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Items: 1 to 20 of 51

1.
Intellectual disability associated with a homozygous missense mutation in THOC6
Chandree L Beaulieu, Lijia Huang, A Micheil Innes, Marie-Andree Akimenko, Erik G Puffenberger, Charles Schwartz, Paul Jerry, Carole Ober, Robert A Hegele, D Ross McLeod, Jeremy Schwartzentruber, Jacek Majewski, Dennis E Bulman, Jillian S Parboosingh, Kym M Boycott
Orphanet J Rare Dis. 2013; 8: 62. Published online 2013 Apr 26. doi: 10.1186/1750-1172-8-62
PMCID:
PMC3644499
AbstractArticlePDF–811K
2.
Recruitment of the Complete hTREX Complex Is Required for Kaposi's Sarcoma–Associated Herpesvirus Intronless mRNA Nuclear Export and Virus Replication
James R. Boyne, Kevin J. Colgan, Adrian Whitehouse
PLoS Pathog. 2008 Oct; 4(10): e1000194. Published online 2008 Oct 31. doi: 10.1371/journal.ppat.1000194
PMCID:
PMC2569588
AbstractArticlePDF–838K
3.
Recruitment of the human TREX complex to mRNA during splicing
Seiji Masuda, Rita Das, Hong Cheng, Ed Hurt, Nijsje Dorman, Robin Reed
Genes Dev. 2005 Jul 1; 19(13): 1512–1517. doi: 10.1101/gad.1302205
PMCID:
PMC1172058
AbstractArticlePDF–356K
4.
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006
PMCID:
PMC9753471
AbstractArticlePDF–4.3M
5.
Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser, Dexter Jin, Ania Wronski, Stephen J. Elledge, Charlotte Kuperwasser
Cell Rep. Author manuscript; available in PMC 2020 Jun 16.
Published in final edited form as: Cell Rep. 2019 Sep 24; 28(13): 3435–3449.e5. doi: 10.1016/j.celrep.2019.08.060
PMCID:
PMC7297508
AbstractArticlePDF–2.4M
6.
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity
Oliver Stehling, Ajay A. Vashisht, Judita Mascarenhas, Zophonias O. Jonsson, Tanu Sharma, Daili J.A. Netz, Antonio J. Pierik, James A. Wohlschlegel, Roland Lill
Science. Author manuscript; available in PMC 2013 Jan 13.
Published in final edited form as: Science. 2012 Jul 13; 337(6091): 195–199. Published online 2012 Jun 7. doi: 10.1126/science.1219723
PMCID:
PMC3420340
AbstractArticlePDF–1.8M
7.
RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma
E Viziteu, B Klein, J Basbous, Y-L Lin, C Hirtz, C Gourzones, L Tiers, A Bruyer, L Vincent, C Grandmougin, A Seckinger, H Goldschmidt, A Constantinou, P Pasero, D Hose, J Moreaux
Leukemia. 2017 Oct; 31(10): 2104–2113. Prepublished online 2017 Feb 10. Published online 2017 Mar 10. doi: 10.1038/leu.2017.54
PMCID:
PMC5629372
AbstractArticlePDF–2.9M
8.
Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production
Souad Naji, Géza Ambrus, Peter Cimermančič, Jason R. Reyes, Jeffrey R. Johnson, Rebecca Filbrandt, Michael D. Huber, Paul Vesely, Nevan J. Krogan, John R. Yates, III, Andrew C. Saphire, Larry Gerace
Mol Cell Proteomics. 2012 Apr; 11(4): M111.015313. Published online 2011 Dec 15. doi: 10.1074/mcp.M111.015313
PMCID:
PMC3322577
AbstractArticlePDF–1.4M
9.
A functional reference map of the RNF8 interactome in cancer
Chuanyang Liu, Jingyu Kuang, Yuxuan Wang, Ting Duan, Lu Min, Chenyu Lu, Tianyi Zhang, Ruifen Chen, Ying Wu, Lingyun Zhu
Biol Direct. 2022; 17: 17. Published online 2022 Jul 13. doi: 10.1186/s13062-022-00331-z
PMCID:
PMC9277853
AbstractArticlePDF–5.9M
10.
