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Select item 79541311.

Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome

Steven J. Forrester, Qian Xu, Daniel S. Kikuchi, Derick Okwan-Duodu, Ana Carolina Campos, Elizabeth A. Faidley, Guogang Zhang, Bernard Lassègue, Ruxana T. Sadikot, Kathy K. Griendling, Marina S. Hernandes

Clin Sci (Lond) Author manuscript; available in PMC 2021 Mar 12.

Published in final edited form as: Clin Sci (Lond). 2019 Jan 31; 133(2): 321–334. Published online 2019 Jan 25. doi: 10.1042/CS20180944

PMCID:: PMC7954131

Abstract Article PDF–1.1M

Select item 68836762.

Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy

Daniel S. Kikuchi, Ana Carolina P. Campos, Hongyan Qu, Steven J. Forrester, Rosana L. Pagano, Bernard Lassègue, Ruxana T. Sadikot, Kathy K. Griendling, Marina S. Hernandes

J Neuroinflammation. 2019; 16: 241. Published online 2019 Nov 28. doi: 10.1186/s12974-019-1575-4

PMCID:: PMC6883676

Abstract Article PDF–1.7M

Select item 58163953.

Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain

Marina S. Hernandes, Bernard Lassègue, Lula L. Hilenski, Jonathan Adams, Ning Gao, Chia-Yi Kuan, Yu-Yo Sun, Lihong Cheng, Daniel S. Kikuchi, Manuel Yepes, Kathy K. Griendling

J Neuroinflammation. 2018; 15: 45. Published online 2018 Feb 17. doi: 10.1186/s12974-017-1032-1

PMCID:: PMC5816395

Abstract Article PDF–1.2M

Select item 41464584.

Poldip2 promotes postischemic neovascularization of the mouse hindlimb

Angélica M. Amanso, Bernard Lassègue, Giji Joseph, Natalia Landázuri, James S. Long, Daiana Weiss, W. Robert Taylor, Kathy K. Griendling

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Jul; 34(7): 1548–1555. Published online 2014 May 22. doi: 10.1161/ATVBAHA.114.303873

PMCID:: PMC4146458

Abstract Article PDF–382K

Select item 102684345.

Metabolic regulation of the proteasome under hypoxia by Poldip2 controls fibrotic signaling in vascular smooth muscle cells

Felipe Paredes, Holly C. Williams, Izabela Suster, Macarena Tejos, Roberto Fuentealba, Bethany Bogan, Claire M. Holden, Alejandra San Martin

Free Radic Biol Med. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Free Radic Biol Med. 2023 Feb 1; 195: 283–297. Published online 2022 Dec 31. doi: 10.1016/j.freeradbiomed.2022.12.098

PMCID:: PMC10268434

Abstract Article PDF–3.5M

Select item 96127956.

Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation

Elena V Dolmatova, Steven J Forrester, Keke Wang, Ziwei Ou, Holly C Williams, Giji Joseph, Sandeep Kumar, Alejandra Valdivia, Andrew P Kowalczyk, Hongyan Qu, Hanjoong Jo, Bernard Lassègue, Marina S Hernandes, Kathy K Griendling

Cardiovasc Res. 2022 Jul; 118(11): 2506–2518. Published online 2021 Sep 16. doi: 10.1093/cvr/cvab295

PMCID:: PMC9612795

Abstract Article PDF–2.1M

Select item 92385497.

Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome

Ziwei Ou, Elena Dolmatova, Rohan Mandavilli, Hongyan Qu, Georgette Gafford, Taylor White, Alejandra Valdivia, Bernard Lassègue, Marina S. Hernandes, Kathy K. Griendling

J Am Heart Assoc. 2022 May 17; 11(10): e025181. Published online 2022 May 10. doi: 10.1161/JAHA.121.025181

PMCID:: PMC9238549

Abstract Article PDF–13M

Select item 86875308.

Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting

Bernard Lassègue, Sandeep Kumar, Rohan Mandavilli, Keke Wang, Michelle Tsai, Dong-Won Kang, Catherine Demos, Marina S. Hernandes, Alejandra San Martín, W. Robert Taylor, Hanjoong Jo, Kathy K. Griendling

PLoS One. 2021; 16(12): e0247261. Published online 2021 Dec 20. doi: 10.1371/journal.pone.0247261

PMCID:: PMC8687530

Abstract Article PDF–4.4M

Select item 72519649.

Mitochondrial Protein Poldip2 Controls VSMC Differentiated Phenotype by O-Linked GlcNAc Transferase-Dependent Inhibition of a Ubiquitin Proteasome System

Felipe Paredes, Holly C. Williams, Raymundo A. Quintana, Alejandra San Martin

Circ Res. Author manuscript; available in PMC 2021 Jan 3.

