PMC Links for Gene (Select 59091) - PMC

Andrew P. Landstrom, Qixin Yang, Bo Sun, Robin M. Perelli, Minu-Tshyeto Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M. Alsina, Shuyi Cao, Julia O. Reynolds, Tarah A. Word, Niels M.R. van der Sangen, Quinn Wells, Prince J. Kannankeril, Andreas Ludwig, Jeffrey J. Kim, Xander H.T. Wehrens

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2023 Feb; 16(2): e010858. Published online 2023 Jan 27. doi: 10.1161/CIRCEP.122.010858

PMCID:: PMC9974897

Abstract Article PDF–1.3M

Select item 41430264.

Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress

Ang Guo, Xiaoying Zhang, Venkat Ramesh Iyer, Biyi Chen, Caimei Zhang, William J. Kutschke, Robert M. Weiss, Clara Franzini-Armstrong, Long-Sheng Song

Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33): 12240–12245. Published online 2014 Aug 4. doi: 10.1073/pnas.1412729111

PMCID:: PMC4143026

Abstract Article PDF–1.5M

Select item 38306885.

Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization

David L. Beavers, Wei Wang, Sameer Ather, Niels Voigt, Alejandro Garbino, Sayali S. Dixit, Andrew P. Landstrom, Na Li, Qiongling Wang, Iacopo Olivotto, Dobromir Dobrev, Michael J. Ackerman, Xander H.T. Wehrens

J Am Coll Cardiol. Author manuscript; available in PMC 2014 Nov 19.

Published in final edited form as: J Am Coll Cardiol. 2013 Nov 19; 62(21): 10.1016/j.jacc.2013.06.052. Published online 2013 Aug 21. doi: 10.1016/j.jacc.2013.06.052

PMCID:: PMC3830688

Abstract Article PDF–2.6M

Select item 29904056.

Glutamate at position 227 of junctophilin-2 is involved in binding to TRPC3

Jin Seok Woo, Ji-Hye Hwang, Jae-Kyun Ko, Do Han Kim, Jianjie Ma, Eun Hui Lee

Mol Cell Biochem. Author manuscript; available in PMC 2010 Nov 23.

Published in final edited form as: Mol Cell Biochem. 2009 Aug; 328(1-2): 25–32. Published online 2009 Mar 10. doi: 10.1007/s11010-009-0070-0

PMCID:: PMC2990405

Abstract Article PDF–1.1M

Select item 101134267.

Nuclear Localization of a Novel Calpain-2 Mediated Junctophilin-2 C-terminal Cleavage Peptide Promotes Cardiomyocyte Remodeling

Satadru K. Lahiri, Ann P. Quick, Benoit Samson-Couterie, Mohit Hulsurkar, Ies Elzenaar, Gunnar Weninger, Stephan E. Lehnart, Ralph J. van Oort, Xander H.T. Wehrens

Basic Res Cardiol. Author manuscript; available in PMC 2023 Apr 19.

Published in final edited form as: Basic Res Cardiol. 2020 Jun 26; 115(4): 49. Published online 2020 Jun 26. doi: 10.1007/s00395-020-0807-1

PMCID:: PMC10113426

Abstract Article PDF–1.8M

Select item 78204338.

SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice

Shuai Wang, You Zhou, Yuanyuan Luo, Rongsheng Kan, Jingwen Chen, Haochen Xuan, Chaofan Wang, Junhong Chen, Tongda Xu, Dongye Li

Sci Rep. 2021; 11: 2037. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81570-4

PMCID:: PMC7820433

Abstract Article PDF–4.6M

Select item 68151359.

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility

Harry A. T. Pritchard, Caoimhin S. Griffin, Evan Yamasaki, Pratish Thakore, Conor Lane, Adam S. Greenstein, Scott Earley

Proc Natl Acad Sci U S A. 2019 Oct 22; 116(43): 21874–21881. Published online 2019 Oct 7. doi: 10.1073/pnas.1911304116

PMCID:: PMC6815135

Abstract Article PDF–1.3M

Select item 633667710.

E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator

Ang Guo, Yihui Wang, Biyi Chen, Yunhao Wang, Jinxiang Yuan, Liyang Zhang, Duane Hall, Jennifer Wu, Yun Shi, Qi Zhu, Cheng Chen, William H. Thiel, Xin Zhan, Robert M. Weiss, Fenghuang Zhan, Catherine A. Musselman, Miles Pufall, Weizhong Zhu, Kin Fai Au, Jiang Hong, Mark E. Anderson, Chad E. Grueter, Long-Sheng Song

Science. Author manuscript; available in PMC 2019 Dec 21.

Published in final edited form as: Science. 2018 Dec 21; 362(6421): eaan3303. Published online 2018 Nov 8. doi: 10.1126/science.aan3303

PMCID:: PMC6336677

Abstract Article PDF–2.4M

Select item 431856411.

Mutations in JPH2-Encoded Junctophilin-2 Associated with Hypertrophic Cardiomyopathy in Humans

Andrew P. Landstrom, Noah Weisleder, Karin B. Batalden, J. Martijn Bos, David J. Tester, Steve R. Ommen, Xander H.T Wehrens, William C. Claycomb, Jae-Kyun Ko, Moonsun Hwang, Zui Pan, Jianjie Ma, Michael J. Ackerman

J Mol Cell Cardiol. Author manuscript; available in PMC 2015 Feb 5.

