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Items: 1 to 20 of 66

1.
Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy
Luca Gozzelino, Gaga Kochlamazashvili, Sara Baldassari, Albert Ian Mackintosh, Laura Licchetta, Emanuela Iovino, Yu Chi Liu, Caitlin A Bennett, Mark F Bennett, John A Damiano, Gábor Zsurka, Caterina Marconi, Tania Giangregorio, Pamela Magini, Marijn Kuijpers, Tanja Maritzen, Giuseppe Danilo Norata, Stéphanie Baulac, Laura Canafoglia, Marco Seri, Paolo Tinuper, Ingrid E Scheffer, Melanie Bahlo, Samuel F Berkovic, Michael S Hildebrand, Wolfram S Kunz, Lucio Giordano, Francesca Bisulli, Miriam Martini, Volker Haucke, Emilio Hirsch, Tommaso Pippucci
Brain. 2022 Jul; 145(7): 2313–2331. Published online 2022 Jul 4. doi: 10.1093/brain/awac082
PMCID:
PMC9337808
AbstractArticlePDF–1.5M
2.
Higher PIK3C2B gene expression of H1N1+ specific B-cells is associated with lower H1N1 immunogenicity after trivalent influenza vaccination in HIV infected children
Nicola Cotugno, Sonia Zicari, Elena Morrocchi, Lesley R. de Armas, Suresh Pallikkuth, Stefano Rinaldi, Alessandra Ruggiero, Emma Concetta Manno, Paola Zangari, Maria Chiriaco, Stefania Bernardi, Sarah F. Andrews, Alberto Cagigi, Paolo Rossi, Adrian B. McDermott, Savita Pahwa, Paolo Palma
Clin Immunol. Author manuscript; available in PMC 2021 Dec 28.
Published in final edited form as: Clin Immunol. 2020 Jun; 215: 108440. Published online 2020 Apr 21. doi: 10.1016/j.clim.2020.108440
PMCID:
PMC8714025
AbstractArticlePDF–1.0M
3.
Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth
Ouma Cisse, Muzthahid Quraishi, Federico Gulluni, Federica Guffanti, Ioanna Mavrommati, Methushaa Suthanthirakumaran, Lara C. R. Oh, Jessica N. Schlatter, Ambisha Sarvananthan, Massimo Broggini, Emilio Hirsch, Marco Falasca, Tania Maffucci
J Exp Clin Cancer Res. 2019; 38: 472. Published online 2019 Nov 21. doi: 10.1186/s13046-019-1472-9
PMCID:
PMC6873561
AbstractArticlePDF–4.5M
4.
Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis
Marcus Kind, Jolanta Klukowska-Rötzler, Sabina Berezowska, Alexandre Arcaro, Roch-Philippe Charles
PLoS One. 2017; 12(10): e0187308. Published online 2017 Oct 31. doi: 10.1371/journal.pone.0187308
PMCID:
PMC5663493
AbstractArticlePDF–5.2M
5.
Phosphatidylinositol 3-kinase, Class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis
Angela Russo, Mustafa Nazir Okur, Maarten Bosland, John P. O'Bryan
Cancer Lett. Author manuscript; available in PMC 2016 Apr 10.
Published in final edited form as: Cancer Lett. 2015 Apr 10; 359(2): 262–268. Published online 2015 Jan 23. doi: 10.1016/j.canlet.2015.01.026
PMCID:
PMC4351744
AbstractArticlePDF–632K
6.
A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation
Katy A. Wong, Angela Russo, Xuerong Wang, Yun-Ju Chen, Arnon Lavie, John P. O'Bryan
PLoS One. 2012; 7(9): e45360. Published online 2012 Sep 13. doi: 10.1371/journal.pone.0045360
PMCID:
PMC3441633
AbstractArticlePDF–1.5M
7.
Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation
Alexandre Arcaro, Umme K. Khanzada, Bart Vanhaesebroeck, Teresa D. Tetley, Michael D. Waterfield, Michael J. Seckl
EMBO J. 2002 Oct 1; 21(19): 5097–5108. doi: 10.1093/emboj/cdf512
PMCID:
PMC129034
AbstractArticlePDF–656K
8.
The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells
Khin Thuzar Aung, Kazuaki Yoshioka, Sho Aki, Kazuhiro Ishimaru, Noriko Takuwa, Yoh Takuwa
J Physiol Sci. 2019 Mar; 69(2): 263–280. Published online 2018 Oct 29. doi: 10.1007/s12576-018-0644-2
PMCID:
PMC10717547
AbstractArticlePDF–20M
9.
The Class II Phosphatidylinositol 3 kinase C2β Is Required for the Activation of the K+ Channel KCa3.1 and CD4 T-Cells
Shekhar Srivastava, Lie Di, Olga Zhdanova, Zhai Li, Santosha Vardhana, Qi Wan, Ying Yan, Rajat Varma, Jonathan Backer, Heike Wulff, Michael L. Dustin, Edward Y. Skolnik
Mol Biol Cell. 2009 Sep 1; 20(17): 3783–3791. doi: 10.1091/mbc.E09-05-0390
PMCID:
PMC2735477
AbstractArticlePDF–1.3M
10.