Characterizing WW Domain Interactions of Tumor Suppressor WWOX Reveals Its Association with Multiprotein Networks
Mohammad Abu-Odeh, Tomer Bar-Mag, Haiming Huang, TaeHyung Kim, Zaidoun Salah, Suhaib K. Abdeen, Marius Sudol, Dana Reichmann, Sachdev Sidhu, Philip M. Kim, Rami I. Aqeilan
J Biol Chem. 2014 Mar 28; 289(13): 8865–8880. Published online 2014 Feb 18. doi: 10.1074/jbc.M113.506790
PMCID:
PMC3979411
AbstractArticlePDF–3.0M
11.
Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis
Weicheng Zang, Chuanzhen Yang, Tingting Li, Liming Liao, Xiaofeng Zheng
Proc Natl Acad Sci U S A. 2019 Dec 17; 116(51): 25624–25633. Published online 2019 Dec 3. doi: 10.1073/pnas.1910250116
PMCID:
PMC6926050
AbstractArticlePDF–1.4M
12.
Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins
Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki, Jaya Gangopadhyay, Steven P. Gygi, Robin Reed
Sci Rep. 2018; 8: 8755. Published online 2018 Jun 8. doi: 10.1038/s41598-018-27136-3
PMCID:
PMC5993797
AbstractArticlePDF–2.9M
13.
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity
HD Hosgood, III, L Zhang, M Shen, SI Berndt, R Vermeulen, G Li, S Yin, M Yeager, J Yuenger, N Rothman, S Chanock, M Smith, Q Lan
Occup Environ Med. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Occup Environ Med. 2009 Dec; 66(12): 848–853. Published online 2009 Sep 22. doi: 10.1136/oem.2008.044024
PMCID:
PMC2928224
AbstractArticlePDF–321K
14.
Insights into the ubiquitin-proteasome system of human embryonic stem cells
Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez
Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9
PMCID:
PMC5840266
AbstractArticlePDF–2.9M
15.
Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS
Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda
Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.
Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012
PMCID:
PMC5849534
AbstractArticlePDF–1.1M
16.
PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry
Alexandre Maréchal, Ju-Mei Li, Xiao Ye Ji, Ching-Shyi Wu, Stephanie A. Yazinski, Hai Dang Nguyen, Shizhou Liu, Amanda E. Jiménez, Jianping Jin, Lee Zou
Mol Cell. Author manuscript; available in PMC 2015 Jan 23.
Published in final edited form as: Mol Cell. 2014 Jan 23; 53(2): 235–246. Published online 2013 Dec 12. doi: 10.1016/j.molcel.2013.11.002
PMCID:
PMC3946837
AbstractArticlePDF–2.0M
17.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord
Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6
PMCID:
PMC8760077
AbstractArticlePDF–12M
18.
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras
Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006
PMCID:
PMC6375729
AbstractArticlePDF–10M
19.
A protein interaction landscape of breast cancer
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J. McGregor, Patrick O’Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ’t Veer, Alan Ashworth, Trey Ideker, Nevan Krogan
Science. Author manuscript; available in PMC 2022 Apr 26.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf3066. Published online 2021 Oct 1. doi: 10.1126/science.abf3066
PMCID:
PMC9040556
AbstractArticlePDF–2.2M
20.
KAP1 facilitates reinstatement of heterochromatin after DNA replication
Suk Min Jang, Annamaria Kauzlaric, Jean-Pierre Quivy, Julien Pontis, Benjamin Rauwel, Andrea Coluccio, Sandra Offner, Julien Duc, Priscilla Turelli, Geneviève Almouzni, Didier Trono
Nucleic Acids Res. 2018 Sep 28; 46(17): 8788–8802. Published online 2018 Jun 28. doi: 10.1093/nar/gky580
PMCID:
PMC6158507
AbstractArticlePDF–9.4M

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