Published in final edited form as: Circ Res. 2020 Jan 3; 126(1): 41–56. Published online 2019 Oct 28. doi: 10.1161/CIRCRESAHA.119.315932

PMCID:: PMC7251964

Abstract Article PDF–1.7M

Select item 639316610.

Poldip2 Knockdown Inhibits Vascular Smooth Muscle Proliferation and Neointima Formation by Regulating the Expression of PCNA and p21

Srinivasa Raju Datla, Lula Hilenski, Bonnie Seidel-Rogol, Anna E. Dikalova, Mark Harousseau, Lili Punkova, Giji Joseph, W. Robert Taylor, Bernard Lassègue, Kathy K. Griendling

Lab Invest. Author manuscript; available in PMC 2019 Mar 20.

Published in final edited form as: Lab Invest. 2019 Mar; 99(3): 387–398. Published online 2018 Sep 20. doi: 10.1038/s41374-018-0103-y

PMCID:: PMC6393166

Abstract Article PDF–3.4M

Select item 582862711.

Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer

Felipe Paredes, Kely Sheldon, Bernard Lassègue, Holly C. Williams, Elizabeth A. Faidley, Gloria A. Benavides, Gloria Torres, Fernanda Sanhueza-Olivares, Samantha M. Yeligar, Kathy K. Griendling, Victor Darley-Usmar, Alejandra San Martin

Proc Natl Acad Sci U S A. 2018 Feb 20; 115(8): 1789–1794. Published online 2018 Feb 6. doi: 10.1073/pnas.1720693115

PMCID:: PMC5828627

Abstract Article PDF–1.1M

Select item 401052912.

Poldip2 Knockout Results in Perinatal Lethality, Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts

David I. Brown, Bernard Lassègue, Minyoung Lee, Rostam Zafari, James S. Long, Harold I. Saavedra, Kathy K. Griendling

PLoS One. 2014; 9(5): e96657. Published online 2014 May 5. doi: 10.1371/journal.pone.0096657

PMCID:: PMC4010529

Abstract Article PDF–1.5M

Select item 383741413.

Poldip2 sustains vascular structure and function

Roy L. Sutliff, Lula L. Hilenski, Angélica M. Amanso, Ioannis Parastatidis, Anna E. Dikalova, Laura Hansen, Srinivasa Raju Datla, James S. Long, Alexander M. El-Ali, Giji Joseph, Rudolph L. Gleason, Jr., W. Robert Taylor, C. Michael Hart, Kathy K. Griendling, Bernard Lassègue

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Sep; 33(9): 10.1161/ATVBAHA.113.301913. Published online 2013 Jul 3. doi: 10.1161/ATVBAHA.113.301913

Correction in:: volume 33 on page e132

PMCID:: PMC3837414

Abstract Article PDF–3.5M

Select item 797093414.

Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction

Lori N. Eidson, Qingzeng Gao, Hongyan Qu, Daniel S. Kikuchi, Ana Carolina P. Campos, Elizabeth A. Faidley, Yu-Yo Sun, Chia-Yi Kuan, Rosana L. Pagano, Bernard Lassègue, Malú G. Tansey, Kathy K. Griendling, Marina S. Hernandes

Sci Rep. 2021; 11: 5533. Published online 2021 Mar 10. doi: 10.1038/s41598-021-84987-z

PMCID:: PMC7970934

Abstract Article PDF–1.7M

Select item 770223715.

Poldip2 mediates blood‐brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model

Meng Gao, Weitian Lu, Yue Shu, Zhengyu Yang, Shanquan Sun, Jin Xu, Shengwei Gan, Shujuan Zhu, Guoping Qiu, Fei Zhuo, Shiye Xu, Yiying Wang, Junhong Chen, Xuan Wu, Juan Huang

CNS Neurosci Ther. 2020 Dec; 26(12): 1288–1302. Published online 2020 Aug 12. doi: 10.1111/cns.13446

PMCID:: PMC7702237

Abstract Article PDF–2.8M

Select item 482517516.

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

Masakazu Fujii, Angélica Amanso, Thalita B. Abrahão, Bernard Lassègue, Kathy K. Griendling

J Mol Cell Cardiol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: J Mol Cell Cardiol. 2016 Mar; 92: 21–29. Published online 2016 Jan 19. doi: 10.1016/j.yjmcc.2016.01.016

PMCID:: PMC4825175

Abstract Article PDF–1.3M

Select item 658016217.

Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells

Lauren Parker Huff, Daniel Seicho Kikuchi, Elizabeth Faidley, Steven J. Forrester, Michelle Z. Tsai, Bernard Lassègue, Kathy K. Griendling

Am J Physiol Cell Physiol. 2019 May 1; 316(5): C621–C631. Published online 2019 Feb 6. doi: 10.1152/ajpcell.00208.2018

PMCID:: PMC6580162

Abstract Article

Select item 629804018.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 538122619.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 277884420.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

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