Phosphoinositide 3-Kinase C2β Regulates Cytoskeletal Organization and Cell Migration via Rac-dependent Mechanisms
Roy M. Katso, Olivier E. Pardo, Andrea Palamidessi, Clemens M. Franz, Marin Marinov, Angela De Laurentiis, Julian Downward, Giorgio Scita, Anne J. Ridley, Michael D. Waterfield, Alexandre Arcaro
Mol Biol Cell. 2006 Sep; 17(9): 3729–3744. doi: 10.1091/mbc.E05-11-1083
PMCID:
PMC1593155
AbstractArticlePDF–3.5M
11.
The Class II Phosphoinositide 3-Kinase C2β Is Not Essential for Epidermal Differentiation
Kazutoshi Harada, Amy B. Truong, Ti Cai, Paul A. Khavari
Mol Cell Biol. 2005 Dec; 25(24): 11122–11130. doi: 10.1128/MCB.25.24.11122-11130.2005
PMCID:
PMC1316983
AbstractArticlePDF–1.4M
12.
Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation
Soha Salama El Sheikh, Jan Domin, Prakitpunthu Tomtitchong, Paul Abel, Gordon Stamp, El-Nasir Lalani
BMC Clin Pathol. 2003; 3: 4. Published online 2003 Oct 16. doi: 10.1186/1472-6890-3-4
PMCID:
PMC280660
AbstractArticlePDF–740K
13.
Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
Gianpaolo Tibolla, Roberto Piñeiro, Daniela Chiozzotto, Ioanna Mavrommati, Ann P. Wheeler, Giuseppe Danilo Norata, Alberico Luigi Catapano, Tania Maffucci, Marco Falasca
PLoS One. 2013; 8(1): e53808. Published online 2013 Jan 8. doi: 10.1371/journal.pone.0053808
PMCID:
PMC3539993
AbstractArticlePDF–997K
14.
Recruitment of the Class II Phosphoinositide 3-Kinase C2β to the Epidermal Growth Factor Receptor: Role of Grb2
Matthew Wheeler, Jan Domin
Mol Cell Biol. 2001 Oct; 21(19): 6660–6667. doi: 10.1128/MCB.21.19.6660-6667.2001
PMCID:
PMC99811
AbstractArticlePDF–273K
15.
Differential Induction of Interleukin-10 in Monocytes by HIV-1 Clade B and Clade C Tat Proteins
Justine K. Wong, Grant R. Campbell, Stephen A. Spector
J Biol Chem. 2010 Jun 11; 285(24): 18319–18325. Published online 2010 Apr 8. doi: 10.1074/jbc.M110.120840
PMCID:
PMC2881757
AbstractArticlePDF–1.7M
16.
Pooled Analysis of Phosphatidylinositol 3-kinase Pathway Variants and Risk of Prostate Cancer
Stella Koutros, Fredrick R. Schumacher, Richard B. Hayes, Jing Ma, Wen-Yi Huang, Demetrius Albanes, Federico Canzian, Stephen J. Chanock, E. David Crawford, W. Ryan Diver, Heather Spencer Feigelson, Edward Giovanucci, Christopher A. Haiman, Brian E. Henderson, David J. Hunter, Rudolf Kaaks, Laurence N. Kolonel, Peter Kraft, Loïc Le Marchand, Elio Riboli, Afshan Siddiq, Mier J. Stampfer, Daniel O. Stram, Gilles Thomas, Ruth C. Travis, Michael J. Thun, Meredith Yeager, Sonja I. Berndt
Cancer Res. Author manuscript; available in PMC 2011 Mar 15.
Published in final edited form as: Cancer Res. 2010 Mar 15; 70(6): 2389–2396. Published online 2010 Mar 2. doi: 10.1158/0008-5472.CAN-09-3575
PMCID:
PMC2840184
AbstractArticlePDF–326K
17.
Class II Phosphoinositide 3-Kinases Are Downstream Targets of Activated Polypeptide Growth Factor Receptors
Alexandre Arcaro, Marketa J. Zvelebil, Christian Wallasch, Axel Ullrich, Michael D. Waterfield, Jan Domin
Mol Cell Biol. 2000 Jun; 20(11): 3817–3830. doi: 10.1128/mcb.20.11.3817-3830.2000
PMCID:
PMC85707
AbstractArticlePDF–4.2M
18.
Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β
Xinjiang Cai, Shekhar Srivastava, Yi Sun, Zhai Li, Haiyan Wu, Ljiljana Zuvela-Jelaska, Jun Li, Rachel S. Salamon, Jonathan M. Backer, Edward Y. Skolnik
Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50): 20072–20077. Published online 2011 Nov 29. doi: 10.1073/pnas.1111233109
PMCID:
PMC3250182
AbstractArticlePDF–720K
19.
Nef-Mediated Disruption of HLA-A2 Transport to the Cell Surface in T Cells
Matthew R. Kasper, Kathleen L. Collins
J Virol. 2003 Mar; 77(5): 3041–3049. doi: 10.1128/JVI.77.5.3041-3049.2003
PMCID:
PMC149742
AbstractArticlePDF–829K
20.
Phosphatidylinositol 3-Kinase Regulates Human Immunodeficiency Virus Type 1 Replication following Viral Entry in Primary CD4+ T Lymphocytes and Macrophages
Fleur François, Mary E. Klotman
J Virol. 2003 Feb; 77(4): 2539–2549. doi: 10.1128/JVI.77.4.2539-2549.2003
PMCID:
PMC141101
AbstractArticlePDF–1.4M

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