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Select item 112579451.

Retinoic acid related orphan receptor α is a genetic modifier that rescues retinal degeneration in a mouse model of Stargardt disease and Dry AMD

M. Akula, S. M. McNamee, Z. Love, N. Nasraty, N. P. M. Chan, M. Whalen, M. O. Avola, A. M. Olivares, B. D. Leehy, A. S. Jelcick, P. Singh, A. K. Upadhyay, D. F. Chen, N. B. Haider

Gene Ther. 2024; 31(7-8): 413–421. Published online 2024 May 16. doi: 10.1038/s41434-024-00455-z

PMCID:: PMC11257945

Abstract Article PDF–2.2M

Select item 107666232.

The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation

Mingsen Li, Huizhen Guo, Bofeng Wang, Zhuo Han, Siqi Wu, Jiafeng Liu, Huaxing Huang, Jin Zhu, Fengjiao An, Zesong Lin, Kunlun Mo, Jieying Tan, Chunqiao Liu, Li Wang, Xin Deng, Guigang Li, Jianping Ji, Hong Ouyang

Nat Commun. 2024; 15: 256. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44471-w

PMCID:: PMC10766623

Abstract Article PDF–8.2M

Select item 99590493.

Novel Therapeutic Potential of Retinoid-Related Orphan Receptor α in Cardiovascular Diseases

Yun Chen, Shu-Ping Zhang, Wei-Wei Gong, Yang-Yang Zheng, Jie-Ru Shen, Xiao Liu, Yun-Hui Gu, Jia-Hai Shi, Guo-Liang Meng

Int J Mol Sci. 2023 Feb; 24(4): 3462. Published online 2023 Feb 9. doi: 10.3390/ijms24043462

PMCID:: PMC9959049

Abstract Article PDF–3.2M

Select item 78664304.

Gender-specific associations between polymorphisms of the circadian gene RORA and cutaneous melanoma susceptibility

Clara Benna, Senthilkumar Rajendran, Giovanna Spiro, Chiara Menin, Luigi Dall’Olmo, Carlo Riccardo Rossi, Simone Mocellin

J Transl Med. 2021; 19: 57. Published online 2021 Feb 6. doi: 10.1186/s12967-021-02725-5

PMCID:: PMC7866430

Abstract Article PDF–957K

Select item 77022325.

Sedigheh Farahani, Leila Solgi, Sahar Bayat, Atieh Abedin Do, Shohreh Zare‐Karizi, Behnam Safarpour Lima, Reza Mirfakhraie

CNS Neurosci Ther. 2020 Dec; 26(12): 1315–1321. Published online 2020 Sep 5. doi: 10.1111/cns.13453

PMCID:: PMC7702232

Abstract Article PDF–949K

Select item 67414846.

Highly Pathogenic Influenza Viruses Inhibit Inflammatory Response in Monocytes via Activation of Rar-Related Orphan Receptor RORα

Judith Friesenhagen, Dorothee Viemann, Yvonne Börgeling, Mirco Schmolke, Christoph Spiekermann, Susanne Kirschnek, Stephan Ludwig, Johannes Roth

J Innate Immun. 2013 Jul; 5(5): 505–518. Published online 2013 Feb 22. doi: 10.1159/000346706

PMCID:: PMC6741484

Abstract Article PDF–312K

Select item 62615957.

RORα controls inflammatory state of human macrophages

Neda Nejati Moharrami, Erlend Bjørkøy Tande, Liv Ryan, Terje Espevik, Victor Boyartchuk

PLoS One. 2018; 13(11): e0207374. Published online 2018 Nov 28. doi: 10.1371/journal.pone.0207374

PMCID:: PMC6261595

Abstract Article PDF–3.7M

Select item 61279928.

The role of RORα in salivary gland lesions in patients with primary Sjögren’s syndrome

Xiuhong Weng, Yi Liu, Shun Cui, Bo Cheng

Arthritis Res Ther. 2018; 20: 205. Published online 2018 Sep 6. doi: 10.1186/s13075-018-1698-5

PMCID:: PMC6127992

Abstract Article PDF–4.4M

Select item 50499989.

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control

Zewen Kelvin Tuong, Rebecca Fitzsimmons, Shu-Ching Mary Wang, Tae Gyu Oh, Patrick Lau, Frederik Steyn, Gethin Thomas, George E.O. Muscat

EBioMedicine. 2016 Sep; 11: 101–117. Published online 2016 Aug 20. doi: 10.1016/j.ebiom.2016.08.027

PMCID:: PMC5049998

Abstract Article PDF–3.3M

Select item 501036210.

Circadian Clock-Related Genetic Risk Scores and Risk of Placental Abruption

Chunfang Qiu, Bizu Gelaye, Marie Denis, Mahlet G. Tadesse, Miguel Angel Luque Fernandez, Daniel A. Enquobahrie, Cande V. Ananth, Sixto E. Sanchez, Michelle A. Williams

Placenta. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Placenta. 2015 Dec; 36(12): 1480–1486. Published online 2015 Oct 23. doi: 10.1016/j.placenta.2015.10.005

PMCID:: PMC5010362

Abstract Article PDF–612K

Select item 442917311.

RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response

J M Hennings, M Uhr, T Klengel, P Weber, B Pütz, C Touma, D Czamara, M Ising, F Holsboer, S Lucae

Transl Psychiatry. 2015 Mar; 5(3): e538. Published online 2015 Mar 31. doi: 10.1038/tp.2015.9

PMCID:: PMC4429173

Abstract Article PDF–492K

Select item 386876712.

Nuclear Receptor-mediated Cell-autonomous Oscillatory Expression of the Circadian Transcription Factor, Neuronal PAS Domain Protein 2 (NPAS2)

Ritsuko Matsumura, Chiaki Matsubara, Koichi Node, Toru Takumi, Makoto Akashi

J Biol Chem. 2013 Dec 20; 288(51): 36548–36553. Published online 2013 Nov 6. doi: 10.1074/jbc.M113.517235

PMCID:: PMC3868767

Abstract Article PDF–1.2M

Select item 354665913.

RORα, a Potential Tumor Suppressor and Therapeutic Target of Breast Cancer

Jun Du, Ren Xu

Int J Mol Sci. 2012; 13(12): 15755–15766. Published online 2012 Nov 26. doi: 10.3390/ijms131215755

PMCID:: PMC3546659

Abstract Article PDF–269K

Select item 349478814.

A genome-wide association study of posttraumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus

Mark W. Logue, Clinton Baldwin, Guia Guffanti, Efi Melista, Erika J. Wolf, Annemarie F. Reardon, Monica Uddin, Derek Wildman, Sandro Galea, Karestan C. Koenen, Mark W. Miller

Mol Psychiatry. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Mol Psychiatry. 2013 Aug; 18(8): 937–942. Published online 2012 Aug 7. doi: 10.1038/mp.2012.113

PMCID:: PMC3494788

Abstract Article PDF–303K

Select item 314422415.

Control of Gene Expression by the Retinoic Acid-Related Orphan Receptor Alpha in HepG2 Human Hepatoma Cells

Caroline Chauvet, Amandine Vanhoutteghem, Christian Duhem, Gaëlle Saint-Auret, Brigitte Bois-Joyeux, Philippe Djian, Bart Staels, Jean-Louis Danan

PLoS One. 2011; 6(7): e22545. Published online 2011 Jul 26. doi: 10.1371/journal.pone.0022545

PMCID:: PMC3144224

Abstract Article PDF–469K

Select item 304204116.

Identification of SR8278, a Synthetic Antagonist of the Nuclear Heme Receptor REV-ERB

Douglas Kojetin, Yongjun Wang, Theodore M. Kameneck, Thomas P. Burris

ACS Chem Biol. Author manuscript; available in PMC 2012 Feb 18.

Published in final edited form as: ACS Chem Biol. 2011 Feb 18; 6(2): 131–134. Published online 2010 Nov 10. doi: 10.1021/cb1002575

PMCID:: PMC3042041

Abstract Article PDF–408K

Select item 304020617.

Sex Hormones in Autism: Androgens and Estrogens Differentially and Reciprocally Regulate RORA, a Novel Candidate Gene for Autism

Tewarit Sarachana, Minyi Xu, Ray-Chang Wu, Valerie W. Hu

PLoS One. 2011; 6(2): e17116. Published online 2011 Feb 16. doi: 10.1371/journal.pone.0017116

PMCID:: PMC3040206

Abstract Article PDF–1.1M

Select item 301085218.

A prospective study of common variants in the RAR-related orphan receptor alpha (RORalpha) gene and risk of neovascular age-related macular degeneration

Debra A. Schaumberg, Daniel Chasman, Margaux A. Morrison, Scott M. Adams, Qun Guo, David J. Hunter, Susan E. Hankinson, Margaret M. DeAngelis

Arch Ophthalmol. Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Arch Ophthalmol. 2010 Nov; 128(11): 1462–1471. doi: 10.1001/archophthalmol.2010.261

PMCID:: PMC3010852

Abstract Article PDF–417K

Select item 290929419.

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain

AnhThu Nguyen, Tibor A. Rauch, Gerd P. Pfeifer, Valerie W. Hu

FASEB J. 2010 Aug; 24(8): 3036–3051. doi: 10.1096/fj.10-154484

PMCID:: PMC2909294

Abstract Article

Select item 288439220.

Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach

Alexandra C. Silveira, Margaux A. Morrison, Fei Ji, Haiyan Xu, James B. Reinecke, Scott M. Adams, Trevor M. Arneberg, Maria Janssian, Joo-Eun Lee, Yang Yuan, Debra A. Schaumberg, Maria G. Kotoula, Evangeline E. Tsironi, Aristoteles N. Tsiloulis, Dimitrios Z. Chatzoulis, Joan W. Miller, Ivana K. Kim, Gregory H. Hageman, Lindsay A. Farrer, Neena B. Haider, Margaret M. DeAngelis

Vision Res. Author manuscript; available in PMC 2011 Mar 31.

Published in final edited form as: Vision Res. 2010 Mar 31; 50(7): 698–715. Published online 2009 Sep 26. doi: 10.1016/j.visres.2009.09.016

PMCID:: PMC2884392

Abstract Article PDF–2.7M

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