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Select item 92362781.

Essential function of NHE8 in mouse retina demonstrated by AAV-mediated CRISPR/Cas9 knockdown

Chun-hong Xia, Ian Ferguson, Mei Li, Audrey Kim, Alex Onishi, Lucy Li, Bonnie Su, Xiaohua Gong

Exp Eye Res. Author manuscript; available in PMC 2022 Jun 27.

Published in final edited form as: Exp Eye Res. 2018 Nov; 176: 29–39. Published online 2018 Jun 26. doi: 10.1016/j.exer.2018.06.026

PMCID:: PMC9236278

Abstract Article PDF–2.3M

Select item 76546482.

An indisputable role of NHE8 in mucosal protection

Claudio Bernardazzi, Hua Xu, Huan Tong, Daniel Laubitz, Vanessa Figliuolo da Paz, Leslie Curiel, Fayez K. Ghishan

Am J Physiol Gastrointest Liver Physiol. 2020 Oct 1; 319(4): G421–G431. Published online 2020 Aug 5. doi: 10.1152/ajpgi.00246.2020

PMCID:: PMC7654648

Abstract Article

Select item 46693513.

Loss of NHE8 expression impairs intestinal mucosal integrity

Aiping Wang, Jing Li, Yang Zhao, Malin E. V. Johansson, Hua Xu, Fayez K. Ghishan

Am J Physiol Gastrointest Liver Physiol. 2015 Dec 1; 309(11): G855–G864. Published online 2015 Oct 1. doi: 10.1152/ajpgi.00278.2015

PMCID:: PMC4669351

Abstract Article

Select item 43668484.

NHE8 Is Essential for RPE Cell Polarity and Photoreceptor Survival

Chun-hong Xia, Haiquan Liu, Debra Cheung, Felicia Tang, Bo Chang, Mei Li, Xiaohua Gong

Sci Rep. 2015; 5: 9358. Published online 2015 Mar 20. doi: 10.1038/srep09358

PMCID:: PMC4366848

Abstract Article PDF–2.1M

Select item 43294255.

Disruption of NHE8 expression impairs Leydig cell function in the testes

Hua Xu, Huacong Chen, Jing Li, Yang Zhao, Fayez K. Ghishan

Am J Physiol Cell Physiol. 2015 Feb 15; 308(4): C330–C338. Published online 2014 Dec 4. doi: 10.1152/ajpcell.00289.2014

PMCID:: PMC4329425

Abstract Article

Select item 42816726.

Loss of NHE8 expression impairs ocular surface function in mice

Hua Xu, Yang Zhao, Jing Li, Mingwu Wang, Fangru Lian, Minghong Gao, Fayez K. Ghishan

Am J Physiol Cell Physiol. 2015 Jan 1; 308(1): C79–C87. Published online 2014 Nov 5. doi: 10.1152/ajpcell.00296.2014

PMCID:: PMC4281672

Abstract Article

Select item 37742487.

Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice

Hua Xu, Bo Zhang, Jing Li, Chunhui Wang, Huacong Chen, Fayez K. Ghishan

Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1; 303(3): G335–G343. Published online 2012 May 10. doi: 10.1152/ajpgi.00146.2012

PMCID:: PMC3774248

Abstract Article

Select item 37674548.

Glucocorticoids reduce renal NHE8 expression

Catherine Joseph, Jyothsna Gattineni, Vangipuram Dwarakanath, Michel Baum

Physiol Rep. 2013 Jul; 1(2): e00031. Published online 2013 Jul 15. doi: 10.1002/phy2.31

PMCID:: PMC3767454

Abstract Article PDF–1.1M

Select item 37255199.

NHE8 plays an important role in mucosal protection via its effect on bacterial adhesion

Chang Liu, Hua Xu, Bo Zhang, Malin E. V. Johansson, Jing Li, Gunnar C. Hansson, Fayez K. Ghishan

Am J Physiol Cell Physiol. 2013 Jul 1; 305(1): C121–C128. Published online 2013 May 8. doi: 10.1152/ajpcell.00101.2013

PMCID:: PMC3725519

Abstract Article

Select item 356651310.

