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Select item 108581801.

Developmental loss of NMDA receptors results in supernumerary forebrain neurons through delayed maturation of transit-amplifying neuroblasts

Amalia J. Napoli, Stephanie Laderwager, Josiah D. Zoodsma, Bismi Biju, Olgerta Mucollari, Sarah K. Schubel, Christieann Aprea, Aaliya Sayed, Kiele Morgan, Annelysia Napoli, Stephanie Flanagan, Lonnie P. Wollmuth, Howard I. Sirotkin

Sci Rep. 2024; 14: 3395. Published online 2024 Feb 9. doi: 10.1038/s41598-024-53910-7

PMCID:: PMC10858180

Abstract Article PDF–9.5M

Select item 71897612.

A Model to Study NMDA Receptors in Early Nervous System Development

Josiah D. Zoodsma, Kelvin Chan, Ashwin A. Bhandiwad, David R. Golann, Guangmei Liu, Shoaib A. Syed, Amalia J. Napoli, Harold A. Burgess, Howard I. Sirotkin, Lonnie P. Wollmuth

J Neurosci. 2020 Apr 29; 40(18): 3631–3645. doi: 10.1523/JNEUROSCI.3025-19.2020

PMCID:: PMC7189761

Abstract Article PDF–3.4M

Select item 82973053.

Developmental Neurotoxicity of Environmentally Relevant Pharmaceuticals and Mixtures Thereof in a Zebrafish Embryo Behavioural Test

Alessandro Atzei, Ingrid Jense, Edwin P. Zwart, Jessica Legradi, Bastiaan J. Venhuis, Leo T.M. van der Ven, Harm J. Heusinkveld, Ellen V.S. Hessel

Int J Environ Res Public Health. 2021 Jul; 18(13): 6717. Published online 2021 Jun 22. doi: 10.3390/ijerph18136717

PMCID:: PMC8297305

Abstract Article PDF–2.5M

Select item 59523054.

The Midline Axon Crossing Decision Is Regulated through an Activity-Dependent Mechanism by the NMDA Receptor

Jingxia Gao, Tamara J. Stevenson, Adam D. Douglass, Joshua P. Barrios, Joshua L. Bonkowsky

eNeuro. 2018 Mar-Apr; 5(2): ENEURO.0389-17.2018. Prepublished online 2018 Apr 16. Published online 2018 Apr 17. doi: 10.1523/ENEURO.0389-17.2018

PMCID:: PMC5952305

Abstract Article PDF–2.1M

Select item 25762225.

Synaptic Homeostasis in a Zebrafish Glial Glycine Transporter Mutant

Rebecca Mongeon, Michelle R. Gleason, Mark A. Masino, Joseph R. Fetcho, Gail Mandel, Paul Brehm, Julia E. Dallman

J Neurophysiol. 2008 Oct; 100(4): 1716–1723. Published online 2008 Aug 20. doi: 10.1152/jn.90596.2008

PMCID:: PMC2576222

Abstract Article

Select item 83050446.

6-Gingerol, a Major Constituent of Zingiber officinale Rhizoma, Exerts Anticonvulsant Activity in the Pentylenetetrazole-Induced Seizure Model in Larval Zebrafish

Kinga Gawel, Wirginia Kukula-Koch, Nancy Saana Banono, Dorota Nieoczym, Katarzyna M. Targowska-Duda, Lidia Czernicka, Jolanta Parada-Turska, Camila V. Esguerra

Int J Mol Sci. 2021 Jul; 22(14): 7745. Published online 2021 Jul 20. doi: 10.3390/ijms22147745

PMCID:: PMC8305044

Abstract Article PDF–5.6M

Select item 34184507.

A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors

Robert F. Hunt, Gabriela A. Hortopan, Anna Gillespie, Scott C. Baraban

Exp Neurol. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Exp Neurol. 2012 Sep; 237(1): 199–206. Published online 2012 Jun 24. doi: 10.1016/j.expneurol.2012.06.013

PMCID:: PMC3418450

Abstract Article PDF–774K

Select item 95029588.

Disruption of grin2B, an ASD-associated gene, produces social deficits in zebrafish

Josiah D. Zoodsma, Emma J. Keegan, Gabrielle R. Moody, Ashwin A. Bhandiwad, Amalia J. Napoli, Harold A. Burgess, Lonnie P. Wollmuth, Howard I. Sirotkin

Mol Autism. 2022; 13: 38. Published online 2022 Sep 22. doi: 10.1186/s13229-022-00516-3

PMCID:: PMC9502958

Abstract Article PDF–6.2M

Select item 38820569.

Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1

Peter K. Todd, Feras Y. Ackall, Junguk Hur, Kush Sharma, Henry L. Paulson, James J. Dowling

Dis Model Mech. 2014 Jan; 7(1): 143–155. Published online 2013 Oct 2. doi: 10.1242/dmm.012427

PMCID:: PMC3882056

Abstract Article

Select item 1011716210.

Methylenetetrahydrofolate reductase deficiency and high-dose FA supplementation disrupt embryonic development of energy balance and metabolic homeostasis in zebrafish

Rebecca Simonian, Emanuela Pannia, Rola Hammoud, Ramil R Noche, Xiucheng Cui, Eva Kranenburg, Ruslan Kubant, Paula Ashcraft, Brandi Wasek, Teodoro Bottiglieri, James J Dowling, G Harvey Anderson

Hum Mol Genet. 2023 May 1; 32(9): 1575–1588. Published online 2023 Jan 13. doi: 10.1093/hmg/ddac308

PMCID:: PMC10117162

Abstract Article PDF–1.7M

Select item 809627311.

