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Items: 1 to 20 of 66

1.
High Expression of a Cancer Stemness-Related Gene, Chromobox 8 (CBX8), in Normal Tissue Adjacent to the Tumor (NAT) Is Associated with Poor Prognosis of Colorectal Cancer Patients
Lui Ng, Hung-Sing Li, Abraham Tak-Ka Man, Ariel Ka-Man Chow, Dominic Chi-Chung Foo, Oswens Siu-Hung Lo, Roberta Wen-Chi Pang, Wai-Lun Law
Cells. 2022 Jun; 11(11): 1852. Published online 2022 Jun 6. doi: 10.3390/cells11111852
PMCID:
PMC9180723
AbstractArticlePDF–1.4M
2.
Optimization of Ligands using Focused DNA-encoded Libraries to Develop a Selective, Cell-permeable CBX8 Chromodomain Inhibitor
Sijie Wang, Kyle E. Denton, Kathryn F. Hobbs, Tyler Weaver, James M. B. McFarlane, Katelyn E. Connelly, Michael C. Gignac, Natalia Milosevich, Fraser Hof, Irina Paci, Catherine A. Musselman, Emily C. Dykhuizen, Casey J. Krusemark
ACS Chem Biol. Author manuscript; available in PMC 2021 Jan 17.
Published in final edited form as: ACS Chem Biol. 2020 Jan 17; 15(1): 112–131. Published online 2019 Dec 12. doi: 10.1021/acschembio.9b00654
PMCID:
PMC7247616
AbstractArticlePDF–2.1M
3.
Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association
Katelyn E Connelly, Tyler M Weaver, Aktan Alpsoy, Brian X Gu, Catherine A Musselman, Emily C Dykhuizen
Nucleic Acids Res. 2019 Mar 18; 47(5): 2289–2305. Published online 2018 Dec 29. doi: 10.1093/nar/gky1290
PMCID:
PMC6411926
AbstractArticlePDF–4.9M
4.
CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma
Bo Tang, Yu Tian, Yong Liao, Zeming Li, Shuiping Yu, Huizhao Su, Fudi Zhong, Guandou Yuan, Yan Wang, Hongping Yu, Stephen Tomlinson, Xiaoqiang Qiu, Songqing He
Cell Death Dis. 2019 Feb; 10(2): 52. Published online 2019 Jan 18. doi: 10.1038/s41419-018-1288-0
PMCID:
PMC6361915
AbstractArticlePDF–3.5M
5.
Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer
Jianjun Tang, Gang Wang, Meifang Zhang, Feng-yan Li, Yi Sang, Boqing Wang, Kaishun Hu, Yuanzhong Wu, Rongzhen Luo, Dan Liao, Jingying Cao, Xin Wang, Li Wang, Ruhua Zhang, Xiaoshi Zhang, Wu-Guo Deng, Dan Xie, Rui-hua Xu, Tiebang Kang
Oncotarget. 2014 Nov; 5(21): 10778–10790. Published online 2014 Oct 24. doi: 10.18632/oncotarget.2502
PMCID:
PMC4279409
AbstractArticlePDF–5.5M
6.
CBX8 interacts with chromatin PTEN and is involved in regulating mitotic progression
Byeong Hyeok Choi, Tania Marlyn Colon, Eunji Lee, Ziyue Kou, Wei Dai
Cell Prolif. 2021 Nov; 54(11): e13110. Published online 2021 Sep 30. doi: 10.1111/cpr.13110
PMCID:
PMC8560621
AbstractArticlePDF–1004K
7.
hsa-miR-429 targets CBX8 to promote cell apoptosis in diffuse large B-cell lymphoma
Yan Liang, Zhuo-Jun Yu, Min Liu, Hui-Min Liu, Jiang-Zhao Zhang, Tao Xiong, Yuan-Yan Tang, Zhi-Ping Huang
Mol Med Rep. 2021 Dec; 24(6): 857. Published online 2021 Oct 14. doi: 10.3892/mmr.2021.12497
PMCID:
PMC8548936
AbstractArticlePDF–5.1M
8.
KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway
Fanchang Zeng, Liumei Luo, Daoyuan Li, Juncheng Guo, Min Guo
J Transl Med. 2021; 19: 112. Published online 2021 Mar 17. doi: 10.1186/s12967-021-02709-5
PMCID:
PMC7972191
AbstractArticlePDF–1.4M
9.
Chromobox homolog 8 is a predictor of muscle invasive bladder cancer and promotes cell proliferation by repressing the p53 pathway
Gang‐jun Yuan, Xin Chen, Jun Lu, Zi‐hao Feng, Si‐liang Chen, Ri‐xin Chen, Wen‐su Wei, Fang‐jian Zhou, Dan Xie
Cancer Sci. 2017 Nov; 108(11): 2166–2175. Published online 2017 Sep 25. doi: 10.1111/cas.13383
Correction in:
Cancer Sci. 2023 Apr; 114(4): 1771.
PMCID:
PMC5665758
AbstractArticlePDF–1.9M
10.
CBX8 Suppresses Tumor Metastasis via Repressing Snail in Esophageal Squamous Cell Carcinoma
Gang Wang, Jianjun Tang, Weixiang Zhan, Ruhua Zhang, Meifang Zhang, Dan Liao, Xin Wang, Yuanzhong Wu, Tiebang Kang
Theranostics. 2017; 7(14): 3478–3488. Published online 2017 Aug 15. doi: 10.7150/thno.20717
PMCID:
PMC5596437
AbstractArticlePDF–2.4M
11.
