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Select item 64008991.

Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB

Bidhan Sarkar, Ichiro Nishikata, Shingo Nakahata, Tomonaga Ichikawa, Toshiyuki Shiraga, Hasi Rani Saha, Masahiro Fujii, Yuetsu Tanaka, Kazuya Shimoda, Kazuhiro Morishita

Sci Rep. 2019; 9: 3491. Published online 2019 Mar 5. doi: 10.1038/s41598-019-39424-7

PMCID:: PMC6400899

Abstract Article PDF–2.4M

Select item 92084492.

Translocator protein (18 kDa) regulates the microglial phenotype in Parkinson’s disease through P47

Xue Xue, Rui Duan, Guoyan Zheng, Hucheng Chen, Weiwei Zhang, Liang Shi

Bioengineered. 2022; 13(4): 11061–11071. Published online 2022 Apr 27. doi: 10.1080/21655979.2022.2068754

PMCID:: PMC9208449

Abstract Article PDF–2.2M

Select item 80908563.

p97 and p47 function in membrane tethering in cooperation with FTCD during mitotic Golgi reassembly

Yayoi Kaneko, Kyohei Shimoda, Rafael Ayala, Yukina Goto, Silvia Panico, Xiaodong Zhang, Hisao Kondo

EMBO J. 2021 May 3; 40(9): e105853. Published online 2021 Feb 8. doi: 10.15252/embj.2020105853

PMCID:: PMC8090856

Abstract Article PDF–3.3M

Select item 43943164.

Altered cofactor regulation with disease-associated p97/VCP mutations

Xiaoyi Zhang, Lin Gui, Xiaoyan Zhang, Stacie L. Bulfer, Valentina Sanghez, Daniel E. Wong, YouJin Lee, Lynn Lehmann, James Siho Lee, Pei-Yin Shih, Henry J. Lin, Michelina Iacovino, Conrad C. Weihl, Michelle R. Arkin, Yanzhuang Wang, Tsui-Fen Chou

Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1705–E1714. Published online 2015 Mar 16. doi: 10.1073/pnas.1418820112

PMCID:: PMC4394316

Abstract Article PDF–1.5M

Select item 111591005.

Critical roles of T‐LAK cell‐originated protein kinase in cytokinesis

Jae‐Hyun Park, Toshihiko Nishidate, Yusuke Nakamura, Toyomasa Katagiri

Cancer Sci. 2010 Feb; 101(2): 403–411. Published online 2009 Oct 12. doi: 10.1111/j.1349-7006.2009.01400.x

PMCID:: PMC11159100

Abstract Article PDF–939K

Select item 90585396.

K27‐linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation

Robert F Shearer, Dimitris Typas, Fabian Coscia, Sofie Schovsbo, Thomas Kruse, Andreas Mund, Niels Mailand

EMBO J. 2022 May; 41(9): e110145. Published online 2022 Mar 29. doi: 10.15252/embj.2021110145

PMCID:: PMC9058539

Abstract Article PDF–2.9M

Select item 31742427.

The Tissue-Specific Rep8/UBXD6 Tethers p97 to the Endoplasmic Reticulum Membrane for Degradation of Misfolded Proteins

Louise Madsen, Franziska Kriegenburg, Andrea Vala, Diana Best, Søren Prag, Kay Hofmann, Michael Seeger, Ian R. Adams, Rasmus Hartmann-Petersen

PLoS One. 2011; 6(9): e25061. Published online 2011 Sep 15. doi: 10.1371/journal.pone.0025061

PMCID:: PMC3174242

Abstract Article PDF–3.8M

Select item 49331908.

Pathogenic Mutations in the Valosin-containing Protein/p97(VCP) N-domain Inhibit the SUMOylation of VCP and Lead to Impaired Stress Response

Tao Wang, Wangchao Xu, Meiling Qin, Yi Yang, Puhua Bao, Fuxiao Shen, Zhenlin Zhang, Jin Xu

J Biol Chem. 2016 Jul 1; 291(27): 14373–14384. Published online 2016 May 13. doi: 10.1074/jbc.M116.729343

PMCID:: PMC4933190

Abstract Article PDF–2.9M

Select item 21730059.

The localization and phosphorylation of p47 are important for Golgi disassembly–assembly during the cell cycle

Keiji Uchiyama, Eija Jokitalo, Mervi Lindman, Mark Jackman, Fumi Kano, Masayuki Murata, Xiaodong Zhang, Hisao Kondo

J Cell Biol. 2003 Jun 23; 161(6): 1067–1079. doi: 10.1083/jcb.200303048

PMCID:: PMC2173005

Abstract Article PDF–665K

Select item 145693910.

