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Items: 1 to 20 of 61

1.
Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia
Tadashi Kayashima, Kohei Nakata, Kenoki Ohuchida, Junji Ueda, Kengo Shirahane, Hayato Fujita, Lin Cui, Kazuhiro Mizumoto, Masao Tanaka
Cancer Sci. 2011 Jun; 102(6): 1137–1143. Published online 2011 Apr 27. doi: 10.1111/j.1349-7006.2011.01936.x
PMCID:
PMC11158636
AbstractArticlePDF–389K
2.
Genome‐wide loss‐of‐function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus‐integrated hepatoma cells
Makoto Fukuoka, Takahiro Kodama, Kazuhiro Murai, Hayato Hikita, Emi Sometani, Jihyun Sung, Akiyoshi Shimoda, Satoshi Shigeno, Daisuke Motooka, Akira Nishio, Kunimaro Furuta, Tomohide Tatsumi, Kosuke Yusa, Tetsuo Takehara
Cancer Sci. 2024 Mar; 115(3): 859–870. Published online 2024 Jan 29. doi: 10.1111/cas.16070
PMCID:
PMC10920982
AbstractArticlePDF–4.0M
3.
The CC Genotype of Insulin-Induced Gene 2 rs7566605 Is a Protective Factor of Hypercholesteremia Susceptible to Mild Cognitive Impairment, Especially to the Executive Function of Patients with Type 2 Diabetes Mellitus
Haoqiang Zhang, Rong Huang, Sai Tian, Ke An, Wenwen Zhu, Jijing Shi, Wuyou Cao, Shaohua Wang
Biomed Res Int. 2020; 2020: 4935831. Published online 2020 Jun 10. doi: 10.1155/2020/4935831
PMCID:
PMC7303749
AbstractArticlePDF–386K
4.
INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program
Francesca Pirini, Sebastian Rodriguez-Torres, Bola Grace Ayandibu, María Orera-Clemente, Alberto Gonzalez-De La Vega, Fahcina Lawson, Roland J. Thorpe Jr, David Sidransky, Rafael Guerrero-Preston
Mol Med Rep. 2018 Jan; 17(1): 1699–1709. Published online 2017 Nov 14. doi: 10.3892/mmr.2017.8039
PMCID:
PMC5780113
AbstractArticlePDF–1022K
5.
Association of INSIG2 Polymorphism with Overweight and LDL in Children
Anne-Marie Kaulfers, Ranjan Deka, Lawrence Dolan, Lisa J. Martin
PLoS One. 2015; 10(1): e0116340. Published online 2015 Jan 21. doi: 10.1371/journal.pone.0116340
PMCID:
PMC4301876
AbstractArticlePDF–1.4M
6.
INSIG2 variants, dietary patterns, and metabolic risk in Samoa
Ana Baylin, Ranjan Deka, John Tuitele, Satupaitea Viali, Daniel E. Weeks, Stephen T. McGarvey
Eur J Clin Nutr. Author manuscript; available in PMC 2013 Apr 24.
Published in final edited form as: Eur J Clin Nutr. 2013 Jan; 67(1): 101–107. Published online 2012 Sep 12. doi: 10.1038/ejcn.2012.124
PMCID:
PMC3634362
AbstractArticlePDF–434K
7.
The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk
Daniele Campa, Anika Hüsing, James D McKay, Olga Sinilnikova, Ulla Vogel, Anne Tjønneland, Kim Overvad, Jakob Stegger, Françoise Clavel-Chapelon, Nathalie Chabbert-Buffet, Guy Fagherazzi, Antonia Trichopoulou, Dimosthenis Zylis, Erifili Oustoglou, Sabine Rohrmann, Birgit Teucher, Eva Fisher, Heiner Boeing, Giovanna Masala, Vittorio Krogh, Carlotta Sacerdote, Salvatore Panico, Rosario Tumino, N Charlotte Onland-Moret, Carla H van Gils, H Bas Bueno-de-Mesquita, Eiliv Lund, María Dolores Chirlaque, Núria Sala, José Ramon Quirós, Eva Ardanaz, Pilar Amiano, Esther Molina-Montes, Göran Hallmans, Per Lenner, Ruth C Travis, Timothy J Key, Nick Wareham, Kay-Tee Khaw, Sabina Rinaldi, Nadia Slimani, Veronique Chajes, Afshan Siddiq, Elio Riboli, Rudolf Kaaks, Federico Canzian
BMC Cancer. 2010; 10: 563. Published online 2010 Oct 18. doi: 10.1186/1471-2407-10-563
PMCID:
PMC2965729
AbstractArticlePDF–164K
8.