Systematic identification of A-to-I RNA editing in zebrafish development and adult organs

Ilana Buchumenski, Karoline Holler, Lior Appelbaum, Eli Eisenberg, Jan Philipp Junker, Erez Y Levanon

Nucleic Acids Res. 2021 May 7; 49(8): 4325–4337. Published online 2021 Apr 19. doi: 10.1093/nar/gkab247

PMCID:: PMC8096273

Abstract Article PDF–3.0M

Select item 613088312.

Pharmacologic rescue of hyperammonemia-induced toxicity in zebrafish by inhibition of ornithine aminotransferase

Matthias Zielonka, Maximilian Breuer, Jürgen Günther Okun, Matthias Carl, Georg Friedrich Hoffmann, Stefan Kölker

PLoS One. 2018; 13(9): e0203707. Published online 2018 Sep 10. doi: 10.1371/journal.pone.0203707

PMCID:: PMC6130883

Abstract Article PDF–19M

Select item 846246213.

Social Deficits and Repetitive Behaviors Are Improved by Early Postnatal Low-Dose VPA Intervention in a Novel shank3-Deficient Zebrafish Model

Chunxue Liu, Yi Wang, Jingxin Deng, Jia Lin, Chunchun Hu, Qiang Li, Xiu Xu

Front Neurosci. 2021; 15: 682054. Published online 2021 Sep 10. doi: 10.3389/fnins.2021.682054

PMCID:: PMC8462462

Abstract Article PDF–4.3M

Select item 938607014.

Comparative Study of the Molecular Characterization, Evolution, and Structure Modeling of Digestive Lipase Genes Reveals the Different Evolutionary Selection Between Mammals and Fishes

Shu-Lin Tang, Xu-Fang Liang, Shan He, Ling Li, Muhammad Shoaib Alam, Jiaqi Wu

Front Genet. 2022; 13: 909091. Published online 2022 Aug 4. doi: 10.3389/fgene.2022.909091

PMCID:: PMC9386070

Abstract Article PDF–7.1M

Select item 482296815.

Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules

Mark William Lopes, Matthew R. Sapio, Rodrigo B. Leal, Lloyd D. Fricker

PLoS One. 2016; 11(4): e0152905. Published online 2016 Apr 6. doi: 10.1371/journal.pone.0152905

PMCID:: PMC4822968

Abstract Article PDF–1.2M

Select item 1100675116.

Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease

Prabesh Bhattarai, Tamil Iniyan Gunasekaran, Michael E. Belloy, Dolly Reyes-Dumeyer, Dörthe Jülich, Hüseyin Tayran, Elanur Yilmaz, Delaney Flaherty, Bengisu Turgutalp, Gauthaman Sukumar, Camille Alba, Elisa Martinez McGrath, Daniel N. Hupalo, Dagmar Bacikova, Yann Le Guen, Rafael Lantigua, Martin Medrano, Diones Rivera, Patricia Recio, Tal Nuriel, Nilüfer Ertekin-Taner, Andrew F. Teich, Dennis W. Dickson, Scott Holley, Michael Greicius, Clifton L. Dalgard, Michael Zody, Richard Mayeux, Caghan Kizil, Badri N. Vardarajan

Acta Neuropathol. 2024; 147(1): 70. Published online 2024 Apr 10. doi: 10.1007/s00401-024-02721-1

PMCID:: PMC11006751

Abstract Article PDF–5.2M

Select item 525553517.

Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation

Lavinia Sheets

Sci Rep. 2017; 7: 41102. Published online 2017 Jan 23. doi: 10.1038/srep41102

PMCID:: PMC5255535

Abstract Article PDF–3.0M

Select item 344531118.

Zebrafish rest regulates developmental gene expression but not neurogenesis

Fatma O. Kok, Andrew Taibi, Sarah J. Wanner, Xiayang Xie, Cara E. Moravec, Crystal E. Love, Victoria E. Prince, Jeff S. Mumm, Howard I. Sirotkin

Development. 2012 Oct 15; 139(20): 3838–3848. doi: 10.1242/dev.080994

PMCID:: PMC3445311

Abstract Article

Select item 817570119.

Phenotypic analysis of catastrophic childhood epilepsy genes

Aliesha Griffin, Colleen Carpenter, Jing Liu, Rosalia Paterno, Brian Grone, Kyla Hamling, Maia Moog, Matthew T. Dinday, Francisco Figueroa, Mana Anvar, Chinwendu Ononuju, Tony Qu, Scott C. Baraban

Commun Biol. 2021; 4: 680. Published online 2021 Jun 3. doi: 10.1038/s42003-021-02221-y

PMCID:: PMC8175701

Abstract Article PDF–4.4M

Select item 386081820.

Zebrafish: A Model for the Study of Addiction Genetics

Eric W Klee, Henning Schneider, Karl Clark, Margot Cousin, Jon Ebbert, Michael Hooten, Victor Karpyak, David Warner, Stephen Ekker

Hum Genet. Author manuscript; available in PMC 2013 Dec 12.

Published in final edited form as: Hum Genet. 2012 Jun; 131(6): 10.1007/s00439-011-1128-0. Published online 2011 Dec 30. doi: 10.1007/s00439-011-1128-0

PMCID:: PMC3860818

Abstract Article PDF–367K

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