U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from Gene

Items: 1 to 20 of 31

1.
High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype
Ceren Sucularli, Peedikayil Thomas, Hande Kocak, James S. White, Bridget C. O’Connor, Catherine E. Keegan
Gene. Author manuscript; available in PMC 2019 Dec 30.
Published in final edited form as: Gene. 2018 Dec 30; 679: 219–231. Published online 2018 Sep 4. doi: 10.1016/j.gene.2018.09.002
PMCID:
PMC6186184
AbstractArticlePDF–2.5M
2.
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation
Morgan Jones, Gail Osawa, Joshua A. Regal, Daniel N. Weinberg, James Taggart, Hande Kocak, Ann Friedman, David O. Ferguson, Catherine E. Keegan, Ivan Maillard
J Clin Invest. 2014 Jan 2; 124(1): 353–366. Published online 2013 Dec 9. doi: 10.1172/JCI67871
PMCID:
PMC3967656
AbstractArticlePDF–2.5M
3.
Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline
Jacqueline V Graniel, Kamlesh Bisht, Ann Friedman, James White, Eric Perkey, Ashley Vanderbeck, Alina Moroz, Léolène J Carrington, Joshua D Brandstadter, Frederick Allen, Adrienne Niederriter Shami, Peedikayil Thomas, Aniela Crayton, Mariel Manzor, Anna Mychalowych, Jennifer Chase, Saher S Hammoud, Catherine E Keegan, Ivan Maillard, Jayakrishnan Nandakumar
Life Sci Alliance. 2022 Jan; 5(1): e202101208. Published online 2021 Oct 13. doi: 10.26508/lsa.202101208
PMCID:
PMC8548261
AbstractArticlePDF–3.5M
4.
Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres
Peili Gu, Shuting Jia, Taylor Takasugi, Valerie M. Tesmer, Jayakrishnan Nandakumar, Yong Chen, Sandy Chang
Nat Commun. 2021; 12: 5514. Published online 2021 Sep 17. doi: 10.1038/s41467-021-25799-7
PMCID:
PMC8448735
AbstractArticlePDF–8.7M
5.
The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action
Sherilyn Grill, Valerie M. Tesmer, Jayakrishnan Nandakumar
Cell Rep. Author manuscript; available in PMC 2018 Feb 16.
Published in final edited form as: Cell Rep. 2018 Jan 30; 22(5): 1132–1140. doi: 10.1016/j.celrep.2018.01.012
PMCID:
PMC5815312
AbstractArticlePDF–1.3M
6.
TPP1 Is Required for TERT Recruitment, Telomere Elongation during Nuclear Reprogramming, and Normal Skin Development in Mice
Agueda M. Tejera, Martina Stagno d’Alcontres, Maria Thanasoula, Rosa M. Marion, Paula Martinez, Chunyan Liao, Juana M. Flores, Madalena Tarsounas, Maria A. Blasco
Dev Cell. Author manuscript; available in PMC 2013 Apr 22.
Published in final edited form as: Dev Cell. 2010 May 18; 18(5): 775–789. doi: 10.1016/j.devcel.2010.03.011
PMCID:
PMC3631760
AbstractArticlePDF–5.5M
7.
Additive effect of TAp63 deficiency on the adrenocortical dysplasia (acd) phenotype
Bridget C. O’Connor, Erica L. Macke, Catherine E. Keegan
Mamm Genome. Author manuscript; available in PMC 2012 Dec 1.
Published in final edited form as: Mamm Genome. 2011 Dec; 22(11-12): 714–721. Published online 2011 Oct 22. doi: 10.1007/s00335-011-9360-4
PMCID:
PMC3298752
AbstractArticlePDF–640K
8.
Genetic p53 deficiency partially rescues the adrenocortical dysplasia (acd) phenotype at the expense of increased tumorigenesis
Tobias Else, Alessia Trovato, Alex C. Kim, Yipin Wu, David O. Ferguson, Rork D. Kuick, Peter C. Lucas, Gary D. Hammer
Cancer Cell. Author manuscript; available in PMC 2010 Jun 2.
Published in final edited form as: Cancer Cell. 2009 Jun 2; 15(6): 465–476. doi: 10.1016/j.ccr.2009.04.011
PMCID:
PMC2703790
AbstractArticlePDF–2.6M
9.
TPP1 blocks an ATR-mediated resection mechanism at telomeres
Tatsuya Kibe, Michal Zimmermann, Titia de Lange
Mol Cell. Author manuscript; available in PMC 2017 Jan 21.
Published in final edited form as: Mol Cell. 2016 Jan 21; 61(2): 236–246. Published online 2016 Jan 14. doi: 10.1016/j.molcel.2015.12.016
Correction in:
Mol Cell. 2017 Apr 20; 66(2): 300.