Association of an INSIG2 obesity allele with cardiovascular phenotypes is gender and age dependent
Kimberly A Skelding, Glenn S Gerhard, Helen Vlachos, Faith Selzer, Sheryl F Kelsey, Xin Chu, Robert Erdman, David O Williams, Kevin E Kip
BMC Cardiovasc Disord. 2010; 10: 46. Published online 2010 Sep 29. doi: 10.1186/1471-2261-10-46
PMCID:
PMC2958931
AbstractArticlePDF–216K
9.
INSIG2 SNPS ASSOCIATED WITH OBESITY & GLUCOSE HOMEOSTASIS TRAITS IN HISPANICS: THE IRAS FAMILY STUDY
Matthew E Talbert, Carl D Langefeld, Julie Ziegler, Steven M Haffner, Jill M Norris, Donald W Bowden
Obesity (Silver Spring) Author manuscript; available in PMC 2010 Aug 5.
Published in final edited form as: Obesity (Silver Spring). 2009 Aug; 17(8): 1554–1562. Published online 2009 Apr 9. doi: 10.1038/oby.2009.94
PMCID:
PMC2916685
AbstractArticlePDF–771K
10.
Common INSIG2 polymorphisms are associated with age-related changes in body size and HDL-cholesterol from young adulthood to middle-age
Myriam Fornage, George Papanicolaou, Cora E. Lewis, Eric Boerwinkle, David S. Siscovick
Metabolism. Author manuscript; available in PMC 2011 Aug 1.
Published in final edited form as: Metabolism. 2010 Aug; 59(8): 1084–1091. Published online 2009 Dec 31. doi: 10.1016/j.metabol.2009.11.005
PMCID:
PMC2888786
AbstractArticlePDF–473K
11.
A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans
Ranjan Deka, Ling Xu, Prodipto Pal, Palanitina T Toelupe, Tuiasina S Laumoli, Huifeng Xi, Ge Zhang, Daniel E Weeks, Stephen T McGarvey
BMC Med Genet. 2009; 10: 143. Published online 2009 Dec 22. doi: 10.1186/1471-2350-10-143
PMCID:
PMC2804583
AbstractArticlePDF–322K
12.
Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations
Seongwon Cha, Imhoi Koo, Sun Mi Choi, Byung Lae Park, Kil Soo Kim, Jae-Ryong Kim, Hyoung Doo Shin, Jong Yeol Kim
BMC Med Genet. 2009; 10: 96. Published online 2009 Sep 22. doi: 10.1186/1471-2350-10-96
PMCID:
PMC2759923
AbstractArticlePDF–713K
13.
Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?
Iris M. Heid, Cornelia Huth, Ruth J. F. Loos, Florian Kronenberg, Vera Adamkova, Sonia S. Anand, Kristin Ardlie, Heike Biebermann, Peter Bjerregaard, Heiner Boeing, Claude Bouchard, Marina Ciullo, Jackie A. Cooper, Dolores Corella, Christian Dina, James C. Engert, Eva Fisher, Francesc Francès, Philippe Froguel, Johannes Hebebrand, Robert A. Hegele, Anke Hinney, Margret R. Hoehe, Frank B. Hu, Jaroslav A. Hubacek, Steve E. Humphries, Steven C. Hunt, Thomas Illig, Marjo-Riita Järvelin, Marika Kaakinen, Barbara Kollerits, Heiko Krude, Jitender Kumar, Leslie A. Lange, Birgit Langer, Shengxu Li, Andreas Luchner, Helen N. Lyon, David Meyre, Karen L. Mohlke, Vincent Mooser, Almut Nebel, Thuy Trang Nguyen, Bernhard Paulweber, Louis Perusse, Lu Qi, Tuomo Rankinen, Dieter Rosskopf, Stefan Schreiber, Shantanu Sengupta, Rossella Sorice, Anita Suk, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Henry Völzke, Karani S. Vimaleswaran, Nicholas J. Wareham, Dawn Waterworth, Salim Yusuf, Cecilia Lindgren, Mark I. McCarthy, Christoph Lange, Joel N. Hirschhorn, Nan Laird, H.-Erich Wichmann
PLoS Genet. 2009 Oct; 5(10): e1000694. Published online 2009 Oct 23. doi: 10.1371/journal.pgen.1000694
PMCID:
PMC2757909
AbstractArticlePDF–284K
14.
