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Items: 1 to 20 of 94

1.
Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock
Sara Ahadi, Kenneth A Wilson, Boris Babenko, Cory Y McLean, Drew Bryant, Orion Pritchard, Ajay Kumar, Enrique M Carrera, Ricardo Lamy, Jay M Stewart, Avinash Varadarajan, Marc Berndl, Pankaj Kapahi, Ali Bashir
eLife. 2023; 12: e82364. Published online 2023 Apr 17. doi: 10.7554/eLife.82364
PMCID:
PMC10110236
AbstractArticlePDF–4.0M
2.
The Neuroblastoma ALK(I1250T) Mutation Is a Kinase-Dead RTK In Vitro and In Vivo
Christina Schönherr, Kristina Ruuth, Therese Eriksson, Yasuo Yamazaki, Christian Ottmann, Valerie Combaret, Marc Vigny, Sattu Kamaraj, Ruth H Palmer, Bengt Hallberg
Transl Oncol. 2011 Aug; 4(4): 258–265. Published online 2011 Aug 1. doi: 10.1593/tlo.11139
PMCID:
PMC3140014
AbstractArticlePDF–2.6M
3.
The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system
Sanjay Kumar Sukumar, Vimala Antonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-Garcia, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
eLife. 2024; 12: RP88985. Published online 2024 Jun 21. doi: 10.7554/eLife.88985
PMCID:
PMC11196111
AbstractArticlePDF–22M
4.
The Drosophila Receptor Tyrosine Kinase Alk Constrains Long-Term Memory Formation
Jean Y. Gouzi, Mikela Bouraimi, Ilianna G. Roussou, Anastasios Moressis, Efthimios M.C. Skoulakis
J Neurosci. 2018 Aug 29; 38(35): 7701–7712. doi: 10.1523/JNEUROSCI.0784-18.2018
PMCID:
PMC6705970
AbstractArticlePDF–2.6M
5.
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma
Damini Chand, Yasuo Yamazaki, Kristina Ruuth, Christina Schönherr, Tommy Martinsson, Per Kogner, Edward F. Attiyeh, John Maris, Olena Morozova, Marco A. Marra, Miki Ohira, Akira Nakagawara, Per-Erik Sandström, Ruth H. Palmer, Bengt Hallberg
Dis Model Mech. 2013 Mar; 6(2): 373–382. Published online 2012 Oct 25. doi: 10.1242/dmm.010348
PMCID:
PMC3597019
AbstractArticle
6.
Social Behavioral Deficits with Loss of Neurofibromin Emerge from Peripheral Chemosensory Neuron Dysfunction
Emilia H. Moscato, Christine Dubowy, James A. Walker, Matthew S. Kayser
Cell Rep. Author manuscript; available in PMC 2020 Aug 10.
Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107856. doi: 10.1016/j.celrep.2020.107856
PMCID:
PMC7416787
AbstractArticlePDF–1.9M
7.
An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol
Amy W. Lasek, Jana Lim, Christopher L. Kliethermes, Karen H. Berger, Geoff Joslyn, Gerry Brush, Liquan Xue, Margaret Robertson, Monica S. Moore, Karen Vranizan, Stephan W. Morris, Marc A. Schuckit, Raymond L. White, Ulrike Heberlein
PLoS One. 2011; 6(7): e22636. Published online 2011 Jul 22. doi: 10.1371/journal.pone.0022636
PMCID:
PMC3142173
AbstractArticlePDF–569K
8.
Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
Kathrin Pfeifer, Georg Wolfstetter, Vimala Anthonydhason, Tafheem Masudi, Badrul Arefin, Mats Bemark, Patricia Mendoza-Garcia, Ruth H. Palmer
Dis Model Mech. 2022 Aug 1; 15(8): dmm049591. Published online 2022 Aug 16. doi: 10.1242/dmm.049591
PMCID:
PMC9403751
AbstractArticle
9.
Aberrant role of ALK in tau proteinopathy through autophagosomal dysregulation
Jisu Park, Hyunwoo Choi, Young Doo Kim, Seo-Hyun Kim, Youbin Kim, Youngdae Gwon, Dong Young Lee, Sung-Hye Park, Won Do Heo, Yong-Keun Jung
Mol Psychiatry. 2021; 26(10): 5542–5556. Published online 2021 Jan 15. doi: 10.1038/s41380-020-01003-y
PMCID:
PMC8758490
AbstractArticlePDF–3.9M
10.
