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Select item 101889071.

Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy

Jia-Lu Liu, Lei Zhang, Ying Huang, Xiao-Hui Li, Yi-Fei Liu, Shu-Min Zhang, Yue-E Zhao, Xiao-Jun Chen, Yu Liu, Li-Yu He, Zheng Dong, Fu-You Liu, Lin Sun, Li Xiao

Mol Ther. 2023 May 3; 31(5): 1451–1467. Published online 2023 Apr 3. doi: 10.1016/j.ymthe.2023.03.027

PMCID:: PMC10188907

Abstract Article PDF–8.5M

Select item 92995112.

Dll4 Inhibition Promotes Graft Retention in Fat Grafting Enriched with Adipose-Derived Stem Cells

Choong-kun Lee, Bo-Yoon Park, Taehee Jo, Cheol-Heum Park, Ju-Hee Kim, Kyu-Jin Chung, Yong-Ha Kim, Do Young Park, Il-Kug Kim

Stem Cells Transl Med. 2022 Jul; 11(7): 742–752. Published online 2022 May 17. doi: 10.1093/stcltm/szac034

PMCID:: PMC9299511

Abstract Article PDF–79M

Select item 77717113.

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model

Adilson Kleber Ferreira, Brunella Cristofaro, Milene Cristina Menezes, Ana Karina de Oliveira, Alexandre Keiji Tashima, Robson Lopes de Melo, Cristiane Castilho Fernandes Silva, Miryam Guillermina Palomino Rodriguez, Daniela Cajado de Oliveira Souza Carvalho, Ricardo Alexandre de Azevedo, Paulo Luiz de Sá Junior, Lisley Inata Mambelli, Fernanda Vieira Portaro, Luc Pardanaud, Anne Eichmann, Osvaldo Augusto Sant’Anna, Mxarcella Faria

Oncotarget. 2020 Dec 22; 11(51): 4770–4787. Published online 2020 Dec 22. doi: 10.18632/oncotarget.27839

PMCID:: PMC7771711

Abstract Article PDF–7.2M

Select item 61603454.

Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection

Hung-An Ting, Denise de Almeida Nagata, Andrew J Rasky, Carrie-Anne Malinczak, Ivan P Maillard, Matthew A Schaller, Nicholas W Lukacs

Mucosal Immunol. Author manuscript; available in PMC 2019 Jan 23.

Published in final edited form as: Mucosal Immunol. 2018 Sep; 11(5): 1524–1536. Published online 2018 Jul 23. doi: 10.1038/s41385-018-0052-1

PMCID:: PMC6160345

Abstract Article PDF–2.2M

Select item 53488805.

Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo

Alexandre Trindade, Dusan Djokovic, Joana Gigante, Liliana Mendonça, António Duarte

BMC Cancer. 2017; 17: 189. Published online 2017 Mar 14. doi: 10.1186/s12885-017-3171-2

PMCID:: PMC5348880

Abstract Article PDF–5.4M

Select item 45521326.

Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomas

Dusan Djokovic, Alexandre Trindade, Joana Gigante, Mario Pinho, Adrian L. Harris, Antonio Duarte

BMC Cancer. 2015; 15: 608. Published online 2015 Aug 28. doi: 10.1186/s12885-015-1605-2

PMCID:: PMC4552132

Abstract Article PDF–2.0M

Select item 34964807.

Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages

Serge Camelo, William Raoul, Sophie Lavalette, Bertrand Calippe, Brunella Cristofaro, Olivier Levy, Marianne Houssier, Eric Sulpice, Laurent Jonet, Christophe Klein, Estelle Devevre, Gilles Thuret, Antonio Duarte, Anne Eichmann, Laurence Leconte, Xavier Guillonneau, Florian Sennlaub

Angiogenesis. 2012; 15(4): 609–622. Published online 2012 Aug 7. doi: 10.1007/s10456-012-9290-0

Correction in:: Angiogenesis. 2013; 16(2): 479–480.

PMCID:: PMC3496480

Abstract Article PDF–1.0M

Select item 33260248.

The Notch Ligand Delta-Like 4 Regulates Multiple Stages of Early Hemato-Vascular Development

Ricardo Laranjeiro, Isabel Alcobia, Hélia Neves, Andreia C. Gomes, Pedro Saavedra, Catarina C. Carvalho, António Duarte, António Cidadão, Leonor Parreira

PLoS One. 2012; 7(4): e34553. Published online 2012 Apr 13. doi: 10.1371/journal.pone.0034553

PMCID:: PMC3326024

Abstract Article PDF–1.2M

Select item 32611619.

Low-Dosage Inhibition of Dll4 Signaling Promotes Wound Healing by Inducing Functional Neo-Angiogenesis

Alexandre Trindade, Dusan Djokovic, Joana Gigante, Marina Badenes, Ana-Rita Pedrosa, Ana-Carina Fernandes, Luís Lopes-da-Costa, Valery Krasnoperov, Ren Liu, Parkash S. Gill, António Duarte

PLoS One. 2012; 7(1): e29863. Published online 2012 Jan 18. doi: 10.1371/journal.pone.0029863

PMCID:: PMC3261161

Abstract Article PDF–3.9M

Select item 315980110.

Delta-like Ligand 4 Regulates CNS T Cell Accumulation during Experimental Autoimmune Encephalomyelitis

Nathanael D. Reynolds, Nicholas W. Lukacs, Nancy Long, William J. Karpus

J Immunol. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: J Immunol. 2011 Sep 1; 187(5): 2803–2813. Published online 2011 Jul 25. doi: 10.4049/jimmunol.1100160

PMCID:: PMC3159801

Abstract Article PDF–1.7M

Select item 307071811.

