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Select item 51011691.

Context-specific function of S6K2 in helper T cell differentiation

Christine Pai, Craig M. Walsh, David A. Fruman

J Immunol. Author manuscript; available in PMC 2017 Oct 15.

Published in final edited form as: J Immunol. 2016 Oct 15; 197(8): 3049–3058. Published online 2016 Sep 9. doi: 10.4049/jimmunol.1600167

PMCID:: PMC5101169

Abstract Article PDF–1.8M

Select item 23970232.

IDENTIFICATION OF S6K2 AS A CENTROSOME-LOCATED KINASE

Rossella Rossi, John M. Pester, Mitch McDowell, Samuela Soza, Alessandra Montecucco, Kay K. Lee-Fruman

FEBS Lett. Author manuscript; available in PMC 2008 Aug 21.

Published in final edited form as: FEBS Lett. 2007 Aug 21; 581(21): 4058–4064. Published online 2007 Jul 30. doi: 10.1016/j.febslet.2007.07.047

PMCID:: PMC2397023

Abstract Article PDF–1.2M

Select item 52489543.

Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis

Satish K. Madala, Vishwaraj Sontake, Ramakrishna Edukulla, Cynthia R. Davidson, Stephanie Schmidt, William D. Hardie

Am J Respir Cell Mol Biol. 2016 Dec; 55(6): 792–803. doi: 10.1165/rcmb.2016-0090OC

PMCID:: PMC5248954

Abstract Article PDF–1.9M

Select item 37324854.

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

Weiping Cao, Santhakumar Manicassamy, Hua Tang, Sudhir Pai Kasturi, Ali Pirani, Niren Murthy, Bali Pulendran

Nat Immunol. Author manuscript; available in PMC 2013 Aug 3.

Published in final edited form as: Nat Immunol. 2008 Oct; 9(10): 1157–1164. Published online 2008 Aug 31. doi: 10.1038/ni.1645

PMCID:: PMC3732485

Abstract Article PDF–2.6M

Select item 35729935.

Dysregulation of Multiple Facets of Glycogen Metabolism in a Murine Model of Pompe Disease

Kristin M. Taylor, Elizabeth Meyers, Michael Phipps, Priya S. Kishnani, Seng H. Cheng, Ronald K. Scheule, Rodney J. Moreland

PLoS One. 2013; 8(2): e56181. Published online 2013 Feb 14. doi: 10.1371/journal.pone.0056181

PMCID:: PMC3572993

Abstract Article PDF–1.0M

Select item 32967186.

Metabolic Control by S6 Kinases Depends on Dietary Lipids

Tamara R. Castañeda, William Abplanalp, Sung Hee Um, Paul T. Pfluger, Brigitte Schrott, Kimberly Brown, Erin Grant, Larissa Carnevalli, Stephen C. Benoit, Donald A. Morgan, Dean Gilham, David Y. Hui, Kamal Rahmouni, George Thomas, Sara C. Kozma, Deborah J. Clegg, Matthias H. Tschöp

PLoS One. 2012; 7(3): e32631. Published online 2012 Mar 7. doi: 10.1371/journal.pone.0032631

PMCID:: PMC3296718

Abstract Article PDF–802K

Select item 28244027.

Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

Tommy Alain, XueQing Lun, Yvan Martineau, Polen Sean, Bali Pulendran, Emmanuel Petroulakis, Franz J. Zemp, Chantal G. Lemay, Dominic Roy, John C. Bell, George Thomas, Sara C. Kozma, Peter A. Forsyth, Mauro Costa-Mattioli, Nahum Sonenberg

Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4): 1576–1581. Published online 2010 Jan 4. doi: 10.1073/pnas.0912344107

PMCID:: PMC2824402

Abstract Article PDF–1.0M

Select item 25646098.

Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation

Samira Alliouachene, Robyn L. Tuttle, Stephanie Boumard, Thomas Lapointe, Sophie Berissi, Stephane Germain, Francis Jaubert, David Tosh, Morris J. Birnbaum, Mario Pende

J Clin Invest. 2008 Nov 3; 118(11): 3629–3638. Published online 2008 Oct 9. doi: 10.1172/JCI35237

PMCID:: PMC2564609

Abstract Article PDF–2.1M

Select item 24242569.

S6 kinase 2 potentiates interleukin-3-driven cell proliferation

Rebecca Cruz, Lee Hedden, Derek Boyer, Michael G. Kharas, David A. Fruman, Kay K. Lee-Fruman

J Leukoc Biol. Author manuscript; available in PMC 2008 Jun 11.

Published in final edited form as: J Leukoc Biol. 2005 Dec; 78(6): 1378–1385. Published online 2005 Oct 4. doi: 10.1189/jlb.0405225

PMCID:: PMC2424256

Abstract Article PDF–1.3M

Select item 217051310.

Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity

Marcia D. Antion, Maayan Merhav, Charles A. Hoeffer, Gerald Reis, Sara C. Kozma, George Thomas, Erin M. Schuman, Kobi Rosenblum, Eric Klann

Learn Mem. 2008 Jan; 15(1): 29–38. doi: 10.1101/lm.661908

PMCID:: PMC2170513

Abstract Article PDF–755K

Select item 117101011.