Conformational changes in the AAA ATPase p97–p47 adaptor complex

Fabienne Beuron, Ingrid Dreveny, Xuemei Yuan, Valerie E Pye, Ciaran Mckeown, Louise C Briggs, Matthew J Cliff, Yayoi Kaneko, Russell Wallis, Rivka L Isaacson, John E Ladbury, Steve J Matthews, Hisao Kondo, Xiaodong Zhang, Paul S Freemont

EMBO J. 2006 May 3; 25(9): 1967–1976. Published online 2006 Apr 6. doi: 10.1038/sj.emboj.7601055

PMCID:: PMC1456939

Abstract Article PDF–430K

Select item 322598611.

Valosin-containing protein and neurofibromin interact to regulate dendritic spine density

Hsiao-Fang Wang, Yu-Tzu Shih, Chiung-Ya Chen, Hsu-Wen Chao, Ming-Jen Lee, Yi-Ping Hsueh

J Clin Invest. 2011 Dec 1; 121(12): 4820–4837. Published online 2011 Nov 21. doi: 10.1172/JCI45677

PMCID:: PMC3225986

Abstract Article PDF–4.9M

Select item 289232412.

Imbalances in p97 co-factor interactions in human proteinopathy

Vanesa Fernández-Sáiz, Alexander Buchberger

EMBO Rep. 2010 Jun; 11(6): 479–485. Published online 2010 Apr 23. doi: 10.1038/embor.2010.49

PMCID:: PMC2892324

Abstract Article PDF–849K

Select item 217338613.

VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo

Keiji Uchiyama, Eija Jokitalo, Fumi Kano, Masayuki Murata, Xiaodong Zhang, Benito Canas, Richard Newman, Catherine Rabouille, Darryl Pappin, Paul Freemont, Hisao Kondo

J Cell Biol. 2002 Dec 9; 159(5): 855–866. doi: 10.1083/jcb.200208112

PMCID:: PMC2173386

Abstract Article PDF–640K

Select item 637740614.

PINK1 Interacts with VCP/p97 and Activates PKA to Promote NSFL1C/p47 Phosphorylation and Dendritic Arborization in Neurons

Kent Z. Q. Wang, Erin Steer, P. Anthony Otero, Nicholas W. Bateman, Mary Hongying Cheng, Ana Ligia Scott, Christine Wu, Ivet Bahar, Yu-Tzu Shih, Yi-Ping Hsueh, Charleen T. Chu

eNeuro. 2018 Nov-Dec; 5(6): ENEURO.0466-18.2018. Prepublished online 2018 Dec 19. Published online 2018 Jan 10. doi: 10.1523/ENEURO.0466-18.2018

PMCID:: PMC6377406

Abstract Article PDF–3.0M

Select item 514408015.

GSK-3β controls NF-kappaB activity via IKKγ/NEMO

Senad Medunjanin, Lisa Schleithoff, Christian Fiegehenn, Soenke Weinert, Werner Zuschratter, Ruediger C. Braun-Dullaeus

Sci Rep. 2016; 6: 38553. Published online 2016 Dec 8. doi: 10.1038/srep38553

PMCID:: PMC5144080

Abstract Article PDF–1.3M

Select item 494281116.

Monoubiquitination of syntaxin 5 regulates Golgi membrane dynamics during the cell cycle

Shijiao Huang, Danming Tang, Yanzhuang Wang

Dev Cell. Author manuscript; available in PMC 2017 Jul 11.

Published in final edited form as: Dev Cell. 2016 Jul 11; 38(1): 73–85. doi: 10.1016/j.devcel.2016.06.001

PMCID:: PMC4942811

Abstract Article PDF–2.4M

Select item 521986017.

VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington’s disease

Xing Guo, Xin Qi

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Feb; 1863(2): 552–559. Published online 2016 Nov 29. doi: 10.1016/j.bbadis.2016.11.026

PMCID:: PMC5219860

Abstract Article PDF–2.5M

Select item 412449418.

Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect

Louise Madsen, Karen Molbæk, Ida B Larsen, Sofie V Nielsen, Esben G Poulsen, Peter S Walmod, Kay Hofmann, Michael Seeger, Chen-Ying Chien, Rey-Huei Chen, Franziska Kriegenburg, Rasmus Hartmann-Petersen

BMC Cell Biol. 2014; 15: 31. Published online 2014 Jul 31. doi: 10.1186/1471-2121-15-31

PMCID:: PMC4124494

Abstract Article PDF–2.6M

Select item 13107619.

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1–Npl4

Hemmo H. Meyer, Yanzhuang Wang, Graham Warren

EMBO J. 2002 Nov 1; 21(21): 5645–5652. doi: 10.1093/emboj/cdf579

PMCID:: PMC131076

Abstract Article PDF–255K

Select item 365336220.

The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A

Elsa Kress, Françoise Schwager, René Holtackers, Jonas Seiler, François Prodon, Esther Zanin, Annika Eiteneuer, Mika Toya, Asako Sugimoto, Hemmo Meyer, Patrick Meraldi, Monica Gotta

J Cell Biol. 2013 May 13; 201(4): 559–575. doi: 10.1083/jcb.201209107