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Select item 85730691.

Deficiency of MicroRNA-181a Results in Transcriptome-Wide Cell-Specific Changes in the Kidney and Increases Blood Pressure

Madeleine R. Paterson, Kristy L. Jackson, Malathi S. I. Dona, Gabriella E. Farrugia, Bruna Visniauskas, Anna M. D. Watson, Chad Johnson, Minolfa C. Prieto, Roger G. Evans, Fadi Charchar, Alexander R. Pinto, Francine Z. Marques, Geoffrey A. Head

Hypertension. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Hypertension. 2021 Nov; 78(5): 1322–1334. Published online 2021 Sep 20. doi: 10.1161/HYPERTENSIONAHA.121.17384

PMCID:: PMC8573069

Abstract Article PDF–1.5M

Select item 70078872.

MicroRNA-181a regulates IFN-γ expression in effector CD8⁺ T cell differentiation

Tiago Amado, Ana Amorim, Francisco J. Enguita, Paula V. Romero, Daniel Inácio, Marta Pires de Miranda, Samantha J. Winter, J. Pedro Simas, Andreas Krueger, Nina Schmolka, Bruno Silva-Santos, Anita Q. Gomes

J Mol Med (Berl) 2020; 98(2): 309–320. Published online 2020 Jan 30. doi: 10.1007/s00109-019-01865-y

PMCID:: PMC7007887

Abstract Article PDF–850K

Select item 67384343.

MicroRNA-181a protects against pericyte apoptosis via directly targeting FOXO1: implication for ameliorated cognitive deficits in APP/PS1 mice

Qingbin Wu, Xiaochen Yuan, Jing Bai, Ruiqin Han, Zhigang Li, Honggang Zhang, Ruijuan Xiu

Aging (Albany NY) 2019 Aug 31; 11(16): 6120–6133. Published online 2019 Aug 29. doi: 10.18632/aging.102171

PMCID:: PMC6738434

Abstract Article PDF–1.6M

Select item 36041754.

MicroRNA-181a Suppresses Mouse Granulosa Cell Proliferation by Targeting Activin Receptor IIA

Qun Zhang, Haixiang Sun, Yue Jiang, Lijun Ding, Shaogen Wu, Ting Fang, Guijun Yan, Yali Hu

PLoS One. 2013; 8(3): e59667. Published online 2013 Mar 20. doi: 10.1371/journal.pone.0059667

PMCID:: PMC3604175

Abstract Article PDF–1.4M

Select item 104336305.

miR-181a-5p targets DDX3X to inhibit the progression of osteoarthritis via NF-ΚB signaling pathway

Peng Zhao, Guobin Ma, Lintong Ma

J Orthop Surg Res. 2023; 18: 606. Published online 2023 Aug 16. doi: 10.1186/s13018-023-04073-0

PMCID:: PMC10433630

Abstract Article PDF–2.0M

Select item 85439366.

miR-181a regulates the host immune response against Schistosoma japonicum infection through the TLR4 receptor pathway

Yixiao Tang, Yuanxi Shen, Yang Hong, Zuhang Zhang, Qi Zhai, Zhiqiang Fu, Hao Li, Ke Lu, Jiaojiao Lin

Parasit Vectors. 2021; 14: 548. Published online 2021 Oct 24. doi: 10.1186/s13071-021-05063-z

PMCID:: PMC8543936

Abstract Article PDF–1.4M

Select item 69572317.

Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency

Chulwoo Kim, Rohit R. Jadhav, Claire E. Gustafson, Megan J. Smithey, Alec J. Hirsch, Jennifer L. Uhrlaub, William H. Hildebrand, Janko Nikolich-Žugich, Cornelia M. Weyand, Jörg J. Goronzy

Cell Rep. Author manuscript; available in PMC 2020 Jan 13.

Published in final edited form as: Cell Rep. 2019 Nov 19; 29(8): 2202–2216.e5. doi: 10.1016/j.celrep.2019.10.044

PMCID:: PMC6957231

Abstract Article PDF–2.3M

Select item 60210628.

Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development

Heather E. Stefanski, Yan Xing, Patricia A. Taylor, Stefano Maio, Jorge Henao-Meija, Adam Williams, Richard A. Flavell, Georg A. Hollander, Bruce R. Blazar

PLoS One. 2018; 13(6): e0198871. Published online 2018 Jun 27. doi: 10.1371/journal.pone.0198871

PMCID:: PMC6021062

Abstract Article PDF–5.3M

Select item 37624839.

An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

Peter J R Ebert, Shan Jiang, Jianming Xie, Qi-Jing Li, Mark M Davis

Nat Immunol. Author manuscript; available in PMC 2013 Sep 4.

Published in final edited form as: Nat Immunol. 2009 Nov; 10(11): 1162–1169. Published online 2009 Oct 4. doi: 10.1038/ni.1797

PMCID:: PMC3762483

Abstract Article PDF–1.5M

Select item 364553310.

Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells

Natalia Ziętara, Marcin Łyszkiewicz, Katrin Witzlau, Ronald Naumann, Robert Hurwitz, Jörg Langemeier, Jens Bohne, Inga Sandrock, Matthias Ballmaier, Siegfried Weiss, Immo Prinz, Andreas Krueger

Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18): 7407–7412. Published online 2013 Apr 15. doi: 10.1073/pnas.1221984110

PMCID:: PMC3645533

Abstract Article PDF–887K

Select item 1000866811.

