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Select item 75049261.

Insulin signaling requires glucose to promote lipid anabolism in adipocytes

James R. Krycer, Lake-Ee Quek, Deanne Francis, Armella Zadoorian, Fiona C. Weiss, Kristen C. Cooke, Marin E. Nelson, Alexis Diaz-Vegas, Sean J. Humphrey, Richard Scalzo, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Kevin Huynh, Corey Giles, Bianca Varney, Shilpa R. Nagarajan, Andrew J. Hoy, Tomoyoshi Soga, Peter J. Meikle, Gregory J. Cooney, Daniel J. Fazakerley, David E. James

J Biol Chem. 2020 Sep 18; 295(38): 13250–13266. Published online 2020 Jul 28. doi: 10.1074/jbc.RA120.014907

PMCID:: PMC7504926

Abstract Article PDF–4.0M

Select item 78314832.

Functional Inactivation of DrosophilaGCK Orthologs Causes Genomic Instability and Oxidative Stress in a Fly Model of MODY-2

Elisa Mascolo, Francesco Liguori, Lorenzo Stufera Mecarelli, Noemi Amoroso, Chiara Merigliano, Susanna Amadio, Cinzia Volonté, Roberto Contestabile, Angela Tramonti, Fiammetta Vernì

Int J Mol Sci. 2021 Jan; 22(2): 918. Published online 2021 Jan 18. doi: 10.3390/ijms22020918

PMCID:: PMC7831483

Abstract Article PDF–19M

Select item 17482403.

Flux control and excess capacity in the enzymes of glycolysis and their relationship to flight metabolism in Drosophila melanogaster

Walter F. Eanes, Thomas J. S. Merritt, Jonathan M. Flowers, Seiji Kumagai, Efe Sezgin, Chen-Tseh Zhu

Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51): 19413–19418. Published online 2006 Dec 11. doi: 10.1073/pnas.0607095104

PMCID:: PMC1748240

Abstract Article PDF–394K

Select item 68677114.

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

Gabriela Krejčová, Adéla Danielová, Pavla Nedbalová, Michalina Kazek, Lukáš Strych, Geetanjali Chawla, Jason M Tennessen, Jaroslava Lieskovská, Marek Jindra, Tomáš Doležal, Adam Bajgar

eLife. 2019; 8: e50414. Published online 2019 Oct 14. doi: 10.7554/eLife.50414

PMCID:: PMC6867711

Abstract Article PDF–3.8M

Select item 46147585.

Genetic perturbation of key central metabolic genes extends lifespan in Drosophila and affects response to dietary restriction

Matthew E. Talbert, Brittany Barnett, Robert Hoff, Maria Amella, Kate Kuczynski, Erik Lavington, Spencer Koury, Evgeny Brud, Walter F. Eanes

Proc Biol Sci. 2015 Sep 22; 282(1815): 20151646. doi: 10.1098/rspb.2015.1646

PMCID:: PMC4614758

Abstract Article PDF–790K

Select item 27172056.

Persistent Short-Term Memory Defects Following Sleep Deprivation in a Drosophila Model of Parkinson Disease

Laurent Seugnet, James E. Galvin, Yasuko Suzuki, Laura Gottschalk, Paul J. Shaw

Sleep. 2009 Aug 1; 32(8): 984–992. doi: 10.1093/sleep/32.8.984

PMCID:: PMC2717205

Abstract Article PDF–738K

Select item 46978667.

Nutrient Sensor in the Brain Directs the Action of the Brain-Gut Axis in Drosophila

Monica Dus, Jason Sih-Yu Lai, Keith M. Gunapala, Soohong Min, Timothy D. Tayler, Anne C. Hergarden, Eliot Geraud, Christina M. Joseph, Greg S. B. Suh

Neuron. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Neuron. 2015 Jul 1; 87(1): 139–151. Published online 2015 Jun 11. doi: 10.1016/j.neuron.2015.05.032

PMCID:: PMC4697866

Abstract Article PDF–1.8M

Select item 12063308.

P-Element-Induced Variation in Metabolic Regulation in Drosophila

A. G. Clark, L. Wang, T. Hulleberg

Genetics. 1995 Jan; 139(1): 337–348. doi: 10.1093/genetics/139.1.337

PMCID:: PMC1206330

Summary PDF–1.1M

Select item 14613389.

Contrasting molecular population genetics of four hexokinases in Drosophila melanogaster, D. simulans and D. yakuba.

D D Duvernell, W F Eanes

Genetics. 2000 Nov; 156(3): 1191–1201. doi: 10.1093/genetics/156.3.1191

PMCID:: PMC1461338

Summary PDF–513K

Select item 120809910.

