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Select item 42866321.

The multispecific thyroid hormone transporter OATP1C1 mediates cell-specific sulforhodamine 101-labeling of hippocampal astrocytes

Christian Schnell, Ali Shahmoradi, Sven P. Wichert, Steffen Mayerl, Yohannes Hagos, Heike Heuer, Moritz J. Rossner, Swen Hülsmann

Brain Struct Funct. 2015; 220(1): 193–203. Published online 2013 Oct 16. doi: 10.1007/s00429-013-0645-0

PMCID:: PMC4286632

Abstract Article PDF–3.0M

Select item 106053082.

Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function

Devon Siemes, Pieter Vancamp, Boyka Markova, Philippa Spangenberg, Olga Shevchuk, Bente Siebels, Hartmut Schlüter, Steffen Mayerl, Heike Heuer, Daniel Robert Engel

Cells. 2023 Oct; 12(20): 2487. Published online 2023 Oct 19. doi: 10.3390/cells12202487

PMCID:: PMC10605308

Abstract Article PDF–3.5M

Select item 99668203.

Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice

Jiesi Chen, Eva Salveridou, Lutz Liebmann, Sivaraj M. Sundaram, Denica Doycheva, Boyka Markova, Christian A. Hübner, Anita Boelen, W. Edward Visser, Heike Heuer, Steffen Mayerl

Int J Mol Sci. 2023 Feb; 24(4): 3452. Published online 2023 Feb 9. doi: 10.3390/ijms24043452

PMCID:: PMC9966820

Abstract Article PDF–2.7M

Select item 97791614.

TRIAC Treatment Improves Impaired Brain Network Function and White Matter Loss in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice

Jonathan Rochus Reinwald, Wolfgang Weber-Fahr, Alejandro Cosa-Linan, Robert Becker, Markus Sack, Claudia Falfan-Melgoza, Natalia Gass, Urs Braun, Christian Clemm von Hohenberg, Jiesi Chen, Steffen Mayerl, Thomas F. Muente, Heike Heuer, Alexander Sartorius

Int J Mol Sci. 2022 Dec; 23(24): 15547. Published online 2022 Dec 8. doi: 10.3390/ijms232415547

PMCID:: PMC9779161

Abstract Article PDF–6.0M

Select item 96269365.

Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome

Gandhari Maity-Kumar, Lisa Ständer, Meri DeAngelis, Sooyeon Lee, Anna Molenaar, Lore Becker, Lillian Garrett, Oana V. Amerie, Sabine M. Hoelter, Wolfgang Wurst, Helmut Fuchs, Annette Feuchtinger, Valerie Gailus-Durner, Cristina Garcia-Caceres, Ahmed E. Othman, Caroline Brockmann, Vanessa I. Schöffling, Katja Beiser, Heiko Krude, Piotr A. Mroz, Susanna Hofmann, Jan Tuckermann, Richard D. DiMarchi, Martin Hrabe de Angelis, Matthias H. Tschöp, Paul T. Pfluger, Timo D. Müller

Mol Metab. 2022 Dec; 66: 101616. Published online 2022 Oct 18. doi: 10.1016/j.molmet.2022.101616

PMCID:: PMC9626936

Abstract Article PDF–2.8M

Select item 78786966.

Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone

Cristina Luongo, Lucile Butruille, Anthony Sébillot, Karine Le Blay, Markus Schwaninger, Heike Heuer, Barbara A. Demeneix, Sylvie Remaud

Stem Cell Reports. 2021 Feb 9; 16(2): 337–353. Published online 2021 Jan 14. doi: 10.1016/j.stemcr.2020.12.009

PMCID:: PMC7878696

Abstract Article PDF–2.5M

Select item 54147847.

In Vitro and Mouse Studies Supporting Therapeutic Utility of Triiodothyroacetic Acid in MCT8 Deficiency

Simone Kersseboom, Sigrun Horn, W. Edward Visser, Jiesi Chen, Edith C. H. Friesema, Catherine Vaurs-Barrière, Robin P. Peeters, Heike Heuer, Theo J. Visser

Mol Endocrinol. 2014 Dec; 28(12): 1961–1970. Published online 2014 Nov 12. doi: 10.1210/me.2014-1135

PMCID:: PMC5414784

Abstract Article

Select item 40015338.

Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis

Steffen Mayerl, Julia Müller, Reinhard Bauer, Sarah Richert, Celia M. Kassmann, Veerle M. Darras, Katrin Buder, Anita Boelen, Theo J. Visser, Heike Heuer

J Clin Invest. 2014 May 1; 124(5): 1987–1999. Published online 2014 Apr 1. doi: 10.1172/JCI70324

PMCID:: PMC4001533

Abstract Article PDF–5.6M

Select item 85983869.

The Thyroid Hormone Transporter MCT10 Is a Novel Regulator of Trabecular Bone Mass and Bone Turnover in Male Mice

Franziska Lademann, Steffen Mayerl, Elena Tsourdi, Francois Verrey, Victoria D Leitch, Graham R Williams, J H Duncan Bassett, Lorenz C Hofbauer, Heike Heuer, Martina Rauner

Endocrinology. 2022 Jan; 163(1): bqab218. Published online 2021 Oct 20. doi: 10.1210/endocr/bqab218

PMCID:: PMC8598386

Abstract Article

Select item 599353610.

Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration

Steffen Mayerl, Manuel Schmidt, Denica Doycheva, Veerle M. Darras, Sören S. Hüttner, Anita Boelen, Theo J. Visser, Christoph Kaether, Heike Heuer, Julia von Maltzahn

Stem Cell Reports. 2018 Jun 5; 10(6): 1959–1974. Published online 2018 Apr 26. doi: 10.1016/j.stemcr.2018.03.021

PMCID:: PMC5993536

Abstract Article PDF–4.5M

Select item 439931011.

Parallel Regulation of Thyroid Hormone Transporters OATP1c1 and MCT8 During and After Endotoxemia at the Blood-Brain Barrier of Male Rodents

Gábor Wittmann, Judit Szabon, Petra Mohácsik, Shira S. Nouriel, Balázs Gereben, Csaba Fekete, Ronald M. Lechan

Endocrinology. 2015 Apr; 156(4): 1552–1564. Published online 2015 Jan 16. doi: 10.1210/en.2014-1830

PMCID:: PMC4399310

Abstract Article

Select item 323004612.

Developmental and Cell-Specific Expression of Thyroid Hormone Transporters in the Mouse Cochlea

David S. Sharlin, Theo J. Visser, Douglas Forrest

Endocrinology. 2011 Dec; 152(12): 5053–5064. Published online 2011 Aug 30. doi: 10.1210/en.2011-1372

PMCID:: PMC3230046

Abstract Article

Select item 875437513.

Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development

Steffen Mayerl, Jiesi Chen, Eva Salveridou, Anita Boelen, Veerle M Darras, Heike Heuer

Cereb Cortex. 2022 Jan 15; 32(2): 329–341. Published online 2021 Jul 31. doi: 10.1093/cercor/bhab211

PMCID:: PMC8754375

Abstract Article PDF–2.3M

Select item 368927914.

Changes in Thyroid Status During Perinatal Development of MCT8-Deficient Male Mice

Alfonso Massimiliano Ferrara, Xiao-Hui Liao, Pilar Gil-Ibáñez, Teresa Marcinkowski, Juan Bernal, Roy E. Weiss, Alexandra M. Dumitrescu, Samuel Refetoff

Endocrinology. 2013 Jul; 154(7): 2533–2541. Published online 2013 May 21. doi: 10.1210/en.2012-2031

PMCID:: PMC3689279

Abstract Article

Select item 666652615.

Neuronal 3′,3,5-Triiodothyronine (T₃) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T₃ Transporter Mutated in Allan–Herndon–Dudley Syndrome

Eva K. Wirth, Stephan Roth, Cristiane Blechschmidt, Sabine M. Hölter, Lore Becker, Ildiko Racz, Andreas Zimmer, Thomas Klopstock, Valerie Gailus-Durner, Helmut Fuchs, Wolfgang Wurst, Thomas Naumann, Anja Bräuer, Martin Hrabé de Angelis, Josef Köhrle, Annette Grüters, Ulrich Schweizer

J Neurosci. 2009 Jul 29; 29(30): 9439–9449. doi: 10.1523/JNEUROSCI.6055-08.2009

PMCID:: PMC6666526

Abstract Article PDF–8.8M

Select item 1020895816.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 263408517.

The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease

TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij

Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118

PMCID:: PMC2634085

Abstract Article PDF–629K

Select item 141356818.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

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