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Select item 111358761.

Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation

Karolina Pierzynowska, Magdalena Podlacha, Lidia Gaffke, Estera Rintz, Karolina Wiśniewska, Zuzanna Cyske, Grzegorz Węgrzyn

Autophagy. 2024; 20(5): 1159–1182. Published online 2023 Nov 22. doi: 10.1080/15548627.2023.2286116

PMCID:: PMC11135876

Abstract Article PDF–3.6M

Select item 110727252.

Pregnancy-induced physiological hypertrophic preconditioning attenuates pathological myocardial hypertrophy by activation of FoxO3a

Jiahe Xie, Cankun Zheng, Mengjia Shen, Weiling Lu, Mingjue Li, Mingyuan He, Lu Chen, Siyuan Ma, Yingqi Zhu, Hairuo Lin, Jiancheng Xiu, Wangjun Liao, Jianping Bin, Yulin Liao

Cell Mol Life Sci. 2023 Sep; 80(9): 267. Published online 2023 Aug 26. doi: 10.1007/s00018-023-04909-2

PMCID:: PMC11072725

Abstract Article PDF–2.6M

Select item 110289103.

FOXO3, estrogen receptor alpha, and androgen receptor impact tumor growth rate and infiltration of dendritic cell subsets differentially between male and female mice

Matthew G. Thompson, Daniel S. Peiffer, Michelle Larson, Flor Navarro, Stephanie K. Watkins

Cancer Immunol Immunother. 2017 May; 66(5): 615–625. Published online 2017 Feb 22. doi: 10.1007/s00262-017-1972-4

PMCID:: PMC11028910

Abstract Article PDF–1.6M

Select item 105630864.

FoxO3 Modulates Circadian Rhythms in Neural Stem Cells

Swip Draijer, Raissa Timmerman, Jesse Pannekeet, Alexandra van Harten, Elham Aida Farshadi, Julius Kemmer, Demy van Gilst, Inês Chaves, Marco F. M. Hoekman

Int J Mol Sci. 2023 Sep; 24(17): 13662. Published online 2023 Sep 4. doi: 10.3390/ijms241713662

PMCID:: PMC10563086

Abstract Article PDF–3.8M

Select item 103187945.

Downregulation of circ-Foxo3 in breast cancer stem-like cells

Mohammad Kamalabadi-Farahani, Amir Atashi, Mohammad Masoud Eslami

BMC Res Notes. 2023; 16: 132. Published online 2023 Jul 3. doi: 10.1186/s13104-023-06405-z

PMCID:: PMC10318794

Abstract Article PDF–1.0M

Select item 100503966.

Mitochondria-derived H₂O₂ triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice

Hua Bai, Cong-Wen Fang, Ying Shi, Song Zhai, An Jiang, Ying-Na Li, Lin Wang, Qi-Ling Liu, Geng-Yao Zhou, Jia-Hao Cao, Jia Li, Xue-Kang Yang, Xu-Jun Qin

Cell Death Dis. 2023 Mar; 14(3): 216. Published online 2023 Mar 28. doi: 10.1038/s41419-023-05744-w

PMCID:: PMC10050396

Abstract Article PDF–5.3M

Select item 96406107.

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy

Chen Zhao, Xiaodong Li, Guantong Sun, Pengcheng Liu, Keyu Kong, Xuzhuo Chen, Fei Yang, Xiaoqing Wang

Cell Death Dis. 2022 Nov; 13(11): 932. Published online 2022 Nov 7. doi: 10.1038/s41419-022-05390-8

PMCID:: PMC9640610

Abstract Article PDF–6.6M

Select item 85973108.

Knockdown of circFOXO3 ameliorates cigarette smoke-induced lung injury in mice

Lei Zhou, Bo Wu, Jun Yang, Bing Wang, Jing Pan, Donghui Xu, Chunling Du

Respir Res. 2021; 22: 294. Published online 2021 Nov 17. doi: 10.1186/s12931-021-01883-w

PMCID:: PMC8597310

Abstract Article PDF–4.7M

Select item 84928699.

C. D. Rollo, S. E. Marsh-Rollo, D. Boreham, J. A. Lemon

GeroScience. 2021 Aug; 43(4): 1935–1946. Published online 2021 Apr 17. doi: 10.1007/s11357-021-00364-8

PMCID:: PMC8492869

Abstract Article PDF–529K

Select item 837336610.

FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology

Shuqi Du, Feng Jin, Laure Maneix, Manasee Gedam, Yin Xu, Andre Catic, Meng C. Wang, Hui Zheng

Aging Cell. 2021 Aug; 20(8): e13432. Published online 2021 Jul 11. doi: 10.1111/acel.13432

PMCID:: PMC8373366

Abstract Article PDF–3.1M

Select item 826361011.

Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice

Holly J. Beaulac, Felicia Gilels, Jingyuan Zhang, Sarah Jeoung, Patricia M. White

Cell Death Dis. 2021 Jul; 12(7): 682. Published online 2021 Jul 7. doi: 10.1038/s41419-021-03972-6

PMCID:: PMC8263610

Abstract Article PDF–5.4M

Select item 784364512.

Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification

Inah Hwang, Hiroki Uchida, Ziwei Dai, Fei Li, Teresa Sanchez, Jason W. Locasale, Lewis C. Cantley, Hongwu Zheng, Jihye Paik

Nat Commun. 2021; 12: 640. Published online 2021 Jan 28. doi: 10.1038/s41467-020-20839-0

PMCID:: PMC7843645

Abstract Article PDF–2.0M

Select item 705694013.

Hypoxia induces the dormant state in oocytes through expression of Foxo3

So Shimamoto, Yohei Nishimura, Go Nagamatsu, Norio Hamada, Haruka Kita, Orie Hikabe, Nobuhiko Hamazaki, Katsuhiko Hayashi

Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12321–12326. Published online 2019 May 30. doi: 10.1073/pnas.1817223116

PMCID:: PMC7056940

Abstract Article PDF–1.8M

Select item 697139414.

Spermidine Suppresses Inflammatory DC Function by Activating the FOXO3 Pathway and Counteracts Autoimmunity

Guanhua Li, Huihua Ding, Xiang Yu, Yao Meng, Jun Li, Qiang Guo, Haibo Zhou, Nan Shen

iScience. 2020 Jan 24; 23(1): 100807. Published online 2019 Dec 27. doi: 10.1016/j.isci.2019.100807

PMCID:: PMC6971394

Abstract Article PDF–5.8M

Select item 685693815.

Forkhead transcription factor FOXO3a mediates interferon‐γ‐induced MHC II transcription in macrophages

Xiaoyan Wu, Zhiwen Fan, Ming Chen, Yi Chen, Danyan Rong, Zhiwei Cui, Yibiao Yuan, Lili Zhuo, Yong Xu

Immunology. 2019 Dec; 158(4): 304–313. Published online 2019 Oct 3. doi: 10.1111/imm.13116

PMCID:: PMC6856938

Abstract Article PDF–880K

Select item 671855216.

Forkhead box O3 protects the heart against paraquat‐induced aging‐associated phenotypes by upregulating the expression of antioxidant enzymes

Zao‐Shang Chang, Jing‐Bo Xia, Hai‐Yan Wu, Wen‐Tao Peng, Fu‐Qing Jiang, Jing Li, Chi‐Qian Liang, Hui Zhao, Kyu‐Sang Park, Guo‐Hua Song, Soo‐Ki Kim, Ruijin Huang, Li Zheng, Dong‐Qing Cai, Xu‐Feng Qi

Aging Cell. 2019 Oct; 18(5): e12990. Published online 2019 Jul 1. doi: 10.1111/acel.12990

PMCID:: PMC6718552

Abstract Article PDF–2.9M

Select item 661880917.

Mutation of Foxo3 Causes Adult Onset Auditory Neuropathy and Alters Cochlear Synapse Architecture in Mice

Felicia Gilels, Stephen T. Paquette, Jingyuan Zhang, Irfan Rahman, Patricia M. White

J Neurosci. 2013 Nov 20; 33(47): 18409–18424. doi: 10.1523/JNEUROSCI.2529-13.2013

PMCID:: PMC6618809

Abstract Article PDF–6.8M

Select item 647834618.

FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells

Amanda J. Audesse, Shleshma Dhakal, Lexi-Amber Hassell, Zachary Gardell, Yuliya Nemtsova, Ashley E. Webb

PLoS Genet. 2019 Apr; 15(4): e1008097. Published online 2019 Apr 11. doi: 10.1371/journal.pgen.1008097

PMCID:: PMC6478346

Abstract Article PDF–3.6M

Select item 605782119.

Foxo3 promotes apoptosis of BCR-stimulated immature B cells, thus limiting the window for receptor editing

Kristina Ottens, Rochelle M. Hinman, Evan Barrios, Brian Skaug, Laurie S. Davis, Quan-Zhen Li, Diego H. Castrillon, Anne B. Satterthwaite

J Immunol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Immunol. 2018 Aug 1; 201(3): 940–949. Published online 2018 Jun 27. doi: 10.4049/jimmunol.1701070

PMCID:: PMC6057821

Abstract Article PDF–760K

Select item 580151320.

FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis

Hamza M Al‐Tamari, Swati Dabral, Anja Schmall, Pouya Sarvari, Clemens Ruppert, Jihye Paik, Ronald A DePinho, Friedrich Grimminger, Oliver Eickelberg, Andreas Guenther, Werner Seeger, Rajkumar Savai, Soni S Pullamsetti

EMBO Mol Med. 2018 Feb; 10(2): 276–293. Published online 2017 Dec 7. doi: 10.15252/emmm.201606261