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Select item 111166731.

The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice

Wenkai Xia, Nuru Eltrich, Volker Vielhauer

Front Immunol. 2024; 15: 1377913. Published online 2024 May 10. doi: 10.3389/fimmu.2024.1377913

PMCID:: PMC11116673

Abstract Article PDF–15M

Select item 97425182.

The atypical chemokine receptor-2 fine-tunes the immune response in herpes stromal keratitis

Tian Yu, Fabian Schuette, Maria Christofi, John V. Forrester, Gerard J. Graham, Lucia Kuffova

Front Immunol. 2022; 13: 1054260. Published online 2022 Nov 28. doi: 10.3389/fimmu.2022.1054260

PMCID:: PMC9742518

Abstract Article PDF–6.5M

Select item 86386733.

Analysis of lung stromal expression of the atypical chemokine receptor ACKR2 reveals unanticipated expression in murine blood endothelial cells

Christopher A.H. Hansell, Samantha Love, Marieke Pingen, Gillian J. Wilson, Megan MacLeod, Gerard J. Graham

Eur J Immunol. 2020 May; 50(5): 666–675. Published online 2020 Mar 17. doi: 10.1002/eji.201948374

PMCID:: PMC8638673

Abstract Article PDF–5.7M

Select item 61761054.

The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis

Christopher A. H. Hansell, Alasdair R. Fraser, Alan J. Hayes, Marieke Pingen, Claire L. Burt, Kit Ming Lee, Laura Medina-Ruiz, Demi Brownlie, Megan K. L. Macleod, Paul Burgoyne, Gillian J. Wilson, Robert J. B. Nibbs, Gerard J. Graham

J Immunol. 2018 Oct 15; 201(8): 2510–2519. Published online 2018 Aug 29. doi: 10.4049/jimmunol.1800131

PMCID:: PMC6176105

Abstract Article PDF–1.2M

Select item 58130425.

ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity

Matteo Massara, Ornella Bonavita, Benedetta Savino, Nicoletta Caronni, Valeria Mollica Poeta, Marina Sironi, Elisa Setten, Camilla Recordati, Laura Crisafulli, Francesca Ficara, Alberto Mantovani, Massimo Locati, Raffaella Bonecchi

Nat Commun. 2018; 9: 676. Published online 2018 Feb 14. doi: 10.1038/s41467-018-03080-8

PMCID:: PMC5813042

Abstract Article PDF–1.1M

Select item 51760046.

Spread of Psoriasiform Inflammation to Remote Tissues Is Restricted by the Atypical Chemokine Receptor ACKR2

Kave Shams, Gillian J. Wilson, Mark Singh, Ellen H. van den Bogaard, Michelle L. Le Brocq, Susan Holmes, Joost Schalkwijk, A. David Burden, Clive S. McKimmie, Gerard J. Graham

J Invest Dermatol. 2017 Jan; 137(1): 85–94. doi: 10.1016/j.jid.2016.07.039

PMCID:: PMC5176004

Abstract Article

Select item 48213897.

Cell-autonomous regulation of neutrophil migration by the D6 chemokine decoy receptor

Antal Rot, Clive McKimmie, Claire L. Burt, Kenneth J Pallas, Thomas Jamieson, Monika Pruenster, Richard Horuk, Robert J.B. Nibbs, Gerard J. Graham

J Immunol. Author manuscript; available in PMC 2016 Apr 5.

Published in final edited form as: J Immunol. 2013 Jun 15; 190(12): 6450–6456. Published online 2013 May 13. doi: 10.4049/jimmunol.1201429

PMCID:: PMC4821389

Abstract Article PDF–639K

Select item 46990148.

Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice

Shirong Zheng, Susan Coventry, Lu Cai, David W. Powell, Venkatakrishna R. Jala, Bodduluri Haribabu, Paul N. Epstein

J Diabetes Res. 2016; 2016: 5362506. Published online 2015 Dec 20. doi: 10.1155/2016/5362506

PMCID:: PMC4699014

Abstract Article PDF–3.3M

Select item 43405119.

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens

Chris AH Hansell, Lindsay M MacLellan, Rachel S Oldham, James Doonan, Katie J Chapple, Elinor JR Anderson, Christopher Linington, Iain B McInnes, Robert JB Nibbs, Carl S Goodyear

Immunol Cell Biol. 2015 Feb; 93(2): 167–176. Published online 2014 Oct 28. doi: 10.1038/icb.2014.90

PMCID:: PMC4340511

Abstract Article PDF–2.2M

Select item 386876010.

Microarray Analyses Demonstrate the Involvement of Type I Interferons in Psoriasiform Pathology Development in D6-deficient Mice

Helen M. Baldwin, Kenneth Pallas, Vicky King, Thomas Jamieson, Clive S. McKimmie, Robert J. B. Nibbs, José M. Carballido, Marcus Jaritz, Antal Rot, Gerard J. Graham

J Biol Chem. 2013 Dec 20; 288(51): 36473–36483. Published online 2013 Nov 5. doi: 10.1074/jbc.M113.491563

PMCID:: PMC3868760

Abstract Article PDF–2.0M

Select item 323467411.

