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Items: 1 to 20 of 70

1.
Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer’s disease, restores synapse integrity and memory in a disease mouse model
Nuria Martin Flores, Marina Podpolny, Faye McLeod, Isaac Workman, Karen Crawford, Dobril Ivanov, Ganna Leonenko, Valentina Escott-Price, Patricia C Salinas
eLife. 2024; 12: RP89453. Published online 2024 Jan 29. doi: 10.7554/eLife.89453
PMCID:
PMC10945611
AbstractArticlePDF–29M
2.
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration
Frank Arnold, Pallavi U Mahaddalkar, Johann M. Kraus, Xiaowei Zhong, Wendy Bergmann, Dharini Srinivasan, Johann Gout, Elodie Roger, Alica K. Beutel, Eugen Zizer, Umesh Tharehalli, Nora Daiss, Ronan Russell, Lukas Perkhofer, Rupert Oellinger, Qiong Lin, Ninel Azoitei, Frank‐Ulrich Weiss, Markus M. Lerch, Stefan Liebau, Sarah‐Fee Katz, André Lechel, Roland Rad, Thomas Seufferlein, Hans A. Kestler, Michael Ott, Amar Deep Sharma, Patrick C. Hermann, Alexander Kleger
Adv Sci (Weinh) 2021 Jul; 8(14): 2100626. Published online 2021 May 13. doi: 10.1002/advs.202100626
PMCID:
PMC8292873
AbstractArticlePDF–28M
3.
DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage
Yang Xu, Derek Nowrangi, Hui Liang, Tian Wang, Lingyan Yu, Tai Lu, Zhengyang Lu, John H. Zhang, Benyan Luo, Jiping Tang
J Neuroinflammation. 2020; 17: 130. Published online 2020 Apr 24. doi: 10.1186/s12974-020-01794-5
PMCID:
PMC7181567
AbstractArticlePDF–2.1M
4.
Dickkopf-3 Causes Neuroprotection by Inducing Vascular Endothelial Growth Factor
Carla Letizia Busceti, Luisa Di Menna, Franca Bianchi, Federica Mastroiacovo, Paola Di Pietro, Anna Traficante, Giovanna Bozza, Christof Niehrs, Giuseppe Battaglia, Valeria Bruno, Francesco Fornai, Massimo Volpe, Speranza Rubattu, Ferdinando Nicoletti
Front Cell Neurosci. 2018; 12: 292. Published online 2018 Sep 11. doi: 10.3389/fncel.2018.00292
PMCID:
PMC6143799
AbstractArticlePDF–1.8M
5.
Dickkopf‐3 Ablation Attenuates the Development of Atherosclerosis in ApoE‐Deficient Mice
Wen‐Lin Cheng, Yang Yang, Xiao‐Jing Zhang, Junhong Guo, Jun Gong, Fu‐Han Gong, Zhi‐Gang She, Zan Huang, Hao Xia, Hongliang Li
J Am Heart Assoc. 2017 Feb; 6(2): e004690. Published online 2017 Feb 20. doi: 10.1161/JAHA.116.004690
PMCID:
PMC5523766
AbstractArticlePDF–3.9M
6.
BAC-Dkk3-EGFP Transgenic Mouse: An In Vivo Analytical Tool for Dkk3 Expression
Yuki Muranishi, Takahisa Furukawa
J Biomed Biotechnol. 2012; 2012: 973140. Published online 2012 Jul 15. doi: 10.1155/2012/973140
PMCID:
PMC3403811
AbstractArticlePDF–5.9M
7.
Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance
Maria Papatriantafyllou, Gerhard Moldenhauer, Julia Ludwig, Anna Tafuri, Natalio Garbi, Gorana Hollmann, Günter Küblbeck, Alexandra Klevenz, Sabine Schmitt, Georg Pougialis, Christof Niehrs, Hermann-Josef Gröne, Gunter J. Hämmerling, Bernd Arnold, Thilo Oelert
Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5): 1631–1636. Published online 2012 Jan 17. doi: 10.1073/pnas.1115980109
PMCID:
PMC3277179
AbstractArticlePDF–875K
8.
