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Items: 1 to 20 of 24

1.
Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway
Yunjian Liu, Hyeong Geug Kim, Edward Dong, Chuanpeng Dong, Menghao Huang, Yunlong Liu, Suthat Liangpunsakul, Xiaocheng Charlie Dong
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1; 1865(10): 2685–2693. Published online 2019 Jul 24. doi: 10.1016/j.bbadis.2019.07.011
PMCID:
PMC6708743
AbstractArticlePDF–909K
2.
Sestrins induce natural killer function in senescent-like CD8+ T cells
Branca I. Pereira, Roel P. H. De Maeyer, Luciana P. Covre, Djamel Nehar-Belaid, Alessio Lanna, Sophie Ward, Radu Marches, Emma S. Chambers, Daniel C. O. Gomes, Natalie E. Riddell, Mala K. Maini, Vitor H. Teixeira, Samuel M. Janes, Derek W. Gilroy, Anis Larbi, Neil A. Mabbott, Duygu Ucar, George A. Kuchel, Sian M. Henson, Jessica Strid, Jun H. Lee, Jacques Banchereau, Arne N. Akbar
Nat Immunol. Author manuscript; available in PMC 2023 Jun 8.
Published in final edited form as: Nat Immunol. 2020 Jun; 21(6): 684–694. Published online 2020 Mar 30. doi: 10.1038/s41590-020-0643-3
PMCID:
PMC10249464
AbstractArticlePDF–4.1M
3.
SESN3 Inhibited SMAD3 to Relieve Its Suppression for MiR-124, Thus Regulating Pre-Adipocyte Adipogenesis
Weimin Lin, Jindi Zhao, Mengting Yan, Xuexin Li, Kai Yang, Wei Wei, Lifan Zhang, Jie Chen
Genes (Basel) 2021 Dec; 12(12): 1852. Published online 2021 Nov 23. doi: 10.3390/genes12121852
PMCID:
PMC8701261
AbstractArticlePDF–5.1M
4.
The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injury
Xinqin Kang, Kateryna Petyaykina, Rongya Tao, Xiwen Xiong, X. Charlie Dong, Suthat Liangpunsakul
Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1; 307(1): G58–G65. Published online 2014 May 15. doi: 10.1152/ajpgi.00373.2013
PMCID:
PMC4080163
AbstractArticle
5.
Sestrins orchestrate cellular metabolism to attenuate aging
Jun Hee Lee, Andrei V. Budanov, Michael Karin
Cell Metab. Author manuscript; available in PMC 2014 Dec 3.
Published in final edited form as: Cell Metab. 2013 Dec 3; 18(6): 10.1016/j.cmet.2013.08.018. Published online 2013 Sep 19. doi: 10.1016/j.cmet.2013.08.018
PMCID:
PMC3858445
AbstractArticlePDF–1.9M
6.
Sestrin1, 2, and 3 are dispensable for female fertility in mice
Mengchen Wang, Wenhui Chen, Xinxin Zeng, Taojun Wang, Yingpu Sun, Qingling Yang
J Ovarian Res. 2024; 17: 28. Published online 2024 Feb 1. doi: 10.1186/s13048-024-01345-z
PMCID:
PMC10832176
AbstractArticlePDF–4.8M
7.
Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis
Seung-Hyun Ro, Xiang Xue, Sadeesh K Ramakrishnan, Chun-Seok Cho, Sim Namkoong, Insook Jang, Ian A Semple, Allison Ho, Hwan-Woo Park, Yatrik M Shah, Jun Hee Lee
eLife. 2016; 5: e12204. Published online 2016 Feb 25. doi: 10.7554/eLife.12204
PMCID:
PMC4805551
AbstractArticlePDF–4.1M
8.
Sestrin 3 Protein Enhances Hepatic Insulin Sensitivity by Direct Activation of the mTORC2-Akt Signaling
Rongya Tao, Xiwen Xiong, Suthat Liangpunsakul, X. Charlie Dong
Diabetes. 2015 Apr; 64(4): 1211–1223. Published online 2014 Nov 4. doi: 10.2337/db14-0539
PMCID:
PMC4375082
AbstractArticlePDF–2.1M
9.
Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling
Min Peng, Na Yin, Ming O. Li
Cell. Author manuscript; available in PMC 2015 Sep 25.
Published in final edited form as: Cell. 2014 Sep 25; 159(1): 122–133. doi: 10.1016/j.cell.2014.08.038
PMCID:
PMC4181352
AbstractArticlePDF–2.7M
10.
FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor
Chia-Chen Chen, Sang-Min Jeon, Prashanth T. Bhaskar, Veronique Nogueira, Deepa Sundararajan, Ivana Tonic, Youngkyu Park, Nissim Hay
Dev Cell. Author manuscript; available in PMC 2011 Apr 20.
Published in final edited form as: Dev Cell. 2010 Apr 20; 18(4): 592–604. doi: 10.1016/j.devcel.2010.03.008
PMCID:
PMC3031984
AbstractArticlePDF–1.5M
11.
Sestrins are evolutionarily conserved mediators of exercise benefits
Myungjin Kim, Alyson Sujkowski, Sim Namkoong, Bondong Gu, Tyler Cobb, Boyoung Kim, Allison H. Kowalsky, Chun-Seok Cho, Ian Semple, Seung-Hyun Ro, Carol Davis, Susan V. Brooks, Michael Karin, Robert J. Wessells, Jun Hee Lee
Nat Commun. 2020; 11: 190. Published online 2020 Jan 13. doi: 10.1038/s41467-019-13442-5
PMCID:
PMC6955242
AbstractArticlePDF–2.4M
12.
Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo
Boris Klimovich, Thorsten Stiewe, Oleg Timofeev
Cell Cycle. 2020; 19(1): 109–123. Published online 2019 Nov 21. doi: 10.1080/15384101.2019.1693748
PMCID:
PMC6927723
AbstractArticlePDF–3.9M
13.
Maintenance of metabolic homeostasis by Sestrin 2 and 3
Jun Hee Lee, Andrei V. Budanov, Saswata Talukdar, Eek Joong Park, Hae Li Park, Hwan-Woo Park, Gautam Bandyopadhyay, Ning Li, Mariam Aghajan, Insook Jang, Amber M. Wolfe, Guy A. Perkins, Mark H. Ellisman, Ethan Bier, Miriam Scadeng, Marc Foretz, Benoit Viollet, Jerrold Olefsky, Michael Karin
Cell Metab. Author manuscript; available in PMC 2013 Jun 20.
Published in final edited form as: Cell Metab. 2012 Sep 5; 16(3): 311–321. doi: 10.1016/j.cmet.2012.08.004
PMCID:
PMC3687365
AbstractArticlePDF–5.0M
14.
A gene expression resource generated by genome-wide lacZ profiling in the mouse
Elizabeth Tuck, Jeanne Estabel, Anika Oellrich, Anna Karin Maguire, Hibret A. Adissu, Luke Souter, Emma Siragher, Charlotte Lillistone, Angela L. Green, Hannah Wardle-Jones, Damian M. Carragher, Natasha A. Karp, Damian Smedley, Niels C. Adams, Sanger Institute Mouse Genetics Project, James N. Bussell, David J. Adams, Ramiro Ramírez-Solis, Karen P. Steel, Antonella Galli, Jacqueline K. White
Dis Model Mech. 2015 Nov 1; 8(11): 1467–1478. doi: 10.1242/dmm.021238
PMCID:
PMC4631787
AbstractArticle
15.
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives
Owen J Tamplin, Doris Kinzel, Brian J Cox, Christine E Bell, Janet Rossant, Heiko Lickert
BMC Genomics. 2008; 9: 511. Published online 2008 Oct 30. doi: 10.1186/1471-2164-9-511
PMCID:
PMC2605479
AbstractArticlePDF–1.7M
16.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
17.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
18.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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