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Select item 112224261.

NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

Camille R. Simoneau, Pei-Yi Chen, Galen K. Xing, Jennifer M. Hayashi, Irene P. Chen, Mir M. Khalid, Nathan L. Meyers, Taha Y. Taha, Kristoffer E. Leon, Rahul K. Suryawanshi, Maria McCavitt-Malvido, Tal Ashuach, Krystal A. Fontaine, Lauren Rodriguez, Bastian Joehnk, Keith Walcott, Sreelakshmi Vasudevan, Xiaohui Fang, Mazharul Maishan, Shawn Schultz, Jeroen P. Roose, Michael A. Matthay, Anita Sil, Mehrdad Arjomandi, Nir Yosef, Melanie Ott

Sci Rep. 2024; 14: 15351. Published online 2024 Jul 4. doi: 10.1038/s41598-024-66003-2

PMCID:: PMC11222426

Abstract Article PDF–4.0M

Select item 100398602.

IKBA phosphorylation governs human sperm motility through ACC-mediated fatty acid beta-oxidation

Yanquan Li, Youwei Hu, Zhengquan Wang, Tingting Lu, Yiting Yang, Hua Diao, Xiaoguo Zheng, Chong Xie, Ping Zhang, Xuelian Zhang, Yuchuan Zhou

Commun Biol. 2023; 6: 323. Published online 2023 Mar 25. doi: 10.1038/s42003-023-04693-6

PMCID:: PMC10039860

Abstract Article PDF–3.4M

Select item 96020673.

A Novel De Novo NFKBIA Missense Mutation Associated to Ectodermal Dysplasia with Dysgammaglobulinemia

Chai Teng Chear, Bader Abdul Kader El Farran, Marina Sham, Kavetha Ramalingam, Lokman Mohd Noh, Intan Hakimah Ismail, Mei Yee Chiow, Mohd Farid Baharin, Adiratna Mat Ripen, Saharuddin Bin Mohamad

Genes (Basel) 2022 Oct; 13(10): 1900. Published online 2022 Oct 19. doi: 10.3390/genes13101900

PMCID:: PMC9602067

Abstract Article PDF–2.0M

Select item 86365654.

IκBα is required for full transcriptional induction of some NFκB-regulated genes in response to TNF in MCF-7 cells

Minami Ando, Shigeyuki Magi, Masahide Seki, Yutaka Suzuki, Takeya Kasukawa, Diane Lefaudeux, Alexander Hoffmann, Mariko Okada

NPJ Syst Biol Appl. 2021; 7: 42. Published online 2021 Dec 1. doi: 10.1038/s41540-021-00204-7

Correction in:: NPJ Syst Biol Appl. 2022; 8: 26.

PMCID:: PMC8636565

Abstract Article PDF–6.1M

Select item 83449035.

Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4

Laura Marruecos, Joan Bertran, Daniel Álvarez‐Villanueva, María Carmen Mulero, Yolanda Guillén, Luis G Palma, Martin Floor, Anna Vert, Sara Arce‐Gallego, Irene Pecharroman, Laura Batlle, Jordi Villà‐Freixa, Gourisankar Ghosh, Anna Bigas, Lluís Espinosa

EMBO Rep. 2021 Aug 4; 22(8): e52649. Published online 2021 Jul 5. doi: 10.15252/embr.202152649

PMCID:: PMC8344903

Abstract Article PDF–2.0M

Select item 68779816.

Gene Variant in the NF-κB Pathway Inhibitor NFKBIA Distinguishes Patients with Psoriatic Arthritis within the Spectrum of Psoriatic Disease

Pablo Coto-Segura, Eliecer Coto, Leire González-Lara, Belén Alonso, Juan Gómez, Elías Cuesta-Llavona, Rubén Queiro

Biomed Res Int. 2019; 2019: 1030256. Published online 2019 Nov 11. doi: 10.1155/2019/1030256

PMCID:: PMC6877981

Abstract Article PDF–1.0M

Select item 54895717.

