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Items: 1 to 20 of 25

1.
The structure-specific endonuclease complex SLX4/XPF regulates Tus/Ter-induced homologous recombination
Rajula Elango, Arvind Panday, Francis P. Lach, Nicholas A. Willis, Kaitlin Nicholson, Erin E. Duffey, Agata Smogorzewska, Ralph Scully
Nat Struct Mol Biol. Author manuscript; available in PMC 2023 Feb 21.
Published in final edited form as: Nat Struct Mol Biol. 2022 Aug; 29(8): 801–812. Published online 2022 Aug 8. doi: 10.1038/s41594-022-00812-9
PMCID:
PMC9941964
AbstractArticlePDF–5.3M
2.
Growth Retardation, Early Death, and DNA Repair Defects in Mice Deficient for the Nucleotide Excision Repair Enzyme XPF
Ming Tian, Reiko Shinkura, Nobuhiko Shinkura, Frederick W. Alt
Mol Cell Biol. 2004 Feb; 24(3): 1200–1205. doi: 10.1128/MCB.24.3.1200-1205.2004
PMCID:
PMC321450
AbstractArticlePDF–365K
3.
Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair
Michael R.G. Hodskinson, Jan Silhan, Gerry P. Crossan, Juan I. Garaycoechea, Shivam Mukherjee, Christopher M. Johnson, Orlando D. Schärer, Ketan J. Patel
Mol Cell. 2014 May 8; 54(3): 472–484. doi: 10.1016/j.molcel.2014.03.014
PMCID:
PMC4017094
AbstractArticle
4.
Cathepsin Cleavage of Sirtuin 1 in Endothelial Progenitor Cells Mediates Stress-Induced Premature Senescence
Jun Chen, Sandhya Xavier, Eliza Moskowitz-Kassai, Robert Chen, Connie Y. Lu, Kyle Sanduski, Aleš Špes, Boris Turk, Michael S. Goligorsky
Am J Pathol. 2012 Mar; 180(3): 973–983. doi: 10.1016/j.ajpath.2011.11.033
PMCID:
PMC3349894
AbstractArticlePDF–2.2M
5.
TRF1 Controls Telomere Length and Mitotic Fidelity in Epithelial Homeostasis
Purificacion Muñoz, Raquel Blanco, Guillermo de Carcer, Stefan Schoeftner, Roberta Benetti, Juana M. Flores, Marcos Malumbres, Maria A. Blasco
Mol Cell Biol. 2009 Mar; 29(6): 1608–1625. Published online 2009 Jan 5. doi: 10.1128/MCB.01339-08
PMCID:
PMC2648247
AbstractArticlePDF–7.9M
6.
ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair
Anwaar Ahmad, Andria Rasile Robinson, Anette Duensing, Ellen van Drunen, H. Berna Beverloo, David B. Weisberg, Paul Hasty, Jan H. J. Hoeijmakers, Laura J. Niedernhofer
Mol Cell Biol. 2008 Aug; 28(16): 5082–5092. Published online 2008 Jun 9. doi: 10.1128/MCB.00293-08
PMCID:
PMC2519706
AbstractArticlePDF–489K
7.
The Structure-Specific Endonuclease Ercc1-Xpf Is Required To Resolve DNA Interstrand Cross-Link-Induced Double-Strand Breaks
Laura J. Niedernhofer, Hanny Odijk, Magda Budzowska, Ellen van Drunen, Alex Maas, Arjan F. Theil, Jan de Wit, N. G. J. Jaspers, H. Berna Beverloo, Jan H. J. Hoeijmakers, Roland Kanaar
Mol Cell Biol. 2004 Jul; 24(13): 5776–5787. doi: 10.1128/MCB.24.13.5776-5787.2004
PMCID:
PMC480908
AbstractArticlePDF–701K
8.
USP45 deubiquitylase controls ERCC1–XPF endonuclease-mediated DNA damage responses
Ana B Perez-Oliva, Christophe Lachaud, Piotr Szyniarowski, Ivan Muñoz, Thomas Macartney, Ian Hickson, John Rouse, Dario R Alessi
EMBO J. 2015 Feb 3; 34(3): 326–343. Published online 2014 Dec 23. doi: 10.15252/embj.201489184
PMCID:
PMC4339120
AbstractArticlePDF–2.7M
9.
Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53
Alejandro P Ugalde, Andrew J Ramsay, Jorge de la Rosa, Ignacio Varela, Guillermo Mariño, Juan Cadiñanos, Jun Lu, José MP Freije, Carlos López-Otín
EMBO J. 2011 Jun 1; 30(11): 2219–2232. Published online 2011 Apr 26. doi: 10.1038/emboj.2011.124
PMCID:
PMC3117645
AbstractArticlePDF–1.8M
10.
siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/− with susceptibility versus C57BL/6-Trp53+/− mice with resistance to mammary tumors
M Böhringer, K Obermeier, N Griner, D Waldraff, E Dickinson, K Eirich, D Schindler, M Hagen, D J Jerry, L Wiesmüller
Oncogene. 2013 Nov 28; 32(48): 5458–5470. Published online 2013 Feb 25. doi: 10.1038/onc.2013.38
PMCID:
PMC3898496
AbstractArticlePDF–1.6M
11.
Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria
Irene Kamileri, Ismene Karakasilioti, Aria Sideri, Theodoros Kosteas, Antonis Tatarakis, Iannis Talianidis, George A. Garinis
Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8): 2995–3000. Published online 2012 Feb 8. doi: 10.1073/pnas.1114941109
PMCID:
PMC3286994
AbstractArticlePDF–725K
12.
Assembly, Verification, and Initial Annotation of the NIA Mouse 7.4K cDNA Clone Set
Vincent VanBuren, Yulan Piao, Dawood B. Dudekula, Yong Qian, Mark G. Carter, Patrick R. Martin, Carole A. Stagg, Uwem C. Bassey, Kazuhiro Aiba, Toshio Hamatani, George J. Kargul, Amber G. Luo, Janet Kelso, Winston Hide, Minoru S.H. Ko
Genome Res. 2002 Dec; 12(12): 1999–2003. doi: 10.1101/gr.633802
PMCID:
PMC187561
AbstractArticlePDF–431K
13.
Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method
Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko
Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501
PMCID:
PMC311119
AbstractArticlePDF–743K
14.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
AbstractArticlePDF–287K
15.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
17.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
18.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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