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Items: 1 to 20 of 74

1.
PRKAR2B plays an oncogenic role in the castration-resistant prostate cancer
Jianjun Sha, Wei Xue, Baijun Dong, Jiahua Pan, Xiaorong WU, Dong Li, Dongming Liu, Yiran Huang
Oncotarget. 2017 Jan 24; 8(4): 6114–6129. Published online 2016 Dec 20. doi: 10.18632/oncotarget.14044
PMCID:
PMC5351617
AbstractArticlePDF–3.9M
2.
Protein Kinase A (PKA) Isoform RIIβ Mediates the Synergistic Killing Effect of cAMP and Glucocorticoid in Acute Lymphoblastic Leukemia Cells
Zhenyu Ji, Fang C. Mei, Aaron L. Miller, E. Brad Thompson, Xiaodong Cheng
J Biol Chem. 2008 Aug 8; 283(32): 21920–21925. doi: 10.1074/jbc.M803193200
PMCID:
PMC2494930
AbstractArticlePDF–327K
3.
Identification of a high affinity binding protein for the regulatory subunit RII beta of cAMP-dependent protein kinase in Golgi enriched membranes of human lymphoblasts.
R M Rios, C Celati, S M Lohmann, M Bornens, G Keryer
EMBO J. 1992 May; 11(5): 1723–1731. doi: 10.1002/j.1460-2075.1992.tb05224.x
PMCID:
PMC556630
SummaryPage BrowsePDF–2.0M
4.
An antisense oligodeoxynucleotide targeted against the type II beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects.
G Tortora, T Clair, Y S Cho-Chung
Proc Natl Acad Sci U S A. 1990 Jan; 87(2): 705–708. doi: 10.1073/pnas.87.2.705
PMCID:
PMC53334
SummaryPage BrowsePDF–1.0M
5.
Phosphorylation of the regulatory subunit of type II beta cAMP-dependent protein kinase by cyclin B/p34cdc2 kinase impairs its binding to microtubule-associated protein 2.
G Keryer, Z Luo, J C Cavadore, J Erlichman, M Bornens
Proc Natl Acad Sci U S A. 1993 Jun 15; 90(12): 5418–5422. doi: 10.1073/pnas.90.12.5418
PMCID:
PMC46731
SummaryPage BrowsePDF–1.4M
6.
Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts.
A Budillon, A Cereseto, A Kondrashin, M Nesterova, G Merlo, T Clair, Y S Cho-Chung
Proc Natl Acad Sci U S A. 1995 Nov 7; 92(23): 10634–10638. doi: 10.1073/pnas.92.23.10634
PMCID:
PMC40666
SummaryPage BrowsePDF–1.5M
7.
PRKAR2B‐HIF‐1α loop promotes aerobic glycolysis and tumour growth in prostate cancer
Lei Xia, Jian Sun, Shaowei Xie, Chenfei Chi, Yinjie Zhu, Jiahua Pan, Baijun Dong, Yiran Huang, Weiliang Xia, Jianjun Sha, Wei Xue
Cell Prolif. 2020; 53(11): e12918. Published online 2020 Oct 7. doi: 10.1111/cpr.12918
PMCID:
PMC7653268
AbstractArticlePDF–2.1M
8.
Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription
Kristin Lucia, Yonghe Wu, Jose Monteserin Garcia, Anne Barlier, Michael Buchfelder, Wolfgang Saeger, Ulrich Renner, Günter K. Stalla, Marily Theodoropoulou
Oncogene. 2020; 39(16): 3367–3380. Published online 2020 Feb 28. doi: 10.1038/s41388-020-1223-6
PMCID:
PMC7160059
AbstractArticlePDF–981K
9.
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
Tsan-Wen Lu, Jian Wu, Phillip C. Aoto, Jui-Hung Weng, Lalima G. Ahuja, Nicholas Sun, Cecilia Y. Cheng, Ping Zhang, Susan S. Taylor
Proc Natl Acad Sci U S A. 2019 Aug 13; 116(33): 16347–16356. Published online 2019 Jul 30. doi: 10.1073/pnas.1906036116
PMCID:
PMC6697891
AbstractArticlePDF–1.8M
10.
