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Items: 1 to 20 of 238

1.
mTOR Inhibitors Modulate the Physical Properties of 3D Spheroids Derived from H9c2 Cells
Megumi Watanabe, Toshiyuki Yano, Tatsuya Sato, Araya Umetsu, Megumi Higashide, Masato Furuhashi, Hiroshi Ohguro
Int J Mol Sci. 2023 Jul; 24(14): 11459. Published online 2023 Jul 14. doi: 10.3390/ijms241411459
PMCID:
PMC10380298
AbstractArticlePDF–6.7M
2.
Vitamin B6 Deficiency Induces Autism-Like Behaviors in Rats by Regulating mTOR-Mediated Autophagy in the Hippocampus
Lijuan Chen, Jing Li, Xinglian Liu, Zhiwei Zhao, Yan Jin, Yikun Fu, Aiqin Zhou, Chengqun Wang, Yan Zhou
Behav Neurol. 2023; 2023: 6991826. Published online 2023 May 9. doi: 10.1155/2023/6991826
PMCID:
PMC10188270
AbstractArticlePDF–1.8M
3.
The Mechanism of Aerobic Exercise Regulating the PI3K/Akt-mTOR Signaling Pathway Intervenes in Hippocampal Neuronal Apoptosis in Vascular Dementia Rats
Lei Gao, Fushun Liu, Ruilian Liu
Int J Environ Res Public Health. 2023 Feb; 20(3): 1893. Published online 2023 Jan 19. doi: 10.3390/ijerph20031893
PMCID:
PMC9914742
AbstractArticlePDF–1.0M
4.
Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+-CaMKII-Dependent Akt/mTOR Pathway
RUIJIE ZHANG, YU ZHU, XIAOQING DONG, BEIBEI LIU, NANA ZHANG, XIAOXUE WANG, LEI LIU, CHONG XU, SHILE HUANG, LONG CHEN
J Cell Physiol. Author manuscript; available in PMC 2022 Jun 23.
Published in final edited form as: J Cell Physiol. 2017 Aug; 232(8): 2145–2157. Published online 2017 Feb 28. doi: 10.1002/jcp.25703
PMCID:
PMC9218942
AbstractArticlePDF–2.6M
5.
Hippocampal mTOR Dysregulation and Morphological Changes in Male Rats after Fetal Growth Restriction
Charlotte Schömig, Laura Oberholz, Gregor Fink, Jenny Voggel, Maria Wohlfarth, Jörg Dötsch, Kai-Dietrich Nüsken, Eva Nüsken
Nutrients. 2022 Feb; 14(3): 451. Published online 2022 Jan 20. doi: 10.3390/nu14030451
PMCID:
PMC8839133
AbstractArticlePDF–2.2M
6.
Exosomes Derived from M2 Macrophages Exert a Therapeutic Effect via Inhibition of the PI3K/AKT/mTOR Pathway in Rats with Knee Osteoarthritic
Zha Xi Da-wa, Ma Jun, Liu Chao-Zheng, Yang Sen-Lin, Lu Chuan, Li De-chun, Dong Zu-Nan, Zhao Hong-tao, Wei Shu-qing, Pei Xian-wei, Liu Wenbo, Li Ke-wen
Biomed Res Int. 2021; 2021: 7218067. Published online 2021 Dec 10. doi: 10.1155/2021/7218067
PMCID:
PMC8683166
AbstractArticlePDF–1.9M
7.
Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR–v-ATPase axis
Shujin Wang, Francesco Schianchi, Dietbert Neumann, Li-Yen Wong, Aomin Sun, Frans A. van Nieuwenhoven, Maurice P. Zeegers, Agnieszka Strzelecka, Umare Col, Jan F.C. Glatz, Miranda Nabben, Joost J.F.P. Luiken
Mol Metab. 2021 Nov; 53: 101293. Published online 2021 Jul 13. doi: 10.1016/j.molmet.2021.101293
PMCID:
PMC8350375
AbstractArticlePDF–3.1M
8.
Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway
Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Int J Mol Med. 2021 Mar; 47(3): 27. Published online 2021 Jan 27. doi: 10.3892/ijmm.2021.4860
PMCID:
PMC7895520
AbstractArticlePDF–980K
9.
Altered expression of activator proteins that control follicle reserve after ovarian tissue cryopreservation/transplantation and primordial follicle loss prevention by rapamycin
Soner Celik, Sinan Ozkavukcu, Ciler Celik-Ozenci
J Assist Reprod Genet. 2020 Sep; 37(9): 2119–2136. Published online 2020 Jul 10. doi: 10.1007/s10815-020-01875-7
PMCID:
PMC7492284
AbstractArticlePDF–42M
10.
Amino Acid–Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet
Scot R Kimball, Suhana Ravi, Bradley S Gordon, Michael D Dennis, Leonard S Jefferson
J Nutr. 2015 Nov; 145(11): 2496–2502. Published online 2015 Sep 23. doi: 10.3945/jn.115.215491
PMCID:
PMC7289329
AbstractArticlePDF–938K
11.