Bone Marrow-Derived Endothelial Progenitors Expressing Delta-Like 4 (Dll4) Regulate Tumor Angiogenesis

Carla Real, Leonor Remédio, Francisco Caiado, Cátia Igreja, Cristina Borges, Alexandre Trindade, Perpétua Pinto-do-Ó, Hideo Yagita, Antonio Duarte, Sérgio Dias

PLoS One. 2011; 6(4): e18323. Published online 2011 Apr 4. doi: 10.1371/journal.pone.0018323

PMCID:: PMC3070718

Abstract Article PDF–4.8M

Select item 303149012.

Delta-like ligand 4–Notch signaling regulates bone marrow–derived pericyte/vascular smooth muscle cell formation

Keri Schadler Stewart, Zhichao Zhou, Patrick Zweidler-McKay, Eugenie S. Kleinerman

Blood. 2011 Jan 13; 117(2): 719–726. Prepublished online 2010 Oct 13. doi: 10.1182/blood-2010-05-284869

PMCID:: PMC3031490

Abstract Article

Select item 257192613.

Delta-like 4 is indispensable in thymic environment specific for T cell development

Katsuto Hozumi, Carolina Mailhos, Naoko Negishi, Ken-ichi Hirano, Takashi Yahata, Kiyoshi Ando, Saulius Zuklys, Georg A. Holländer, David T. Shima, Sonoko Habu

J Exp Med. 2008 Oct 27; 205(11): 2507–2513. doi: 10.1084/jem.20080134

PMCID:: PMC2571926

Abstract Article PDF–3.5M

Select item 180553014.

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

I. B. Lobov, R. A. Renard, N. Papadopoulos, N. W. Gale, G. Thurston, G. D. Yancopoulos, S. J. Wiegand

Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9): 3219–3224. Published online 2007 Feb 12. doi: 10.1073/pnas.0611206104

PMCID:: PMC1805530

Abstract Article PDF–4.4M

Select item 1086157815.

Palmitic acid in type 2 diabetes mellitus promotes atherosclerotic plaque vulnerability via macrophage Dll4 signaling

Xiqiang Wang, Ling Zhu, Jing Liu, Yanpeng Ma, Chuan Qiu, Chengfeng Liu, Yangchao Gong, Ya Yuwen, Gongchang Guan, Yong Zhang, Shuo Pan, Junkui Wang, Zhongwei Liu

Nat Commun. 2024; 15: 1281. Published online 2024 Feb 12. doi: 10.1038/s41467-024-45582-8

PMCID:: PMC10861578

Abstract Article PDF–4.5M

Select item 698687616.

Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice

Ken-ichi Hirano, Akiko Suganami, Yutaka Tamura, Hideo Yagita, Sonoko Habu, Motoo Kitagawa, Takehito Sato, Katsuto Hozumi

eLife. 2020; 9: e50979. Published online 2020 Jan 16. doi: 10.7554/eLife.50979

PMCID:: PMC6986876

Abstract Article PDF–953K

Select item 649657117.

miRNA‐30e regulates abnormal differentiation of small intestinal epithelial cells in diabetic mice by downregulating Dll4 expression

Ti‐Dong Shan, Hui Ouyang, Tao Yu, Jie‐Yao Li, Can‐Ze Huang, Hong‐Sheng Yang, Wa Zhong, Zhong‐Sheng Xia, Qi‐Kui Chen

Cell Prolif. 2016 Feb; 49(1): 102–114. Published online 2016 Jan 19. doi: 10.1111/cpr.12230

PMCID:: PMC6496571

Abstract Article PDF–1.5M

Select item 523728818.

Delta-like 4/Notch signaling promotes Apc^Min/+ tumor initiation through angiogenic and non-angiogenic related mechanisms

Marina Badenes, Alexandre Trindade, Hugo Pissarra, Luís Lopes-da-Costa, António Duarte

BMC Cancer. 2017; 17: 50. Published online 2017 Jan 13. doi: 10.1186/s12885-016-3036-0

Correction in:: BMC Cancer. 2017; 17: 205.

PMCID:: PMC5237288

Abstract Article PDF–15M

Select item 512756919.

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr^-/- Mice

Mike L. J. Jeurissen, Sofie M. A. Walenbergh, Tom Houben, Tim Hendrikx, Jieyi Li, Yvonne Oligschlaeger, Patrick J. van Gorp, Marion J. J. Gijbels, Albert Bitorina, Isabell Nessel, Freddy Radtke, Marc Vooijs, Jan Theys, Ronit Shiri-Sverdlov

PLoS One. 2016; 11(11): e0167199. Published online 2016 Nov 29. doi: 10.1371/journal.pone.0167199

PMCID:: PMC5127569

Abstract Article PDF–2.4M

Select item 500311720.

Macrophage Notch ligand Delta-like 4 promotes vein graft lesion development: implications for the treatment of vein graft failure

Jun-ichiro Koga, Toshiaki Nakano, James E. Dahlman, Jose-Luiz Figueiredo, Hengmin Zhang, Julius Decano, Omar F Khan, Tomiharu Niida, Hiroshi Iwata, Jon C. Aster, Hideo Yagita, Daniel G. Anderson, C. Keith Ozaki, Masanori Aikawa

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Nov; 35(11): 2343–2353. Published online 2015 Sep 24. doi: 10.1161/ATVBAHA.115.305516

Correction in:: Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3): e25.

PMCID:: PMC5003117

Abstract Article PDF–3.4M

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