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Select item 109366361.

AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer

Syn Kok Yeo, Michael Haas, Kanakaraju Manupati, Mingang Hao, Fuchun Yang, Song Chen, Jun-Lin Guan

Autophagy. 2024; 20(3): 525–540. Published online 2023 Sep 21. doi: 10.1080/15548627.2023.2259775

PMCID:: PMC10936636

Abstract Article PDF–8.4M

Select item 107023662.

NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis

Swagatika Paul, Shireen A. Sarraf, Ki Hong Nam, Leila Zavar, Nicole DeFoor, Sahitya Ranjan Biswas, Lauren E. Fritsch, Tomer M. Yaron, Jared L. Johnson, Emily M. Huntsman, Lewis C. Cantley, Alban Ordureau, Alicia M. Pickrell

J Cell Biol. 2024 Feb 5; 223(2): e202303082. Published online 2023 Dec 7. doi: 10.1083/jcb.202303082

PMCID:: PMC10702366

Abstract Article PDF–8.5M

Select item 58868443.

^AZI23'UTR is a new SLC6A3 downregulator associated with an epistatic protection against substance use disorders

Kefu Liu, Jinlong Yu, Juan Zhao, Yanhong Zhou, Nian Xiong, Jie Xu, Tao Wang, Richard L. Bell, Hong Qing, Zhicheng Lin

Mol Neurobiol. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Mol Neurobiol. 2018 Jul; 55(7): 5611–5622. Published online 2017 Oct 5. doi: 10.1007/s12035-017-0781-2

PMCID:: PMC5886844

Abstract Article PDF–1.1M

Select item 50272474.

Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins

Faxiang Li, Xingqiao Xie, Yingli Wang, Jianping Liu, Xiaofang Cheng, Yujiao Guo, Yukang Gong, Shichen Hu, Lifeng Pan

Nat Commun. 2016; 7: 12708. Published online 2016 Sep 13. doi: 10.1038/ncomms12708

PMCID:: PMC5027247

Abstract Article PDF–2.7M

Select item 32156795.

Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen

Marc Le Breton, Laurène Meyniel-Schicklin, Alexandre Deloire, Bruno Coutard, Bruno Canard, Xavier de Lamballerie, Patrice Andre, Chantal Rabourdin-Combe, Vincent Lotteau, Nathalie Davoust

BMC Microbiol. 2011; 11: 234. Published online 2011 Oct 20. doi: 10.1186/1471-2180-11-234

PMCID:: PMC3215679

Abstract Article PDF–1.3M

Select item 62948826.

Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1

Tao Fu, Jianping Liu, Yingli Wang, Xingqiao Xie, Shichen Hu, Lifeng Pan

Proc Natl Acad Sci U S A. 2018 Dec 11; 115(50): E11651–E11660. Published online 2018 Nov 20. doi: 10.1073/pnas.1811421115

PMCID:: PMC6294882

Abstract Article PDF–3.1M

Select item 37003967.

Identification of Proteins that Interact with TANK Binding Kinase 1 and Testing for Mutations Associated with Glaucoma

Seongjin Seo, Frances Solivan-Timpe, Ben R. Roos, Alan L. Robin, Edwin M. Stone, Young H. Kwon, Wallace L.M. Alward, John H. Fingert

Curr Eye Res. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Curr Eye Res. 2013 Feb; 38(2): 310–315. Published online 2013 Jan 3. doi: 10.3109/02713683.2012.754047

PMCID:: PMC3700396

Abstract Article PDF–453K

Select item 64771528.

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

Benjamin J. Ravenhill, Keith B. Boyle, Natalia von Muhlinen, Cara J. Ellison, Glenn R. Masson, Elsje G. Otten, Agnes Foeglein, Roger Williams, Felix Randow

Mol Cell. 2019 Apr 18; 74(2): 320–329.e6. doi: 10.1016/j.molcel.2019.01.041

PMCID:: PMC6477152

Abstract Article

Select item 2075639.

