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Items: 1 to 20 of 23

1.
Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma
Ryan J. Boyd, Tien L. Olson, James D. Zook, Derek Stein, Manuel Aceves, Wan‐Hsin Lin, Felicia M. Craciunescu, Debra T. Hansen, Panos Z. Anastasiadis, Abhishek Singharoy, Petra Fromme
FASEB J. 2022 Jul; 36(7): e22378. Published online 2022 May 31. doi: 10.1096/fj.202101808RR
PMCID:
PMC9262375
AbstractArticlePDF–1.9M
2.
Mutations in the PLEKHG5 gene is relevant with autosomal recessive intermediate Charcot-Marie-Tooth disease
Hyeon Jin Kim, Young Bin Hong, Jin-Mo Park, Yu-Ri Choi, Ye Jin Kim, Bo Ram Yoon, Heasoo Koo, Jeong Hyun Yoo, Sang Beom Kim, Minhwa Park, Ki Wha Chung, Byung-Ok Choi
Orphanet J Rare Dis. 2013; 8: 104. Published online 2013 Jul 12. doi: 10.1186/1750-1172-8-104
PMCID:
PMC3728151
AbstractArticlePDF–2.9M
3.
The Nuclear Factor κB–Activator Gene PLEKHG5 Is Mutated in a Form of Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset
Isabelle  Maystadt, René  Rezsöhazy, Martine  Barkats, Sandra  Duque, Pascal  Vannuffel, Sophie  Remacle, Barbara  Lambert, Mustapha  Najimi, Etienne  Sokal, Arnold  Munnich, Louis  Viollet, Christine  Verellen-Dumoulin
Am J Hum Genet. 2007 Jul; 81(1): 67–76. Published online 2007 May 16. doi: 10.1086/518900
PMCID:
PMC1950913
AbstractArticlePDF–598K
4.
PLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells
Kaya Elisa Witte, Carsten Slotta, Melanie Lütkemeyer, Angelika Kitke, Roland Coras, Matthias Simon, Christian Kaltschmidt, Barbara Kaltschmidt
Sci Rep. 2020; 10: 21858. Published online 2020 Dec 14. doi: 10.1038/s41598-020-77958-3
PMCID:
PMC7736842
AbstractArticlePDF–11M
5.
The RhoGEF protein Plekhg5 regulates apical constriction of bottle cells during gastrulation
Ivan K. Popov, Heather J. Ray, Paul Skoglund, Ray Keller, Chenbei Chang
Development. 2018 Dec 15; 145(24): dev168922. Published online 2018 Dec 12. doi: 10.1242/dev.168922
PMCID:
PMC6307888
AbstractArticle
6.
PLEKHG5 deficiency leads to an intermediate form of autosomal-recessive Charcot–Marie–Tooth disease
Hamid Azzedine, Petra Zavadakova, Violaine Planté-Bordeneuve, Maria Vaz Pato, Nuno Pinto, Luca Bartesaghi, Jennifer Zenker, Olivier Poirot, Nathalie Bernard-Marissal, Estelle Arnaud Gouttenoire, Romain Cartoni, Alexandra Title, Giulia Venturini, Jean-Jacques Médard, Edward Makowski, Ludger Schöls, Kristl G. Claeys, Claudia Stendel, Andreas Roos, Joachim Weis, Odile Dubourg, José Leal Loureiro, Giovanni Stevanin, Gérard Said, Anthony Amato, Jay Baraban, Eric LeGuern, Jan Senderek, Carlo Rivolta, Roman Chrast
Hum Mol Genet. 2013 Oct 15; 22(20): 4224–4232. Published online 2013 Jun 17. doi: 10.1093/hmg/ddt274
PMCID:
PMC3983407
AbstractArticlePDF–1.2M
7.