Differential expression of the protein kinase A subunits in normal adrenal glands and adrenocortical adenomas
Isabel Weigand, Cristina L. Ronchi, Marthe Rizk-Rabin, Guido Di Dalmazi, Vanessa Wild, Kerstin Bathon, Beatrice Rubin, Davide Calebiro, Felix Beuschlein, Jérôme Bertherat, Martin Fassnacht, Silviu Sbiera
Sci Rep. 2017; 7: 49. Published online 2017 Mar 13. doi: 10.1038/s41598-017-00125-8
PMCID:
PMC5427838
AbstractArticlePDF–5.8M
11.
Comparison of the Effects of PRKAR1A and PRKAR2B Depletion on Signaling Pathways, Cell Growth, and Cell Cycle Control of Adrenocortical Cells
F. Basso, F. Rocchetti, S. Rodriguez, M. Nesterova, F. Cormier, C. Stratakis, B. Ragazzon, J. Bertherat, M. Rizk-Rabin
Horm Metab Res. Author manuscript; available in PMC 2016 Jan 26.
Published in final edited form as: Horm Metab Res. 2014 Nov; 46(12): 883–888. Published online 2014 Sep 30. doi: 10.1055/s-0034-1389951
PMCID:
PMC4727442
AbstractArticlePDF–610K
12.
Plasmin Overcomes Resistance to Prostaglandin E2 in Fibrotic Lung Fibroblasts by Reorganizing Protein Kinase A Signaling
Katsuhide Okunishi, Thomas H. Sisson, Steven K. Huang, Cory M. Hogaboam, Richard H. Simon, Marc Peters-Golden
J Biol Chem. 2011 Sep 16; 286(37): 32231–32243. Published online 2011 Jul 27. doi: 10.1074/jbc.M111.235606
PMCID:
PMC3173171
AbstractArticlePDF–4.6M
13.
Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis.
P Scambler, O Oyen, B Wainwright, M Farrall, H Y Law, X Estivill, M Sandberg, R Williamson, T Jahnsen
Am J Hum Genet. 1987 Nov; 41(5): 925–932.
PMCID:
PMC1684338
SummaryPage BrowsePDF–1018K
14.
Compartmentalization of protein kinase A signaling by the heterotrimeric G protein Go
Sungho Ghil, Jung-Mi Choi, Sung-Soo Kim, Young-Don Lee, Yanhong Liao, Lutz Birnbaumer, Haeyoung Suh-Kim
Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50): 19158–19163. Published online 2006 Dec 5. doi: 10.1073/pnas.0609392103
PMCID:
PMC1682014
AbstractArticlePDF–1.3M
15.
Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome
Adrian Palencia-Campos, Phillip C. Aoto, Erik M.F. Machal, Ana Rivera-Barahona, Patricia Soto-Bielicka, Daniela Bertinetti, Blaine Baker, Lily Vu, Francesca Piceci-Sparascio, Isabella Torrente, Eveline Boudin, Silke Peeters, Wim Van Hul, Celine Huber, Dominique Bonneau, Michael S. Hildebrand, Matthew Coleman, Melanie Bahlo, Mark F. Bennett, Amy L. Schneider, Ingrid E. Scheffer, Maria Kibæk, Britta S. Kristiansen, Mahmoud Y. Issa, Mennat I. Mehrez, Samira Ismail, Jair Tenorio, Gaoyang Li, Bjørn Steen Skålhegg, Ghada A. Otaify, Samia Temtamy, Mona Aglan, Aia E. Jønch, Alessandro De Luca, Geert Mortier, Valérie Cormier-Daire, Alban Ziegler, Mathew Wallis, Pablo Lapunzina, Friedrich W. Herberg, Susan S. Taylor, Victor L. Ruiz-Perez
Am J Hum Genet. 2020 Nov 5; 107(5): 977–988. Published online 2020 Oct 14. doi: 10.1016/j.ajhg.2020.09.005
PMCID:
PMC7675002
AbstractArticlePDF–3.0M
16.
Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme
Ping Zhang, Matthias J. Knape, Lalima G. Ahuja, Malik M. Keshwani, Charles C. King, Mira Sastri, Friedrich W. Herberg, Susan S. Taylor
PLoS Biol. 2015 Jul; 13(7): e1002192. Published online 2015 Jul 9. doi: 10.1371/journal.pbio.1002192
PMCID:
PMC4497662
AbstractArticlePDF–3.0M
17.
cAMP-dependent Protein Kinase A (PKA) Signaling Induces TNFR1 Exosome-like Vesicle Release via Anchoring of PKA Regulatory Subunit RIIβ to BIG2
Aminul Islam, Heather Jones, Toyoko Hiroi, Jonathan Lam, Jing Zhang, Joel Moss, Martha Vaughan, Stewart J. Levine
J Biol Chem. 2008 Sep 12; 283(37): 25364–25371. doi: 10.1074/jbc.M804966200
PMCID:
PMC2533074
AbstractArticlePDF–398K
18.
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
Evangelos Evangelou, Ana M. Valdes, Hanneke J.M Kerkhof, Unnur Styrkarsdottir, YanYan Zhu, Ingrid Meulenbelt, Rik J. Lories, Fotini B. Karassa, Przemko Tylzanowski, Steffan D. Bos, arcOGEN consortium, Toru Akune, Nigel K. Arden, Andrew Carr, Kay Chapman, L. Adrienne Cupples, Jin Dai, Panos Deloukas, Michael Doherty, Sally Doherty, Gunnar Engstrom, Antonio Gonzalez, Bjarni V. Halldorsson, Christina L. Hammond, Deborah J. Hart, Hafdis Helgadottir, Albert Hofman, Shiro Ikegawa, Thorvaldur Ingvarsson, Qing Jiang, Helgi Jonsson, Jaakko Kaprio, Hiroshi Kawaguchi, Kalle Kisand, Margreet Kloppenburg, Urho M. Kujala, L. Stefan Lohmander, John Loughlin, Frank P. Luyten, Akihiko Mabuchi, Andrew McCaskie, Masahiro Nakajima, Peter M. Nilsson, Nao Nishida, William E.R. Ollier, Kalliope Panoutsopoulou, Tom van de Putte, Stuart H. Ralston, Fernado Rivadeneira, Janna Saarela, Stefan Schulte-Merker, P. Eline Slagboom, Akihiro Sudo, Agu Tamm, Ann Tamm, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Aspasia Tsezou, Gillian A. Wallis, J. Mark Wilkinson, Noriko Yoshimura, Eleftheria Zeggini, Guangju Zhai, Feng Zhang, Ingileif Jonsdottir, Andre G. Uitterlinden, David T Felson, Joyce B. van Meurs, Kari Stefansson, John P.A. Ioannidis, Timothy D. Spector
Ann Rheum Dis. Author manuscript; available in PMC 2013 Apr 3.
Published in final edited form as: Ann Rheum Dis. 2011 Feb; 70(2): 349–355. Published online 2010 Nov 10. doi: 10.1136/ard.2010.132787
PMCID:
PMC3615180
AbstractArticlePDF–624K
19.
PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades
Eduard Stefan, Mohan K. Malleshaiah, Billy Breton, Po Hien Ear, Verena Bachmann, Michael Beyermann, Michel Bouvier, Stephen W. Michnick
Nat Commun. 2011 Dec 20; 2: 598. Published online 2011 Dec 20. doi: 10.1038/ncomms1605
PMCID:
PMC3247815
AbstractArticlePDF–758K
20.
D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain
Lily Jun-shen Huang, Kyle Durick, Joshua A. Weiner, Jerold Chun, Susan S. Taylor
Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21): 11184–11189. doi: 10.1073/pnas.94.21.11184
PMCID:
PMC23409
AbstractArticlePDF–512K

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