A Novel Role of Chromodomain Protein CBX8 in DNA Damage Response
Jay Oza, Bratati Ganguly, Atul Kulkarni, Vasudeva Ginjala, Ming Yao, Shridar Ganesan
J Biol Chem. 2016 Oct 28; 291(44): 22881–22893. Published online 2016 Aug 23. doi: 10.1074/jbc.M116.725879
Correction in:
J Biol Chem. 2017 Jan 13; 292(2): 761.
PMCID:
PMC5087711
AbstractArticlePDF–3.2M
12.
CBX8, a novel DNA repair protein, promotes tumorigenesis in human esophageal carcinoma
Weifan Xiao, Chao Ou, Jinlong Qin, Feng Xing, Yi Sun, Zhi Li, Jin Qiu
Int J Clin Exp Pathol. 2014; 7(8): 4817–4826. Published online 2014 Jul 15.
PMCID:
PMC4152042
AbstractArticlePDF–1.4M
13.
Chromobox homolog 8 (CBX8) Interacts with Y-Box binding protein 1 (YBX1) to promote cellular proliferation in hepatocellular carcinoma cells
Lushan Xiao, Zixiao Zhou, Wenwen Li, Jie Peng, Qingcan Sun, Hongbo Zhu, Yang Song, Jin-Lin Hou, Jingyuan Sun, Hui-Chuan Cao, Dong Zhongyi, Dehua Wu, Li Liu
Aging (Albany NY) 2019 Sep 15; 11(17): 7123–7149. Published online 2019 Sep 8. doi: 10.18632/aging.102241
PMCID:
PMC6756871
AbstractArticlePDF–14M
14.
CBX8, a component of the repressive Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3
Bhavna Malik, Charles S. Hemenway
FEBS Lett. Author manuscript; available in PMC 2014 Sep 17.
Published in final edited form as: FEBS Lett. 2013 Sep 17; 587(18): 3038–3044. Published online 2013 Jul 25. doi: 10.1016/j.febslet.2013.07.034
PMCID:
PMC3800029
AbstractArticlePDF–1.7M
15.
MLL fusion partner AF9 is an intrinsically disordered transcriptional regulator which recruits multiple partners via coupled folding and binding
Benjamin I Leach, Aravinda Kuntimaddi, Charles R Schmidt, Tomasz Cierpicki, Stephanie A Johnson, John H. Bushweller
Structure. Author manuscript; available in PMC 2014 Jan 8.
Published in final edited form as: Structure. 2013 Jan 8; 21(1): 176–183. Published online 2012 Dec 20. doi: 10.1016/j.str.2012.11.011
PMCID:
PMC3545106
AbstractArticlePDF–1.0M
16.
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus
Nikolaj Dietrich, Adrian P Bracken, Emmanuelle Trinh, Charlotte K Schjerling, Haruhiko Koseki, Juri Rappsilber, Kristian Helin, Klaus H Hansen
EMBO J. 2007 Mar 21; 26(6): 1637–1648. Published online 2007 Mar 1. doi: 10.1038/sj.emboj.7601632
PMCID:
PMC1829390
AbstractArticlePDF–584K
17.
Recognition and Specificity Determinants of the Human Cbx Chromodomains
Lilia Kaustov, Hui Ouyang, Maria Amaya, Alexander Lemak, Nataliya Nady, Shili Duan, Gregory A. Wasney, Zhihong Li, Masoud Vedadi, Matthieu Schapira, Jinrong Min, Cheryl H. Arrowsmith
J Biol Chem. 2011 Jan 7; 286(1): 521–529. Published online 2010 Nov 3. doi: 10.1074/jbc.M110.191411
PMCID:
PMC3013012
AbstractArticlePDF–2.0M
18.
CBX8, a Polycomb Group Protein, is Essential for MLL-AF9-Induced Leukemogenesis
Jiaying Tan, Morgan Jones, Haruhiko Koseki, Manabu Nakayama, Andrew Muntean, Ivan Maillard, Jay L. Hess
Cancer Cell. Author manuscript; available in PMC 2012 Nov 15.
Published in final edited form as: Cancer Cell. 2011 Nov 15; 20(5): 563–575. doi: 10.1016/j.ccr.2011.09.008
PMCID:
PMC3220883
AbstractArticlePDF–3.9M
19.
Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences
Claudius Vincenz, Tom K. Kerppola
Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43): 16572–16577. Published online 2008 Oct 16. doi: 10.1073/pnas.0805317105
PMCID:
PMC2568982
AbstractArticlePDF–1.2M
20.
Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor
Selma El Messaoudi-Aubert, James Nicholls, Goedele N. Maertens, Sharon Brookes, Emily Bernstein, Gordon Peters
Nat Struct Mol Biol. Author manuscript; available in PMC 2011 Jan 1.
Published in final edited form as: Nat Struct Mol Biol. 2010 Jul; 17(7): 862–868. Published online 2010 Jun 13. doi: 10.1038/nsmb.1824
PMCID:
PMC2929459
AbstractArticlePDF–1.1M

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