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Select item 100831031.

Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration

Carey Y. L. Huh, Henri Leinonen, Taylor Nakayama, Julia R. Tomasello, Jianye Zhang, Jack Zeitoun, John P. Peach, Maximilian Halabi, Jianying Z. Kiser, Krzysztof Palczewski, Philip D. Kiser, Sunil P. Gandhi

Curr Biol. Author manuscript; available in PMC 2023 Oct 24.

Published in final edited form as: Curr Biol. 2022 Oct 24; 32(20): 4538–4546.e5. Published online 2022 Sep 23. doi: 10.1016/j.cub.2022.09.005

PMCID:: PMC10083103

Abstract Article PDF–2.3M

Select item 99873312.

Vitamin A regulates tissue-specific organ remodeling in diet-induced obesity independent of mitochondrial function

Ivanna Shymotiuk, Natali Froese, Christopher Werlein, Lea Naasner, Malgorzata Szaroszyk, Mark P. Kühnel, Danny D. Jonigk, William S. Blaner, Adam R. Wende, E. Dale Abel, Johann Bauersachs, Christian Riehle

Front Endocrinol (Lausanne) 2023; 14: 1118751. Published online 2023 Feb 20. doi: 10.3389/fendo.2023.1118751

PMCID:: PMC9987331

Abstract Article PDF–4.4M

Select item 74842803.

Mycobacterium tuberculosis Infection is Exacerbated in Mice Lacking Lecithin:Retinol Acyltransferase.

Steven E. Trasino, Xiao-Han Tang, Carolina Trujillo, Jaclynn Andres, Sabine Ehrt, Lorraine J. Gudas

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2020 Nov 1; 1866(11): 165909. Published online 2020 Aug 5. doi: 10.1016/j.bbadis.2020.165909

PMCID:: PMC7484280

Article PDF–517K

Select item 74158944.

All-trans-Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

Alyssa Dreffs, Cheng-Mao Lin, Xuwen Liu, Sumathi Shanmugam, Steven F. Abcouwer, Timothy S. Kern, David A. Antonetti

Invest Ophthalmol Vis Sci. 2020 Jun; 61(6): 8. Published online 2020 Jun 3. doi: 10.1167/iovs.61.6.8

PMCID:: PMC7415894

Abstract Article PDF–1.5M

Select item 58786775.

Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs

Songqi Gao, Shirin Kahremany, Jianye Zhang, Beata Jastrzebska, Janice Querubin, Simon M. Petersen-Jones, Krzysztof Palczewski

Mol Pharmacol. 2018 May; 93(5): 438–452. Published online 2018 May. doi: 10.1124/mol.117.111294

PMCID:: PMC5878677

Abstract Article PDF–1.7M

Select item 49355146.

Effects of vitamin A deficiency in the postnatal mouse heart: role of hepatic retinoid stores

Mary Ann Asson-Batres, Sergey Ryzhov, Oleg Tikhomirov, Christine W. Duarte, Clare Bates Congdon, Craig R. Lessard, Samuel McFarland, Cecile Rochette-Egly, Truc-Linh Tran, Cristi L. Galindo, Amanda J. Favreau-Lessard, Douglas B. Sawyer

Am J Physiol Heart Circ Physiol. 2016 Jun 1; 310(11): H1773–H1789. Published online 2016 Apr 15. doi: 10.1152/ajpheart.00887.2015

PMCID:: PMC4935514

Abstract Article

Select item 45718817.

Retinylamine Benefits Early Diabetic Retinopathy in Mice

Haitao Liu, Jie Tang, Yunpeng Du, Chieh Allen Lee, Marcin Golczak, Arivalagan Muthusamy, David A. Antonetti, Alexander A. Veenstra, Jaume Amengual, Johannes von Lintig, Krzysztof Palczewski, Timothy S. Kern

J Biol Chem. 2015 Aug 28; 290(35): 21568–21579. Published online 2013 Jul 2. doi: 10.1074/jbc.M115.655555

PMCID:: PMC4571881

Abstract Article PDF–1.6M

Select item 40808918.

Pathophysilogical Mechanism and Treatment Strategies for Leber Congenital Amaurosis

Yingbin Fu, Tao Zhang

Adv Exp Med Biol. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Adv Exp Med Biol. 2014; 801: 791–796. doi: 10.1007/978-1-4614-3209-8_99

PMCID:: PMC4080891

Abstract Article PDF–177K

Select item 36059979.

Hepatic retinoid stores are required for normal liver regeneration

Igor O. Shmarakov, Hongfeng Jiang, Kryscilla Jian Zhang Yang, Ira J. Goldberg, William S. Blaner

J Lipid Res. 2013 Apr; 54(4): 893–908. doi: 10.1194/jlr.M029801

PMCID:: PMC3605997

Abstract Article PDF–2.0M

Select item 346501410.

