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Select item 98287321.

TMEM41B, a novel ER phospholipid scramblase mediating systemic lipid metabolism: A novel ER phospholipid scramblase

Haoliang Hu, Zhe Chen, Shifang Huang, Chengxiao Fu, Linxi Chen

Acta Biochim Biophys Sin (Shanghai) 2022 Nov; 54(11): 1761–1764. Published online 2022 Nov 8. doi: 10.3724/abbs.2022168

PMCID:: PMC9828732

Article PDF–427K

Select item 79546662.

TMEM41B Is a Pan-flavivirus Host Factor

H.-Heinrich Hoffmann, William M. Schneider, Kathryn Rozen-Gagnon, Linde A. Miles, Felix Schuster, Brandon Razooky, Eliana Jacobson, Xianfang Wu, Soon Yi, Charles M. Rudin, Margaret R. MacDonald, Laura K. McMullan, John T. Poirier, Charles M. Rice

Cell. 2021 Jan 7; 184(1): 133–148.e20. Published online 2020 Dec 9. doi: 10.1016/j.cell.2020.12.005

PMCID:: PMC7954666

Abstract Article PDF–6.3M

Select item 77969003.

Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks

William M. Schneider, Joseph M. Luna, H.-Heinrich Hoffmann, Francisco J. Sánchez-Rivera, Andrew A. Leal, Alison W. Ashbrook, Jérémie Le Pen, Inna Ricardo-Lax, Eleftherios Michailidis, Avery Peace, Ansgar F. Stenzel, Scott W. Lowe, Margaret R. MacDonald, Charles M. Rice, John T. Poirier

Cell. 2021 Jan 7; 184(1): 120–132.e14. Published online 2020 Dec 9. doi: 10.1016/j.cell.2020.12.006

PMCID:: PMC7796900

Abstract Article PDF–12M

Select item 81894964.

TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2

Joseph D. Trimarco, Brook E. Heaton, Ryan R. Chaparian, Kaitlyn N. Burke, Raquel A. Binder, Gregory C. Gray, Clare M. Smith, Vineet D. Menachery, Nicholas S. Heaton

PLoS Pathog. 2021 May; 17(5): e1009599. Published online 2021 May 27. doi: 10.1371/journal.ppat.1009599

PMCID:: PMC8189496

Abstract Article PDF–3.3M

Select item 80771755.

TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine

Yang Emma Li, Yichang Wang, Ximing Du, Tizhong Zhang, Hoi Yin Mak, Sarah E. Hancock, Holly McEwen, Elvis Pandzic, Renee M. Whan, Yvette Celine Aw, Ivan E. Lukmantara, Yiqiong Yuan, Xiuju Dong, Anthony Don, Nigel Turner, Shiqian Qi, Hongyuan Yang

J Cell Biol. 2021 Jun 7; 220(6): e202103105. Published online 2021 Apr 30. doi: 10.1083/jcb.202103105

PMCID:: PMC8077175

Abstract Article PDF–5.0M

Select item 61236636.

TMEM41B is a novel regulator of autophagy and lipid mobilization

Francesca Moretti, Phil Bergman, Stacie Dodgson, David Marcellin, Isabelle Claerr, Jonathan M Goodwin, Rowena DeJesus, Zhao Kang, Christophe Antczak, Damien Begue, Debora Bonenfant, Alexandra Graff, Christel Genoud, John S Reece‐Hoyes, Carsten Russ, Zinger Yang, Gregory R Hoffman, Matthias Mueller, Leon O Murphy, Ramnik J Xavier, Beat Nyfeler

EMBO Rep. 2018 Sep; 19(9): e45889. Published online 2018 Aug 20. doi: 10.15252/embr.201845889

PMCID:: PMC6123663

Abstract Article PDF–6.2M

Select item 90973657.

VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection

Mingming Ji, Meng Li, Long Sun, Hongyu Zhao, Ying Li, Lulu Zhou, Zhenni Yang, Xin Zhao, Wenyan Qu, Hanbing Xue, Ze Zheng, Yiming Li, Hongyu Deng, Yan G. Zhao

J Cell Biol. 2022 Jun 6; 221(6): e202112081. Published online 2022 May 10. doi: 10.1083/jcb.202112081

PMCID:: PMC9097365

Abstract Article PDF–6.0M

Select item 80724088.

A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis

Alireza Ghanbarpour, Diana P. Valverde, Thomas J. Melia, Karin M. Reinisch

Proc Natl Acad Sci U S A. 2021 Apr 20; 118(16): e2101562118. Published online 2021 Apr 13. doi: 10.1073/pnas.2101562118

PMCID:: PMC8072408

Abstract Article PDF–485K

Select item 64595559.

CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor

Christopher J. Shoemaker, Tina Q. Huang, Nicholas R. Weir, Nicole J. Polyakov, Sebastian W. Schultz, Vladimir Denic

PLoS Biol. 2019 Apr; 17(4): e2007044. Published online 2019 Apr 1. doi: 10.1371/journal.pbio.2007044

PMCID:: PMC6459555

Abstract Article PDF–4.4M

Select item 621971810.

Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation

Keigo Morita, Yutaro Hama, Tamaki Izume, Norito Tamura, Toshihide Ueno, Yoshihiro Yamashita, Yuriko Sakamaki, Kaito Mimura, Hideaki Morishita, Wataru Shihoya, Osamu Nureki, Hiroyuki Mano, Noboru Mizushima

J Cell Biol. 2018 Nov 5; 217(11): 3817–3828. doi: 10.1083/jcb.201804132

PMCID:: PMC6219718

Abstract Article PDF–2.8M

Select item 837237711.

circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1

Shuying Shen, Yute Yang, Panyang Shen, Jun Ma, Bin Fang, Qingxin Wang, Kefan Wang, Peihua Shi, Shunwu Fan, Xiangqian Fang

Ann Rheum Dis. 2021 Sep; 80(9): 1209–1219. Published online 2021 May 26. doi: 10.1136/annrheumdis-2021-219969

PMCID:: PMC8372377

Abstract Article PDF–7.8M

Select item 624272712.

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development

Meaghan Van Alstyne, Francesco Lotti, Andrea Dal Mas, Estela Area Gomez, Livio Pellizzoni

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Nov 30.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Nov 30; 506(3): 463–470. Published online 2018 Oct 22. doi: 10.1016/j.bbrc.2018.10.073

PMCID:: PMC6242727

Abstract Article PDF–910K

Select item 760600813.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 773761014.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 729072115.

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux

Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070

PMCID:: PMC7290721

Abstract Article PDF–9.2M

Select item 1064152416.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 952364517.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

Select item 933831318.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 553358519.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Abstract Article PDF–5.9M

Select item 720679320.

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler

Science. Author manuscript; available in PMC 2020 May 8.

Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812

PMCID:: PMC7206793

Abstract Article PDF–2.2M

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