MicroRNA-181a-5p Curbs Osteogenic Differentiation and Bone Formation Partially Through Impairing Runx1-Dependent Inhibition of AIF-1 Transcription

Jingwei Liu, Xueying Chang, Daming Dong

Endocrinol Metab (Seoul) 2023 Feb; 38(1): 156–173. Published online 2023 Jan 6. doi: 10.3803/EnM.2022.1516

PMCID:: PMC10008668

Abstract Article PDF–2.6M

Select item 997030712.

MiR-181a-5p promotes osteogenesis by targeting BMP3

Ze Long, Pengcheng Dou, Weiliang Cai, Minzhi Mao, Ren Wu

Aging (Albany NY) 2023 Feb 14; 15(3): 734–747. Published online 2023 Feb 3. doi: 10.18632/aging.204505

PMCID:: PMC9970307

Abstract Article PDF–2.0M

Select item 705914213.

miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease

Carlos J. Rodriguez‐Ortiz, Gilberto Aleph Prieto, Alessandra C. Martini, Stefania Forner, Laura Trujillo‐Estrada, Frank M. LaFerla, David Baglietto‐Vargas, Carl W. Cotman, Masashi Kitazawa

Aging Cell. 2020 Mar; 19(3): e13118. Published online 2020 Feb 22. doi: 10.1111/acel.13118

PMCID:: PMC7059142

Abstract Article PDF–1.2M

Select item 420796814.

Transglutaminase II/MicroRNA-218/-181a Loop Regulates Positive Feedback Relationship between Allergic Inflammation and Tumor Metastasis

Sangkyung Eom, Youngmi Kim, Misun Kim, Deokbum Park, Hansoo Lee, Yun Sil Lee, Jongseon Choe, Young Myeong Kim, Dooil Jeoung

J Biol Chem. 2014 Oct 24; 289(43): 29483–29505. Published online 2014 Sep 8. doi: 10.1074/jbc.M114.603480

PMCID:: PMC4207968

Abstract Article PDF–8.8M

Select item 596640015.

Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity

Xiao-Yun Liu, Fei-Ran Zhang, Jin-Yan Shang, Ying-Ying Liu, Xiao-Fei Lv, Jia-Ni Yuan, Ting-Ting Zhang, Kai Li, Xiao-Chun Lin, Xiu Liu, Qingqing Lei, Xiao-Dong Fu, Jia-Guo Zhou, Si-Jia Liang

Cell Death Dis. 2018 Jun; 9(6): 610. Published online 2018 May 23. doi: 10.1038/s41419-018-0677-8

PMCID:: PMC5966400

Abstract Article PDF–8.3M

Select item 341543316.

Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1

Rita Fragoso, Tin Mao, Song Wang, Steven Schaffert, Xue Gong, Sibiao Yue, Richard Luong, Hyeyoung Min, Yumi Yashiro-Ohtani, Mark Davis, Warren Pear, Chang-Zheng Chen

PLoS Genet. 2012 Aug; 8(8): e1002855. Published online 2012 Aug 9. doi: 10.1371/journal.pgen.1002855

PMCID:: PMC3415433

Abstract Article PDF–2.9M

Select item 325056117.

miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes

Yi-Bing Ouyang, Yu Lu, Sibiao Yue, Rona G. Giffard

Mitochondrion. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Mitochondrion. 2012 Mar; 12(2): 213–219. Published online 2011 Sep 17. doi: 10.1016/j.mito.2011.09.001

PMCID:: PMC3250561

Abstract Article PDF–1.8M

Select item 650568518.

miR‐181a/b downregulation exerts a protective action on mitochondrial disease models

Alessia Indrieri, Sabrina Carrella, Alessia Romano, Alessandra Spaziano, Elena Marrocco, Erika Fernandez‐Vizarra, Sara Barbato, Mariateresa Pizzo, Yulia Ezhova, Francesca M Golia, Ludovica Ciampi, Roberta Tammaro, Jorge Henao‐Mejia, Adam Williams, Richard A Flavell, Elvira De Leonibus, Massimo Zeviani, Enrico M Surace, Sandro Banfi, Brunella Franco

EMBO Mol Med. 2019 May; 11(5): e8734. Published online 2019 Apr 12. doi: 10.15252/emmm.201708734

PMCID:: PMC6505685

Abstract Article PDF–4.3M

Select item 1080550219.

Intermittent hypoxia increased the expression of ESM1 and ICAM‐1 in vascular endothelial cells via the downregulation of microRNA‐181a1

Shin Takasawa, Mai Makino, Akiyo Yamauchi, Sumiyo Sakuramoto‐Tsuchida, Rina Hirota, Ryusei Fujii, Keito Asai, Yoshinori Takeda, Tomoko Uchiyama, Ryogo Shobatake, Hiroyo Ota

J Cell Mol Med. 2024 Jan; 28(1): e18039. Published online 2023 Nov 15. doi: 10.1111/jcmm.18039

PMCID:: PMC10805502

Abstract Article PDF–582K

Select item 710892820.

The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas

Karmele Valencia, Oihane Erice, Kaja Kostyrko, Simone Hausmann, Elizabeth Guruceaga, Anuradha Tathireddy, Natasha M. Flores, Leanne C. Sayles, Alex G. Lee, Rita Fragoso, Tian-Qiang Sun, Adrian Vallejo, Marta Roman, Rodrigo Entrialgo-Cadierno, Itziar Migueliz, Nerea Razquin, Puri Fortes, Fernando Lecanda, Jun Lu, Mariano Ponz-Sarvise, Chang-Zheng Chen, Pawel K. Mazur, E. Alejandro Sweet-Cordero, Silvestre Vicent

J Clin Invest. 2020 Apr 1; 130(4): 1879–1895. Published online 2020 Mar 9. doi: 10.1172/JCI129012

PMCID:: PMC7108928

Abstract Article PDF–13M

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