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Select item 110504201.

Is a Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) Polymorphism a Risk Factor for Nephrolithiasis in Sarcoidosis?

Marjolein Drent, Petal Wijnen, Otto Bekers, Aalt Bast

Int J Mol Sci. 2024 Apr; 25(8): 4448. Published online 2024 Apr 18. doi: 10.3390/ijms25084448

PMCID:: PMC11050420

Abstract Article PDF–531K

Select item 108536722.

New insights into the role of VKORC1 polymorphisms for optimal warfarin dose selection in Caribbean Hispanic patients through an external validation of a population PK/PD model

Karine Rodríguez-Fernández, Gledys Reynaldo-Fernández, Stephanie Reyes-González, Camila de las Barreras, Leyanis Rodríguez-Vera, Cornelis Vlaar, Jean-Christophe M. Monbaliu, Torsten Stelzer, Jorge Duconge, Victor Mangas-Sanjuan

Biomed Pharmacother. Author manuscript; available in PMC 2024 Feb 9.

Published in final edited form as: Biomed Pharmacother. 2024 Jan; 170: 115977. Published online 2023 Dec 6. doi: 10.1016/j.biopha.2023.115977

PMCID:: PMC10853672

Abstract Article PDF–883K

Select item 102254823.

Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state

Shuang Li, Jie Sun, Shixuan Liu, Fengbo Zhou, Michael L. Gross, Weikai Li

Blood Adv. 2023 May 23; 7(10): 2271–2282. Published online 2022 Dec 14. doi: 10.1182/bloodadvances.2021006876

PMCID:: PMC10225482

Abstract Article PDF–3.2M

Select item 100878044.

Association of VKORC1 polymorphisms and major bleedings in patients who are treated with vitamin K antagonists

D. Max van Heteren, Willem M. Lijfering, Felix J. M. van der Meer, Pieter H. Reitsma, Jesse J. Swen, Mettine H. A. Bos, Nienke van Rein

J Intern Med. 2023 Jan; 293(1): 124–127. Published online 2022 Sep 20. doi: 10.1111/joim.13569

PMCID:: PMC10087804

Article PDF–192K

Select item 81506625.

Variation in VKORC1 Is Associated with Vascular Dementia

Jure Mur, Daniel L. McCartney, Daniel I. Chasman, Peter M. Visscher, Graciela Muniz-Terrera, Simon R. Cox, Tom C. Russ, Riccardo E. Marioni

J Alzheimers Dis. 2021; 80(3): 1329–1337. Prepublished online 2021 Feb 26. Published online 2021 Apr 6. doi: 10.3233/JAD-201256

PMCID:: PMC8150662

Abstract Article PDF–207K

Select item 79464076.

Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation

Shixuan Liu, Shuang Li, Guomin Shen, Narayanasami Sukumar, Andrzej M. Krezel, Weikai Li

Science. Author manuscript; available in PMC 2021 Mar 10.

Published in final edited form as: Science. 2021 Jan 1; 371(6524): eabc5667. Published online 2020 Nov 5. doi: 10.1126/science.abc5667

PMCID:: PMC7946407

Abstract Article PDF–1.6M

Select item 74626137.

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

Melissa A Chiasson, Nathan J Rollins, Jason J Stephany, Katherine A Sitko, Kenneth A Matreyek, Marta Verby, Song Sun, Frederick P Roth, Daniel DeSloover, Debora S Marks, Allan E Rettie, Douglas M Fowler

eLife. 2020; 9: e58026. Published online 2020 Sep 1. doi: 10.7554/eLife.58026

PMCID:: PMC7462613

Abstract Article PDF–3.9M

Select item 74466148.

Vitamin K epoxide reductase complex subunit 1 (VKORC1) gene polymorphism as determinant of differences in Covid-19-related disease severity

Rob Janssen, Jona Walk

Med Hypotheses. 2020 Nov; 144: 110218. Published online 2020 Aug 25. doi: 10.1016/j.mehy.2020.110218

PMCID:: PMC7446614

Abstract Article PDF–567K

Select item 73638359.

The effect of the VKORC1 promoter variant on warfarin responsiveness in the Saudi WArfarin Pharmacogenetic (SWAP) cohort

Maha Al Ammari, Mohammed AlBalwi, Khizra Sultana, Ibrahim B. Alabdulkareem, Bader Almuzzaini, Nada S. Almakhlafi, Mohammed Aldrees, Jahad Alghamdi

Sci Rep. 2020; 10: 11613. Published online 2020 Jul 15. doi: 10.1038/s41598-020-68519-9

PMCID:: PMC7363835

Abstract Article PDF–1.0M

Select item 672796110.

VKORC1-1639A allele influences warfarin maintenance dosage among Blacks receiving warfarin anticoagulation: a retrospective cohort study

Fatima Donia Mili, Tenecia Allen, Paula Weinstein Wadell, W Craig Hooper, Christine De Staercke, Christopher J Bean, Cathy Lally, Harland Austin, Nanette K Wenger

Future Cardiol. Author manuscript; available in PMC 2019 Sep 5.

Published in final edited form as: Future Cardiol. 2018 Jan; 14(1): 15–26. Published online 2017 Dec 8. doi: 10.2217/fca-2017-0025

PMCID:: PMC6727961

Abstract Article PDF–122K

Select item 671485811.

Genetic Polymorphism of VKORC1-1639 in Children With Intracranial Hemorrhage Due to Vitamin K Deficiency

Uğur Berber, Mehmet Akif Özdemir, Ekrem Unal, Serpil Taheri, Serkan Yildiz, Keziban Korkmaz Bayramov, Yunus Güler, Hüseyin Per

Clin Appl Thromb Hemost. 2018 Dec; 24(9 Suppl): 89S–93S. Published online 2018 Aug 13. doi: 10.1177/1076029618792302

PMCID:: PMC6714858

Abstract Article PDF–159K

Select item 639965912.

Is there any association between osteoporotic vertebral fracture and vitamin K epoxide reductase complex subunit-1 polymorphism in Turkish society? A pilot study

Merih Ozgen, Didem Turgut Cosan, Fulya Doganer, Ahu Soyocak, Onur Armagan, Selen Kuzgun, Ayse Merve Aydogan, Hasan Veysi Gunes, Irfan Degirmenci, Fezan Mutlu

Clinics (Sao Paulo) 2019; 74: e739. Published online 2019 Mar 5. doi: 10.6061/clinics/2019/e739