D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion

Kit Ming Lee, Clive S. McKimmie, Derek S. Gilchrist, Kenneth J. Pallas, Robert J. Nibbs, Paul Garside, Victoria McDonald, Christopher Jenkins, Richard Ransohoff, LiPing Liu, Simon Milling, Vuk Cerovic, Gerard J. Graham

Blood. 2011 Dec 1; 118(23): 6220–6229. Prepublished online 2011 Oct 6. doi: 10.1182/blood-2011-03-344044

PMCID:: PMC3234674

Abstract Article

Select item 318839912.

Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice

Chris A. H. Hansell, Chris Schiering, Ross Kinstrie, Laura Ford, Yvonne Bordon, Iain B. McInnes, Carl S. Goodyear, Robert J. B. Nibbs

Blood. Author manuscript; available in PMC 2011 Oct 6.

Published in final edited form as: Blood. 2011 May 19; 117(20): 5413–5424. Published online 2011 Mar 30. doi: 10.1182/blood-2010-11-317115

PMCID:: PMC3188399

Abstract Article PDF–1.2M

Select item 278619813.

The atypical chemokine receptor D6 contributes to the development of experimental colitis

Yvonne Bordon, Chris A. H. Hansell, David P Sester, Mairi Clarke, Allan McI. Mowat, Robert J. B. Nibbs

J Immunol. Author manuscript; available in PMC 2009 Dec 2.

Published in final edited form as: J Immunol. 2009 Apr 15; 182(8): 5032–5040. doi: 10.4049/jimmunol.0802802

PMCID:: PMC2786198

Abstract Article PDF–1.2M

Select item 252620214.

Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection

Diana Di Liberto, Massimo Locati, Nadia Caccamo, Annunciata Vecchi, Serena Meraviglia, Alfredo Salerno, Guido Sireci, Manuela Nebuloni, Neus Caceres, Pere-Joan Cardona, Francesco Dieli, Alberto Mantovani

J Exp Med. 2008 Sep 1; 205(9): 2075–2084. doi: 10.1084/jem.20070608

PMCID:: PMC2526202

Abstract Article PDF–1.3M

Select item 252619715.

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity

Maud Déruaz, Achim Frauenschuh, Ana L. Alessandri, João M. Dias, Fernanda M. Coelho, Remo C. Russo, Beatriz R. Ferreira, Gerard J. Graham, Jeffrey P. Shaw, Timothy N.C. Wells, Mauro M. Teixeira, Christine A. Power, Amanda E.I. Proudfoot

J Exp Med. 2008 Sep 1; 205(9): 2019–2031. doi: 10.1084/jem.20072689

PMCID:: PMC2526197

Abstract Article PDF–4.4M

Select item 219424216.

Immune Evasion by Murine Melanoma Mediated through CC Chemokine Receptor-10

Takashi Murakami, Adela R. Cardones, Steven E. Finkelstein, Nicholas P. Restifo, Brenda A. Klaunberg, Frank O. Nestle, S. Sianna Castillo, Phillip A. Dennis, Sam T. Hwang

J Exp Med. 2003 Nov 3; 198(9): 1337–1347. doi: 10.1084/jem.20030593

PMCID:: PMC2194242

Abstract Article PDF–550K

Select item 189926517.

The Chemokine Receptor D6 Has Opposing Effects on Allergic Inflammation and Airway Reactivity

Gregory S. Whitehead, Tie Wang, Laura M. DeGraff, Jeffrey W. Card, Sergio A. Lira, Gerard J. Graham, Donald N. Cook

Am J Respir Crit Care Med. 2007 Feb 1; 175(3): 243–249. Published online 2006 Nov 9. doi: 10.1164/rccm.200606-839OC

PMCID:: PMC1899265

Abstract Article PDF–1.1M

Select item 189295018.

Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6

Yeny Martinez de la Torre, Chiara Buracchi, Elena M. Borroni, Jana Dupor, Raffaella Bonecchi, Manuela Nebuloni, Fabio Pasqualini, Andrea Doni, Eleonora Lauri, Chiara Agostinis, Roberta Bulla, Donald N. Cook, Bodduluri Haribabu, Pierluigi Meroni, Daniel Rukavina, Luca Vago, Francesco Tedesco, Annunciata Vecchi, Sergio A. Lira, Massimo Locati, Alberto Mantovani

Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7): 2319–2324. Published online 2007 Feb 5. doi: 10.1073/pnas.0607514104

PMCID:: PMC1892950

Abstract Article PDF–2.1M

Select item 386716319.

Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection

Amir R. Hajrasouliha, Zahra Sadrai, Hyung K. Lee, Sunil K. Chauhan, Reza Dana

Mol Vis. 2013; 19: 2517–2525. Published online 2013 Dec 16.

PMCID:: PMC3867163

Abstract Article PDF–2.0M

Select item 353259220.

Elevated Expression of the Chemokine-Scavenging Receptor D6 Is Associated with Impaired Lesion Development in Psoriasis

Mark D. Singh, Vicky King, Helen Baldwin, David Burden, Anne Thorrat, Susan Holmes, Iain B. McInnes, Ruairidh Nicoll, Kave Shams, Kenneth Pallas, Thomas Jamieson, Kit Ming Lee, Jose M. Carballido, Antal Rot, Gerard J. Graham

Am J Pathol. 2012 Oct; 181(4): 1158–1164. doi: 10.1016/j.ajpath.2012.06.042

PMCID:: PMC3532592

Abstract Article PDF–1.2M

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