Epistasis in Measured Genotypes: Drosophila P-Element Insertions

A. G. Clark, L. Wang

Genetics. 1997 Sep; 147(1): 157–163. doi: 10.1093/genetics/147.1.157

PMCID:: PMC1208099

Summary PDF–777K

Select item 688455211.

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

Nhan Huynh, Qiuxiang Ou, Pendleton Cox, Roland Lill, Kirst King-Jones

Nat Commun. 2019; 10: 5463. Published online 2019 Nov 29. doi: 10.1038/s41467-019-13237-8

PMCID:: PMC6884552

Abstract Article PDF–3.9M

Select item 477280412.

Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle

Vera Slaninova, Michaela Krafcikova, Raquel Perez-Gomez, Pavel Steffal, Lukas Trantirek, Sarah J. Bray, Alena Krejci

Open Biol. 2016 Feb; 6(2): 150155. Published online 2016 Feb 17. doi: 10.1098/rsob.150155

PMCID:: PMC4772804

Abstract Article PDF–1.7M

Select item 460062313.

Heart-specific Rpd3 downregulation enhances cardiac function and longevity

Zachary A. Kopp, Jo-Lin Hsieh, Andrew Li, William Wang, Dhelni T. Bhatt, Angela Lee, Sae Yeon Kim, David Fan, Veevek Shah, Emaad Siddiqui, Radhika Ragam, Kristen Park, Dev Ardeshna, Kunwoo Park, Rachel Wu, Hardik Parikh, Ayush Parikh, Yuh-Ru Lin, Yongkyu Park

Aging (Albany NY) 2015 Sep; 7(9): 648–660. Published online 2015 Sep 21. doi: 10.18632/aging.100806

PMCID:: PMC4600623

Abstract Article PDF–1.9M

Select item 882470114.

Liam C Hunt, Fabio Demontis

J Gerontol A Biol Sci Med Sci. 2022 Feb; 77(2): 259–267. Published online 2021 Sep 3. doi: 10.1093/gerona/glab260

PMCID:: PMC8824701

Abstract Article PDF–8.5M

Select item 853036315.

Metabolic gene regulation by Drosophila GATA transcription factor Grain

Krista Kokki, Nicole Lamichane, Anni I. Nieminen, Hanna Ruhanen, Jack Morikka, Marius Robciuc, Bohdana M. Rovenko, Essi Havula, Reijo Käkelä, Ville Hietakangas

PLoS Genet. 2021 Oct; 17(10): e1009855. Published online 2021 Oct 11. doi: 10.1371/journal.pgen.1009855

PMCID:: PMC8530363

Abstract Article PDF–5.4M

Select item 146280616.

Mapping determinants of variation in energy metabolism, respiration and flight in Drosophila.

Kristi L Montooth, James H Marden, Andrew G Clark

Genetics. 2003 Oct; 165(2): 623–635. doi: 10.1093/genetics/165.2.623

PMCID:: PMC1462806

Summary PDF–178K

Select item 760462517.

Glycolysis regulates Hedgehog signalling via the plasma membrane potential

Stephanie Spannl, Tomasz Buhl, Ioannis Nellas, Salma A Zeidan, K Venkatesan Iyer, Helena Khaliullina, Carsten Schultz, André Nadler, Natalie A Dye, Suzanne Eaton

EMBO J. 2020 Nov 2; 39(21): e101767. Published online 2020 Oct 6. doi: 10.15252/embj.2019101767

Correction in:: EMBO J. 2021 Apr 1; 40(7): e107925.

PMCID:: PMC7604625

Abstract Article PDF–6.7M

Select item 706461318.

Downregulation of respiratory complex I mediates major signalling changes triggered by TOR activation

Raquel Perez-Gomez, Valentina Magnin, Zorana Mihajlovic, Vera Slaninova, Alena Krejci

Sci Rep. 2020; 10: 4401. Published online 2020 Mar 10. doi: 10.1038/s41598-020-61244-3

PMCID:: PMC7064613

Abstract Article PDF–9.2M

Select item 685781519.

A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila

Yangkyun Oh, Jason Sih-Yu Lai, Holly J. Mills, Hediye Erdjument-Bromage, Benno Giammarinaro, Khalil Saadipour, Justin G. Wang, Farhan Abu, Thomas A. Neubert, Greg S. B. Suh

Nature. Author manuscript; available in PMC 2020 Apr 23.

Published in final edited form as: Nature. 2019 Oct; 574(7779): 559–564. Published online 2019 Oct 23. doi: 10.1038/s41586-019-1675-4

PMCID:: PMC6857815

Abstract Article PDF–4.9M

Select item 318348720.

Molecular population genetics and selection in the glycolytic pathway

Walter F. Eanes

J Exp Biol. 2011 Jan 15; 214(2): 165–171. doi: 10.1242/jeb.046458

PMCID:: PMC3183487

Abstract Article

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