A Microparticle/Hydrogel Combination Drug-Delivery System for Sustained Release of Retinoids

Song-Qi Gao, Tadao Maeda, Kiichiro Okano, Krzysztof Palczewski

Invest Ophthalmol Vis Sci. 2012 Sep; 53(10): 6314–6323. Published online 2012 Sep 19. doi: 10.1167/iovs.12-10279

PMCID:: PMC3465014

Abstract Article PDF–559K

Select item 339784811.

Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein

Jaume Amengual, Marcin Golczak, Krzysztof Palczewski, Johannes von Lintig

J Biol Chem. 2012 Jul 13; 287(29): 24216–24227. Published online 2012 May 27. doi: 10.1074/jbc.M112.353979

PMCID:: PMC3397848

Abstract Article PDF–1.7M

Select item 338596612.

Chemical Chaperone TUDCA Preserves Cone Photoreceptors in a Mouse Model of Leber Congenital Amaurosis

Tao Zhang, Wolfgang Baehr, Yingbin Fu

Invest Ophthalmol Vis Sci. 2012 Jun; 53(7): 3349–3356. Published online 2012 Jun 5. doi: 10.1167/iovs.12-9851

PMCID:: PMC3385966

Abstract Article PDF–690K

Select item 327126313.

Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration

Yohei Shirakami, Max E. Gottesman, William S. Blaner

Carcinogenesis. 2012 Feb; 33(2): 268–274. Published online 2011 Nov 24. doi: 10.1093/carcin/bgr275

PMCID:: PMC3271263

Abstract Article PDF–609K

Select item 307126714.

Vitamin A Deficiency Results in Meiotic Failure and Accumulation of Undifferentiated Spermatogonia in Prepubertal Mouse Testis

Hui Li, Krzysztof Palczewski, Wolfgang Baehr, Margaret Clagett-Dame

Biol Reprod. 2011 Feb; 84(2): 336–341. Published online 2010 Sep 29. doi: 10.1095/biolreprod.110.086157

PMCID:: PMC3071267

Abstract Article PDF–4.3M

Select item 293795215.

An Acyl-covalent Enzyme Intermediate of Lecithin:Retinol Acyltransferase

Marcin Golczak, Krzysztof Palczewski

J Biol Chem. 2010 Sep 17; 285(38): 29217–29222. Published online 2010 Jul 12. doi: 10.1074/jbc.M110.152314

PMCID:: PMC2937952

Abstract Article PDF–1.7M

Select item 281203616.

Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis

Rebeca Acin-Perez, Beatrice Hoyos, Feng Zhao, Valerie Vinogradov, Donald A. Fischman, Robert A. Harris, Michael Leitges, Nuttaporn Wongsiriroj, William S. Blaner, Giovanni Manfredi, Ulrich Hammerling

FASEB J. 2010 Feb; 24(2): 627–636. doi: 10.1096/fj.09-142281

PMCID:: PMC2812036

Abstract Article

Select item 248643117.

Homeostasis of Retinol in Lecithin:retinol Acyltransferase Gene Knockout Mice Fed a High Retinol Diet

Limin Liu, Xiao-Han Tang, Lorraine J. Gudas

Biochem Pharmacol. Author manuscript; available in PMC 2009 Jun 15.

Published in final edited form as: Biochem Pharmacol. 2008 Jun 15; 75(12): 2316–2324. Published online 2008 Mar 27. doi: 10.1016/j.bcp.2008.03.012

PMCID:: PMC2486431

Abstract Article PDF–444K

Select item 127427918.

Pharmacological and rAAV Gene Therapy Rescue of Visual Functions in a Blind Mouse Model of Leber Congenital Amaurosis

Matthew L Batten, Yoshikazu Imanishi, Daniel C Tu, Thuy Doan, Li Zhu, Jijing Pang, Lyudmila Glushakova, Alexander R Moise, Wolfgang Baehr, Russell N. Van Gelder, William W Hauswirth, Fred Rieke, Krzysztof Palczewski

PLoS Med. 2005 Nov; 2(11): e333. Published online 2005 Nov 1. doi: 10.1371/journal.pmed.0020333

PMCID:: PMC1274279

Abstract Article PDF–642K

Select item 568294819.

Impact of LCA-Associated E14L LRAT Mutation on Protein Stability and Retinoid Homeostasis

Sylwia Chelstowska, Made Airanthi K. Widjaja-Adhi, Josie A. Silvaroli, Marcin Golczak

Biochemistry. Author manuscript; available in PMC 2018 Aug 29.

Published in final edited form as: Biochemistry. 2017 Aug 29; 56(34): 4489–4499. Published online 2017 Aug 15. doi: 10.1021/acs.biochem.7b00451

PMCID:: PMC5682948

Abstract Article PDF–977K

Select item 498781420.

Dimerization of visual pigments in vivo

Tao Zhang, Li-Hui Cao, Sandeep Kumar, Nduka O. Enemchukwu, Ning Zhang, Alyssia Lambert, Xuchen Zhao, Alex Jones, Shixian Wang, Emily M. Dennis, Amrita Fnu, Sam Ham, Jon Rainier, King-Wai Yau, Yingbin Fu

Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): 9093–9098. Published online 2016 Jul 26. doi: 10.1073/pnas.1609018113