Disseminated Mycobacterium malmoense and Salmonella Infections Associated with a Novel Variant in NFKBIA

Emily Staples, Beatriz Morillo-Gutierrez, Jessica Davies, Daniel Petersheim, Michel Massaad, Mary Slatter, Dimitra Dimou, Rainer Doffinger, Scott Hackett, Dinkantha Kumararatne, James Hadfield, Matthew D. Eldridge, Raif S. Geha, Mario Abinun, James E. D. Thaventhiran

J Clin Immunol. 2017; 37(5): 415–418. Published online 2017 Apr 17. doi: 10.1007/s10875-017-0390-x

PMCID:: PMC5489571

Article PDF–864K

Select item 53383968.

Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant

Holly E. Dembinski, Kevin Wismer, Jesse D. Vargas, Gajendra W. Suryawanshi, Nadja Kern, Gerard Kroon, H. Jane Dyson, Alexander Hoffmann, Elizabeth A. Komives

Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): 1916–1921. Published online 2017 Feb 6. doi: 10.1073/pnas.1610192114

PMCID:: PMC5338396

Abstract Article PDF–1.5M

Select item 48236969.

Deletion and low expression of NFKBIA are associated with poor prognosis in lower-grade glioma patients

Gabriela Sarti Kinker, Andrew Maltez Thomas, Vinicius Jardim Carvalho, Felipe Prata Lima, André Fujita

Sci Rep. 2016; 6: 24160. Published online 2016 Apr 7. doi: 10.1038/srep24160

PMCID:: PMC4823696

Abstract Article PDF–1.0M

Select item 472054810.

Severe mycobacterial diseases in a patient with GOF IκBα mutation without EDA

Alison Joanne Lee, Marcela Moncada-Vélez, Capucine Picard, Genevieve Llanora, Chiung-Hui Huang, Laurent Abel, Si Min Chan, Bee-Wah Lee, Jean-Laurent Casanova, Jacinta Bustamante, Lynette Pei-Chi Shek, Stéphanie Boisson-Dupuis

J Clin Immunol. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: J Clin Immunol. 2016 Jan; 36(1): 12–15. Published online 2015 Dec 21. doi: 10.1007/s10875-015-0223-8

Correction in:: J Clin Immunol. 2016 Apr; 36(3): 335.

PMCID:: PMC4720548

Article PDF–982K

Select item 462116511.

Common Polymorphisms in the NFKBIA Gene and Cancer Susceptibility: A Meta-Analysis

Meng Zhang, Junjie Huang, Xiuxiu Tan, Jian Bai, Hao Wang, Yukun Ge, Hu Xiong, Jizhou Shi, Wei Lu, Zhaojie Lv, Chaozhao Liang

Med Sci Monit. 2015; 21: 3186–3196. Published online 2015 Oct 21. doi: 10.12659/MSM.895257

PMCID:: PMC4621165

Abstract Article PDF–707K

Select item 461660212.

Genetic Association Between NFKBIA -881A>G Polymorphism and Cancer Susceptibility

Peiliang Geng, Juanjuan Ou, Jianjun Li, Yunmei Liao, Ning Wang, Rina Sa, Lisha Xiang, Houjie Liang

Medicine (Baltimore) 2015 Aug; 94(31): e1024. Published online 2015 Aug 7. doi: 10.1097/MD.0000000000001024

PMCID:: PMC4616602

Abstract Article PDF–435K

Select item 461004613.

Associations between single nucleotide polymorphisms in the FAS pathway and acute kidney injury

Pavan Bhatraju, Christine Hsu, Paramita Mukherjee, Bradford J. Glavan, Amber Burt, Carmen Mikacenic, Jonathan Himmelfarb, Mark Wurfel

Crit Care. 2015; 19: 368. Published online 2015 Oct 19. doi: 10.1186/s13054-015-1084-5

PMCID:: PMC4610046

Abstract Article PDF–825K

Select item 428255814.