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts
Jan Bressler, Myriam Fornage, Craig L Hanis, Wen Hong Linda Kao, Cora E Lewis, Ruth McPherson, Robert Dent, Thomas H Mosley, Len A Pennacchio, Eric Boerwinkle
BMC Med Genet. 2009; 10: 56. Published online 2009 Jun 12. doi: 10.1186/1471-2350-10-56
PMCID:
PMC2706232
AbstractArticlePDF–275K
15.
Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis
Chang Gong Li, Mike Gruidl, Steven Eschrich, Susan McCarthy, Hong-Gang Wang, Mark G. Alexandrow, Timothy J. Yeatman
Int J Cancer. Author manuscript; available in PMC 2009 Mar 4.
Published in final edited form as: Int J Cancer. 2008 Jul 15; 123(2): 273–282. doi: 10.1002/ijc.23510
PMCID:
PMC2650850
AbstractArticlePDF–2.8M
16.
INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men
Funda E Orkunoglu-Suer, Heather Gordish-Dressman, Priscilla M Clarkson, Paul D Thompson, Theodore J Angelopoulos, Paul M Gordon, Niall M Moyna, Linda S Pescatello, Paul S Visich, Robert F Zoeller, Brennan Harmon, Richard L Seip, Eric P Hoffman, Joseph M Devaney
BMC Med Genet. 2008; 9: 117. Published online 2008 Dec 23. doi: 10.1186/1471-2350-9-117
PMCID:
PMC2646703
AbstractArticlePDF–290K
17.
INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese
Kikuko Hotta, Michihiro Nakamura, Yoshio Nakata, Tomoaki Matsuo, Seika Kamohara, Kazuaki Kotani, Ryoya Komatsu, Naoto Itoh, Ikuo Mineo, Jun Wada, Hiroaki Masuzaki, Masato Yoneda, Atsushi Nakajima, Shigeru Miyazaki, Katsuto Tokunaga, Manabu Kawamoto, Tohru Funahashi, Kazuyuki Hamaguchi, Kentaro Yamada, Toshiaki Hanafusa, Shinichi Oikawa, Hironobu Yoshimatsu, Kazuwa Nakao, Toshiie Sakata, Yuji Matsuzawa, Kiyoji Tanaka, Naoyuki Kamatani, Yusuke Nakamura
J Hum Genet. 2008 Sep; 53(9): 857–862. Published online 2008 Jul 10. doi: 10.1007/s10038-008-0317-8
PMCID:
PMC2522377
AbstractArticlePDF–177K
18.
The Association of a SNP Upstream of INSIG2 with Body Mass Index is Reproduced in Several but Not All Cohorts
Helen N Lyon, Valur Emilsson, Anke Hinney, Iris M Heid, Jessica Lasky-Su, Xiaofeng Zhu, Gudmar Thorleifsson, Steinunn Gunnarsdottir, G. Bragi Walters, Unnur Thorsteinsdottir, Augustine Kong, Jeffrey Gulcher, Thuy Trang Nguyen, André Scherag, Arne Pfeufer, Thomas Meitinger, Günter Brönner, Winfried Rief, Manuel E Soto-Quiros, Lydiana Avila, Barbara Klanderman, Benjamin A Raby, Edwin K Silverman, Scott T Weiss, Nan Laird, Xiao Ding, Leif Groop, Tiinamaija Tuomi, Bo Isomaa, Kristina Bengtsson, Johannah L Butler, Richard S Cooper, Caroline S Fox, Christopher J O'Donnell, Caren Vollmert, Juan C Celedón, H. Erich Wichmann, Johannes Hebebrand, Kari Stefansson, Christoph Lange, Joel N Hirschhorn
PLoS Genet. 2007 Apr; 3(4): e61. Prepublished online 2007 Mar 6. Published online 2007 Apr 27. doi: 10.1371/journal.pgen.0030061
PMCID:
PMC1857727
AbstractArticlePDF–122K
19.
INSIG-2 promoter polymorphism and obesity related phenotypes: association study in 1428 members of 248 families
Darroch H Hall, Thahira Rahman, Peter J Avery, Bernard Keavney
BMC Med Genet. 2006; 7: 83. Published online 2006 Nov 30. doi: 10.1186/1471-2350-7-83
PMCID:
PMC1698479
AbstractArticlePDF–239K
20.
Association of CNR1 and INSIG2 polymorphisms with antipsychotics-induced weight gain: a prospective nested case–control study
Natalia Jimeno, Veronica Velasco-Gonzalez, Inmaculada Fierro, Mercedes Duran, Alfonso Carvajal
Sci Rep. 2021; 11: 15304. Published online 2021 Jul 27. doi: 10.1038/s41598-021-94700-9
PMCID:
PMC8316361
AbstractArticlePDF–1.1M

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