Ligustrazine ameliorates lipopolysaccharide-induced neurocognitive impairment by activating autophagy via the PI3K/AKT/mTOR pathway
Guangming Li, Sisi Liu, Huili Wang, Rui Pan, Haijie Tang, Xueqin Yan, Yanping Wang, Yongmei Fu, Fujun Jing, Jun Dong
Int J Mol Med. 2020 Jun; 45(6): 1711–1720. Published online 2020 Mar 20. doi: 10.3892/ijmm.2020.4548
PMCID:
PMC7169653
AbstractArticlePDF–902K
12.
Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways
Xin Li, Zuocheng Yang, Wenyuan Nie, Jie Jiang, Shentang Li, Zhuoying Li, Lang Tian, Xing Ma
Cell Death Dis. 2019 Oct; 10(10): 691. Published online 2019 Sep 18. doi: 10.1038/s41419-019-1910-9
PMCID:
PMC6751166
AbstractArticlePDF–3.8M
13.
Biphasic Activation of the mTOR Pathway in the Gustatory Cortex Is Correlated with and Necessary for Taste Learning
Katya Belelovsky, Hanoch Kaphzan, Alina Elkobi, Kobi Rosenblum
J Neurosci. 2009 Jun 10; 29(23): 7424–7431. doi: 10.1523/JNEUROSCI.3809-08.2009
PMCID:
PMC6665417
AbstractArticlePDF–1.0M
14.
Inhibition of mitochondrial autophagy protects donor lungs for lung transplantation against ischaemia‐reperfusion injury in rats via the mTOR pathway
Wei‐Cheng Liu, Shi‐Biao Chen, Sheng Liu, Xiang Ling, Qi‐Rong Xu, Ben‐Tong Yu, Jian Tang
J Cell Mol Med. 2019 May; 23(5): 3190–3201. Published online 2019 Mar 19. doi: 10.1111/jcmm.14177
PMCID:
PMC6484325
AbstractArticlePDF–1.4M
15.
Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production
T. M. Zaved Waise, Mozhgan Rasti, Frank A. Duca, Song-Yang Zhang, Paige V. Bauer, Christopher J. Rhodes, Tony K. T. Lam
Nat Commun. 2019; 10: 714. Published online 2019 Feb 12. doi: 10.1038/s41467-019-08582-7
PMCID:
PMC6372624
AbstractArticlePDF–1.4M
16.
Inhibition of autophagy via activation of PI3K/Akt/mTOR pathway contributes to the protection of hesperidin against myocardial ischemia/reperfusion injury
Xuefei Li, Xiaorong Hu, Jichun Wang, Weipan Xu, Chunfeng Yi, Ruisong Ma, Hong Jiang
Int J Mol Med. 2018 Oct; 42(4): 1917–1924. Published online 2018 Jul 30. doi: 10.3892/ijmm.2018.3794
PMCID:
PMC6108872
AbstractArticlePDF–955K
17.
Acupuncture modulates stress response by the mTOR signaling pathway in a rat post-traumatic stress disorder model
Ju-Young Oh, Yu-Kang Kim, Seung-Nam Kim, Bombi Lee, Jae-Hwan Jang, Sunoh Kwon, Hi-Joon Park
Sci Rep. 2018; 8: 11864. Published online 2018 Aug 8. doi: 10.1038/s41598-018-30337-5
PMCID:
PMC6082850
AbstractArticlePDF–3.0M
18.
Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats
Wen Han, Hao Wang, Longxiang Su, Yun Long, Na Cui, Dawei Liu
Mediators Inflamm. 2018; 2018: 4798209. Published online 2018 Jun 28. doi: 10.1155/2018/4798209
PMCID:
PMC6046132
AbstractArticlePDF–3.2M
19.
A Unique Homeostatic Signaling Pathway Links Synaptic Inactivity to Postsynaptic mTORC1
Fredrick E. Henry, Xiao Wang, David Serrano, Amanda S. Perez, Cynthia J. L. Carruthers, Edward L. Stuenkel, Michael A. Sutton
J Neurosci. 2018 Feb 28; 38(9): 2207–2225. doi: 10.1523/JNEUROSCI.1843-17.2017
PMCID:
PMC5830511
AbstractArticlePDF–4.1M
20.
Intrauterine growth retardation promotes fetal intestinal autophagy in rats via the mechanistic target of rapamycin pathway
Chao WANG, Ruiming ZHANG, Le ZHOU, Jintian HE, Qiang HUANG, Farman A SIYAL, Lili ZHANG, Xiang ZHONG, Tian WANG
J Reprod Dev. 2017 Dec; 63(6): 547–554. Published online 2017 Aug 31. doi: 10.1262/jrd.2017-050
PMCID:
PMC5735265
AbstractArticlePDF–861K

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