Eyeless uncouples mushroom body neuroblast proliferation from dietary amino acids in Drosophila
Conor W Sipe, Sarah E Siegrist
eLife. 2017; 6: e26343. Published online 2017 Aug 9. doi: 10.7554/eLife.26343
PMCID:
PMC5576483
AbstractArticlePDF–4.4M
11.
A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth
James A Walker, André Bernards
Rare Dis. 2014; 2: e28341. Published online 2014 Feb 25. doi: 10.4161/rdis.28341
PMCID:
PMC4091572
AbstractArticlePDF–466K
12.
Multiple Interactions Control Synaptic Layer Specificity in the Drosophila Visual System
Matthew Y. Pecot, Wael Tadros, Aljoscha Nern, Maya Bader, Yi Chen, S. Lawrence Zipursky
Neuron. Author manuscript; available in PMC 2013 Jul 23.
Published in final edited form as: Neuron. 2013 Jan 23; 77(2): 299–310. doi: 10.1016/j.neuron.2012.11.007
PMCID:
PMC3684158
AbstractArticlePDF–8.3M
13.
The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning
Jean Y. Gouzi, Anastasios Moressis, James A. Walker, Anthi A. Apostolopoulou, Ruth H. Palmer, André Bernards, Efthimios M. C. Skoulakis
PLoS Genet. 2011 Sep; 7(9): e1002281. Published online 2011 Sep 15. doi: 10.1371/journal.pgen.1002281
PMCID:
PMC3174217
AbstractArticlePDF–1.0M
14.
A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster
Christina E. Lorén, Camilla Englund, Caroline Grabbe, Bengt Hallberg, Tony Hunter, Ruth H. Palmer
EMBO Rep. 2003 Aug; 4(8): 781–786. Published online 2003 Jul 4. doi: 10.1038/sj.embor.embor897
PMCID:
PMC1326337
AbstractArticlePDF–385K
15.
Neurofibromin 1 regulates early developmental sleep in Drosophila
Jaclyn Durkin, Amy R. Poe, Samuel J. Belfer, Anyara Rodriguez, Si Hao Tang, James A. Walker, Matthew S. Kayser
Neurobiol Sleep Circadian Rhythms. 2023 Nov; 15: 100101. Published online 2023 Aug 9. doi: 10.1016/j.nbscr.2023.100101
PMCID:
PMC10428071
AbstractArticlePDF–8.8M
16.
Anaplastic Lymphoma Kinase Acts in the Drosophila Mushroom Body to Negatively Regulate Sleep
Lei Bai, Amita Sehgal
PLoS Genet. 2015 Nov; 11(11): e1005611. Published online 2015 Nov 4. doi: 10.1371/journal.pgen.1005611
PMCID:
PMC4633181
AbstractArticlePDF–2.4M
17.
Sequential Axon-derived Signals Couple Target Survival and Layer Specificity in the Drosophila Visual System
Matthew Y. Pecot, Yi Chen, Orkun Akin, Zhenqing Chen, C.Y. Kimberly Tsui, S. Lawrence Zipursky
Neuron. Author manuscript; available in PMC 2015 Apr 16.
Published in final edited form as: Neuron. 2014 Apr 16; 82(2): 320–333. doi: 10.1016/j.neuron.2014.02.045
PMCID:
PMC4304384
AbstractArticlePDF–6.7M
18.
Pleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus
Celia González-Castillo, Daniel Ortuño-Sahagún, Carolina Guzmán-Brambila, Mercè Pallàs, Argelia Esperanza Rojas-Mayorquín
Front Cell Neurosci. 2014; 8: 443. Published online 2015 Jan 8. doi: 10.3389/fncel.2014.00443
PMCID:
PMC4287103
AbstractArticlePDF–639K
19.
The Drosophila Midkine/Pleiotrophin Homologues Miple1 and Miple2 Affect Adult Lifespan but Are Dispensable for Alk Signaling during Embryonic Gut Formation
Fredrik Hugosson, Camilla Sjögren, Anna Birve, Ludmilla Hedlund, Therese Eriksson, Ruth H. Palmer
PLoS One. 2014; 9(11): e112250. Published online 2014 Nov 7. doi: 10.1371/journal.pone.0112250
PMCID:
PMC4224452
AbstractArticlePDF–21M
20.
Building a brain under nutritional restriction: insights on sparing and plasticity from Drosophila studies
Elodie Lanet, Cédric Maurange
Front Physiol. 2014; 5: 117. Published online 2014 Mar 26. doi: 10.3389/fphys.2014.00117
PMCID:
PMC3972452
AbstractArticlePDF–1.1M

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