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Select item 95704061.

PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation

Mingquan Zhang, Rong Xiang, Christophe Glorieux, Peng Huang

Int J Mol Sci. 2022 Oct; 23(19): 11721. Published online 2022 Oct 3. doi: 10.3390/ijms231911721

PMCID:: PMC9570406

Abstract Article PDF–3.4M

Select item 89318852.

Secretory Phospholipase A2 Digital Expression Analysis in Colon Adenocarcinoma

EVANGELOS FALIDAS, EIRINI KITSIOULI, DESPOINA SPYROPOULOU, EVANGELOS TSIAMBAS, ASIMINA KALOGIROU, GEORGE TSOUVELAS, STYLIANOS PAPADOPOULOS, MICHAIL MITSIS, MARILENA LEKKA, SOFIANIKI MASTRONIKOLI, DIMITRIOS PESCHOS, ODYSSEAS DIMAS, KONSTANTINOS VLACHOS

In Vivo. 2022 Mar-Apr; 36(2): 738–742. Published online 2022 Mar 3. doi: 10.21873/invivo.12760

PMCID:: PMC8931885

Abstract Article PDF–749K

Select item 84837523.

Group IIA secreted phospholipase A₂ is associated with the pathobiology leading to COVID-19 mortality

Justin M. Snider, Jeehyun Karen You, Xia Wang, Ashley J. Snider, Brian Hallmark, Manja M. Zec, Michael C. Seeds, Susan Sergeant, Laurel Johnstone, Qiuming Wang, Ryan Sprissler, Tara F. Carr, Karen Lutrick, Sairam Parthasarathy, Christian Bime, Hao Helen Zhang, Chiara Luberto, Richard R. Kew, Yusuf A. Hannun, Stefano Guerra, Charles E. McCall, Guang Yao, Maurizio Del Poeta, Floyd H. Chilton

J Clin Invest. 2021 Oct 1; 131(19): e149236. Published online 2021 Oct 1. doi: 10.1172/JCI149236

PMCID:: PMC8483752

Abstract Article PDF–3.2M

Select item 75839694.

Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A₂

Ryung Rae Kim, Zheng Chen, Timothy J. Mann, Karine Bastard, Kieran F. Scott, W. Bret Church

Molecules. 2020 Oct; 25(19): 4459. Published online 2020 Sep 28. doi: 10.3390/molecules25194459

PMCID:: PMC7583969

Abstract Article PDF–2.7M

Select item 70976515.

Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A₂

R.W. Schevitz, N.J. Bach, D.G. Carlson, N.Y. Chirgadze, D.K. Clawson, R.D. Dillard, S.E. Draheim, L.W. Hartley, N.D. Jones, E.D. Mihelich, J.L. Olkowski, D.W. Snyder, C. Sommers, J.-P. Wery

Nat Struct Biol. 1995; 2(6): 458–465. doi: 10.1038/nsb0695-458

PMCID:: PMC7097651

Abstract Article PDF–11M

Select item 68384356.

Context-dependent effect of sPLA₂-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer

Gopal L. Chovatiya, Raghava R. Sunkara, Sayoni Roy, Saloni R. Godbole, Sanjeev K. Waghmare

EBioMedicine. 2019 Oct; 48: 364–376. Published online 2019 Sep 11. doi: 10.1016/j.ebiom.2019.08.053

PMCID:: PMC6838435

Abstract Article PDF–6.8M

Select item 60568527.

Group IIA-Secreted Phospholipase A₂ in Human Serum Kills Commensal but Not Clinical Enterococcus faecium Isolates

Fernanda L. Paganelli, Helen L. Leavis, Samantha He, Nina M. van Sorge, Christine Payré, Gérard Lambeau, Rob J. L. Willems, Suzan H. M. Rooijakkers

Infect Immun. 2018 Aug; 86(8): e00180-18. Prepublished online 2018 May 21. Published online 2018 Jul 23. doi: 10.1128/IAI.00180-18

PMCID:: PMC6056852

Abstract Article PDF–759K

Select item 59450488.

Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus

Susann Liebscher, Rebecca L. Ambrose, Turgut E. Aktepe, Andrea Mikulasova, Julia E. Prier, Leah K. Gillespie, Adam J. Lopez-Denman, Thusitha W. T. Rupasinghe, Dedreia Tull, Malcolm J. McConville, Jason M. Mackenzie

PLoS Pathog. 2018 Apr; 14(4): e1007029. Published online 2018 Apr 30. doi: 10.1371/journal.ppat.1007029

PMCID:: PMC5945048

Abstract Article PDF–11M

Select item 55808969.

Secretory phospholipase A₂ group IIA modulates insulin sensitivity and metabolism

Michael S. Kuefner, Kevin Pham, Jeanna R. Redd, Erin J. Stephenson, Innocence Harvey, Xiong Deng, Dave Bridges, Eric Boilard, Marshall B. Elam, Edwards A. Park

J Lipid Res. 2017 Sep; 58(9): 1822–1833. Published online 2017 Jun 29. doi: 10.1194/jlr.M076141

PMCID:: PMC5580896

Abstract Article PDF–1.3M

Select item 532216110.

Secretory phospholipase A2 in the pathogenesis of acute dengue infection

Chandima Jeewandara, Laksiri Gomes, Sukhitha Udari, S.A. Paranavitane, N.L.A. Shyamali, Graham S. Ogg, Gathsaurie Neelika Malavige

Immun Inflamm Dis. 2017 Mar; 5(1): 7–15. Published online 2016 Dec 11. doi: 10.1002/iid3.135

PMCID:: PMC5322161

Abstract Article PDF–476K

Select item 522550211.

