huimin Guo, Kan She, Yihua Xiao, Akira Goto, Qingshuang Cai, Shanming Ji

Front Immunol. 2022; 13: 1099637. Published online 2023 Jan 19. doi: 10.3389/fimmu.2022.1099637

PMCID:: PMC9893508

Abstract Article PDF–7.0M

Select item 109071662.

RACK1 and IRE1 participate in the translational quality control of amyloid precursor protein in Drosophila models of Alzheimer’s disease

Yu Li, Dongyue Liu, Xuejing Zhang, Suman Rimal, Bingwei Lu, Shuangxi Li

J Biol Chem. 2024 Mar; 300(3): 105719. Published online 2024 Feb 2. doi: 10.1016/j.jbc.2024.105719

PMCID:: PMC10907166

Abstract Article PDF–4.0M

Select item 17823733.

Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase ‘Synoviolin'

Satoshi Yamasaki, Naoko Yagishita, Takeshi Sasaki, Minako Nakazawa, Yukihiro Kato, Tadayuki Yamadera, Eunkyung Bae, Sayumi Toriyama, Rie Ikeda, Lei Zhang, Kazuko Fujitani, Eunkyung Yoo, Kaneyuki Tsuchimochi, Tomohiko Ohta, Natsumi Araya, Hidetoshi Fujita, Satoko Aratani, Katsumi Eguchi, Setsuro Komiya, Ikuro Maruyama, Nobuyo Higashi, Mitsuru Sato, Haruki Senoo, Takahiro Ochi, Shigeyuki Yokoyama, Tetsuya Amano, Jaeseob Kim, Steffen Gay, Akiyoshi Fukamizu, Kusuki Nishioka, Keiji Tanaka, Toshihiro Nakajima

EMBO J. 2007 Jan 10; 26(1): 113–122. Published online 2006 Dec 14. doi: 10.1038/sj.emboj.7601490

PMCID:: PMC1782373

Abstract Article PDF–313K

Select item 58320654.

highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models

Huai-Wei Huang, Brian Brown, Jaehoon Chung, Pedro M. Domingos, Hyung Don Ryoo

Cell Rep. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Cell Rep. 2018 Feb 6; 22(6): 1384–1391. doi: 10.1016/j.celrep.2018.01.032

PMCID:: PMC5832065

Abstract Article PDF–1.4M

Select item 30333805.

Pathogenic VCP/TER94 Alleles Are Dominant Actives and Contribute to Neurodegeneration by Altering Cellular ATP Level in a Drosophila IBMPFD Model

Ya-Chu Chang, Wan-Tzu Hung, Yun-Chin Chang, Henry C. Chang, Chia-Lin Wu, Ann-Shyn Chiang, George R. Jackson, Tzu-Kang Sang

PLoS Genet. 2011 Feb; 7(2): e1001288. Published online 2011 Feb 3. doi: 10.1371/journal.pgen.1001288

PMCID:: PMC3033380

Abstract Article PDF–12M

Select item 27498436.

Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation

Min-Ji Kang, Hyung Don Ryoo

Proc Natl Acad Sci U S A. 2009 Oct 6; 106(40): 17043–17048. Published online 2009 Sep 23. doi: 10.1073/pnas.0905566106

PMCID:: PMC2749843

Abstract Article PDF–1.6M

Select item 41482197.

Integration of UPR^ER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

Lifen Wang, Xiankun Zeng, Hyung Don Ryoo, Heinrich Jasper

PLoS Genet. 2014 Aug; 10(8): e1004568. Published online 2014 Aug 28. doi: 10.1371/journal.pgen.1004568

PMCID:: PMC4148219

Abstract Article PDF–6.0M

Select item 41777478.

Derlin-1 Regulates Mutant VCP-Linked Pathogenesis and Endoplasmic Reticulum Stress-Induced Apoptosis

Cyong-Jhih Liang, Ya-Chu Chang, Henry C. Chang, Chung-Kang Wang, Yu-Chien Hung, Ying-Er Lin, Chia-Ching Chan, Chun-Hong Chen, Hui-Yun Chang, Tzu-Kang Sang

PLoS Genet. 2014 Sep; 10(9): e1004675. Published online 2014 Sep 25. doi: 10.1371/journal.pgen.1004675

PMCID:: PMC4177747

Abstract Article PDF–10M

Select item 33194949.

Cdk5 and Mekk1 mediate a Pro-Apoptotic Signaling Response to Endoplasmic Reticulum Stress in a Drosophila Model of Autosomal Dominant Retinitis Pigmentosa

Min-Ji Kang, Jaehoon Chung, Hyung Don Ryoo

Nat Cell Biol. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Nat Cell Biol. 2012 Apr; 14(4): 409–415. Published online 2012 Mar 4. doi: 10.1038/ncb2447

PMCID:: PMC3319494

Abstract Article PDF–780K

Select item 256737010.

Metabolomic Signatures of Inbreeding at Benign and Stressful Temperatures in Drosophila melanogaster

Kamilla Sofie Pedersen, Torsten Nygaard Kristensen, Volker Loeschcke, Bent O. Petersen, Jens Ø. Duus, Niels Chr. Nielsen, Anders Malmendal

Genetics. 2008 Oct; 180(2): 1233–1243. doi: 10.1534/genetics.108.089144

PMCID:: PMC2567370

Abstract Article PDF–847K

Select item 720614411.

ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice

Liangyao Xiong, Lin Zhang, Yeming Yang, Na Li, Wenjia Lai, Fengchao Wang, Xianjun Zhu, Tao Wang

Cell Death Differ. 2020 Feb; 27(2): 646–661. Published online 2019 Jul 1. doi: 10.1038/s41418-019-0378-6

PMCID:: PMC7206144

Abstract Article PDF–3.8M

Select item 479095312.

Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster

Riitta Lindström, Päivi Lindholm, Jukka Kallijärvi, Mari Palgi, Mart Saarma, Tapio I. Heino

PLoS One. 2016; 11(3): e0151550. Published online 2016 Mar 14. doi: 10.1371/journal.pone.0151550

PMCID:: PMC4790953

Abstract Article PDF–8.2M

Select item 669717113.

A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

Liam C. Hunt, Jared Stover, Benard Haugen, Timothy I. Shaw, Yuxin Li, Vishwajeeth R. Pagala, David Finkelstein, Elisabeth R. Barton, Yiping Fan, Myriam Labelle, Junmin Peng, Fabio Demontis

Cell Rep. Author manuscript; available in PMC 2019 Aug 15.

Published in final edited form as: Cell Rep. 2019 Jul 30; 28(5): 1268–1281.e6. doi: 10.1016/j.celrep.2019.06.094