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Select item 84380421.

FBW7 couples structural integrity with functional output of primary cilia

Eleni Petsouki, Vasileios Gerakopoulos, Nicholas Szeto, Wenhan Chang, Mary Beth Humphrey, Leonidas Tsiokas

Commun Biol. 2021; 4: 1066. Published online 2021 Sep 13. doi: 10.1038/s42003-021-02504-4

PMCID:: PMC8438042

Abstract Article PDF–3.0M

Select item 31467282.

Human Mutations in NDE1 Cause Extreme Microcephaly with Lissencephaly

Fowzan S. Alkuraya, Xuyu Cai, Carina Emery, Ganeshwaran H. Mochida, Mohammed S. Al-Dosari, Jillian M. Felie, R. Sean Hill, Brenda J. Barry, Jennifer N. Partlow, Generoso G. Gascon, Amal Kentab, Mohammad Jan, Ranad Shaheen, Yuanyi Feng, Christopher A. Walsh

Am J Hum Genet. 2011 May 13; 88(5): 536–547. doi: 10.1016/j.ajhg.2011.04.003

Correction in:: Am J Hum Genet. 2011 May 13; 88(5): 677.

PMCID:: PMC3146728

Abstract Article PDF–1.2M

Select item 87508593.

The Cytoplasmic Dynein Associated Protein NDE1 Regulates Osteoclastogenesis by Modulating M-CSF and RANKL Signaling Pathways

Bhaba K. Das, Jyoti Gogoi, Aarthi Kannan, Ling Gao, Weirong Xing, Subburaman Mohan, Haibo Zhao

Cells. 2022 Jan; 11(1): 13. Published online 2021 Dec 22. doi: 10.3390/cells11010013

PMCID:: PMC8750859

Abstract Article PDF–6.5M

Select item 38693644.

LIS1 controls mitosis and mitotic spindle organization via the LIS1–NDEL1–dynein complex

Hyang Mi Moon, Yong Ha Youn, Hayley Pemble, Jessica Yingling, Torsten Wittmann, Anthony Wynshaw-Boris

Hum Mol Genet. 2014 Jan 15; 23(2): 449–466. Published online 2013 Sep 12. doi: 10.1093/hmg/ddt436

PMCID:: PMC3869364

Abstract Article PDF–2.2M

Select item 11508335.

Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway

Victor Soukoulis, Samyukta Reddy, Ryan D. Pooley, Yuanyi Feng, Christopher A. Walsh, David M. Bader

Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24): 8549–8554. Published online 2005 Jun 6. doi: 10.1073/pnas.0502303102

PMCID:: PMC1150833

Abstract Article PDF–834K

Select item 40485436.

The expression and roles of Nde1 and Ndel1 in the adult mammalian central nervous system

Z. Pei, B. Lang, Y.D. Fragoso, K.D. Shearer, L. Zhao, P.J.A. Mccaffery, S. Shen, Y.Q. Ding, C.D. McCaig, J.M. Collinson

Neuroscience. 2014 Jun 20; 271(100): 119–136. doi: 10.1016/j.neuroscience.2014.04.031

PMCID:: PMC4048543

Abstract Article PDF–6.1M

Select item 31010967.

The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein

Eliza Żyłkiewicz, Monika Kijańska, Won-Chan Choi, Urszula Derewenda, Zygmunt S. Derewenda, P. Todd Stukenberg

J Cell Biol. 2011 Feb 7; 192(3): 433–445. doi: 10.1083/jcb.201011142

PMCID:: PMC3101096

Abstract Article PDF–2.7M

Select item 30770888.

Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry

Sehyun Kim, Norann A. Zaghloul, Ekaterina Bubenshchikova, Edwin C. Oh, Susannah Rankin, Nicholas Katsanis, Tomoko Obara, Leonidas Tsiokas

Nat Cell Biol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Nat Cell Biol. 2011 Apr; 13(4): 351–360. Published online 2011 Mar 13. doi: 10.1038/ncb2183

PMCID:: PMC3077088

Abstract Article PDF–1.8M

Select item 28083739.

Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity

Anat Shmueli, Michal Segal, Tamar Sapir, Ryouhei Tsutsumi, Jun Noritake, Avi Bar, Sivan Sapoznik, Yuko Fukata, Irit Orr, Masaki Fukata, Orly Reiner

EMBO J. 2010 Jan 6; 29(1): 107–119. Published online 2009 Nov 19. doi: 10.1038/emboj.2009.325

PMCID:: PMC2808373

Abstract Article PDF–2.0M

Select item 460166310.

Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length

Dipak Maskey, Matthew Caleb Marlin, Seokho Kim, Sehyun Kim, E-Ching Ong, Guangpu Li, Leonidas Tsiokas

EMBO J. 2015 Oct 1; 34(19): 2424–2440. Published online 2015 Jul 23. doi: 10.15252/embj.201490831

PMCID:: PMC4601663

Abstract Article PDF–3.4M

Select item 314671611.

The Essential Role of Centrosomal NDE1 in Human Cerebral Cortex Neurogenesis

Mehmet Bakircioglu, Ofélia P. Carvalho, Maryam Khurshid, James J. Cox, Beyhan Tuysuz, Tanyeri Barak, Saliha Yilmaz, Okay Caglayan, Alp Dincer, Adeline K. Nicholas, Oliver Quarrell, Kelly Springell, Gulshan Karbani, Saghira Malik, Caroline Gannon, Eamonn Sheridan, Moira Crosier, Steve N. Lisgo, Susan Lindsay, Kaya Bilguvar, Fanni Gergely, Murat Gunel, C. Geoffrey Woods

Am J Hum Genet. 2011 May 13; 88(5): 523–535. doi: 10.1016/j.ajhg.2011.03.019

PMCID:: PMC3146716

Abstract Article PDF–1.7M

Select item 532227412.

A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling

M Fujitani, S Zhang, R Fujiki, Y Fujihara, T Yamashita

Mol Psychiatry. 2017 Mar; 22(3): 364–374. Published online 2016 Jul 5. doi: 10.1038/mp.2016.106

PMCID:: PMC5322274

Abstract Article PDF–773K

Select item 119028213.

Complete Loss of Ndel1 Results in Neuronal Migration Defects and Early Embryonic Lethality

Shinji Sasaki, Daisuke Mori, Kazuhito Toyo-oka, Amy Chen, Lisa Garrett-Beal, Masami Muramatsu, Shuji Miyagawa, Noriko Hiraiwa, Atsushi Yoshiki, Anthony Wynshaw-Boris, Shinji Hirotsune

Mol Cell Biol. 2005 Sep; 25(17): 7812–7827. doi: 10.1128/MCB.25.17.7812-7827.2005

PMCID:: PMC1190282

Abstract Article PDF–1.8M

Select item 323478414.

Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin

Richard J. McKenney, Sarah J. Weil, Julian Scherer, Richard B. Vallee

J Biol Chem. 2011 Nov 11; 286(45): 39615–39622. Published online 2011 Sep 12. doi: 10.1074/jbc.M111.289017

PMCID:: PMC3234784

Abstract Article PDF–1.7M

Select item 417021115.

The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation

Shauna L Houlihan, Yuanyi Feng

eLife. 2014; 3: e03297. Published online 2014 Sep 23. doi: 10.7554/eLife.03297

PMCID:: PMC4170211

Abstract Article PDF–4.7M

Select item 912132816.

Nde1 is required for heterochromatin compaction and stability in neocortical neurons

Alison A. Chomiak, Yan Guo, Caroline A. Kopsidas, Dennis P. McDaniel, Clara C. Lowe, Hongna Pan, Xiaoming Zhou, Qiong Zhou, Martin L. Doughty, Yuanyi Feng

iScience. 2022 Jun 17; 25(6): 104354. Published online 2022 May 5. doi: 10.1016/j.isci.2022.104354