The Rho Guanine Nucleotide Exchange Factor Syx Regulates the Balance of Dia and ROCK Activities To Promote Polarized-Cancer-Cell Migration
Justus C. Dachsel, Siu P. Ngok, Laura J. Lewis-Tuffin, Antonis Kourtidis, Rory Geyer, Lauren Johnston, Ryan Feathers, Panos Z. Anastasiadis
Mol Cell Biol. 2013 Dec; 33(24): 4909–4918. doi: 10.1128/MCB.00565-13
PMCID:
PMC3889543
AbstractArticlePDF–3.8M
8.
Phosphorylation-mediated 14-3-3 Protein Binding Regulates the Function of the Rho-specific Guanine Nucleotide Exchange Factor (RhoGEF) Syx
Siu P. Ngok, Rory Geyer, Antonis Kourtidis, Peter Storz, Panos Z. Anastasiadis
J Biol Chem. 2013 Mar 1; 288(9): 6640–6650. Published online 2013 Jan 18. doi: 10.1074/jbc.M112.432682
PMCID:
PMC3585103
AbstractArticlePDF–3.6M
9.
The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors
Liuh Ling Goh, Ed Manser
J Biol Chem. 2012 Sep 7; 287(37): 31311–31320. Published online 2012 Jul 17. doi: 10.1074/jbc.M111.327056
PMCID:
PMC3442376
AbstractArticlePDF–2.2M
10.
The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain
Liuh Ling Goh, Ed Manser
PLoS One. 2010; 5(8): e12409. Published online 2010 Aug 25. doi: 10.1371/journal.pone.0012409
PMCID:
PMC2928299
AbstractArticlePDF–1.6M
11.
Common variants at ten loci influence myocardial repolarization: the QTGEN consortium
Christopher Newton-Cheh, Mark Eijgelsheim, Kenneth Rice, Paul I. W. de Bakker, Xiaoyan Yin, Karol Estrada, Joshua Bis, Kristin Marciante, Fernando Rivadeneira, Peter A. Noseworthy, Nona Sotoodehnia, Nicholas L. Smith, Jerome I. Rotter, Jan A. Kors, Jacqueline C.M. Witteman, Albert Hofman, Susan R. Heckbert, Christopher J. O’Donnell, Andre G. Uitterlinden, Bruce M. Psaty, Thomas Lumley, Martin G. Larson, Bruno H.Ch. Stricker
Nat Genet. Author manuscript; available in PMC 2009 Oct 1.
Published in final edited form as: Nat Genet. 2009 Apr; 41(4): 399–406. Published online 2009 Mar 22. doi: 10.1038/ng.364
PMCID:
PMC2701449
AbstractArticlePDF–804K
12.
Biochemical and Computational Analysis Of LNX1 Interacting Proteins
Cheryl D. Wolting, Emily K. Griffiths, Renu Sarao, Brittany C. Prevost, Leanne E. Wybenga-Groot, C. Jane McGlade
PLoS One. 2011; 6(11): e26248. Published online 2011 Nov 8. doi: 10.1371/journal.pone.0026248
PMCID:
PMC3210812
AbstractArticlePDF–1.5M
13.
Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis
Anthony W. Harrington, Ju Young Kim, Sung Ok Yoon
J Neurosci. 2002 Jan 1; 22(1): 156–166. doi: 10.1523/JNEUROSCI.22-01-00156.2002
PMCID:
PMC6757583
AbstractArticlePDF–582K
14.
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity
HD Hosgood, III, L Zhang, M Shen, SI Berndt, R Vermeulen, G Li, S Yin, M Yeager, J Yuenger, N Rothman, S Chanock, M Smith, Q Lan
Occup Environ Med. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Occup Environ Med. 2009 Dec; 66(12): 848–853. Published online 2009 Sep 22. doi: 10.1136/oem.2008.044024
PMCID:
PMC2928224
AbstractArticlePDF–321K
15.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057
PMCID:
PMC6831851
AbstractArticlePDF–9.8M
16.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
17.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
18.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
19.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M

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