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.

H Shima, M Pende, Y Chen, S Fumagalli, G Thomas, S C Kozma

EMBO J. 1998 Nov 16; 17(22): 6649–6659. doi: 10.1093/emboj/17.22.6649

PMCID:: PMC1171010

Summary PDF–511K

Select item 38160812.

S6K1^−/−/S6K2^−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

Mario Pende, Sung Hee Um, Virginie Mieulet, Melanie Sticker, Valerie L. Goss, Jurgen Mestan, Matthias Mueller, Stefano Fumagalli, Sara C. Kozma, George Thomas

Mol Cell Biol. 2004 Apr; 24(8): 3112–3124. doi: 10.1128/MCB.24.8.3112-3124.2004

PMCID:: PMC381608

Abstract Article PDF–705K

Select item 291639613.

mTORC1 Directly Phosphorylates and Regulates Human MAF1

Annemieke A. Michels, Aaron M. Robitaille, Diane Buczynski-Ruchonnet, Wassim Hodroj, Jaime H. Reina, Michael N. Hall, Nouria Hernandez

Mol Cell Biol. 2010 Aug; 30(15): 3749–3757. Published online 2010 Jun 1. doi: 10.1128/MCB.00319-10

PMCID:: PMC2916396

Abstract Article PDF–838K

Select item 275593114.

mTOR/S6 Kinase Pathway Contributes to Astrocyte Survival during Ischemia

María Dolores Pastor, Isaac García-Yébenes, Noelia Fradejas, José Manuel Pérez-Ortiz, Silvia Mora-Lee, Pedro Tranque, María Ángeles Moro, Mario Pende, Soledad Calvo

J Biol Chem. 2009 Aug 14; 284(33): 22067–22078. Published online 2009 Jun 17. doi: 10.1074/jbc.M109.033100

PMCID:: PMC2755931

Abstract Article PDF–2.7M

Select item 229308015.

mGluR-Dependent Long-Term Depression Is Associated with Increased Phosphorylation of S6 and Synthesis of Elongation Factor 1A but Remains Expressed in S6K-Deficient Mice

Marcia D. Antion, Lingfei Hou, Helen Wong, Charles A. Hoeffer, Eric Klann

Mol Cell Biol. 2008 May; 28(9): 2996–3007. Published online 2008 Mar 3. doi: 10.1128/MCB.00201-08

PMCID:: PMC2293080

Abstract Article PDF–1019K

Select item 660529516.

PKA-Dependent Phosphorylation of Ribosomal Protein S6 Does Not Correlate with Translation Efficiency in Striatonigral and Striatopallidal Medium-Sized Spiny Neurons

Anne Biever, Emma Puighermanal, Akinori Nishi, Alexandre David, Claire Panciatici, Sophie Longueville, Dimitris Xirodimas, Giuseppe Gangarossa, Oded Meyuhas, Denis Hervé, Jean-Antoine Girault, Emmanuel Valjent

J Neurosci. 2015 Mar 11; 35(10): 4113–4130. doi: 10.1523/JNEUROSCI.3288-14.2015

PMCID:: PMC6605295

Abstract Article PDF–8.4M

Select item 535056117.

ZRF1 is a novel S6 kinase substrate that drives the senescence programme

Manuela Barilari, Gregory Bonfils, Caroline Treins, Vonda Koka, Delphine De Villeneuve, Sylvie Fabrega, Mario Pende

EMBO J. 2017 Mar 15; 36(6): 736–750. Published online 2017 Feb 27. doi: 10.15252/embj.201694966

PMCID:: PMC5350561

Abstract Article PDF–2.2M

Select item 322382218.

S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy

Catherine Espeillac, Claudia Mitchell, Séverine Celton-Morizur, Céline Chauvin, Vonda Koka, Cynthia Gillet, Jeffrey H. Albrecht, Chantal Desdouets, Mario Pende

J Clin Invest. 2011 Jul 1; 121(7): 2821–2832. Published online 2011 Jun 1. doi: 10.1172/JCI44203

PMCID:: PMC3223822

Abstract Article PDF–3.5M

Select item 268203419.

Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals

Barbara Kroczynska, Surinder Kaur, Efstratios Katsoulidis, Beata Majchrzak-Kita, Antonella Sassano, Sara C. Kozma, Eleanor N. Fish, Leonidas C. Platanias

Mol Cell Biol. 2009 May; 29(10): 2865–2875. Published online 2009 Mar 16. doi: 10.1128/MCB.01537-08

PMCID:: PMC2682034

Abstract Article PDF–862K

Select item 731480620.

mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division

Martina Bonucci, Nicolas Kuperwasser, Serena Barbe, Vonda Koka, Delphine de Villeneuve, Chi Zhang, Nishit Srivastava, Xiaoying Jia, Matthew P. Stokes, Frank Bienaimé, Virginie Verkarre, Jean Baptiste Lopez, Fanny Jaulin, Marco Pontoglio, Fabiola Terzi, Benedicte Delaval, Matthieu Piel, Mario Pende

Nat Commun. 2020; 11: 3200. Published online 2020 Jun 24. doi: 10.1038/s41467-020-16978-z