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Select item 111583531.

Nek2 as a novel molecular target for the treatment of breast carcinoma

Nobuyuki Tsunoda, Toshio Kokuryo, Koji Oda, Takeshi Senga, Yukihiro Yokoyama, Masato Nagino, Yuji Nimura, Michinari Hamaguchi

Cancer Sci. 2009 Jan; 100(1): 111–116. Published online 2008 Nov 27. doi: 10.1111/j.1349-7006.2008.01007.x

PMCID:: PMC11158353

Abstract Article PDF–369K

Select item 109305162.

NEK2通过抵抗肝癌细胞衰老促进肝癌进展

雷倩, 夏机良, 冯湘玲, 郭姣姣, 李官成, 周文

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Feb 28; 47(2): 153–164. Chinese. doi: 10.11817/j.issn.1672-7347.2022.210058

PMCID:: PMC10930516

Abstract Article PDF–2.9M

Select item 87603053.

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway

Jianyang Xiang, Wahafu Alafate, Wei Wu, Yichang Wang, Xiaodong Li, Wanfu Xie, Xiaobin Bai, Ruichun Li, Maode Wang, Jia Wang

Cell Death Dis. 2022 Jan; 13(1): 58. Published online 2022 Jan 14. doi: 10.1038/s41419-022-04512-6

PMCID:: PMC8760305

Abstract Article PDF–5.5M

Select item 80797114.

The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells

Yainyrette Rivera-Rivera, Mihaela Marina, Shirley Jusino, Miyoung Lee, Jaleisha Vélez Velázquez, Camille Chardón-Colón, Geraldine Vargas, Jaya Padmanabhan, Srikumar P. Chellappan, Harold I. Saavedra

Sci Rep. 2021; 11: 9016. Published online 2021 Apr 27. doi: 10.1038/s41598-021-88512-0

PMCID:: PMC8079711

Abstract Article PDF–2.0M

Select item 74880405.

Targeting NEK2 impairs oncogenesis and radioresistance via inhibiting the Wnt1/β-catenin signaling pathway in cervical cancer

Tie Xu, Yulan Zeng, Linli Shi, Qin Yang, Yeshan Chen, Gang Wu, Guiling Li, Shuangbing Xu

J Exp Clin Cancer Res. 2020; 39: 183. Published online 2020 Sep 10. doi: 10.1186/s13046-020-01659-y

PMCID:: PMC7488040

Abstract Article PDF–5.6M

Select item 70550016.

Nek2 kinase displaces distal appendages from the mother centriole prior to mitosis

Linda Viol, Shoji Hata, Ana Pastor-Peidro, Annett Neuner, Florian Murke, Patrick Wuchter, Anthony D. Ho, Bernd Giebel, Gislene Pereira

J Cell Biol. 2020 Mar 2; 219(3): e201907136. Published online 2020 Feb 14. doi: 10.1083/jcb.201907136

PMCID:: PMC7055001

Abstract Article PDF–7.2M

Select item 67043667.

High NEK2 confers to poor prognosis and contributes to cisplatin‐based chemotherapy resistance in nasopharyngeal carcinoma

He Xu, Liang Zeng, Yongjun Guan, Xiangling Feng, Yinghong Zhu, Yichen Lu, Chen Shi, Shilian Chen, Jiliang Xia, Jiaojiao Guo, Chunmei Kuang, Wei Li, Fengyan Jin, Wen Zhou

J Cell Biochem. 2019 Mar; 120(3): 3547–3558. Published online 2018 Oct 8. doi: 10.1002/jcb.27632

PMCID:: PMC6704366

Abstract Article PDF–1012K

Select item 65897398.

Wei-Dong Fan, Tao Chen, Peng-Jun Liu

World J Gastroenterol. 2019 Jun 21; 25(23): 2898–2910. Published online 2019 Jun 21. doi: 10.3748/wjg.v25.i23.2898

PMCID:: PMC6589739

Abstract Article PDF–11M

Select item 65560289.

Nek2B activates the wnt pathway and promotes triple-negative breast cancer chemothezrapy-resistance by stabilizing β-catenin

Honghong Shen, Wenpeng Yan, Jinyang Yuan, Ziyue Wang, Chen Wang

J Exp Clin Cancer Res. 2019; 38: 243. Published online 2019 Jun 7. doi: 10.1186/s13046-019-1231-y

PMCID:: PMC6556028

Abstract Article PDF–7.4M

Select item 635827210.

Controlling the dynamics of the Nek2 leucine zipper by engineering of “kinetic” disulphide bonds

Daniel S. Gutmans, Sara B-M Whittaker, Karishma Asiani, R. Andrew Atkinson, Alain Oregioni, Mark Pfuhl

PLoS One. 2019; 14(2): e0210352. Published online 2019 Feb 1. doi: 10.1371/journal.pone.0210352

PMCID:: PMC6358272

Abstract Article PDF–3.5M

Select item 580202411.

NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition

Yi Zhang, Wei Wang, Yifei Wang, Xiaohui Huang, Zhaohui Zhang, Bin Chen, Wenxuan Xie, Shaoqiang Li, Shunli Shen, Baogang Peng

Oncol Rep. 2018 Mar; 39(3): 1023–1033. Published online 2018 Jan 22. doi: 10.3892/or.2018.6224

PMCID:: PMC5802024

Abstract Article PDF–1.1M

Select item 550807512.

NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma

M Hao, R Franqui-Machin, H Xu, J Shaughnessy, Jr, B Barlogie, D Roodman, D E Quelle, S Janz, M H Tomasson, R D Sanderson, L Qiu, I Frech, G Tricot, F Zhan

Leukemia. 2017 Jul; 31(7): 1648–1650. Prepublished online 2017 Apr 12. Published online 2017 Apr 25. doi: 10.1038/leu.2017.115