NHE8 plays important roles in gastric mucosal protection

Hua Xu, Jing Li, Huacong Chen, Chunhui Wang, Fayez K. Ghishan

Am J Physiol Gastrointest Liver Physiol. 2013 Feb 1; 304(3): G257–G261. Published online 2012 Dec 6. doi: 10.1152/ajpgi.00433.2012

PMCID:: PMC3566513

Abstract Article

Select item 624064411.

NHE8 Deficiency Promotes Colitis-Associated Cancer in Mice via Expansion of Lgr5-Expressing Cells

Hua Xu, Jing Li, Hao Chen, Fayez K. Ghishan

Cell Mol Gastroenterol Hepatol. 2019; 7(1): 19–31. Published online 2018 Aug 24. doi: 10.1016/j.jcmgh.2018.08.005

PMCID:: PMC6240644

Abstract Article PDF–3.9M

Select item 549177112.

Loss of the Na⁺/H⁺ exchanger NHE8 causes male infertility in mice by disrupting acrosome formation

Karina Oberheide, Dmytro Puchkov, Thomas J. Jentsch

J Biol Chem. 2017 Jun 30; 292(26): 10845–10854. Published online 2017 May 5. doi: 10.1074/jbc.M117.784108

PMCID:: PMC5491771

Abstract Article PDF–3.8M

Select item 453896513.

Mouse Slc9a8 Mutants Exhibit Retinal Defects Due to Retinal Pigmented Epithelium Dysfunction

Shalini Jadeja, Alun R. Barnard, Lisa McKie, Sally H. Cross, Jacqueline K. White, on behalf of the Sanger Mouse Genetics Project, Morag Robertson, Peter S. Budd, Robert E. MacLaren, Ian J. Jackson

Invest Ophthalmol Vis Sci. 2015 May; 56(5): 3015–3026. Published online 2015 May 13. doi: 10.1167/iovs.14-15735

PMCID:: PMC4538965

Abstract Article PDF–1.7M

Select item 428169314.

Renal NHE expression and activity in neonatal NHE3- and NHE8-null mice

Kwanchai Pirojsakul, Jyothsna Gattineni, Vangipuram Dwarakanath, Michel Baum

Am J Physiol Renal Physiol. 2015 Jan 1; 308(1): F31–F38. Published online 2014 Nov 5. doi: 10.1152/ajprenal.00492.2014

PMCID:: PMC4281693

Abstract Article

Select item 353248915.

Proximal tubule Na⁺/H⁺ exchanger activity in adult NHE8^−/−, NHE3^−/−, and NHE3^−/−/NHE8^−/− mice

Michel Baum, Katherine Twombley, Jyothsna Gattineni, Catherine Joseph, Lin Wang, Qiuyu Zhang, Vangipuram Dwarakanath, Orson W. Moe

Am J Physiol Renal Physiol. 2012 Dec 1; 303(11): F1495–F1502. Published online 2012 Oct 10. doi: 10.1152/ajprenal.00415.2012

PMCID:: PMC3532489

Abstract Article

Select item 307498716.

NHE2X3 DKO mice exhibit gender-specific NHE8 compensation

Hua Xu, Jing Li, Rongji Chen, Bo Zhang, Chunhui Wang, Nolan King, Huacong Chen, Fayez K. Ghishan

Am J Physiol Gastrointest Liver Physiol. 2011 Apr; 300(4): G647–G653. Published online 2011 Jan 20. doi: 10.1152/ajpgi.00546.2010

PMCID:: PMC3074987

Abstract Article

Select item 263408517.

The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease

TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij

Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118

PMCID:: PMC2634085

Abstract Article PDF–629K

Select item 722702818.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 645951019.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194