Promoting effect of hepatitis B virus on the expressoin of phospholipase A2 group IIA

Chengliang Zhu, Hui Song, Bingzheng Shen, Long Wu, Fang Liu, Xinghui Liu

Lipids Health Dis. 2017; 16: 5. Published online 2017 Jan 11. doi: 10.1186/s12944-016-0400-7

PMCID:: PMC5225502

Abstract Article PDF–1.1M

Select item 515025012.

Elevated Type II Secretory Phospholipase A2 Increases the Risk of Early Atherosclerosis in Patients with Newly Diagnosed Metabolic Syndrome

Chang-Qing Sun, Chun-Yan Zhong, Wei-Wei Sun, Hua Xiao, Ping Zhu, Yi-Zhang Lin, Chen-Liang Zhang, Hao Gao, Zhi-Yuan Song

Sci Rep. 2016; 6: 34929. Published online 2016 Dec 12. doi: 10.1038/srep34929

PMCID:: PMC5150250

Abstract Article PDF–709K

Select item 445171413.

Secretory Phospholipases A₂ Are Secreted From Ciliated Cells and Increase Mucin and Eicosanoid Secretion From Goblet Cells

Tsuyoshi Tanabe, Tadasuke Shimokawaji, Soichiro Kanoh, Bruce K. Rubin

Chest. 2015 Jun; 147(6): 1599–1609. Published online 2014 Nov 27. doi: 10.1378/chest.14-0258

PMCID:: PMC4451714

Abstract Article PDF–1.9M

Select item 440032514.

Substrate Efflux Propensity Is the Key Determinant of Ca²⁺-independent Phospholipase A-β (iPLAβ)-mediated Glycerophospholipid Hydrolysis

Krishna Chaithanya Batchu, Kati Hokynar, Michael Jeltsch, Kenny Mattonet, Pentti Somerharju

J Biol Chem. 2015 Apr 17; 290(16): 10093–10103. Published online 2015 Feb 23. doi: 10.1074/jbc.M115.642835

PMCID:: PMC4400325

Abstract Article PDF–703K

Select item 412140415.

Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells

ZHONGYUN DONG, JAROSLAW MELLER, PAUL SUCCOP, JIANG WANG, KATHRYN WIKENHEISER-BROKAMP, SANDRA STARNES, SHAN LU

Int J Oncol. 2014 Sep; 45(3): 978–984. Published online 2014 Jun 10. doi: 10.3892/ijo.2014.2486

PMCID:: PMC4121404

Abstract Article PDF–549K

Select item 405725416.

Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants

Daniele De Luca, Elena Lopez-Rodriguez, Angelo Minucci, Francesca Vendittelli, Leonarda Gentile, Eleonora Stival, Giorgio Conti, Marco Piastra, Massimo Antonelli, Mercedes Echaide, Jesus Perez-Gil, Ettore D Capoluongo

Crit Care. 2013; 17(4): R163. Published online 2013 Jul 24. doi: 10.1186/cc12842

PMCID:: PMC4057254

Abstract Article PDF–550K

Select item 397897417.

Role of secretory phospholipase A₂ in women with metabolic syndrome

D. Pop, A. Sitar-Tǎut, G. Bodisz, D. Zdrenghea, M. Cebanu, L. Stanca

Indian J Med Res. 2013 Dec; 138(6): 866–872.

PMCID:: PMC3978974

Abstract Article PDF–933K

Select item 385027718.

Knockdown of secretory phospholipase A2 IIa reduces lung cancer growth in vitro and in vivo

Jessica A. Yu, David Mauchley, Howard Li, Xianzhong Meng, Raphael A. Nemenoff, David A. Fullerton, Michael J. Weyant

J Thorac Cardiovasc Surg. Author manuscript; available in PMC 2013 Dec 4.

Published in final edited form as: J Thorac Cardiovasc Surg. 2012 Nov; 144(5): 10.1016/j.jtcvs.2012.08.003. doi: 10.1016/j.jtcvs.2012.08.003

PMCID:: PMC3850277

Abstract Article PDF–1.0M

Select item 357981719.

Elevated Phospholipase A₂ Activities in Plasma Samples from Multiple Cancers

Hui Cai, Elena G. Chiorean, Michael V. Chiorean, Douglas K. Rex, Bruce W. Robb, Noah M. Hahn, Ziyue Liu, Patrick J. Loehrer, Marietta L. Harrison, Yan Xu

PLoS One. 2013; 8(2): e57081. Published online 2013 Feb 22. doi: 10.1371/journal.pone.0057081

PMCID:: PMC3579817

Abstract Article PDF–2.4M

Select item 334532020.

Secretory Phospholipase A2-IIa is a Target Gene of the HER/HER2-Elicited Pathway and a Potential Plasma Biomarker for Poor Prognosis of Prostate Cancer

Leslie Oleksowicz, Yin Liu, R. Bruce Bracken, Krishnanath Gaitonde, Barbara Burke, Paul Succop, Linda Levin, Zhongyun Dong, Shan Lu

Prostate. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Prostate. 2012 Jul 1; 72(10): 1140–1149. Published online 2011 Nov 29. doi: 10.1002/pros.22463

PMCID:: PMC3345320

Abstract Article PDF–2.7M

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