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Items: 1 to 20 of 258

1.
The Natural Tumorcide Manumycin-A Reduces Hydrogen Peroxide and Targets Protein Phosphatase 1α To Induce Lymphoma Apoptosis
Sanjit K. Roy, Gregory B. Carey, Hanako Daino
Exp Cell Res. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Exp Cell Res. 2015 Mar 1; 332(1): 136–145. Published online 2014 Dec 30. doi: 10.1016/j.yexcr.2014.12.009
PMCID:
PMC9976551
AbstractArticlePDF–1.9M
2.
Effects of stably incorporated iron on protein phosphatase‐1 structure and activity
Francesca Salvi, Malgorzata Trebacz, Thomas Kokot, Bernhard Hoermann, Pablo Rios, Orsolya Barabas, Maja Kӧhn
FEBS Lett. 2018 Dec; 592(24): 4028–4038. Published online 2018 Nov 23. doi: 10.1002/1873-3468.13284
PMCID:
PMC6587554
AbstractArticlePDF–888K
3.
A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Dan Wu, Veerle De Wever, Rita Derua, Claudia Winkler, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
J Biol Chem. 2018 Sep 28; 293(39): 15152–15162. Published online 2018 Aug 16. doi: 10.1074/jbc.RA118.004132
PMCID:
PMC6166715
AbstractArticlePDF–2.9M
4.
Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure Based Drug Design of Serine/Threonine Phosphatase Inhibitors
Matthew S. Kelker, Rebecca Page, Wolfgang Peti
J Mol Biol. Author manuscript; available in PMC 2010 Jan 9.
Published in final edited form as: J Mol Biol. 2009 Jan 9; 385(1): 11–21. Published online 2008 Nov 1. doi: 10.1016/j.jmb.2008.10.053
PMCID:
PMC2652124
AbstractArticlePDF–2.2M
5.
Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer
Wenjun Xie, Ying Sun, Yu Zeng, Linfei Hu, Jingtai Zhi, Hang Ling, Xiangqian Zheng, Xianhui Ruan, Ming Gao
Bioengineered. 2022; 13(1): 190–205. Published online 2021 Dec 29. doi: 10.1080/21655979.2021.2012316
PMCID:
PMC8805822
AbstractArticlePDF–5.5M
6.
Evolutionary crossroads of cell signaling: PP1 and PP2A substrate sites in intrinsically disordered regions
Bernhard Hoermann, Maja Köhn
Biochem Soc Trans. 2021 Jun 30; 49(3): 1065–1074. Published online 2021 Jun 8. doi: 10.1042/BST20200175
PMCID:
PMC8286827
AbstractArticlePDF–2.2M
7.
Protein phosphatase 1 alpha enhances glucocorticoid receptor activity by a mechanism involving phosphorylation of serine-211
Melanie Patt, Joël Gysi, Nourdine Faresse, John A. Cidlowski, Alex Odermatt
Mol Cell Endocrinol. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: Mol Cell Endocrinol. 2020 Dec 1; 518: 110873. Published online 2020 Jun 22. doi: 10.1016/j.mce.2020.110873
PMCID:
PMC7606615
AbstractArticlePDF–950K
8.
Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A
Bernhard Hoermann, Thomas Kokot, Dominic Helm, Stephanie Heinzlmeir, Jeremy E. Chojnacki, Thomas Schubert, Christina Ludwig, Anna Berteotti, Nils Kurzawa, Bernhard Kuster, Mikhail M. Savitski, Maja Köhn
Nat Commun. 2020; 11: 3583. Published online 2020 Jul 17. doi: 10.1038/s41467-020-17334-x
PMCID:
PMC7367873
AbstractArticlePDF–2.8M
9.
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway
Hongze Sun, Baochi Ou, Senlin Zhao, Xueni Liu, Liwei Song, Xisheng Liu, Rangrang Wang, Zhihai Peng
EBioMedicine. 2019 Oct; 48: 236–247. Published online 2019 Sep 11. doi: 10.1016/j.ebiom.2019.08.061
PMCID:
PMC6838424
AbstractArticlePDF–5.5M
10.
SDS22 selectively recognizes and traps metal-deficient inactive PP1
Meng S. Choy, Thomas M. Moon, Rini Ravindran, Johnny A. Bray, Lucy C. Robinson, Tara L. Archuleta, Wuxian Shi, Wolfgang Peti, Kelly Tatchell, Rebecca Page
Proc Natl Acad Sci U S A. 2019 Oct 8; 116(41): 20472–20481. Published online 2019 Sep 23. doi: 10.1073/pnas.1908718116
PMCID:
PMC6789808
AbstractArticlePDF–2.6M
11.
PPP1R35 ensures centriole homeostasis by promoting centriole-to-centrosome conversion
Chii Shyang Fong, Kanako Ozaki, Meng-Fu Bryan Tsou
Mol Biol Cell. 2018 Nov 15; 29(23): 2801–2808. doi: 10.1091/mbc.E18-08-0525
PMCID:
PMC6249868
AbstractArticlePDF–1.2M
12.
Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform
Brandon E. Aubol, Kendra L. Hailey, Laurent Fattet, Patricia A. Jennings, Joseph A. Adams
J Mol Biol. Author manuscript; available in PMC 2018 Jul 7.
Published in final edited form as: J Mol Biol. 2017 Jul 7; 429(14): 2178–2191. Published online 2017 May 31. doi: 10.1016/j.jmb.2017.05.022
PMCID:
PMC5536852
AbstractArticlePDF–2.2M
13.
Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer
Xiaming Liu, Yanfei Gao, HuiHui Ye, Sean Gerrin, Fen Ma, Yiming Wu, Tengfei Zhang, Joshua Russo, Changmeng Cai, Xin Yuan, Jihong Liu, Shaoyong Chen, Steven P. Balk
Nucleic Acids Res. 2017 Apr 20; 45(7): 3738–3751. Published online 2017 Jan 6. doi: 10.1093/nar/gkw1291
PMCID:
PMC5397168
AbstractArticlePDF–5.5M
14.
Protein phosphatase 1 abrogates IRF7-mediated type I IFN response in antiviral immunity
Ling Wang, Juan Zhao, Junping Ren, Kenton H. Hall, Jonathan P. Moorman, Zhi Q. Yao, Shunbin Ning
Eur J Immunol. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Eur J Immunol. 2016 Oct; 46(10): 2409–2419. Published online 2016 Aug 29. doi: 10.1002/eji.201646491
PMCID:
PMC5175453
AbstractArticlePDF–1.1M
15.
The K898E germline variant in the PP1-binding motif of BRCA1 causes defects in DNA Repair
Bert Yu-Hung Chen, Cheng-Hsiang Huang, Ying-Hsi Lin, Ching-Chun Huang, Chu-Xia Deng, Lih-Ching Hsu
Sci Rep. 2014; 4: 5812. Published online 2014 Jul 24. doi: 10.1038/srep05812
PMCID:
PMC4108927
AbstractArticlePDF–1.4M
16.
A Role for PP1/NIPP1 in Steering Migration of Human Cancer Cells
Cristina Martin-Granados, Alan R. Prescott, Nele Van Dessel, Aleyde Van Eynde, Miguel Arocena, Izabela P. Klaska, Janina Görnemann, Monique Beullens, Mathieu Bollen, John V. Forrester, Colin D. McCaig
PLoS One. 2012; 7(7): e40769. Published online 2012 Jul 16. doi: 10.1371/journal.pone.0040769
PMCID:
PMC3397927
AbstractArticlePDF–2.5M
17.
Protein Phosphatase 1α Mediates Ceramide-induced ERM Protein Dephosphorylation: A NOVEL MECHANISM INDEPENDENT OF PHOSPHATIDYLINOSITOL 4, 5-BIPHOSPHATE (PIP2) AND MYOSIN/ERM PHOSPHATASE
Daniel Canals, Patrick Roddy, Yusuf A. Hannun
J Biol Chem. 2012 Mar 23; 287(13): 10145–10155. Published online 2012 Feb 6. doi: 10.1074/jbc.M111.306456
PMCID:
PMC3323024
AbstractArticlePDF–3.0M
18.
PP1A-Mediated Dephosphorylation Positively Regulates YAP2 Activity
Pei Wang, Yujie Bai, Bangrong Song, Yadong Wang, Dong Liu, Yongqiang Lai, Xiaolin Bi, Zengqiang Yuan
PLoS One. 2011; 6(9): e24288. Published online 2011 Sep 1. doi: 10.1371/journal.pone.0024288
PMCID:
PMC3164728
AbstractArticlePDF–761K
19.
Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1
Marina Jerebtsova, Sergei A. Klotchenko, Tatiana O. Artamonova, Tatiana Ammosova, Kareem Washington, Vladimir V. Egorov, Aram A. Shaldzhyan, Maria V. Sergeeva, Evgeny A. Zatulovskiy, Olga A. Temkina, Mikhail G. Petukhov, Andrei V. Vasin, Mikhail A. Khodorkovskii, Yuri N. Orlov, Sergei Nekhai
Mol Cell Biochem. Author manuscript; available in PMC 2012 Jan 1.
Published in final edited form as: Mol Cell Biochem. 2011 Jan; 347(1-2): 79–87. Published online 2010 Oct 13. doi: 10.1007/s11010-010-0614-3
PMCID:
PMC3070240
AbstractArticlePDF–1.2M
20.
Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators
Joseph A. Marsh, Barbara Dancheck, Michael J. Ragusa, Marc Allaire, Julie D. Forman-Kay, Wolfgang Peti
Structure. Author manuscript; available in PMC 2011 Sep 8.
Published in final edited form as: Structure. 2010 Sep 8; 18(9): 1094–1103. doi: 10.1016/j.str.2010.05.015
PMCID:
PMC2936704
AbstractArticlePDF–1.8M

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