Identification of NAP1, a Regulatory Subunit of IκB Kinase-Related Kinases That Potentiates NF-κB Signaling

Fumitaka Fujita, Yuko Taniguchi, Takashi Kato, Yasuko Narita, Akiko Furuya, Tatsuhiro Ogawa, Hiroaki Sakurai, Takashi Joh, Makoto Itoh, Mireille Delhase, Michael Karin, Makoto Nakanishi

Mol Cell Biol. 2003 Nov; 23(21): 7780–7793. doi: 10.1128/MCB.23.21.7780-7793.2003

PMCID:: PMC207563

Abstract Article PDF–774K

Select item 316954810.

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

Leonie Unterholzner, Rebecca P. Sumner, Marcin Baran, Hongwei Ren, Daniel S. Mansur, Nollaig M. Bourke, Felix Randow, Geoffrey L. Smith, Andrew G. Bowie

PLoS Pathog. 2011 Sep; 7(9): e1002247. Published online 2011 Sep 8. doi: 10.1371/journal.ppat.1002247

PMCID:: PMC3169548

Abstract Article PDF–2.5M

Select item 191409111.

SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK

Grigory Ryzhakov, Felix Randow

EMBO J. 2007 Jul 11; 26(13): 3180–3190. Published online 2007 Jun 14. doi: 10.1038/sj.emboj.7601743

PMCID:: PMC1914091

Abstract Article PDF–597K

Select item 569108312.

Autophagy acts through TRAF3 and RELB to regulate gene expression via antagonism of SMAD proteins

Alice C. Newman, Alain J. Kemp, Yvette Drabsch, Christian Behrends, Simon Wilkinson

Nat Commun. 2017; 8: 1537. Published online 2017 Nov 16. doi: 10.1038/s41467-017-00859-z

PMCID:: PMC5691083

Abstract Article PDF–2.3M

Select item 626810013.

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

Elodie Lafont, Peter Draber, Eva Rieser, Matthias Reichert, Sebastian Kupka, Diego de Miguel, Helena Draberova, Anne von Mässenhausen, Amandeep Bhamra, Stephen Henderson, Katarzyna Wojdyla, Avigayil Chalk, Silvia Surinova, Andreas Linkermann, Henning Walczak

Nat Cell Biol. Author manuscript; available in PMC 2019 May 12.

Published in final edited form as: Nat Cell Biol. 2018 Dec; 20(12): 1389–1399. Published online 2018 Nov 12. doi: 10.1038/s41556-018-0229-6

PMCID:: PMC6268100

Abstract Article PDF–2.8M

Select item 997119514.

CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway

Guojie Xu, Lei Zhao, Qingling Hua, Lanqing Wang, Hongli Liu, Zhenyu Lin, Min Jin, Jing Wang, Pengfei Zhou, Kunyu Yang, Gang Wu, Dandan Yu, Dejun Zhang, Tao Zhang

Cell Death Dis. 2023 Feb; 14(2): 167. Published online 2023 Feb 27. doi: 10.1038/s41419-023-05644-z

PMCID:: PMC9971195

Abstract Article PDF–15M

Select item 491053315.

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

Chantal Sellier, Maria‐Letizia Campanari, Camille Julie Corbier, Angeline Gaucherot, Isabelle Kolb‐Cheynel, Mustapha Oulad‐Abdelghani, Frank Ruffenach, Adeline Page, Sorana Ciura, Edor Kabashi, Nicolas Charlet‐Berguerand

EMBO J. 2016 Jun 15; 35(12): 1276–1297. Published online 2016 Apr 21. doi: 10.15252/embj.201593350

PMCID:: PMC4910533

Abstract Article PDF–1.5M

Select item 1033388416.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 325365817.

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf

Immunity. Author manuscript; available in PMC 2012 Sep 23.

Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014

Correction in:: volume 35 on page 647

PMCID:: PMC3253658

Abstract Article PDF–4.2M

Select item 629825418.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 773761019.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 553358520.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257