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Select item 1249181.

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

Christopher S. Brower, Shigeo Sato, Chieri Tomomori-Sato, Takumi Kamura, Arnim Pause, Robert Stearman, Richard D. Klausner, Sohail Malik, William S. Lane, Irina Sorokina, Robert G. Roeder, Joan Weliky Conaway, Ronald C. Conaway

Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16): 10353–10358. Published online 2002 Jul 29. doi: 10.1073/pnas.162424199

PMCID:: PMC124918

Abstract Article PDF–264K

Select item 35663072.

The SCF–Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator

Michael A. Davis, Elizabeth A. Larimore, Brian M. Fissel, Jherek Swanger, Dylan J. Taatjes, Bruce E. Clurman

Genes Dev. 2013 Jan 15; 27(2): 151–156. doi: 10.1101/gad.207720.112

PMCID:: PMC3566307

Abstract Article PDF–1.2M

Select item 51049373.

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin

Roy Baas, Ayestha Sijm, Hetty A. A. M. van Teeffelen, Robert van Es, Harmjan R. Vos, H. Th. Marc Timmers

J Biol Chem. 2016 Nov 11; 291(46): 24121–24132. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748582

PMCID:: PMC5104937

Abstract Article PDF–4.4M

Select item 10840414.

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

Gerhard Mittler, Elisabeth Kremmer, H. Th. Marc Timmers, Michael Meisterernst

EMBO Rep. 2001 Sep 15; 2(9): 808–813. doi: 10.1093/embo-reports/kve186

PMCID:: PMC1084041

Abstract Article PDF–413K

Select item 41049645.

Subunit architecture and functional modular rearrangements of the transcriptional Mediator complex

Kuang-Lei Tsai, Chieri Tomomori-Sato, Shigeo Sato, Ronald C. Conaway, Joan W. Conaway, Francisco J. Asturias

Cell. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Cell. 2014 Jun 5; 157(6): 1430–1444. Published online 2014 May 29. doi: 10.1016/j.cell.2014.05.015

Correction in:: volume 158 on page 463

PMCID:: PMC4104964

Abstract Article PDF–939K

Select item 28239226.

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

Anna Malovannaya, Yehua Li, Yaroslava Bulynko, Sung Yun Jung, Yi Wang, Rainer B. Lanz, Bert W. O’Malley, Jun Qin

Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2431–2436. Published online 2010 Jan 22. doi: 10.1073/pnas.0912599106

Correction in:: Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13): 6118.

PMCID:: PMC2823922

Abstract Article PDF–566K

Select item 31453257.

Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway

Cell. Author manuscript; available in PMC 2012 Jul 8.

Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005

PMCID:: PMC3145325

Abstract Article PDF–1.9M

Select item 3108768.

Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics

Chun-Hung Lai, Chang-Yuan Chou, Lan-Yang Ch'ang, Chung-Shyan Liu, Wen-chang Lin

Genome Res. 2000 May; 10(5): 703–713. doi: 10.1101/gr.10.5.703

PMCID:: PMC310876

Abstract Article PDF–1.2M

Select item 28971159.

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes

Arnaud R Krebs, Jeroen Demmers, Krishanpal Karmodiya, Nan-Chi Chang, Alice Chien Chang, László Tora

EMBO Rep. 2010 Jul; 11(7): 541–547. Published online 2010 May 28. doi: 10.1038/embor.2010.75

PMCID:: PMC2897115

Abstract Article PDF–433K

Select item 31116310.

Protein–Protein Interaction Panel Using Mouse Full-Length cDNAs

Harukazu Suzuki, Yoshifumi Fukunishi, Ikuko Kagawa, Rintaro Saito, Hiroshi Oda, Toshinori Endo, Shinji Kondo, Hidemasa Bono, Yasushi Okazaki, Yoshihide Hayashizaki

Genome Res. 2001 Oct; 11(10): 1758–1765. doi: 10.1101/gr.180101

PMCID:: PMC311163

Abstract Article PDF–205K

Select item 892305711.

Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava

Cell. Author manuscript; available in PMC 2023 Mar 3.

Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021

PMCID:: PMC8923057

Abstract Article PDF–2.5M

Select item 810809312.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 637572913.

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains

Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras

Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006

PMCID:: PMC6375729

Abstract Article PDF–10M

Select item 438371314.

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Jean-Philippe Lambert, Monika Tucholska, Christopher Go, James D.R. Knight, Anne-Claude Gingras

J Proteomics. Author manuscript; available in PMC 2016 Apr 6.

Published in final edited form as: J Proteomics. 2015 Apr 6; 118: 81–94. Published online 2014 Oct 2. doi: 10.1016/j.jprot.2014.09.011

PMCID:: PMC4383713

Abstract Article PDF–1.4M

Select item 283626715.

An atlas of combinatorial transcriptional regulation in mouse and man

The FANTOM consortium and RIKEN Omics Science Center

Cell. Author manuscript; available in PMC 2011 Mar 5.

Published in final edited form as: Cell. 2010 Mar 5; 140(5): 744–752. doi: 10.1016/j.cell.2010.01.044

Correction in:: volume 141 on page 369

PMCID:: PMC2836267

Abstract Article PDF–2.2M

Select item 977255816.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 642409817.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 835296418.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 586483219.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 742732720.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

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