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Select item 110227211.

Kinome‐Wide Synthetic Lethal Screen Identifies PANK4 as a Modulator of Temozolomide Resistance in Glioblastoma

Viviana Vella, Angeliki Ditsiou, Anna Chalari, Murat Eravci, Sarah K. Wooller, Teresa Gagliano, Cecilia Bani, Emanuela Kerschbamer, Christos Karakostas, Bin Xu, Yongchang Zhang, Frances M.G. Pearl, Gianluca Lopez, Ling Peng, Justin Stebbing, Apostolos Klinakis, Georgios Giamas

Adv Sci (Weinh) 2024 Apr; 11(15): 2306027. Published online 2024 Feb 14. doi: 10.1002/advs.202306027

PMCID:: PMC11022721

Abstract Article PDF–34M

Select item 65117462.

Human pantothenate kinase 4 is a pseudo‐pantothenate kinase

Jiangwei Yao, Chitra Subramanian, Charles O. Rock, Suzanne Jackowski

Protein Sci. 2019 Jun; 28(6): 1031–1047. Published online 2019 Apr 17. doi: 10.1002/pro.3611

PMCID:: PMC6511746

Abstract Article PDF–6.0M

Select item 24949103.

Characterization of a Novel Cardiac Isoform of the Cell Cycle-related Kinase That Is Regulated during Heart Failure

Hongyu Qiu, Huacheng Dai, Komal Jain, Rina Shah, Chull Hong, Jayashree Pain, Bin Tian, Dorothy E. Vatner, Stephen F. Vatner, Christophe Depre

J Biol Chem. 2008 Aug 8; 283(32): 22157–22165. doi: 10.1074/jbc.M710459200

PMCID:: PMC2494910

Abstract Article PDF–515K

Select item 82925274.

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu

Nat Commun. 2021; 12: 4413. Published online 2021 Jul 20. doi: 10.1038/s41467-021-24703-7

PMCID:: PMC8292527

Abstract Article PDF–6.5M

Select item 65268685.

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies

Mansour Haidar, Bob Asselbergh, Elias Adriaenssens, Vicky De Winter, Jean-Pierre Timmermans, Michaela Auer-Grumbach, Manisha Juneja, Vincent Timmerman

Autophagy. 2019; 15(6): 1051–1068. Published online 2019 Jan 31. doi: 10.1080/15548627.2019.1569930

PMCID:: PMC6526868

Abstract Article PDF–4.0M

Select item 70015806.

A family of metal-dependent phosphatases implicated in metabolite damage-control

Lili Huang, Anna Khusnutdinova, Boguslaw Nocek, Greg Brown, Xiaohui Xu, Hong Cui, Pierre Petit, Robert Flick, Rémi Zallot, Kelly Balmant, Michael J Ziemak, John Shanklin, Valérie de Crécy-Lagard, Oliver Fiehn, Jesse F Gregory, III, Andrzej Joachimiak, Alexei Savchenko, Alexander F Yakunin, Andrew D Hanson

Nat Chem Biol. Author manuscript; available in PMC 2020 Feb 5.

Published in final edited form as: Nat Chem Biol. 2016 Aug; 12(8): 621–627. Published online 2016 Jun 20. doi: 10.1038/nchembio.2108

PMCID:: PMC7001580

Abstract Article PDF–1.9M

Select item 40831067.

Proteomic Analysis of the Epidermal Growth Factor Receptor (EGFR) Interactome and Post-translational Modifications Associated with Receptor Endocytosis in Response to EGF and Stress

Jiefei Tong, Paul Taylor, Michael F. Moran

Mol Cell Proteomics. 2014 Jul; 13(7): 1644–1658. Published online 2014 May 5. doi: 10.1074/mcp.M114.038596

PMCID:: PMC4083106

Abstract Article PDF–2.6M

Select item 94754628.

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold

Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo

Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134

PMCID:: PMC9475462

Abstract Article PDF–4.6M

Select item 88570499.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 889438010.

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing

Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl

Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2

PMCID:: PMC8894380

Abstract Article PDF–5.6M

Select item 430501511.

Global mapping of herpesvirus-host protein complexes reveals a novel transcription strategy for late genes

Zoe H. Davis, Erik Verschueren, Gwendolyn M. Jang, Kevin Kleffman, Jeffrey R. Johnson, Jimin Park, John Von Dollen, M. Cyrus Maher, Tasha Johnson, William Newton, Stefanie Jäger, Michael Shales, Julie Horner, Ryan D. Hernandez, Nevan J. Krogan, Britt A. Glaunsinger

Mol Cell. Author manuscript; available in PMC 2016 Jan 22.

Published in final edited form as: Mol Cell. 2015 Jan 22; 57(2): 349–360. Published online 2014 Dec 24. doi: 10.1016/j.molcel.2014.11.026

PMCID:: PMC4305015

Abstract Article PDF–1.9M

Select item 995018312.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 797970513.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

Select item 352258714.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 433215015.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 694204416.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 903609217.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

Select item 395408118.

A high-throughput approach for measuring temporal changes in the interactome

Anders R. Kristensen, Joerg Gsponer, Leonard J. Foster

Nat Methods. Author manuscript; available in PMC 2014 Mar 14.

Published in final edited form as: Nat Methods. 2012 Sep; 9(9): 907–909. Published online 2012 Aug 5. doi: 10.1038/nmeth.2131

PMCID:: PMC3954081

Abstract Article PDF–632K

Select item 549522519.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 905883620.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

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