IκΒα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention

Evangelos Pazarentzos, Anne-Laure Mahul-Mellier, Christoph Datler, Wanwisa Chaisaklert, Ming-Shih Hwang, Jan Kroon, Ding Qize, Foy Osborne, Abdullah Al-Rubaish, Amein Al-Ali, Nicholas D Mazarakis, Eric O Aboagye, Stefan Grimm

EMBO J. 2014 Dec 1; 33(23): 2814–2828. Published online 2014 Oct 31. doi: 10.15252/embj.201488183

PMCID:: PMC4282558

Abstract Article PDF–2.3M

Select item 419941615.

Identification of a NFKBIA polymorphism associated with lower NFKBIA protein levels and poor survival outcomes in patients with glioblastoma multiforme

ZHAOHUI ZHAO, XINGMING ZHONG, TINFENG WU, TIANQUAN YANG, GUILIN CHEN, XUESHUN XIE, YONGXIN WEI, MING YE, YOUXIN ZHOU, ZIWEI DU

Int J Mol Med. 2014 Nov; 34(5): 1233–1240. Published online 2014 Sep 12. doi: 10.3892/ijmm.2014.1932

PMCID:: PMC4199416

Abstract Article PDF–830K

Select item 409005216.

Transgenic inhibition of astroglial NF-κB leads to increased axonal sparing and sprouting following spinal cord injury

Roberta Brambilla, Andres Hurtado, Trikaldarshi Persaud, Kim Esham, Damien D. Pearse, Martin Oudega, John R. Bethea

J Neurochem. Author manuscript; available in PMC 2014 Jul 9.

Published in final edited form as: J Neurochem. 2009 Jul; 110(2): 765–778. Published online 2009 May 26. doi: 10.1111/j.1471-4159.2009.06190.x

PMCID:: PMC4090052

Abstract Article PDF–1.0M

Select item 402939217.

Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres

Monica Patanè, Paola Porrati, Elisa Bottega, Sara Morosini, Gabriele Cantini, Vita Girgenti, Ambra Rizzo, Marica Eoli, Bianca Pollo, Francesca L Sciacca, Serena Pellegatta, Gaetano Finocchiaro

Mol Cancer. 2013; 12: 160. Published online 2013 Dec 11. doi: 10.1186/1476-4598-12-160

PMCID:: PMC4029392

Abstract Article PDF–1.3M

Select item 399285518.

Variant in the 3′ Region of the IκBα Gene Associated With Insulin Resistance in Hispanic Americans: The IRAS Family Study

Melissa R. Miller, Weiming Zhang, Scott P. Sibbel, Carl D. Langefeld, Donald W. Bowden, Steven M. Haffner, Richard N. Bergman, Jill M. Norris, Tasha E. Fingerlin

Obesity (Silver Spring) Author manuscript; available in PMC 2014 Apr 21.

Published in final edited form as: Obesity (Silver Spring). 2010 Mar; 18(3): 555–562. Published online 2009 Oct 1. doi: 10.1038/oby.2009.303

PMCID:: PMC3992855

Abstract Article PDF–966K

Select item 383342119.

IκBα Promoter Polymorphisms in Patients with Behçet’s Disease

Yu-Hung Hung, Cheng-Chin Wu, Tsan-Teng Ou, Chia-Hui Lin, Ruei-Nian Li, Yu-Chih Lin, Wen-Chan Tsai, Hong-Wen Liu, Jeng-Hsien Yen

Dis Markers. 2010; 28(1): 55–62. Published online 2010 Feb 17. doi: 10.3233/DMA-2010-0684

PMCID:: PMC3833421

Summary PDF–366K

Select item 382091120.

Long-term Incubation with Proteasome Inhibitors (PIs) Induces IκBα Degradation via the Lysosomal Pathway in an IκB Kinase (IKK)-dependent and IKK-independent Manner

Kyoung-Hee Lee, Jiyeong Jeong, Chul-Gyu Yoo

J Biol Chem. 2013 Nov 8; 288(45): 32777–32786. Published online 2013 Oct 1. doi: 10.1074/jbc.M113.480921

PMCID:: PMC3820911

Abstract Article PDF–1.8M

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