Analysis of Dickkopf3 interactions with Wnt signaling receptors
REI E. I. NAKAMURA, ABIGAIL S. HACKAM
Growth Factors. Author manuscript; available in PMC 2010 Oct 6.
Published in final edited form as: Growth Factors. 2010 Aug; 28(4): 232–242. doi: 10.3109/08977191003738832
PMCID:
PMC2950226
AbstractArticlePDF–1.9M
9.
Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina
Rei EI Nakamura, Dale D Hunter, Hyun Yi, William J Brunken, Abigail S Hackam
BMC Cell Biol. 2007; 8: 52. Published online 2007 Dec 19. doi: 10.1186/1471-2121-8-52
PMCID:
PMC2233618
AbstractArticlePDF–1.1M
10.
Generation and Characterization of dickkopf3 Mutant Mice
Ivan del Barco Barrantes, Ana Montero-Pedrazuela, Ana Guadaño-Ferraz, Maria-Jesus Obregon, Raquel Martinez de Mena, Valérie Gailus-Durner, Helmut Fuchs, Tobias J. Franz, Svetoslav Kalaydjiev, Martina Klempt, Sabine Hölter, Birgit Rathkolb, Claudia Reinhard, Gabriella Morreale de Escobar, Juan Bernal, Dirk H. Busch, Wolfgang Wurst, Eckhard Wolf, Holger Schulz, Svetlana Shtrom, Erich Greiner, Martin Hrabé de Angelis, Heiner Westphal, Christof Niehrs
Mol Cell Biol. 2006 Mar; 26(6): 2317–2326. doi: 10.1128/MCB.26.6.2317-2326.2006
PMCID:
PMC1430294
AbstractArticlePDF–364K
11.
DKK3 promotes renal fibrosis by increasing MFF-mediated mitochondrial dysfunction in Wnt/β-catenin pathway-dependent manner
Jianling Song, Yanxia Chen, Yan Chen, Minzi Qiu, Wenliu Xiang, Ben Ke, Xiangdong Fang
Ren Fail. 2024; 46(1): 2343817. Published online 2024 Apr 29. doi: 10.1080/0886022X.2024.2343817
PMCID:
PMC11060011
AbstractArticlePDF–8.9M
12.
Dickkopf-3 attenuates pressure overload-induced cardiac remodelling
Yan Zhang, Yu Liu, Xue-Hai Zhu, Xiao-Dong Zhang, Ding-Sheng Jiang, Zhou-Yan Bian, Xiao-Fei Zhang, Ke Chen, Xiang Wei, Lu Gao, Li-Hua Zhu, Qinglin Yang, Guo-Chang Fan, Wayne B. Lau, Xinliang Ma, Hongliang Li
Cardiovasc Res. 2014 Apr 1; 102(1): 35–45. Published online 2014 Jan 9. doi: 10.1093/cvr/cvu004
PMCID:
PMC6279202
AbstractArticlePDF–1.7M
13.
A Cytokine-Like Protein Dickkopf-Related Protein 3 Is Atheroprotective
Baoqi Yu, Stefan Kiechl, Dan Qi, Xiaocong Wang, Yanting Song, Siegfried Weger, Agnes Mayr, Alexandra Le Bras, Eirini Karamariti, Zhongyi Zhang, Ivan del Barco Barrantes, Christof Niehrs, Georg Schett, Yanhua Hu, Wen Wang, Johann Willeit, Aijuan Qu, Qingbo Xu
Circulation. 2017 Sep 12; 136(11): 1022–1036. Published online 2017 Sep 11. doi: 10.1161/CIRCULATIONAHA.117.027690
PMCID:
PMC5598907
AbstractArticlePDF–1.9M
14.
Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy
D W L Wong, W H Yiu, H J Wu, R X Li, Y Liu, K W Chan, J C K Leung, L Y Y Chan, K N Lai, S C W Tang
Cell Death Dis. 2016 Mar; 7(3): e2155. Published online 2016 Mar 24. doi: 10.1038/cddis.2016.62
PMCID:
PMC4823961
AbstractArticlePDF–5.1M
15.
Dickkopf Homolog 3 (DKK3) Plays a Crucial Role Upstream of WNT/β-CATENIN Signaling for Sertoli Cell Mediated Regulation of Spermatogenesis
Deepika Sharma Das, Neerja Wadhwa, Neetu Kunj, Kanchan Sarda, Bhola Shankar Pradhan, Subeer S. Majumdar
PLoS One. 2013; 8(5): e63603. Published online 2013 May 7. doi: 10.1371/journal.pone.0063603
Correction in:
PLoS One. 2014; 9(1): 10.1371/annotation/a05eeef0-0251-4c4a-bed6-45b022797c74.
PMCID:
PMC3647036
AbstractArticlePDF–5.7M
16.
Binding of Dickkopf-3 to CXCR7 Enhances Vascular Progenitor Cell Migration and Degradable Graft Regeneration
Shirin Issa Bhaloo, Yifan Wu, Alexandra Le Bras, Baoqi Yu, Wenduo Gu, Yao Xie, Jiacheng Deng, Zhihong Wang, Zhongyi Zhang, Deling Kong, Yanhua Hu, Aijuan Qu, Qiang Zhao, Qingbo Xu
Circ Res. 2018 Aug 3; 123(4): 451–466. Published online 2018 Jun 6. doi: 10.1161/CIRCRESAHA.118.312945
PMCID:
PMC6092110
AbstractArticlePDF–12M
17.
Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis
Giuseppina Federico, Michael Meister, Daniel Mathow, Gunnar H. Heine, Gerhard Moldenhauer, Zoran V. Popovic, Viola Nordström, Annette Kopp-Schneider, Thomas Hielscher, Peter J. Nelson, Franz Schaefer, Stefan Porubsky, Danilo Fliser, Bernd Arnold, Hermann-Josef Gröne
JCI Insight. 2016 Jan 21; 1(1): e84916. Published online 2016 Jan 21. doi: 10.1172/jci.insight.84916
PMCID:
PMC5033928
AbstractArticlePDF–5.5M
18.
Dickkopf Homolog 3 Induces Stem Cell Differentiation into Smooth Muscle Lineage via ATF6 Signalling
Xiaocong Wang, Eirini Karamariti, Russell Simpson, Wen Wang, Qingbo Xu
J Biol Chem. 2015 Aug 7; 290(32): 19844–19852. Published online 2015 Jun 23. doi: 10.1074/jbc.M115.641415
PMCID:
PMC4528144
AbstractArticlePDF–1.4M
19.
Cell and matrix response of temporomandibular cartilage to mechanical loading
Achint Utreja, Nathaniel A. Dyment, Sumit Yadav, Max M. Villa, Yingcui Li, Xi Jiang, Ravindra Nanda, David W. Rowe
Osteoarthritis Cartilage. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Osteoarthritis Cartilage. 2016 Feb; 24(2): 335–344. Published online 2015 Sep 8. doi: 10.1016/j.joca.2015.08.010
PMCID:
PMC4757844
AbstractArticlePDF–2.4M
20.
Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma
Liran Zhou, Hongmei Husted, Todd Moore, Mason Lu, Defeng Deng, Yan Liu, Vijaya Ramachandran, Thiruvengadam Arumugam, Christof Niehrs, Huamin Wang, Paul Chiao, Jianhua Ling, Michael A. Curran, Anirban Maitra, Mien-Chie Hung, Jeffrey E. Lee, Craig D. Logsdon, Rosa F. Hwang
Sci Transl Med. Author manuscript; available in PMC 2019 Sep 19.
Published in final edited form as: Sci Transl Med. 2018 Oct 24; 10(464): eaat3487. doi: 10.1126/scitranslmed.aat3487
PMCID:
PMC6752716
AbstractArticlePDF–1.9M

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