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Select item 56785791.

Clusterin protects neurons against intracellular proteotoxicity

Jenna M. Gregory, Daniel R. Whiten, Rebecca A. Brown, Teresa P. Barros, Janet R. Kumita, Justin J. Yerbury, Sandeep Satapathy, Karina McDade, Colin Smith, Leila M. Luheshi, Christopher M. Dobson, Mark R. Wilson

Acta Neuropathol Commun. 2017; 5: 81. Published online 2017 Nov 7. doi: 10.1186/s40478-017-0481-1

PMCID:: PMC5678579

Abstract Article PDF–4.3M

Select item 64327112.

The unfolded protein response in metazoan development

Sahana Mitra, Hyung Don Ryoo

J Cell Sci. 2019 Mar 1; 132(5): jcs217216. Published online 2019 Feb 15. doi: 10.1242/jcs.217216

PMCID:: PMC6432711

Abstract Article

Select item 54366033.

IRE1α nucleotide sequence cleavage specificity in the unfolded protein response

Juthakorn Poothong, Pattarawut Sopha, Randal J. Kaufman, Witoon Tirasophon

FEBS Lett. Author manuscript; available in PMC 2018 Jan 17.

Published in final edited form as: FEBS Lett. 2017 Jan; 591(2): 406–414. Published online 2017 Jan 17. doi: 10.1002/1873-3468.12546

Correction in:: FEBS Lett. 2018 Aug; 592(15): 2669.

PMCID:: PMC5436603

Abstract Article PDF–1.4M

Select item 41381844.

Ire1 Mediated mRNA Splicing in a C-Terminus Deletion Mutant of Drosophila Xbp1

Dina S. Coelho, Catarina J. Gaspar, Pedro M. Domingos

PLoS One. 2014; 9(8): e105588. Published online 2014 Aug 19. doi: 10.1371/journal.pone.0105588

PMCID:: PMC4138184

Abstract Article PDF–738K

Select item 32502455.

Janet R. Kumita, Linda Helmfors, Jocy Williams, Leila M. Luheshi, Linda Menzer, Mireille Dumoulin, David A. Lomas, Damian C. Crowther, Christopher M. Dobson, Ann-Christin Brorsson

FASEB J. 2012 Jan; 26(1): 192–202. doi: 10.1096/fj.11-185983

PMCID:: PMC3250245

Abstract Article

Select item 30901936.

The ER stress factor XBP1s prevents amyloid-β neurotoxicity

Sergio Casas-Tinto, Yan Zhang, Jonatan Sanchez-Garcia, Melisa Gomez-Velazquez, Diego E. Rincon-Limas, Pedro Fernandez-Funez

Hum Mol Genet. 2011 Jun 1; 20(11): 2144–2160. Published online 2011 Mar 9. doi: 10.1093/hmg/ddr100

PMCID:: PMC3090193

Abstract Article PDF–991K

Select item 100612237.

Inhibition of endoplasmic reticulum stress signaling rescues cytotoxicity of human apolipoprotein-L1 risk variants in Drosophila

Lea Gerstner, Mengmeng Chen, Lina L. Kampf, Julian Milosavljevic, Konrad Lang, Ronen Schneider, Friedhelm Hildebrandt, Martin Helmstädter, Gerd Walz, Tobias Hermle

Kidney Int. Author manuscript; available in PMC 2023 Mar 30.

Published in final edited form as: Kidney Int. 2022 Jun; 101(6): 1216–1231. Published online 2022 Feb 1. doi: 10.1016/j.kint.2021.12.031

PMCID:: PMC10061223

Abstract Article PDF–5.3M

Select item 98935088.

Endoplasmic reticulum-associated protein degradation contributes to Toll innate immune defense in Drosophila melanogaster

Yangyang Zhu, Lei Liu, Chuchu Zhang, Chao Zhang, Tingting Han, Renjie Duan, Yiheng Jin, Huimin Guo, Kan She, Yihua Xiao, Akira Goto, Qingshuang Cai, Shanming Ji

Front Immunol. 2022; 13: 1099637. Published online 2023 Jan 19. doi: 10.3389/fimmu.2022.1099637

PMCID:: PMC9893508

Abstract Article PDF–7.0M

Select item 89482449.

Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay

Fátima Cairrão, Cristiana C. Santos, Adrien Le Thomas, Scot Marsters, Avi Ashkenazi, Pedro M. Domingos

Nat Commun. 2022; 13: 1587. Published online 2022 Mar 24. doi: 10.1038/s41467-022-29105-x

PMCID:: PMC8948244

Abstract Article PDF–3.0M

Select item 836451010.

The Role of Ire1 in Drosophila Eye pigmentation Revealed by an RNase Dead Allele

Sahana Mitra, Hyung Don Ryoo

Dev Biol. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Dev Biol. 2021 Oct; 478: 205–211. Published online 2021 Jul 13. doi: 10.1016/j.ydbio.2021.07.008

PMCID:: PMC8364510

Abstract Article PDF–1.3M

Select item 758389311.

Misfolding of Lysosomal α-Galactosidase a in a Fly Model and Its Alleviation by the Pharmacological Chaperone Migalastat

Hila Braunstein, Maria Papazian, Gali Maor, Jan Lukas, Arndt Rolfs, Mia Horowitz

Int J Mol Sci. 2020 Oct; 21(19): 7397. Published online 2020 Oct 7. doi: 10.3390/ijms21197397

PMCID:: PMC7583893

Abstract Article PDF–4.6M

Select item 494876512.

Serum Amyloid P Component Ameliorates Neurological Damage Caused by Expressing a Lysozyme Variant in the Central Nervous System of Drosophila melanogaster

Linda Helmfors, Liza Bergkvist, Ann-Christin Brorsson

PLoS One. 2016; 11(7): e0159294. Published online 2016 Jul 18. doi: 10.1371/journal.pone.0159294

PMCID:: PMC4948765

Abstract Article PDF–2.5M

Select item 443328213.

A Drosophila Reporter for the Translational Activation of ATF4 Marks Stressed Cells during Development

Kwonyoon Kang, Hyung Don Ryoo, Jung-Eun Park, Jee-Hyun Yoon, Min-Ji Kang

PLoS One. 2015; 10(5): e0126795. Published online 2015 May 15. doi: 10.1371/journal.pone.0126795

PMCID:: PMC4433282

Abstract Article PDF–12M

Select item 401939114.

Aging induced ER stress alters sleep and sleep homeostasis

Marishka K. Brown, May T. Chan, John E. Zimmerman, Allan I. Pack, Nicholas E. Jackson, Nirinjini Naidoo

Neurobiol Aging. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Neurobiol Aging. 2014 Jun; 35(6): 1431–1441. Published online 2013 Dec 14. doi: 10.1016/j.neurobiolaging.2013.12.005

PMCID:: PMC4019391

Abstract Article PDF–4.5M

Select item 373225115.

Expression of Human Gaucher Disease Gene GBA Generates Neurodevelopmental Defects and ER Stress in Drosophila Eye

Takahiro Suzuki, Masami Shimoda, Kumpei Ito, Shuji Hanai, Hidenobu Aizawa, Tomoki Kato, Kazunori Kawasaki, Terumi Yamaguchi, Hyung Don Ryoo, Naoko Goto-Inoue, Mitsutoshi Setou, Shoji Tsuji, Norio Ishida

PLoS One. 2013; 8(8): e69147. Published online 2013 Aug 2. doi: 10.1371/journal.pone.0069147