Published in final edited form as: J Mol Cell Cardiol. 2007 Jun; 42(6): 1026–1035. Published online 2007 Apr 18. doi: 10.1016/j.yjmcc.2007.04.006

PMCID:: PMC4318564

Article PDF–899K

Select item 400630512.

Microtubule-Mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte T-Tubule Remodeling and Ca²⁺ Handling Dysfunction in Heart Failure

Caimei Zhang, Biyi Chen, Ang Guo, Yanqi Zhu, Jordan D. Miller, Shan Gao, Can Yuan, William Kutschke, Kathy Zimmerman, Robert M. Weiss, Xander H.T. Wehrens, Jiang Hong, Frances L. Johnson, Luis F. Santana, Mark E. Anderson, Long-Sheng Song

Circulation. Author manuscript; available in PMC 2015 Apr 29.

Published in final edited form as: Circulation. 2014 Apr 29; 129(17): 1742–1750. Published online 2014 Feb 11. doi: 10.1161/CIRCULATIONAHA.113.008452

PMCID:: PMC4006305

Abstract Article PDF–3.3M

Select item 377896113.

Critical roles of junctophilin-2 in T-tubule and excitation–contraction coupling maturation during postnatal development

Biyi Chen, Ang Guo, Caimei Zhang, Rong Chen, Yanqi Zhu, Jiang Hong, William Kutschke, Kathy Zimmerman, Robert M. Weiss, Leonid Zingman, Mark E. Anderson, Xander H.T. Wehrens, Long-Sheng Song

Cardiovasc Res. 2013 Oct 1; 100(1): 54–62. Published online 2013 Jul 16. doi: 10.1093/cvr/cvt180

PMCID:: PMC3778961

Abstract Article PDF–1.5M

Select item 313633614.

A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice

Jae-Kyun Ko, Kyoung-Han Choi, Xiaoli Zhao, Shinji Komazaki, Zui Pan, Noah Weisleder, Jianjie Ma

FASEB J. 2011 Aug; 25(8): 2638–2649. doi: 10.1096/fj.11-181560

PMCID:: PMC3136336

Abstract Article

Select item 305938015.

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling

Andrew P. Landstrom, Cherisse A. Kellen, Sayali S. Dixit, Ralph J. van Oort, Alejandro Garbino, Noah Weisleder, Jianjie Ma, Xander H.T. Wehrens, Michael J. Ackerman

Circ Heart Fail. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: Circ Heart Fail. 2011 Mar 1; 4(2): 214–223. Published online 2011 Jan 7. doi: 10.1161/CIRCHEARTFAILURE.110.958694

PMCID:: PMC3059380

Abstract Article PDF–1.2M

Select item 292786216.

T-tubule remodeling during transition from hypertrophy to heart failure

Sheng Wei, Ang Guo, Biyi Chen, William J. Kutschke, Yu-Ping Xie, Kathy Zimmerman, Robert M. Weiss, Mark E. Anderson, Heping Cheng, Long-Sheng Song

Circ Res. Author manuscript; available in PMC 2011 Aug 20.

Published in final edited form as: Circ Res. 2010 Aug 20; 107(4): 520–531. Published online 2010 Jun 24. doi: 10.1161/CIRCRESAHA.109.212324

PMCID:: PMC2927862

Abstract Article PDF–2.4M

Select item 219618617.

Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1

Koichi Ito, Shinji Komazaki, Kazushige Sasamoto, Morikatsu Yoshida, Miyuki Nishi, Kenji Kitamura, Hiroshi Takeshima

J Cell Biol. 2001 Sep 3; 154(5): 1059–1068. doi: 10.1083/jcb.200105040

PMCID:: PMC2196186

Abstract Article PDF–471K

Select item 662909718.

Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis

Sören Brandenburg, Jan Pawlowitz, Benjamin Eikenbusch, Jonas Peper, Tobias Kohl, Gyuzel Y. Mitronova, Samuel Sossalla, Gerd Hasenfuss, Xander H.T. Wehrens, Peter Kohl, Eva A. Rog-Zielinska, Stephan E. Lehnart

JCI Insight. 2019 Jun 20; 4(12): e127116. Published online 2019 Jun 20. doi: 10.1172/jci.insight.127116

PMCID:: PMC6629097

Abstract Article PDF–17M

Select item 592488819.

Physical interaction of junctophilin and the Ca_V1.1 C terminus is crucial for skeletal muscle contraction

Tsutomu Nakada, Toshihide Kashihara, Masatoshi Komatsu, Katsuhiko Kojima, Toshikazu Takeshita, Mitsuhiko Yamada

Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): 4507–4512. Published online 2018 Apr 9. doi: 10.1073/pnas.1716649115

PMCID:: PMC5924888

Abstract Article PDF–2.1M

Select item 520101320.

Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes

Michelle L. Munro, Isuru D. Jayasinghe, Qiongling Wang, Ann Quick, Wei Wang, David Baddeley, Xander H. T. Wehrens, Christian Soeller

J Cell Sci. 2016 Dec 1; 129(23): 4388–4398. doi: 10.1242/jcs.196873

PMCID:: PMC5201013

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