PMCID:
PMC4724337
AbstractArticlePDF–2.1M
10.
Mitoribosomal Deregulation Drives Senescence via TPP1-Mediated Telomere Deprotection
Seongki Min, So Mee Kwon, Jiwon Hong, Young-Kyoung Lee, Tae Jun Park, Su Bin Lim, Gyesoon Yoon
Cells. 2022 Jul; 11(13): 2079. Published online 2022 Jun 30. doi: 10.3390/cells11132079
PMCID:
PMC9265344
AbstractArticlePDF–6.4M
11.
TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis
Sherilyn Grill, Shilpa Padmanaban, Ann Friedman, Eric Perkey, Frederick Allen, Valerie M. Tesmer, Jennifer Chase, Rami Khoriaty, Catherine E. Keegan, Ivan Maillard, Jayakrishnan Nandakumar
JCI Insight. 2021 May 10; 6(9): e138059. Published online 2021 May 10. doi: 10.1172/jci.insight.138059
PMCID:
PMC8262337
AbstractArticlePDF–2.7M
12.
ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity
Courtney A. Lovejoy, Kaori Takai, Michael S. Huh, David J. Picketts, Titia de Lange
PLoS Biol. 2020 Jan; 18(1): e3000594. Published online 2020 Jan 2. doi: 10.1371/journal.pbio.3000594
PMCID:
PMC6959610
AbstractArticlePDF–5.0M
13.
Telomere Protection by TPP1 Is Mediated by POT1a and POT1b
Tatsuya Kibe, Gail A. Osawa, Catherine E. Keegan, Titia de Lange
Mol Cell Biol. 2010 Feb; 30(4): 1059–1066. Published online 2009 Dec 7. doi: 10.1128/MCB.01498-09
PMCID:
PMC2815557
AbstractArticlePDF–2.2M
14.
Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection
David Frescas, Titia de Lange
J Biol Chem. 2014 Aug 29; 289(35): 24180–24187. Published online 2014 Jul 23. doi: 10.1074/jbc.M114.592592
PMCID:
PMC4148849
AbstractArticlePDF–2.5M
15.
Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease
Tanveer Ahmad, Isaac K. Sundar, Ana M. Tormos, Chad A. Lerner, Janice Gerloff, Hongwei Yao, Irfan Rahman
Am J Respir Cell Mol Biol. 2017 Jan; 56(1): 38–49. doi: 10.1165/rcmb.2016-0198OC
PMCID:
PMC5248966
AbstractArticlePDF–3.0M
16.
TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1
David Frescas, Titia de Lange
Mol Cell Biol. 2014 Apr; 34(7): 1349–1362. doi: 10.1128/MCB.01052-13
PMCID:
PMC3993560
AbstractArticlePDF–5.2M
17.
OB Fold-containing Protein 1 (OBFC1), a Human Homolog of Yeast Stn1, Associates with TPP1 and Is Implicated in Telomere Length Regulation
Ma Wan, Jun Qin, Zhou Songyang, Dan Liu
J Biol Chem. 2009 Sep 25; 284(39): 26725–26731. Published online 2009 Aug 1. doi: 10.1074/jbc.M109.021105
PMCID:
PMC2785360
AbstractArticlePDF–1.7M
18.
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
Xiaolan Guo, Yibin Deng, Yahong Lin, Wilfredo Cosme-Blanco, Suzanne Chan, Hua He, Guohua Yuan, Eric J Brown, Sandy Chang
EMBO J. 2007 Nov 14; 26(22): 4709–4719. Published online 2007 Oct 18. doi: 10.1038/sj.emboj.7601893
PMCID:
PMC2080807
AbstractArticlePDF–519K
19.
TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling
Michal Zimmermann, Tatsuya Kibe, Shaheen Kabir, Titia de Lange
Genes Dev. 2014 Nov 15; 28(22): 2477–2491. doi: 10.1101/gad.251611.114
PMCID:
PMC4233241
AbstractArticlePDF–1.6M
20.
Telomere protection by TPP1/POT1 requires tethering to TIN2
Kaori K. Takai, Tatsuya Kibe, Jill R. Donigian, David Frescas, Titia de Lange
Mol Cell. Author manuscript; available in PMC 2012 Nov 18.
Published in final edited form as: Mol Cell. 2011 Nov 18; 44(4): 647–659. doi: 10.1016/j.molcel.2011.08.043
Correction in:
Mol Cell. 2017 Jul 6; 67(1): 162.
PMCID:
PMC3222871
AbstractArticlePDF–4.7M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center