PMC Links for Gene (Select 578) - PMC

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Select item 93461281.

A common deletion at BAK1 reduces enhancer activity and confers risk of intracranial germ cell tumors

Kyuto Sonehara, Yui Kimura, Yoshiko Nakano, Tatsuya Ozawa, Meiko Takahashi, Ken Suzuki, Takashi Fujii, Yuko Matsushita, Arata Tomiyama, Toshihiro Kishikawa, Kenichi Yamamoto, Tatsuhiko Naito, Tomonari Suzuki, Shigeru Yamaguchi, Tomoru Miwa, Hikaru Sasaki, Masashi Kitagawa, Naoyuki Ohe, Junya Fukai, Hideki Ogiwara, Atsufumi Kawamura, Satoru Miyawaki, Fumihiko Matsuda, Nobutaka Kiyokawa, Koichi Ichimura, Ryo Nishikawa, Yukinori Okada, Keita Terashima

Nat Commun. 2022; 13: 4478. Published online 2022 Aug 2. doi: 10.1038/s41467-022-32005-9

PMCID:: PMC9346128

Abstract Article PDF–2.7M

Select item 87528372.

Structural basis of BAK activation in mitochondrial apoptosis initiation

Geetika Singh, Cristina D. Guibao, Jayaraman Seetharaman, Anup Aggarwal, Christy R. Grace, Dan E. McNamara, Sivaraja Vaithiyalingam, M. Brett Waddell, Tudor Moldoveanu

Nat Commun. 2022; 13: 250. Published online 2022 Jan 11. doi: 10.1038/s41467-021-27851-y

PMCID:: PMC8752837

Abstract Article PDF–6.5M

Select item 69894093.

Association Between BAK1 Gene rs210138 Polymorphisms and Testicular Germ Cell Tumors: A Systematic Review and Meta-Analysis

Jiaxuan Qin, Yufeng Yang, Xuan Zhuang, Jinchun Xing

Front Endocrinol (Lausanne) 2020; 11: 2. Published online 2020 Jan 23. doi: 10.3389/fendo.2020.00002

PMCID:: PMC6989409

Abstract Article PDF–670K

Select item 53028844.

Disordered clusters of Bak dimers rupture mitochondria during apoptosis

Rachel T Uren, Martin O’Hely, Sweta Iyer, Ray Bartolo, Melissa X Shi, Jason M Brouwer, Amber E Alsop, Grant Dewson, Ruth M Kluck

eLife. 2017; 6: e19944. Published online 2017 Feb 6. doi: 10.7554/eLife.19944

PMCID:: PMC5302884

Abstract Article PDF–7.2M

Select item 49407005.

Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever

Tran Ngoc Dang, Izumi Naka, Areerat Sa-Ngasang, Surapee Anantapreecha, Nuanjun Wichukchinda, Pathom Sawanpanyalert, Jintana Patarapotikul, Naoyuki Tsuchiya, Jun Ohashi

BMC Med Genet. 2016; 17: 43. Published online 2016 Jul 11. doi: 10.1186/s12881-016-0305-3

PMCID:: PMC4940700

Abstract Article PDF–415K

Select item 48046066.

E6 proteins from low-risk human papillomavirus types 6 and 11 are able to protect keratinocytes from apoptosis via Bak degradation

Michael P. Underbrink, Crystal Dupuis, Jia Wang, Stephen K. Tyring

J Gen Virol. 2016 Mar 1; 97(Pt 3): 715–724. doi: 10.1099/jgv.0.000392

PMCID:: PMC4804606

Abstract Article PDF–2.9M

Select item 46179787.

Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells

Haiming Dai, Husheng Ding, X. Wei Meng, Kevin L. Peterson, Paula A. Schneider, Judith E. Karp, Scott H. Kaufmann

Genes Dev. 2015 Oct 15; 29(20): 2140–2152. doi: 10.1101/gad.267997.115

PMCID:: PMC4617978

Abstract Article PDF–1.7M

Select item 45834678.

High Bak Expression Is Associated with a Favorable Prognosis in Breast Cancer and Sensitizes Breast Cancer Cells to Paclitaxel

Yanwei Luo, Xinye Wang, Heran Wang, Yang Xu, Qiuyuan Wen, Songqing Fan, Ran Zhao, Shihe Jiang, Jing Yang, Yukun Liu, Xiayu Li, Wei Xiong, Jian Ma, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Joshua B. Phillips, Guiyuan Li, Ming Tan, Ming Zhou

PLoS One. 2015; 10(9): e0138955. Published online 2015 Sep 25. doi: 10.1371/journal.pone.0138955

PMCID:: PMC4583467

Abstract Article PDF–4.0M

Select item 45637819.

Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains

S Iyer, F Bell, D Westphal, K Anwari, J Gulbis, B J Smith, G Dewson, R M Kluck

Cell Death Differ. 2015 Oct; 22(10): 1665–1675. Published online 2015 Mar 6. doi: 10.1038/cdd.2015.15

PMCID:: PMC4563781

Abstract Article PDF–1.3M

Select item 379502310.

Type I Interferon Upregulates Bak and Contributes to T Cell Loss during Human Immunodeficiency Virus (HIV) Infection

Joseph A. Fraietta, Yvonne M. Mueller, Guibin Yang, Alina C. Boesteanu, Donald T. Gracias, Duc H. Do, Jennifer L. Hope, Noshin Kathuria, Shannon E. McGettigan, Mark G. Lewis, Luis D. Giavedoni, Jeffrey M. Jacobson, Peter D. Katsikis

PLoS Pathog. 2013 Oct; 9(10): e1003658. Published online 2013 Oct 10. doi: 10.1371/journal.ppat.1003658

PMCID:: PMC3795023

Abstract Article PDF–1.3M

Select item 377762011.

A novel biomarker harvesting nanotechnology identifies Bak as a candidate melanoma biomarker in serum

Caterina Longo, Guido Gambara, Virginia Espina, Alessandra Luchini, Barney Bishop, Alexis S. Patanarut, Emanuel F. Petricoin, III, Francesca Beretti, Barbara Ferrari, Enrico Garaci, Anto De Pol, Giovanni Pellacani, Lance A. Liotta

Exp Dermatol. Author manuscript; available in PMC 2013 Sep 19.

Published in final edited form as: Exp Dermatol. 2011 Jan; 20(1): 29–34. doi: 10.1111/j.1600-0625.2010.01187.x

PMCID:: PMC3777620

Abstract Article PDF–800K

Select item 356397912.

Bak apoptotic function is not directly regulated by phosphorylation

V H Tran, R Bartolo, D Westphal, A Alsop, G Dewson, R M Kluck

Cell Death Dis. 2013 Jan; 4(1): e452. Published online 2013 Jan 10. doi: 10.1038/cddis.2012.191

PMCID:: PMC3563979

Abstract Article PDF–1.1M

Select item 350666113.

Blockade of the BAK Hydrophobic Groove by Inhibitory Phosphorylation Regulates Commitment to Apoptosis

Abul Azad, Joanna Fox, Sabrina Leverrier, Alan Storey

PLoS One. 2012; 7(11): e49601. Published online 2012 Nov 26. doi: 10.1371/journal.pone.0049601

PMCID:: PMC3506661

Abstract Article PDF–2.6M

Select item 304980514.

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei-Xing Zong, Emily H. -Y. Cheng, Tullia Lindsten, Vily Panoutsakopoulou, Andrea J. Ross, Kevin A. Roth, Grant R. MacGregor, Craig B. Thompson, Stanley J. Korsmeyer

Science. Author manuscript; available in PMC 2011 Mar 7.

Published in final edited form as: Science. 2001 Apr 27; 292(5517): 727–730. doi: 10.1126/science.1059108

PMCID:: PMC3049805

Abstract Article PDF–2.5M

Select item 304870815.

Reconstitution of Proapoptotic BAK Function in Liposomes Reveals a Dual Role for Mitochondrial Lipids in the BAK-driven Membrane Permeabilization Process

Olatz Landeta, Ane Landajuela, David Gil, Stefka Taneva, Carmelo DiPrimo, Begoña Sot, Mikel Valle, Vadim A. Frolov, Gorka Basañez

J Biol Chem. 2011 Mar 11; 286(10): 8213–8230. Published online 2011 Jan 1. doi: 10.1074/jbc.M110.165852

PMCID:: PMC3048708

Abstract Article PDF–3.1M

Select item 298910216.

Tyrosine dephosphorylation is required for Bak activation in apoptosis

Joanna L Fox, Ferina Ismail, Abul Azad, Nicola Ternette, Sabrina Leverrier, Mariola J Edelmann, Benedikt M Kessler, Irene M Leigh, Sarah Jackson, Alan Storey

EMBO J. 2010 Nov 17; 29(22): 3853–3868. Published online 2010 Oct 19. doi: 10.1038/emboj.2010.244